| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ouairy CM et al. | Development of an acid ceramidase activity-based probe. | 2015 | Chem. Commun. (Camb.) | pmid:25748248 |
| Desai P et al. | Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. | 2015 | Mol. Cell. Biochem. | pmid:26350564 |
| Wilson PC et al. | Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. | 2015 | Mol. Endocrinol. | pmid:25871850 |
| Jernigan PL et al. | The role of sphingolipids in endothelial barrier function. | 2015 | Biol. Chem. | pmid:25867999 |
| Egom EE et al. | The effect of the sphingosine-1-phosphate analogue FTY720 on atrioventricular nodal tissue. | 2015 | J. Cell. Mol. Med. | pmid:25864579 |
| Ohkawa R et al. | Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. | 2015 | Clin. Biochem. | pmid:25863111 |
| Radue EW et al. | Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. | 2015 | Neurology | pmid:25632085 |
| Wang L et al. | Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate. | 2015 | Microvasc. Res. | pmid:25862132 |
| Signoriello E et al. | Fingolimod efficacy in multiple sclerosis associated with Sjogren syndrome. | 2015 | Acta Neurol. Scand. | pmid:25622658 |
| Kolahdooz Z et al. | Sphingosin-1-phosphate Receptor 1: a Potential Target to Inhibit Neuroinflammation and Restore the Sphingosin-1-phosphate Metabolism. | 2015 | Can J Neurol Sci | pmid:25860537 |
| Wu JX et al. | The Arabidopsis ceramidase AtACER functions in disease resistance and salt tolerance. | 2015 | Plant J. | pmid:25619405 |
| Ren K et al. | Apolipoprotein M. | 2015 | Clin. Chim. Acta | pmid:25858547 |
| Martinková M et al. | Total synthesis of pachastrissamine together with its 4-epi-congener via [3,3]-sigmatropic rearrangements and antiproliferative/cytotoxic evaluation. | 2015 | Carbohydr. Res. | pmid:25486219 |
| Moolenaar WH | Introduction to the ECR special issue on lysophospholipids in biology. | 2015 | Exp. Cell Res. | pmid:25746723 |
| Muñoz-Sáez E et al. | Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y). | 2015 | Neurosci. Lett. | pmid:25769802 |
| Abdel Hadi L et al. | Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells. | 2015 | PLoS ONE | pmid:26580959 |
| Kang H et al. | The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. | 2015 | Stem Cells Dev. | pmid:25761906 |
| Carrera I et al. | A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. | 2015 | Biomed Res Int | pmid:25759822 |
| Ueda N | Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. | 2015 | Int J Mol Sci | pmid:25751724 |
| Zhao S and Li J | Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. | 2015 | PLoS ONE | pmid:25748447 |
| Issa NP and Hentati A | VZV encephalitis that developed in an immunized patient during fingolimod therapy. | 2015 | Neurology | pmid:25416038 |
| Lin CC et al. | Sphingosine-1-phosphate mediates ICAM-1-dependent monocyte adhesion through p38 MAPK and p42/p44 MAPK-dependent Akt activation. | 2015 | PLoS ONE | pmid:25734900 |
| Zhang DD et al. | Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors. | 2015 | Biol. Chem. | pmid:25720064 |
| Cozza G et al. | A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. | 2015 | Biochim. Biophys. Acta | pmid:25936777 |
| Zhong Y et al. | Nephrokeli, a Chinese herbal formula, may improve IgA nephropathy through regulation of the sphingosine-1-phosphate pathway. | 2015 | PLoS ONE | pmid:25633986 |
| Till KJ et al. | Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells. | 2015 | J. Immunol. | pmid:25632006 |
| Liu M et al. | Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles. | 2015 | J. Biol. Chem. | pmid:25627684 |
| Hwang IY et al. | An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking. | 2015 | J. Immunol. | pmid:25617475 |
| Mikłosz A et al. | Hyperthyroidism evokes myocardial ceramide accumulation. | 2015 | Cell. Physiol. Biochem. | pmid:25613909 |
| Othman A et al. | Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats. | 2015 | Diabetes | pmid:25277395 |
| O'Sullivan C and Dev KK | Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. | 2015 | J. Cell. Sci. | pmid:26359302 |
| Duan J and Merrill AH | 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma. | 2015 | J. Biol. Chem. | pmid:25947379 |
| Slowik A et al. | The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. | 2015 | Br. J. Pharmacol. | pmid:25220526 |
| Kurano M et al. | LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. | 2015 | J. Biol. Chem. | pmid:25505264 |
