| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zager RA et al. | Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure. | 1997 | Kidney Int. | pmid:9211347 |
| Oh CS et al. | ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation. | 1997 | J. Biol. Chem. | pmid:9211877 |
| Chigorno V et al. | Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture. | 1997 | J. Lipid Res. | pmid:9215544 |
| Reggiori F et al. | Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae. | 1997 | EMBO J. | pmid:9218793 |
| Paukku T et al. | Novel cationic liposomes for DNA-transfection with high efficiency and low toxicity. | 1997 | Chem. Phys. Lipids | pmid:9219346 |
| Manev H and Cagnoli CM | Ceramide-mediated and isoquinolinesulfonamide-sensitive pathways of neuronal death: anything in common? | 1997 | Neurochem. Int. | pmid:9220452 |
| Nikolova-Karakashian M et al. | Bimodal regulation of ceramidase by interleukin-1beta. Implications for the regulation of cytochrome p450 2C11. | 1997 | J. Biol. Chem. | pmid:9228043 |
| Boneh A et al. | Effect of sphingosine on rat glial cells: inhibition of prostaglandin E2 and insensitivity of nitric oxide generation. | 1997 | Neurosci. Lett. | pmid:9237488 |
| Kishida E et al. | Evaluation of a trans configuration for the apoptosis-inducing activity of ceramide. | 1997 | J Lipid Mediat Cell Signal | pmid:9246602 |
| Kiss Z and Mukherjee JJ | Phosphocholine and sphingosine-1-phosphate synergistically stimulate DNA synthesis by a MAP kinase-dependent mechanism. | 1997 | FEBS Lett. | pmid:9257719 |
| Porpaczy Z et al. | Internalized plasma membrane cholesterol passes through an endosome compartment that is distinct from the acid vesicle-lysosome compartment. | 1997 | Exp. Cell Res. | pmid:9260888 |
| Herrmann JL et al. | Regulation of lipid signaling pathways for cell survival and apoptosis by bcl-2 in prostate carcinoma cells. | 1997 | Exp. Cell Res. | pmid:9260915 |
| Kim SH et al. | Sphingosine stimulates thrombin-induced gelation of the fibrinogen. | 1997 | Thromb. Res. | pmid:9263400 |
| Rodriguez-Lafrasse C et al. | Modulation of protein kinase C by endogenous sphingosine: inhibition of phorbol dibutyrate binding in Niemann-Pick C fibroblasts. | 1997 | Biochem. J. | pmid:9271101 |
| Wieder T et al. | Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues. | 1997 | FEBS Lett. | pmid:9271217 |
| Yamamura S et al. | Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin-insensitive manner. | 1997 | Biochemistry | pmid:9271506 |
| Besancon M et al. | Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents. | 1997 | J. Biol. Chem. | pmid:9278394 |
| Edsall LC et al. | Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. | 1997 | J. Neurosci. | pmid:9278531 |
| Pörn-Ares MI et al. | Induction of apoptosis and potentiation of TNF- and Fas-mediated apoptosis in U937 cells by the xanthogenate compound D609. | 1997 | Exp. Cell Res. | pmid:9281351 |
| Xie H and Johnson GV | Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. | 1997 | J. Neurochem. | pmid:9282924 |
| Mitsusada M et al. | Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY720, in rat small bowel transplantation. | 1997 | Transpl. Int. | pmid:9287398 |
| Orlati S et al. | Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism. | 1997 | Biochim. Biophys. Acta | pmid:9296526 |
| Gudz TI et al. | Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide. | 1997 | J. Biol. Chem. | pmid:9305864 |
| Kozawa O et al. | Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C. | 1997 | J. Biol. Chem. | pmid:9312119 |
| Michel C et al. | Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide. | 1997 | J. Biol. Chem. | pmid:9312549 |
| Prinetti A et al. | Involvement of a ceramide activated protein phosphatase in the differentiation of neuroblastoma Neuro2a cells. | 1997 | FEBS Lett. | pmid:9315744 |
| Tolan D et al. | Sphingosine prevents diacylglycerol signaling to mitogen-activated protein kinase in airway smooth muscle. | 1997 | Am. J. Physiol. | pmid:9316414 |
| Kimura T et al. | Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathway. | 1997 | Am. J. Physiol. | pmid:9316456 |
| Shimojo T et al. | Sphingolipid base metabolism. Stereospecific uptake of proton in the enzymatic conversion of sphinganine 1-phosphate to ethanolamine 1-phosphate. | 1976 | J. Biol. Chem. | pmid:932041 |
| Törnquist K et al. | Sphingosine 1-phosphate mobilizes sequestered calcium, activates calcium entry, and stimulates deoxyribonucleic acid synthesis in thyroid FRTL-5 cells. | 1997 | Endocrinology | pmid:9322911 |
| Sueyoshi N et al. | Preparation of a naturally occurring D-erythro-(2S, 3R)-sphingosylphosphocholine using Shewanella alga NS-589. | 1997 | J. Lipid Res. | pmid:9323602 |
| Caldwell C et al. | Regulatory differences among avian ecto-ATPases. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9325157 |
| Gill ZP et al. | Insulin-like growth factor-binding protein (IGFBP-3) predisposes breast cancer cells to programmed cell death in a non-IGF-dependent manner. | 1997 | J. Biol. Chem. | pmid:9325280 |
