sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Patton JL et al. Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiae. 1992 J. Bacteriol. pmid:1429441
Pradines-Figueres A and Raetz CR Processing and secretion of tumor necrosis factor alpha in endotoxin-treated Mono Mac 6 cells are dependent on phorbol myristate acetate. 1992 J. Biol. Chem. pmid:1429672
Downey GP et al. Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C. 1992 J. Cell Biol. pmid:1370499
Wei LL et al. Alkaline phosphatase activity during differentiation of the human promyelocytic leukemia cell line, HL-60. 1992 Biochem. Biophys. Res. Commun. pmid:1734863
Johnson JE et al. Comparison of the lipid regulation of yeast and rat CTP: phosphocholine cytidylyltransferase expressed in COS cells. 1992 Biochem. J. pmid:1323275
Kiss Z and Deli E Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts. 1992 Biochem. J. pmid:1472000
Sandler N and Keynan A Membrane-protein phosphorylation in the Bacillus subtilis cell cycle. 1992 FEMS Microbiol. Lett. pmid:1526457
Wang E et al. Increases in serum sphingosine and sphinganine and decreases in complex sphingolipids in ponies given feed containing fumonisins, mycotoxins produced by Fusarium moniliforme. 1992 J. Nutr. pmid:1640265
Goldin E et al. Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver. 1992 Biochim. Biophys. Acta pmid:1324734
Uhrig ML et al. Metabolic labelling and partial characterisation of a sulfoglycolipid in Trypanosoma cruzi trypomastigotes. 1992 Carbohydr. Res. pmid:1394325
Wakita H et al. Composition of free long-chain (sphingoid) bases in stratum corneum of normal and pathologic human skin conditions. 1992 J. Invest. Dermatol. pmid:1431224
Rother J et al. Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells. 1992 Biochem. Biophys. Res. Commun. pmid:1449467
Olivera A et al. Sphingomyelinase and cell-permeable ceramide analogs stimulate cellular proliferation in quiescent Swiss 3T3 fibroblasts. 1992 J. Biol. Chem. pmid:1464623
Abe A et al. Metabolic effects of short-chain ceramide and glucosylceramide on sphingolipids and protein kinase C. 1992 Eur. J. Biochem. pmid:1483461
Scheidl H et al. The effect of sphingosine and phorbol ester on the signal transduction enzymes and fibronectin release in cell culture. 1992 Biochim. Biophys. Acta pmid:1377951
Murray MA et al. Effect of protein kinase C inhibitors on endothelin- and vasopressin-induced constriction of the rat basilar artery. 1992 Am. J. Physiol. pmid:1481891
Considine RV et al. Role of protein kinase C in short-term transmission at the mammalian neuromuscular junction. 1992 J. Pharmacol. Exp. Ther. pmid:1335062
Mäkelä JH and Isomaa B Sphingosine induced release of K+ and 5-HT in platelets should not be confused with membrane leakiness. 1992 Chem. Biol. Interact. pmid:1458549
Abdel-Ghany M et al. Substrate-specific modulation of Src-mediated phosphorylation of Ras and caseins by sphingosines and other substrate modulators. 1992 Biochim. Biophys. Acta pmid:1280164
Wadman WJ and Connor JA Persisting modification of dendritic calcium influx by excitatory amino acid stimulation in isolated Ca1 neurons. 1992 Neuroscience pmid:1351266
Sabbadini RA et al. The effects of sphingosine on sarcoplasmic reticulum membrane calcium release. 1992 J. Biol. Chem. pmid:1386359
Franson RC et al. Sphingolipid metabolism and signal transduction: inhibition of in vitro phospholipase activity by sphingosine. 1992 Biochim. Biophys. Acta pmid:1504102
Takahashi M et al. Phosphorylated cystatin alpha is a natural substrate of epidermal transglutaminase for formation of skin cornified envelope. 1992 FEBS Lett. pmid:1353732
Pushkareva MYu WA et al. Sphingosine activation of protein kinases in Jurkat T cells. In vitro phosphorylation of endogenous protein substrates and specificity of action. 1992 J. Biol. Chem. pmid:1634554
