Kulinski JM et al. |
Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. |
2016 |
Eur. J. Pharmacol. |
pmid:25941085
|
Al Fadel F et al. |
Involvement of Sphingosine 1-Phosphate in Palmitate-Induced Non-Alcoholic Fatty Liver Disease. |
2016 |
Cell. Physiol. Biochem. |
pmid:28006772
|
Bigaud M et al. |
Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism. |
2016 |
PLoS ONE |
pmid:28005953
|
Surya VN et al. |
Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. |
2016 |
J R Soc Interface |
pmid:27974574
|
Zamora-Pineda J et al. |
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. |
2016 |
J. Exp. Med. |
pmid:27810923
|
Kobayashi N et al. |
Fluorescence-based rapid measurement of sphingosine-1-phosphate transport activity in erythrocytes. |
2016 |
J. Lipid Res. |
pmid:27655910
|
Lepannetier S et al. |
Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. |
2016 |
Cell Calcium |
pmid:27638096
|
Kemppainen K et al. |
Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. |
2016 |
Cell. Signal. |
pmid:27634386
|
Viswanathan P et al. |
Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27473658
|
Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
pmid:27467777
|
Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
pmid:27459945
|
Poissonnier A et al. |
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
pmid:27438772
|
Hollands A et al. |
Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. |
2016 |
J. Biol. Chem. |
pmid:27226531
|
Mirzaian M et al. |
Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard. |
2016 |
Clin. Chim. Acta |
pmid:27221202
|
Bao XH et al. |
[Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes]. |
2016 |
Zhonghua Xin Xue Guan Bing Za Zhi |
pmid:27220580
|
Marfia G et al. |
The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling. |
2016 |
Stem Cells Dev. |
pmid:27217090
|
Fleming JK et al. |
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
pmid:27444045
|
Adams DR et al. |
Sphingosine Kinases: Emerging Structure-Function Insights. |
2016 |
Trends Biochem. Sci. |
pmid:27021309
|
Puli MR et al. |
Stomatal closure induced by phytosphingosine-1-phosphate and sphingosine-1-phosphate depends on nitric oxide and pH of guard cells in Pisum sativum. |
2016 |
Planta |
pmid:27233507
|
Bien-Möller S et al. |
Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. |
2016 |
Oncotarget |
pmid:26887055
|
Uranbileg B et al. |
Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. |
2016 |
PLoS ONE |
pmid:26886371
|
Chumanevich A et al. |
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. |
2016 |
Mediators Inflamm. |
pmid:26884643
|
Pastor-Flores D et al. |
Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian PDK1. |
2016 |
Biochim. Biophys. Acta |
pmid:26743850
|
Ghasemi R et al. |
Integrated sphingosine-1 phosphate signaling in the central nervous system: From physiological equilibrium to pathological damage. |
2016 |
Pharmacol. Res. |
pmid:26772814
|
Morel S et al. |
Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43. |
2016 |
Cardiovasc. Res. |
pmid:26762268
|
Sundaram K et al. |
Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death. |
2016 |
Biochem. J. |
pmid:26747710
|
Abu Khweek A et al. |
The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. |
2016 |
PLoS ONE |
pmid:26741365
|
Maczis M et al. |
Sphingosine-1-phosphate and estrogen signaling in breast cancer. |
2016 |
Adv Biol Regul |
pmid:26601898
|
Zhang F et al. |
Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:26589326
|
Pyne NJ and Tigyi GJ |
A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research. |
2016 |
Prog. Lipid Res. |
pmid:26584871
|
Rana A and Sharma S |
Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
pmid:26582369
|
Li S et al. |
Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression. |
2016 |
Oncotarget |
pmid:27811358
|
Priyadarsini S et al. |
Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma. |
2016 |
Exp. Eye Res. |
pmid:27742548
|
Veltman M et al. |
Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. |
2016 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:27663991
|
Scotti L et al. |
Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome. |
2016 |
Mol. Hum. Reprod. |
pmid:27645281
|
Fischer C et al. |
Aptamer-based trapping of phytosphingosine in urine samples. |
2016 |
J. Biotechnol. |
pmid:27637314
