sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Ogle ME et al. Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche. 2017 Stem Cells pmid:28026131
Yung BS et al. Selective coupling of the S1P receptor subtype to S1P-mediated RhoA activation and cardioprotection. 2017 J. Mol. Cell. Cardiol. pmid:28017639
Contaifer D et al. Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients. 2017 J. Lipid Res. pmid:27993949
Myśliwiec H et al. Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. 2017 Arch. Dermatol. Res. pmid:27988894
Zhao Z et al. Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720. 2017 Acta Haematol. pmid:27802432
González-Fernández B et al. Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells. 2017 Biofactors pmid:27801960
Mendelson K et al. The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. 2017 Elife pmid:28956531
Jiang S et al. C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. 2017 Appl. Microbiol. Biotechnol. pmid:27807662
Baek S et al. DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. 2017 Proteomics pmid:28949093
Smith P et al. Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. 2017 Int J Mol Sci pmid:28934113
Jiang R et al. Protein kinase Cα stimulates hypoxia‑induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal‑regulated kinase 1/2 pathway. 2017 Mol Med Rep pmid:28901444
Anjum I et al. Enhancement of S1P-induced contractile response in detrusor smooth muscle of rats having cystitis. 2017 Eur. J. Pharmacol. pmid:28882559
Mitroi DN et al. SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production. 2017 Autophagy pmid:28521611
Leo A et al. The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. 2017 CNS Neurol Disord Drug Targets pmid:27823573
Roch L et al. High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. 2017 Mol. Neurobiol. pmid:27631876
Becker KA et al. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. 2017 Cell. Physiol. Biochem. pmid:29040968
Reinhard NR et al. The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. 2017 Mol. Biol. Cell pmid:28954861
Natarajan V et al. Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. 2017 BMC Genomics pmid:28851267
Kurano M et al. Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. 2017 PLoS ONE pmid:28494002
Azimzadeh K et al. Evaluation of plasma sphingosine 1-phosphate, hepcidin and cardiovascular damage biomarkers (cardiac troponin I and homocysteine) in rats infected with brucellosis and vaccinated (Rev-1, RB-51). 2017 Microb. Pathog. pmid:28533142
Dany M Sphingosine metabolism as a therapeutic target in cutaneous melanoma. 2017 Transl Res pmid:28528915
Chen Y et al. Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE mice fed a high-fat diet. 2017 Atherosclerosis pmid:28527370
Martin GE et al. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. 2017 Biochimie pmid:28341550
Separovic D et al. Altered Levels of Serum Ceramide, Sphingosine and Sphingomyelin Are Associated with Colorectal Cancer: A Retrospective Pilot Study. 2017 Anticancer Res. pmid:28314284
Sun XJ et al. Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis. 2017 Nephrol. Dial. Transplant. pmid:28206609
Janecke AR et al. Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. 2017 Hum. Mutat. pmid:28181337
Jafurulla M et al. Sphingolipids modulate the function of human serotonin receptors: Insights from sphingolipid-deficient cells. 2017 Biochim. Biophys. Acta pmid:27984018
Beider K et al. The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway. 2017 Clin. Cancer Res. pmid:27697999
Gudipaty SA and Rosenblatt J Epithelial cell extrusion: Pathways and pathologies. 2017 Semin. Cell Dev. Biol. pmid:27212253
Kwon SB et al. Phytosphingosine-1-phosphate and epidermal growth factor synergistically restore extracellular matrix in human dermal fibroblasts in vitro and in vivo. 2017 Int. J. Mol. Med. pmid:28204807
Mensah SA et al. Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication. 2017 PLoS ONE pmid:29023478
Wang X et al. Sphingosine 1-phosphate alleviates Coxsackievirus B3-induced myocarditis by increasing invariant natural killer T cells. 2017 Exp. Mol. Pathol. pmid:28986246