Gomez-Muñoz A et al. Effects of sphingosine, albumin and unsaturated fatty acids on the activation and translocation of phosphatidate phosphohydrolases in rat hepatocytes. 1992 Biochim. Biophys. Acta pmid:1320939
Tanabe S et al. Sphingosine inhibits factor Xa-catalyzed prothrombin activation on the surface of cultured calf pulmonary artery endothelium perturbed by hydrogen peroxide. 1992 Thromb. Res. pmid:1440510
Buehrer BM and Bell RM Inhibition of sphingosine kinase in vitro and in platelets. Implications for signal transduction pathways. 1992 J. Biol. Chem. pmid:1310683
Singh IN et al. Oleoylamine and sphingosine stimulation of phosphatidylserine synthesis by LA-N-2 cells is protein kinase C independent. 1992 FEBS Lett. pmid:1733773
Boekhoff I and Breer H Termination of second messenger signaling in olfaction. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1370581
Merrill AH and Wang E Enzymes of ceramide biosynthesis. 1992 Meth. Enzymol. pmid:1495423
Wieland F Transfer of bulk markers from endoplasmic reticulum to plasma membrane. 1992 Meth. Enzymol. pmid:1487992
Desai NN et al. Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation. 1992 J. Biol. Chem. pmid:1429659
Murray MA et al. Role of protein kinase C in constrictor responses of the rat basilar artery in vivo. 1992 J. Physiol. (Lond.) pmid:1501132
Chao R et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. 1992 J. Biol. Chem. pmid:1385423
Kachintorn U et al. Dual effects of a phorbol ester on calcium-dependent chloride secretion by T84 epithelial cells. 1992 Am. J. Physiol. pmid:1733229
Ritchie T et al. Regulation of phosphoinositide hydrolysis in cultured astrocytes by sphingosine and psychosine. 1992 Biochem. Biophys. Res. Commun. pmid:1323292
Yung BY et al. Interaction of antileukemia agents adriamycin and daunomycin with sphinganine on the differentiation of human leukemia cell line HL-60. 1992 Cancer Res. pmid:1617630
Bertorello AM Diacylglycerol activation of protein kinase C results in a dual effect on Na+,K(+)-ATPase activity from intact renal proximal tubule cells. 1992 J. Cell. Sci. pmid:1321161
Perillo MA et al. Molecular parameters of semisynthetic derivatives of gangliosides and sphingosine in monolayers at the air-water interface. 1993 Chem. Phys. Lipids pmid:8269552
Torossian K et al. Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation. 1993 Biochem. J. pmid:8382476
Hansen AB et al. Role of protein kinase C during interferon-gamma- and phorbol ester-stimulated immunocytochemical expression of ICAM-1 in human renal carcinoma cells. 1993 APMIS pmid:8103344
Crow T and Forrester J Down-regulation of protein kinase C and kinase inhibitors dissociate short- and long-term enhancement produced by one-trial conditioning of Hermissenda. 1993 J. Neurophysiol. pmid:8459291
Kinnunen PK et al. Sphingosine-mediated membrane association of DNA and its reversal by phosphatidic acid. 1993 Chem. Phys. Lipids pmid:7509731
Kim HS et al. Sphingosine blocks both membrane fusion and calmodulin-dependent phosphorylation of the 100-kDa protein of chick embryonic myoblasts. 1993 Exp. Cell Res. pmid:8482346
Desai NN et al. Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts. 1993 J. Cell Biol. pmid:8389770
López-García F et al. Interaction of sphingosine and stearylamine with phosphatidylserine as studied by DSC and NMR. 1993 Biochim. Biophys. Acta pmid:8241241
Paige DG et al. The quantification of free sphingosine in the stratum corneum of patients with hereditary ichthyosis. 1993 Br. J. Dermatol. pmid:8217748
Yung BY and Hui EK Differential regulation of protein kinase C isoenzymes during sphinganine potentiation of retinoic acid-induced granulocytic differentiation in human leukemia HL-60 cells. 1993 Biochem. Biophys. Res. Commun. pmid:8250895
Alexandrova AY et al. Motility of intracellular particles in rat fibroblasts is greatly enhanced by phorbol ester and by over-expression of normal p21N-ras. 1993 Cell Motil. Cytoskeleton pmid:8221903
