sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Hsia K et al. Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. 2017 Acta Biomater pmid:28110073
Maiti A et al. Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival. 2017 Cell. Signal. pmid:28108260
Meissner A et al. Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension. 2017 Cardiovasc. Res. pmid:28082452
Ruiz M et al. High-Density Lipoprotein-Associated Apolipoprotein M Limits Endothelial Inflammation by Delivering Sphingosine-1-Phosphate to the Sphingosine-1-Phosphate Receptor 1. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:27879252
Barnawi J et al. Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. 2017 Respirology pmid:27868302
Frias MA et al. High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. 2017 Eur. J. Clin. Invest. pmid:27861771
Fang V et al. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. 2017 Nat. Immunol. pmid:27841869
Wang R et al. Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. 2017 Am. J. Pathol. pmid:27840081
Engel N et al. Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-Regulation. 2017 PLoS ONE pmid:28125641
Pal SK et al. A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. 2017 Cancer pmid:27727447
Lim J et al. Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells. 2017 Int. J. Mol. Med. pmid:28677769
Pierucci F et al. Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. 2017 Arch. Toxicol. pmid:27318803
Doan NB et al. Acid ceramidase confers radioresistance to glioblastoma cells. 2017 Oncol. Rep. pmid:28765947
Arish M et al. Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies. 2017 J. Recept. Signal Transduct. Res. pmid:28758826
Song L et al. Urine Metabonomics Reveals Early Biomarkers in Diabetic Cognitive Dysfunction. 2017 J. Proteome Res. pmid:28722418
Polzin A et al. Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease. 2017 J. Mol. Cell. Cardiol. pmid:28709768
Innamorati G et al. Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. 2017 Cell Death Dis pmid:28703804
Bougault C et al. Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. 2017 Bone pmid:28684192
Tsai CH et al. Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. 2017 Mol Oncol pmid:28672103
Xie Z et al. Targeting sphingosine-1-phosphate signaling for cancer therapy. 2017 Sci China Life Sci pmid:28623546
Yanagida K et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28396408
Wilkerson JL and Mandal NA Angiogenesis Model of Cornea to Understand the Role of Sphingosine 1-Phosphate. 2017 Methods Mol. Biol. pmid:28660590
Trautz B et al. The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles. 2017 J. Biol. Chem. pmid:28659343
Školová B et al. Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics. 2017 Biochim. Biophys. Acta pmid:28109750
Calderón R et al. Stereoselective preparation of quaternary 2-vinyl sphingosines and ceramides and their effect on basal sphingolipid metabolism. 2017 Chem. Phys. Lipids pmid:28445710
Lafargue A et al. Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation. 2017 Free Radic. Biol. Med. pmid:28431961
Ohno H et al. Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure-activity relationship study of 4-epi-jaspine B. 2017 Bioorg. Med. Chem. pmid:28408190
Jang EJ et al. Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway. 2017 J. Dermatol. Sci. pmid:28390782
Yu M et al. The Effect of Chinese Herbal Medicine Formula mKG on Allergic Asthma by Regulating Lung and Plasma Metabolic Alternations. 2017 Int J Mol Sci pmid:28287417
Fan C et al. Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells. 2017 Neurosci. Lett. pmid:28288862
Li S et al. Sphingosine-1-phosphate activates the AKT pathway to inhibit chemotherapy induced human granulosa cell apoptosis. 2017 Gynecol. Endocrinol. pmid:28277139
Garnero P The Utility of Biomarkers in Osteoporosis Management. 2017 Mol Diagn Ther pmid:28271451
Ebenezer DL et al. Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. 2017 Adv Biol Regul pmid:27720306
Barbour M et al. Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis. 2017 Br. J. Pharmacol. pmid:27864936
