sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Taki T et al. A ganglioside of rat ascites hepatoma AH 7974F cells. Occurrence of a novel disialoganglioside (GD1 alpha) with a unique N-acetylneuraminosyl (alpha 2-6)-N-acetylgalactosamine structure. 1986 J. Biol. Chem. pmid:3949760
Merrill AH et al. Differences in the long chain (sphingoid) base composition of sphingomyelin from rats bearing Morris hepatoma 7777. 1986 Lipids pmid:3762323
Hannun YA et al. Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways. 1987 J. Biol. Chem. pmid:3115982
Nutter LM et al. Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. 1987 Cancer Res. pmid:3038311
Yasugi E et al. Branched long chain bases in cerebrosides of the guinea pig Harderian gland. 1987 J. Biochem. pmid:3448092
Bouchon B et al. Selective enrichment of phytosphingosine in glycosphingolipids of isolated human thyrocytes as compared to the whole thyroid. 1987 Biochem. Biophys. Res. Commun. pmid:3566758
Pittet D et al. Nonselective inhibition of neutrophil functions by sphinganine. 1987 J. Biol. Chem. pmid:3038865
Hope MJ and Cullis PR Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. 1987 J. Biol. Chem. pmid:3558410
Sripada PK et al. Partial synthesis and properties of a series of N-acyl sphingomyelins. 1987 J. Lipid Res. pmid:3611973
Ichioka T et al. Hematopoietic cell transplantation in murine globoid cell leukodystrophy (the twitcher mouse): effects on levels of galactosylceramidase, psychosine, and galactocerebrosides. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:2884662
Goda S et al. Hydrolysis of galactosylsphingosine and lactosylsphingosine by beta-galactosidases in human brain and cultured fibroblasts. 1987 Biochim. Biophys. Acta pmid:3111543
Hannun YA and Bell RM Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. 1987 Science pmid:3101176
Kobayashi T et al. Globoid cell leukodystrophy is a generalized galactosylsphingosine (psychosine) storage disease. 1987 Biochem. Biophys. Res. Commun. pmid:3579916
Ichioka T et al. Simultaneous determination of psychosine and cerebrosides. 1987 Anal. Biochem. pmid:3674406
Shinoda H et al. Accumulation of galactosylsphingosine (psychosine) in the twitcher mouse: determination by HPLC. 1987 J. Neurochem. pmid:3585345
McIntyre TM et al. Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils. 1987 J. Biol. Chem. pmid:2824456
Vaccarino F et al. Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:2825205
Osiecki-Newman K et al. Human acid beta-glucosidase: use of inhibitors, alternative substrates and amphiphiles to investigate the properties of the normal and Gaucher disease active sites. 1987 Biochim. Biophys. Acta pmid:2956992
Bazzi MD and Nelsestuen GL Mechanism of protein kinase C inhibition by sphingosine. 1987 Biochem. Biophys. Res. Commun. pmid:3606616
Inagaki F et al. Analysis of NMR spectra of sugar chains of glycolipids by multiple relayed COSY and 2D homonuclear Hartman-Hahn spectroscopy. 1987 FEBS Lett. pmid:3803612
Madden TD et al. Modelling the biological membrane. 1987 Biochem. Soc. Trans. pmid:3556743
Wertz PW and Downing DT Covalently bound omega-hydroxyacylsphingosine in the stratum corneum. 1987 Biochim. Biophys. Acta pmid:3790600
Wilson E et al. Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils. 1987 Arch. Biochem. Biophys. pmid:2825597
Burgoyne RD et al. A major role for protein kinase C in calcium-activated exocytosis in permeabilised adrenal chromaffin cells. 1988 FEBS Lett. pmid:3169247
Hamanaka S et al. Occurrence of galactosylceramide in pig epidermal cells. 1988 Biochim. Biophys. Acta pmid:3401502
Lambeth JD et al. Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst. 1988 J. Biol. Chem. pmid:2831206
Igisu H et al. Inhibition of cytochrome c oxidase and hemolysis caused by lysosphingolipids. 1988 Lipids pmid:2840545
Wahl M and Carpenter G Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells by calcium and protein kinase C. 1988 J. Biol. Chem. pmid:3259577
Fan XD et al. Interferon-gamma-induced transcriptional activation is mediated by protein kinase C. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3134657
Wilson E et al. Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. 1988 J. Biol. Chem. pmid:3132460
Winicov I and Gershengorn MC Sphingosine inhibits thyrotropin-releasing hormone binding to pituitary cells by a mechanism independent of protein kinase C. 1988 J. Biol. Chem. pmid:3137221
Canonico PL et al. Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures. 1988 J. Neurochem. pmid:2901459
Phatak PD et al. Protein kinase C modulates actin conformation in human T lymphocytes. 1988 J. Immunol. pmid:3262672
Linnebjerg H et al. Inhibition by amiloride and by Na+-depletion of A23187-stimulated arachidonic acid and histamine release from rat mast cells. 1988 FEBS Lett. pmid:2461320
Tyagi SR et al. Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst. 1988 J. Biol. Chem. pmid:2843513
Civan MM et al. Insulin and phorbol ester stimulate conductive Na+ transport through a common pathway. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3277184
Rider LG et al. Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils. 1988 J. Immunol. pmid:2826587
Tanaka K et al. The twitcher mouse: accumulation of galactosylsphingosine and pathology of the sciatic nerve. 1988 Brain Res. pmid:3409017
Kobayashi T et al. Free sphingoid bases in normal murine tissues. 1988 Eur. J. Biochem. pmid:3350021
Medlock KA and Merrill AH Rapid turnover of sphingosine synthesized de novo from [14C]serine by Chinese hamster ovary cells. 1988 Biochem. Biophys. Res. Commun. pmid:3143361
Malinow R et al. Persistent protein kinase activity underlying long-term potentiation. 1988 Nature pmid:2847049
Kobayashi T et al. Infantile and fetal globoid cell leukodystrophy: analysis of galactosylceramide and galactosylsphingosine. 1988 Ann. Neurol. pmid:3239954
Jefferson AB and Schulman H Sphingosine inhibits calmodulin-dependent enzymes. 1988 J. Biol. Chem. pmid:2844804
Grove DS and Mastro AM Prevention of the TPA-mediated down-regulation of protein kinase C. 1988 Biochem. Biophys. Res. Commun. pmid:3348799
Slivka SR et al. Alpha 1-adrenergic receptors promote phosphatidylcholine hydrolysis in MDCK-D1 cells. A mechanism for rapid activation of protein kinase C. 1988 J. Biol. Chem. pmid:2842326
Sanchez A et al. Thrombin-induced changes of intracellular [Ca2+] and pH in human platelets. Cytoplasmic alkalinization is not a prerequisite for calcium mobilization. 1988 Biochim. Biophys. Acta pmid:2831984
Hirabayashi Y et al. A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids. 1988 J. Biochem. pmid:3360750
Bell RM et al. Protein kinase C regulation by sphingosine/lysosphingolipids. 1988 Cold Spring Harb. Symp. Quant. Biol. pmid:3076075
Gupta AK et al. Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin. 1988 J. Invest. Dermatol. pmid:3171222
Badwey JA et al. Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release. 1988 J. Biol. Chem. pmid:2830263