Pushkareva MYu A et al. Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid bases and inhibition by non-esterified fatty acids. 1993 Biochem. J. pmid:8379926
Wu WI et al. Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases. 1993 J. Biol. Chem. pmid:8314751
Yamada K et al. Sphingosine activates cellular diacylglycerol kinase in intact Jurkat cells, a human T-cell line. 1993 Biochim. Biophys. Acta pmid:7548113
Thomas DJ et al. Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate. 1993 Metab. Clin. Exp. pmid:8387623
Yamada K and Sakane F The different effects of sphingosine on diacylglycerol kinase isozymes in Jurkat cells, a human T-cell line. 1993 Biochim. Biophys. Acta pmid:7548112
Ladenson RC et al. Utilization of exogenously supplied sphingosine analogues for sphingolipid biosynthesis in Chinese hamster ovary and mouse LM cell fibroblasts. 1993 J. Biol. Chem. pmid:8463295
Maiese K et al. Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia. 1993 J. Neurosci. Res. pmid:8230323
Sitges M and Talamo BR Sphingosine, W-7, and trifluoperazine inhibit the elevation in cytosolic calcium induced by high K+ depolarization in synaptosomes. 1993 J. Neurochem. pmid:8336133
David MJ et al. Characterization of gangliosides from normal and osteoarthritic human articular cartilage. 1993 Arthritis Rheum. pmid:8318040
Hirschberg K et al. The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver. 1993 Biochem. J. pmid:8457204
Sabbadini R et al. Sphingosine is endogenous to cardiac and skeletal muscle. 1993 Biochem. Biophys. Res. Commun. pmid:8512573
Olivera A and Spiegel S Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. 1993 Nature pmid:8413613
Yule DI et al. Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells. 1993 J. Biol. Chem. pmid:8509375
Crow T and Forrester J Protein kinase inhibitors do not block the expression of established enhancement in identified Hermissenda B-photoreceptors. 1993 Brain Res. pmid:8348304
Katoh N Modulation by sphingosine of substrate phosphorylation by protein kinase C in bovine mammary gland. 1993 Lipids pmid:8246685
Soares-da-Silva P Enhanced protein kinase C mediated inhibition of renal dopamine synthesis during high sodium intake. 1993 Biochem. Pharmacol. pmid:8494538
Stewart SJ et al. Activation of phospholipase D following perturbation of the human T lymphocyte antigen receptor/CD3 complex is dependent upon protein kinase C. 1993 Cell. Signal. pmid:8347422
Ogawa A et al. Na+/H+ exchange activity induced by thrombin is not inhibited by protein kinase inhibitors, staurosporine, K-252a, H-7 and sphingosine, in human platelets. 1993 Thromb. Res. pmid:8391729
Kanfer JN and McCartney DG Modulation of the serine base exchange enzyme activity of rat brain membranes by amphiphilic cations and amphiphilic anions. 1993 J. Neurochem. pmid:8455023
Mäkelä JH and Isomaa B Perturbation of the platelet plasma membrane is not sufficient for inhibition of thrombin-induced PKC-activity. 1993 Chem. Biol. Interact. pmid:8485783
Archibald DD and Mann S Structural studies of lipid fibers formed by sphingosine. 1993 Biochim. Biophys. Acta pmid:8443231
Pinkerton FD et al. D-erythro-sphingosine lowers 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Chinese hamster ovary cells. 1993 Biochem. Biophys. Res. Commun. pmid:8422261
Hayashi K and Niwayama S Effects of gangliosides on the growth of herpes simplex virus type 1-infected cells derived from neurons and on viral replication. 1993 Intervirology pmid:8150594
Jacobs LS and Kester M Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells. 1993 Am. J. Physiol. pmid:8214030
Sugiyama E et al. Metabolism and neurite promoting effect of exogenous sphingosylphosphocholine in cultured murine neuroblastoma cells. 1993 J. Biochem. pmid:8514735