| Konstantinou D et al. | Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. | 2015 | Cell Biol. Int. | pmid:25492631 |
| Pyne NJ and Kolesnick RN | The life and work of Dr. Robert Bittman (1942-2014). | 2015 | Biol. Chem. | pmid:25473803 |
| Frati A et al. | Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxin. | 2015 | Mol. Endocrinol. | pmid:25415609 |
| Chawla S and Saxena S | Differential modulation of S1PR(1-5) and specific activities of SphK and nSMase in pulmonary and cerebral tissues of rats exposed to hypobaric hypoxia. | 2015 | Lipids | pmid:25398597 |
| Santos WL and Lynch KR | Drugging sphingosine kinases. | 2015 | ACS Chem. Biol. | pmid:25384187 |
| Jaramillo-Gómez J et al. | Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy. | 2015 | Neurosci. Lett. | pmid:26222260 |
| Landi D et al. | Oral fingolimod reduces glutamate-mediated intracortical excitability in relapsing-remitting multiple sclerosis. | 2015 | Clin Neurophysiol | pmid:25022794 |
| Mani R et al. | Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia. | 2015 | Leukemia | pmid:24947019 |
| Klocke S et al. | Slow-freezing versus vitrification for human ovarian tissue cryopreservation. | 2015 | Arch. Gynecol. Obstet. | pmid:25115279 |
| Wysoczynski M et al. | Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells. | 2015 | Stem Cell Rev | pmid:25086571 |
| Cukkemane N et al. | Anti-adherence and bactericidal activity of sphingolipids against Streptococcus mutans. | 2015 | Eur. J. Oral Sci. | pmid:26094809 |
| Burow P et al. | Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. | 2015 | Pflugers Arch. | pmid:24965069 |
| Hahn I et al. | Effects of orally administered fumonisin Bâ‚ (FBâ‚), partially hydrolysed FBâ‚, hydrolysed FBâ‚ and N-(1-deoxy-D-fructos-1-yl) FBâ‚ on the sphingolipid metabolism in rats. | 2015 | Food Chem. Toxicol. | pmid:25475052 |
| Siow D et al. | Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. | 2015 | Adv Biol Regul | pmid:25319495 |
| Valentijn-Benz M et al. | Sphingoid bases inhibit acid-induced demineralization of hydroxyapatite. | 2015 | Caries Res. | pmid:25300299 |
| Oskeritzian CA | Mast cell plasticity and sphingosine-1-phosphate in immunity, inflammation and cancer. | 2015 | Mol. Immunol. | pmid:24766823 |
| Iwabuchi K et al. | Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. | 2015 | Mediators Inflamm. | pmid:26609196 |
| Mahajan-Thakur S et al. | Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation. | 2015 | Mediators Inflamm. | pmid:26604433 |
| Barnawi J et al. | Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). | 2015 | PLoS ONE | pmid:26485657 |
| Moruno Manchon JF et al. | Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. | 2015 | Sci Rep | pmid:26477494 |
| Wang K et al. | Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. | 2015 | PLoS Genet. | pmid:26474409 |
| Jeong JK et al. | Modulation of the expression of sphingosine 1-phosphate 2 receptors regulates the differentiation of pre-adipocytes. | 2015 | Mol Med Rep | pmid:26459774 |
| Johnson CH et al. | Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. | 2015 | J Neuroimmune Pharmacol | pmid:26232265 |
| Sutter I et al. | Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL. | 2015 | Atherosclerosis | pmid:26093887 |
| Zhang SQ et al. | Mutation of G234 amino acid residue in candida albicans drug-resistance-related protein Rta2p is associated with fluconazole resistance and dihydrosphingosine transport. | 2015 | Virulence | pmid:26220356 |
| Kihara Y et al. | Lysophospholipid receptors in drug discovery. | 2015 | Exp. Cell Res. | pmid:25499971 |
| Grenier B et al. | Dose-dependent effects on sphingoid bases and cytokines in chickens fed diets prepared with fusarium verticillioides culture material containing fumonisins. | 2015 | Toxins (Basel) | pmid:25871822 |
| Choi S et al. | A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26361873 |
| Le Bihan O et al. | Visualization of adherent cell monolayers by cryo-electron microscopy: A snapshot of endothelial adherens junctions. | 2015 | J. Struct. Biol. | pmid:26470813 |
| Flávia Nardy A et al. | Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease. | 2015 | Biomed Res Int | pmid:26347020 |
| Dai L et al. | Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression. | 2015 | Oncotarget | pmid:26327294 |
| Simón MV et al. | Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. | 2015 | Invest. Ophthalmol. Vis. Sci. | pmid:26325420 |
| Yang L et al. | Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice. | 2015 | Sci Rep | pmid:26324256 |