Shao C et al. Detection of Urine Metabolites in a Rat Model of Chronic Fatigue Syndrome before and after Exercise. 2017 Biomed Res Int pmid:28421200
Thieme M et al. Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. 2017 Exp. Dermatol. pmid:27574180
Jang Y et al. Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. 2017 J. Nutr. Biochem. pmid:28456081
Hutami IR et al. Fas/S1P crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. 2017 Biochem. Biophys. Res. Commun. pmid:28687489
Cannavo A et al. β-Blockade Prevents Post-Ischemic Myocardial Decompensation Via βAR-Dependent Protective Sphingosine-1 Phosphate Signaling. 2017 J. Am. Coll. Cardiol. pmid:28683966
Punsawad C and Viriyavejakul P Reduction in serum sphingosine 1-phosphate concentration in malaria. 2017 PLoS ONE pmid:28666023
Luo J et al. The effects of berberine on a murine model of multiple sclerosis and the SPHK1/S1P signaling pathway. 2017 Biochem. Biophys. Res. Commun. pmid:28655617
Chang CH and Randolph GJ Sphingosine-1-Phosphate as the Lymphocyte's Ticket to Ride and Survive. 2017 Dev. Cell pmid:28633013
Aoyama-Araki Y et al. Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. 2017 Invest. Ophthalmol. Vis. Sci. pmid:28418499
Frej C et al. A Shift in ApoM/S1P Between HDL-Particles in Women With Type 1 Diabetes Mellitus Is Associated With Impaired Anti-Inflammatory Effects of the ApoM/S1P Complex. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:28385702
Nakajima M et al. The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. 2017 Tumour Biol. pmid:28381169
Nielsen OH et al. Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease. 2017 Trends Mol Med pmid:28283249
Peyrin-Biroulet L et al. Modulation of sphingosine-1-phosphate in inflammatory bowel disease. 2017 Autoimmun Rev pmid:28279838
Miller M et al. Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. 2017 J. Immunol. pmid:28275141
Alvares DS et al. Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide. 2017 Biochim. Biophys. Acta pmid:28274844
Jadhav S et al. Inositol Depletion Induced by Acute Treatment of the Bipolar Disorder Drug Valproate Increases Levels of Phytosphingosine. 2017 J. Biol. Chem. pmid:28100786
Vishwakarma S et al. Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. 2017 Cancer Invest. pmid:28135860
Kurano M et al. Involvement of CETP (Cholesteryl Ester Transfer Protein) in the Shift of Sphingosine-1-Phosphate Among Lipoproteins and in the Modulation of its Functions. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:28126827
Wang Y et al. The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. 2017 Hepatology pmid:28120434
Tang HB et al. S1P/S1PR3 signaling mediated proliferation of pericytes via Ras/pERK pathway and CAY10444 had beneficial effects on spinal cord injury. 2018 Biochem. Biophys. Res. Commun. pmid:29534963
Yu FC et al. Protective effect of sphingosine-1-phosphate for chronic intermittent hypoxia-induced endothelial cell injury. 2018 Biochem. Biophys. Res. Commun. pmid:29550481
Nádró B et al. [The role of apolipoprotein M and sphingosine 1-phosphate axis in the prevention of atherosclerosis]. 2018 Orv Hetil pmid:29376427
Deshpande GP et al. Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF). 2018 Life Sci. pmid:29373815
Książek M et al. Arteriovenous Sphingosine-1-Phosphate Differences Across Selected Organs of the Rat. 2018 Cell. Physiol. Biochem. pmid:29316552
Huang Y et al. S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. 2018 Science pmid:29302015
Ahn EH et al. Sphingosine Induces Apoptosis and Down-regulation of in PAX3-FOXO1-positive Alveolar Rhabdomyosarcoma Cells Irrespective of Mutation. 2018 Anticancer Res. pmid:29277758
Zhang YL et al. Non-invasive assessment of culture media from goat cloned embryos associated with subjective morphology by gas chromatography - mass spectroscopy-based metabolomic analysis. 2018 Anim. Sci. J. pmid:28833899
Zheng Y et al. A Sphingosine-type cerebroside in Clavicorona pyxidata induce fruit body formation. 2018 Nat. Prod. Res. pmid:28347179
Ogretmen B Sphingolipid metabolism in cancer signalling and therapy. 2018 Nat. Rev. Cancer pmid:29147025