| Hristova NI et al. | Sphingosine-mediated electroporative DNA transfer through lipid bilayers. | 1997 | FEBS Lett. | pmid:9326374 |
| Keenan C et al. | Isoform specificity of activators and inhibitors of protein kinase C gamma and delta. | 1997 | FEBS Lett. | pmid:9326378 |
| Saba JD et al. | The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. | 1997 | J. Biol. Chem. | pmid:9334171 |
| Mattson MP et al. | Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. | 1997 | J. Neurosci. Res. | pmid:9335256 |
| Heacock AM and Agranoff BW | Protein kinase inhibitors block neurite outgrowth from explants of goldfish retina. | 1997 | Neurochem. Res. | pmid:9342720 |
| Törnquist K et al. | Sphingosylphosphorylcholine activates an amiloride-insensitive Na+-H+-exchange mechanism in GH4C1 cells. | 1997 | Eur. J. Biochem. | pmid:9346294 |
| Pawelczyk T and Matecki A | Structural requirements of phospholipase C delta1 for regulation by spermine, sphingosine and sphingomyelin. | 1997 | Eur. J. Biochem. | pmid:9346303 |
| Mao C et al. | Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. | 1997 | J. Biol. Chem. | pmid:9353337 |
| Lombardi V et al. | 1H NMR ganglioside ceramide resonance region on the differential diagnosis of low and high malignancy of brain gliomas. | 1997 | Cell. Mol. Neurobiol. | pmid:9353593 |
| Geeraert L et al. | Conversion of dihydroceramide into ceramide: involvement of a desaturase. | 1997 | Biochem. J. | pmid:9355743 |
| Norred WP et al. | Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: specificity of the response and structure-activity relationships. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9356308 |
| Galve-Roperh I et al. | Ceramide-induced translocation of protein kinase C zeta in primary cultures of astrocytes. | 1997 | FEBS Lett. | pmid:9357981 |
| Bielawska AE et al. | Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. | 1997 | Am. J. Pathol. | pmid:9358751 |
| Lozanski G et al. | The sphingomyelin-ceramide pathway participates in cytokine regulation of C-reactive protein and serum amyloid A, but not alpha-fibrinogen. | 1997 | Biochem. J. | pmid:9359864 |
| Xu M et al. | Effect of peritransplant FTY720 alone or in combination with posttransplant FK 506 in a rat model of cardiac allotransplantation. | 1997 | Transplant. Proc. | pmid:9365631 |
| Olivera A et al. | Differential effects of sphingomyelinase and cell-permeable ceramide analogs on proliferation of Swiss 3T3 fibroblasts. | 1997 | Biochim. Biophys. Acta | pmid:9366247 |
| Baker A et al. | Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo. | 1997 | Cancer Res. | pmid:9371519 |
| Kiss Z et al. | Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine. | 1997 | Biochem. J. | pmid:9371692 |
| Shinomiya T et al. | An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60. | 1997 | Immunology | pmid:9378500 |
| Sato K et al. | Exogenous sphingosine 1-phosphate induces neurite retraction possibly through a cell surface receptor in PC12 cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9388477 |
| Chueh SC et al. | Induction of tolerance toward rat cardiac allografts by treatment with allochimeric class I MHC antigen and FTY720. | 1997 | Transplantation | pmid:9392303 |
| Mitsuyoshi H et al. | Ursodeoxycholic acid enhances glucocorticoid-induced tyrosine aminotransferase-gene expression in cultured rat hepatocytes. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9398635 |
| Wiktorek-Wójcik M et al. | Serine base exchange enzyme activity is modulated by sphingosine and other amphiphilic compounds: possible role of positive charge in increasing the synthesis of phosphatidylserine. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9405236 |
| Yatomi Y et al. | N,N-dimethylsphingosine 1-phosphate activates human platelets. | 1997 | FEBS Lett. | pmid:9409747 |
| Kozawa O et al. | Activation of mitogen-activated protein kinase is involved in sphingosine 1-phosphate-stimulated interleukin-6 synthesis in osteoblasts. | 1997 | FEBS Lett. | pmid:9414115 |
| Jarvis WD et al. | Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine. | 1997 | Mol. Pharmacol. | pmid:9415703 |
| Titievsky A et al. | Sphingosine inhibits voltage-operated calcium channels in GH4C1 cells. | 1998 | J. Biol. Chem. | pmid:9417071 |
| Mandala SM et al. | Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9419344 |
| van Echten-Deckert G et al. | 1-Methylthiodihydroceramide, a novel analog of dihydroceramide, stimulates sphinganine degradation resulting in decreased de novo sphingolipid biosynthesis. | 1998 | J. Biol. Chem. | pmid:9422785 |
| Ku WC et al. | Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9434777 |
| Tanabe F et al. | Ceramide promotes calpain-mediated proteolysis of protein kinase C beta in murine polymorphonuclear leukocytes. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9439623 |