| Hsu CK et al. | Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. | 2015 | Br. J. Pharmacol. | pmid:26359950 |
| Höglinger D et al. | Intracellular sphingosine releases calcium from lysosomes. | 2015 | Elife | pmid:26613410 |
| Brinkman CC and Bromberg JS | Biological sensors shed light on ligand geography. | 2015 | Nat. Immunol. | pmid:26580500 |
| Wisse P et al. | Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy. | 2015 | J. Org. Chem. | pmid:26061009 |
| Yester JW et al. | Sphingosine-1-phosphate inhibits IL-1-induced expression of C-C motif ligand 5 via c-Fos-dependent suppression of IFN-β amplification loop. | 2015 | FASEB J. | pmid:26246404 |
| Renaud JB et al. | Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26467225 |
| Kharel Y et al. | Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. | 2015 | J. Pharmacol. Exp. Ther. | pmid:26243740 |
| Gao XY et al. | Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. | 2015 | Oncol. Rep. | pmid:26239167 |
| Adada MM et al. | Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion. | 2015 | FASEB J. | pmid:26209696 |
| Dabkowska AP et al. | Assembly of RNA nanostructures on supported lipid bilayers. | 2015 | Nanoscale | pmid:25417592 |
| Wang H et al. | Sphingosine-1-Phosphate Induces the Migration and Angiogenesis of Epcs Through the Akt Signaling Pathway via Sphingosine-1-Phosphate Receptor 3/Platelet-Derived Growth Factor Receptor-β. | 2015 | Cell. Mol. Biol. Lett. | pmid:26208383 |
| Malinina L and Brown RE | Catalytic Mechanism of Eukaryotic Neutral Ceramidase. | 2015 | Structure | pmid:26244839 |
| Janssen S et al. | Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro. | 2015 | Mol Med Rep | pmid:26239526 |
| Giese AK et al. | A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease. | 2015 | Orphanet J Rare Dis | pmid:26082315 |
| Absher JR | ACP Journal Club. In multiple sclerosis, use of fingolimod reduced immune responses to influenza and tetanus booster vaccines. | 2015 | Ann. Intern. Med. | pmid:26075785 |
| Han SH et al. | Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells. | 2015 | BMB Rep | pmid:26077028 |
| Chen MH et al. | Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. | 2015 | Oncotarget | pmid:26090720 |
| Panneer Selvam S et al. | Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. | 2015 | Sci Signal | pmid:26082434 |
| Malik FA et al. | Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. | 2015 | PLoS ONE | pmid:26079370 |
| Mooren OL et al. | Role of N-WASP in Endothelial Monolayer Formation and Integrity. | 2015 | J. Biol. Chem. | pmid:26070569 |
| Pfender N et al. | Reactivation of herpesvirus under fingolimod: A case of severe herpes simplex encephalitis. | 2015 | Neurology | pmid:25957334 |
| Zhang L et al. | FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. | 2015 | Toxicol. Lett. | pmid:25939952 |
| Mani R et al. | ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo. | 2015 | Exp. Hematol. | pmid:25937048 |
| Zonta F et al. | Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. | 2015 | Blood | pmid:25931585 |
| El-Najjar N et al. | Increased Levels of Sphingosylphosphorylcholine (SPC) in Plasma of Metabolic Syndrome Patients. | 2015 | PLoS ONE | pmid:26466367 |
| Shirao S et al. | A novel trigger for cholesterol-dependent smooth muscle contraction mediated by the sphingosylphosphorylcholine-Rho-kinase pathway in the rat basilar artery: a mechanistic role for lipid rafts. | 2015 | J. Cereb. Blood Flow Metab. | pmid:25605290 |
| Shih HJ et al. | FTY720 mitigates torsion/detorsion-induced testicular injury in rats. | 2015 | J. Surg. Res. | pmid:25862489 |
| Mori M | Lethal arrhythmia due to fingolimod, a S1P receptor modulator: are we overestimating or underestimating? | 2015 | J. Neurol. Neurosurg. Psychiatry | pmid:25855398 |
| Laurenzana A et al. | Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts. | 2015 | J. Mol. Med. | pmid:25952146 |
| Rahman MM et al. | Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs. | 2015 | Biochem. Biophys. Res. Commun. | pmid:25951977 |
| Prager B et al. | Sphingosine 1-phosphate signaling at the blood-brain barrier. | 2015 | Trends Mol Med | pmid:25939882 |
| Rosenberg AJ et al. | A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. | 2015 | Appl Radiat Isot | pmid:25931137 |
| Sobel K et al. | FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction. | 2015 | Mol. Pharmacol. | pmid:25762025 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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