Riboni L et al. Metabolism of exogenous ganglioside GM1 in cultured cerebellar granule cells. The fatty acid and sphingosine moieties formed during degradation are re-used for lipid biosynthesis. 1993 FEBS Lett. pmid:8486159
Uemura K et al. Inhibition of neurite outgrowth in neuroblastoma cells by sphingosine. 1993 J. Biochem. pmid:8276777
Härmälä AS et al. Sphingosine inhibits sphingomyelinase-induced cholesteryl ester formation in cultured fibroblasts. 1993 Biochim. Biophys. Acta pmid:8257725
Riley RT et al. Alteration of tissue and serum sphinganine to sphingosine ratio: an early biomarker of exposure to fumonisin-containing feeds in pigs. 1993 Toxicol. Appl. Pharmacol. pmid:8430417
Downing DT et al. Interaction between sphingosine and cholesteryl sulfate in epidermal lipids. 1993 J. Lipid Res. pmid:8496662
Pahlavan P et al. Role of protein kinase C in the adaptive increase in Na-H antiporter in respiratory acidosis. 1993 J. Am. Soc. Nephrol. pmid:8286716
Wong K and Kwan-Yeung L Sphingosine mobilizes intracellular calcium in human neutrophils. 1993 Cell Calcium pmid:8358772
Sanguedolce MV et al. Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C. 1993 J. Immunol. pmid:7686943
Zoukhri D et al. Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector. 1993 Am. J. Physiol. pmid:8386449
Soares-da-Silva P Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists. 1993 Br. J. Pharmacol. pmid:8102930
Bayat-Sarmadi M and Houdebine LM Effect of various protein kinase inhibitors on the induction of milk protein gene expression by prolactin. 1993 Mol. Cell. Endocrinol. pmid:8472863
Hui EK and Yung BY Cell cycle phase-dependent effect of retinoic acid on the induction of granulocytic differentiation in HL-60 promyelocytic leukemia cells. Evidence for sphinganine potentiation of retinoic acid-induced differentiation. 1993 FEBS Lett. pmid:7680007
Durieux ME et al. Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling. 1993 Am. J. Physiol. pmid:7684565
Reston JT et al. Differential effects of the phorbol ester TPA on DNA-mediated transfection in a variety of cell lines. 1993 Biochim. Biophys. Acta pmid:8485168
Mangin EL et al. Effects of lysolipids and oxidatively modified low density lipoprotein on endothelium-dependent relaxation of rabbit aorta. 1993 Circ. Res. pmid:8417838
Clarke BL et al. Regulation of parathyroid hormone release by protein kinase-C is dependent on extracellular calcium in bovine parathyroid cells. 1993 Endocrinology pmid:8440177
Burgers JA and Akkerman JW Regulation of the receptor for platelet-activating factor on human platelets. 1993 Biochem. J. pmid:8385926
Schneider JS and DiStefano L LIGA 20 increases striatal dopamine levels in aged MPTP-treated mice refractory to GM1 ganglioside treatment. 1993 Neuroreport pmid:8110995
Kõiv A et al. Influence of sphingosine on the thermal phase behaviour of neutral and acidic phospholipid liposomes. 1993 Chem. Phys. Lipids pmid:8118913
Merrill AH et al. Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. 1993 J. Biol. Chem. pmid:8262970
Skaper SD et al. A semisynthetic glycosphingolipid (LIGA20) reduces 2,4, 5-trihydroxyphenylalanine neurotoxicity in primary neuronal cultures. 1993 Eur. J. Pharmacol. pmid:8253129
Zhao C et al. Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. 1994 J. Biol. Chem. pmid:8063782
Hudson PL et al. Modulation by sphingolipids of calcium signals evoked by epidermal growth factor. 1994 J. Biol. Chem. pmid:8063833
Ricciolini R et al. Dexamethasone-dependent modulation of human lymphoblastoid B cell line through sphingosine production. 1994 Biochim. Biophys. Acta pmid:8148386
Yamaguchi Y et al. The synthetic pathway for glucosylsphingosine in cultured fibroblasts. 1994 J. Biochem. pmid:7852294
Miccheli A et al. Dexamethasone-dependent modulation of cholesterol levels in human lymphoblastoid B cell line through sphingosine production. 1994 Biochim. Biophys. Acta pmid:8148395