Werth S et al. Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism. 2017 J. Endocrinol. pmid:28970286
Du Y et al. Exosomes from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells (hiPSC-MSCs) Protect Liver against Hepatic Ischemia/ Reperfusion Injury via Activating Sphingosine Kinase and Sphingosine-1-Phosphate Signaling Pathway. 2017 Cell. Physiol. Biochem. pmid:28934733
Kuchler L et al. Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis. 2017 Mol. Immunol. pmid:28846923
Dany M and Elston D Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. 2017 J. Am. Acad. Dermatol. pmid:28551069
Mendoza A et al. Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. 2017 Nature pmid:28538737
Ma S et al. A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. 2017 Dev. Cell pmid:28535372
Meshcheryakova A et al. Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. 2017 Expert Opin. Ther. Targets pmid:28524744
Wollny T et al. Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. 2017 Int J Mol Sci pmid:28362332
Denimal D et al. Impairment of the Ability of HDL From Patients With Metabolic Syndrome but Without Diabetes Mellitus to Activate eNOS: Correction by S1P Enrichment. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:28360087
Gusman DH and Shoemake C Evaluation and Optimization of designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis. 2017 Yale J Biol Med pmid:28356890
Andrieu G et al. Sphingosine 1-phosphate signaling through its receptor S1P promotes chromosome segregation and mitotic progression. 2017 Sci Signal pmid:28351953
Becker S et al. Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. 2017 PLoS ONE pmid:28334008
Karunakaran I and van Echten-Deckert G Sphingosine 1-phosphate - A double edged sword in the brain. 2017 Biochim. Biophys. Acta pmid:28315304
Rieck M et al. Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. 2017 Eur. J. Immunol. pmid:28198542
Bruno M et al. Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. 2017 Biochim. Biophys. Acta pmid:28188805
Qi H et al. Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. 2017 J. Lipid Res. pmid:28188148
Ren K et al. ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. 2017 J. Physiol. Biochem. pmid:28181168
Ruiz M et al. HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. 2017 Lipids Health Dis pmid:28179022
Moruno-Manchon JF et al. Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. 2017 Hum. Mol. Genet. pmid:28175299
Rojas-Canales D et al. Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. 2017 Diabetes pmid:28174291
Abe A et al. Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2. 2017 J. Lipid Res. pmid:27993948
Tang HB et al. S1P/S1PR3 signaling mediated proliferation of pericytes via Ras/pERK pathway and CAY10444 had beneficial effects on spinal cord injury. 2018 Biochem. Biophys. Res. Commun. pmid:29534963
Yu FC et al. Protective effect of sphingosine-1-phosphate for chronic intermittent hypoxia-induced endothelial cell injury. 2018 Biochem. Biophys. Res. Commun. pmid:29550481
Nádró B et al. [The role of apolipoprotein M and sphingosine 1-phosphate axis in the prevention of atherosclerosis]. 2018 Orv Hetil pmid:29376427
Deshpande GP et al. Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF). 2018 Life Sci. pmid:29373815
Książek M et al. Arteriovenous Sphingosine-1-Phosphate Differences Across Selected Organs of the Rat. 2018 Cell. Physiol. Biochem. pmid:29316552
Huang Y et al. S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. 2018 Science pmid:29302015
Ahn EH et al. Sphingosine Induces Apoptosis and Down-regulation of in PAX3-FOXO1-positive Alveolar Rhabdomyosarcoma Cells Irrespective of Mutation. 2018 Anticancer Res. pmid:29277758
Zhang YL et al. Non-invasive assessment of culture media from goat cloned embryos associated with subjective morphology by gas chromatography - mass spectroscopy-based metabolomic analysis. 2018 Anim. Sci. J. pmid:28833899
Zheng Y et al. A Sphingosine-type cerebroside in Clavicorona pyxidata induce fruit body formation. 2018 Nat. Prod. Res. pmid:28347179
Ogretmen B Sphingolipid metabolism in cancer signalling and therapy. 2018 Nat. Rev. Cancer pmid:29147025