| Hashizume T et al. | Sphingosine enhances arachidonic acid liberation in response to U46619 through an increase in phospholipase A2 activity in rabbit platelets. | 1997 | J. Biochem. | pmid:9443821 |
| Skrzypek MS et al. | Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae. | 1998 | J. Biol. Chem. | pmid:9446592 |
| Cuvillier O et al. | Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. | 1998 | J. Biol. Chem. | pmid:9446602 |
| Conway AM et al. | Sphingosine 1-phosphate activation of MAP kinase--involvement of PI 3-kinase and protein kinase C. | 1997 | Biochem. Soc. Trans. | pmid:9450013 |
| Keenan C et al. | Assay to determine the isoform specificity of protein kinase C inhibitors. | 1997 | Biochem. Soc. Trans. | pmid:9450019 |
| Zehavi U | Synthesis of potentially caged sphingolipids, possible precursors of cellular modulators and second messengers. | 1997 | Chem. Phys. Lipids | pmid:9450322 |
| Kaneshiro ES et al. | Identification and initial characterizations of free, glycosylated, and phosphorylated ceramides of Paramecium. | 1997 | J. Lipid Res. | pmid:9458264 |
| Kawa S et al. | Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate. | 1997 | FEBS Lett. | pmid:9459309 |
| Chigorno V et al. | Metabolic processing of gangliosides by human fibroblasts in culture--formation and recycling of separate pools of sphingosine. | 1997 | Eur. J. Biochem. | pmid:9461288 |
| Zhou J and Saba JD | Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9464245 |
| Maguer-Satta V et al. | BCR-ABL accelerates C2-ceramide-induced apoptosis. | 1998 | Oncogene | pmid:9464542 |
| Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
| Lawler JF et al. | Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. | 1998 | J. Biol. Chem. | pmid:9478955 |
| Reunanen N et al. | Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. | 1998 | J. Biol. Chem. | pmid:9478967 |
| Zondag GC et al. | Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. | 1998 | Biochem. J. | pmid:9480864 |
| Kim BC and Kim JH | Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway. | 1998 | Biochem. J. | pmid:9480923 |
| Sakai T et al. | Effects of alpha- and beta-galactosylated C2-ceramides on the immune system. | 1998 | J. Med. Chem. | pmid:9484513 |
| Simon CG and Gear AR | Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. | 1998 | Biochemistry | pmid:9485333 |
| Lee MJ et al. | Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. | 1998 | Science | pmid:9488656 |
| Takeda H et al. | Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. | 1998 | FEBS Lett. | pmid:9490019 |
| Lee SC et al. | The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway. | 1998 | J. Protein Chem. | pmid:9491924 |
| Monney L et al. | Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis. | 1998 | Eur. J. Biochem. | pmid:9492297 |
| Muramatsu K et al. | A new immunosuppressant, FTY720, prolongs limb allograft survival in rats. | 1998 | Ann Plast Surg | pmid:9495465 |
| Igarashi Y | Functional roles of sphingosine, sphingosine 1-phosphate, and methylsphingosines: in regard to membrane sphingolipid signaling pathways. | 1997 | J. Biochem. | pmid:9498549 |
| Wakita H et al. | Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. | 1998 | J. Invest. Dermatol. | pmid:9506444 |
| Berger A et al. | The potent lipid mitogen sphingosylphosphocholine activates the DNA binding activity of upstream stimulating factor (USF), a basic helix-loop-helix-zipper protein. | 1998 | Biochim. Biophys. Acta | pmid:9507145 |
| Czajkowski R et al. | Sphingosine modulates Ca2+ signals via phospholipase C dependent pathway in glioma C6 cells. | 1997 | Acta Neurobiol Exp (Wars) | pmid:9519554 |
| Galvan V and Roizman B | Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9520470 |
| Crilly KS et al. | The choline kinase inhibitor hemicholinium-3 can inhibit mitogen-induced DNA synthesis independent of its effect on phosphocholine formation. | 1998 | Arch. Biochem. Biophys. | pmid:9521826 |
| Bokoch GM et al. | A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids. | 1998 | J. Biol. Chem. | pmid:9525917 |
| Foghi A et al. | Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. | 1998 | Endocrinology | pmid:9528992 |
| Flores I et al. | Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. | 1998 | J. Immunol. | pmid:9531315 |
| Veldman RJ et al. | Metabolism and apoptotic properties of elevated ceramide in HT29rev cells. | 1998 | Biochem. J. | pmid:9531498 |
| Hamada K et al. | Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9535736 |
| Searl TJ and Silinsky EM | Increases in acetylcholine release produced by phorbol esters are not mediated by protein kinase C at motor nerve endings. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9536018 |
| Kao MC et al. | In vitro gene transfer in mammalian cells via a new cationic liposome formulation. | 1998 May-Jun | Oncol. Rep. | pmid:9538164 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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