|
Nigro E et al. |
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation. |
2016 |
Pharmacol. Res. |
pmid:26462929
|
Sonnenberger S et al. |
Synthesis of ceramides NS and NP with perdeuterated and specifically ω deuterated N-acyl residues. |
2016 |
J Labelled Comp Radiopharm |
pmid:27634543
|
Uemura M et al. |
Inhibitory Effect of Dihydrosphingosine with α-Tocopherol on Volatile Formation during the Autoxidation of Polyunsaturated Triacylglycerols. |
2016 |
J Oleo Sci |
pmid:27477074
|
Liu B et al. |
Synthetic Studies on a Pachastrissamine Sulfur Analogue: Synthesis of a 4-epi-Sulfur Analogue. |
2016 |
Chem. Pharm. Bull. |
pmid:27039834
|
Benaim G et al. |
Sphingosine inhibits the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) activity. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27033604
|
Masching S et al. |
Gastrointestinal Degradation of Fumonisin Bâ‚ by Carboxylesterase FumD Prevents Fumonisin Induced Alteration of Sphingolipid Metabolism in Turkey and Swine. |
2016 |
Toxins (Basel) |
pmid:27007395
|
Güntert T et al. |
1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling. |
2016 |
Neuropharmacology |
pmid:27016021
|
Zhang L et al. |
Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. |
2016 |
Microcirculation |
pmid:27015105
|
Mezeiová E et al. |
Total synthesis and antiproliferative/cytotoxic profiling of 2-epi-jaspine B. |
2016 |
Carbohydr. Res. |
pmid:26895543
|
Kolb JP and Martinez J |
Bon EPOtit! S1P-Mediated EPO Signaling Whets a Macrophage's Appetite for Apoptotic Cells. |
2016 |
Immunity |
pmid:26885850
|
Cohen MV et al. |
Cangrelor-Mediated Cardioprotection Requires Platelets and Sphingosine Phosphorylation. |
2016 |
Cardiovasc Drugs Ther |
pmid:26780906
|
Fang J et al. |
N,N-dimethylsphingosine attenuates myocardial ischemia-reperfusion injury by recruiting regulatory T cells through PI3K/Akt pathway in mice. |
2016 |
Basic Res. Cardiol. |
pmid:27048490
|
Tani K et al. |
Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea. |
2016 |
Neurotox Res |
pmid:26472207
|
Kim BJ et al. |
The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. |
2016 |
J. Endocrinol. Invest. |
pmid:26219613
|
Bakshi R and Häring DA |
Comment on "Fingolimod effects on left ventricular function in multiple sclerosis" Mult Scler 2015. |
2016 |
Mult. Scler. |
pmid:26359277
|
Balakrishnan P et al. |
Ceramide and N,N,N-Trimethylphytosphingosine-Iodide (TMP-I)-Based Lipid Nanoparticles for Cancer Therapy. |
2016 |
Pharm. Res. |
pmid:26337769
|
Medina CB and Ravichandran KS |
Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. |
2016 |
Cell Death Differ. |
pmid:26891690
|
Powell JA et al. |
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. |
2017 |
Blood |
pmid:27956387
|
Miyabe C et al. |
A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. |
2017 |
Inflamm. Res. |
pmid:27942751
|
Engel N et al. |
Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-Regulation. |
2017 |
PLoS ONE |
pmid:28125641
|
Zhao Z et al. |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720. |
2017 |
Acta Haematol. |
pmid:27802432
|
González-Fernández B et al. |
Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells. |
2017 |
Biofactors |
pmid:27801960
|
Syed SN et al. |
S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1 or Lipocalin-2. |
2017 |
Mediators Inflamm. |
pmid:28804221
|
Doan NB et al. |
Acid ceramidase confers radioresistance to glioblastoma cells. |
2017 |
Oncol. Rep. |
pmid:28765947
|
Arish M et al. |
Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies. |
2017 |
J. Recept. Signal Transduct. Res. |
pmid:28758826
|
Song L et al. |
Urine Metabonomics Reveals Early Biomarkers in Diabetic Cognitive Dysfunction. |
2017 |
J. Proteome Res. |
pmid:28722418
|
Polzin A et al. |
Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease. |
2017 |
J. Mol. Cell. Cardiol. |
pmid:28709768
|
Innamorati G et al. |
Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. |
2017 |
Cell Death Dis |
pmid:28703804
|
Bougault C et al. |
Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. |
2017 |
Bone |
pmid:28684192
|
Tsai CH et al. |
Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. |
2017 |
Mol Oncol |
pmid:28672103
|
Hajny S and Christoffersen C |
A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
2017 |
Int J Mol Sci |
pmid:28749426
|
Bertlich M et al. |
Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. |
2017 |
Otol. Neurotol. |
pmid:28742634
|
Koch A et al. |
Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients. |
2017 |
Int J Mol Sci |
pmid:28714882
|
Yanagawa D et al. |
Synthesis and degradation of long-chain base phosphates affect fumonisin B-induced cell death in Arabidopsis thaliana. |
2017 |
J. Plant Res. |
pmid:28303405
|
Oh YT et al. |
DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion. |
2017 |
Cell Commun. Signal |
pmid:28482915
|
Tessema EN et al. |
Isolation and structural characterization of glucosylceramides from Ethiopian plants by LC/APCI-MS/MS. |
2017 |
J Pharm Biomed Anal |
pmid:28463779
|
Fan Q et al. |
Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. |
2017 |
Oncotarget |
pmid:28460443
|
Calderón R et al. |
Stereoselective preparation of quaternary 2-vinyl sphingosines and ceramides and their effect on basal sphingolipid metabolism. |
2017 |
Chem. Phys. Lipids |
pmid:28445710
|
Lafargue A et al. |
Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation. |
2017 |
Free Radic. Biol. Med. |
pmid:28431961
|
Yu M et al. |
The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations. |
2017 |
Int J Mol Sci |
pmid:28287417
|
Patmanathan SN et al. |
Mechanisms of sphingosine 1-phosphate receptor signalling in cancer. |
2017 |
Cell. Signal. |
pmid:28302566
|
Fan C et al. |
Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells. |
2017 |
Neurosci. Lett. |
pmid:28288862
|
Rothhammer V et al. |
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation. |
2017 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:28167760
|
Moritz E et al. |
Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. |
2017 |
Clin. Chim. Acta |
pmid:28159438
|
Lin MH et al. |
Linear ion-trap MS with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis. |
2017 |
J. Lipid Res. |
pmid:28154204
|
Winkler MS et al. |
Sphingosine-1-Phosphate: A Potential Biomarker and Therapeutic Target for Endothelial Dysfunction and Sepsis? |
2017 |
Shock |
pmid:27922551
|
Hindle SJ et al. |
A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline. |
2017 |
Neurobiol. Dis. |
pmid:27913291
|
Al-Jarallah A and Oriowo M |
The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
2017 |
PLoS ONE |
pmid:28493876
|
Beider K et al. |
The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway. |
2017 |
Clin. Cancer Res. |
pmid:27697999
|
Cubells-Baeza N et al. |
Identification of the ligand of Pru p 3, a peach LTP. |
2017 |
Plant Mol. Biol. |
pmid:28299506
|
Nicholas SE et al. |
Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. |
2017 |
PLoS ONE |
pmid:28806736
|
Lee SY et al. |
Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. |
2017 |
Diabetes |
pmid:28698261
|
Jang Y et al. |
Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. |
2017 |
J. Nutr. Biochem. |
pmid:28456081
|
Hutami IR et al. |
Fas/S1P crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:28687489
|
Cannavo A et al. |
β-Blockade Prevents Post-Ischemic Myocardial Decompensation Via βAR-Dependent Protective Sphingosine-1 Phosphate Signaling. |
2017 |
J. Am. Coll. Cardiol. |
pmid:28683966
|
Ko J et al. |
Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28492873
|
Zhang H et al. |
Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. |
2017 |
Vascul. Pharmacol. |
pmid:28797762
|
Navarrete A et al. |
A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. |
2017 |
J Pharm Biomed Anal |
pmid:28314215
|
Shirakawa H et al. |
Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. |
2017 |
Glia |
pmid:28300348
|
Dyckman AJ |
Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P) Agonists and Future Perspectives. |
2017 |
J. Med. Chem. |
pmid:28291340
|
Dela Paz NG et al. |
Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. |
2017 |
Am. J. Physiol., Cell Physiol. |
pmid:28148497
|
Green CL et al. |
The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. |
2017 |
Aging Cell |
pmid:28139067
|
Vishwakarma S et al. |
Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. |
2017 |
Cancer Invest. |
pmid:28135860
|
Kurano M et al. |
Involvement of CETP (Cholesteryl Ester Transfer Protein) in the Shift of Sphingosine-1-Phosphate Among Lipoproteins and in the Modulation of its Functions. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28126827
|