| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chigorno V et al. | Biosynthesis of gangliosides containing C18:1 and C20:1 [3-14C]sphingosine after administrating [1-14C]palmitic acid and [1-14C]stearic acid to rat cerebellar granule cells in culture. | 1994 | Eur. J. Biochem. | pmid:8181467 |
| Thurman RG et al. | SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat. | 1994 | Transpl. Int. | pmid:11271195 |
| Su Y et al. | Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts. | 1994 | J. Biol. Chem. | pmid:8206962 |
| Kai H et al. | Involvement of protein kinase C in mucus secretion by hamster tracheal epithelial cells in culture. | 1994 | Am. J. Physiol. | pmid:7977763 |
| Mattie M et al. | Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. | 1994 | J. Biol. Chem. | pmid:8106352 |
| Breittmayer JP et al. | Regulation by sphingomyelinase and sphingosine of Ca2+ signals elicited by CD3 monoclonal antibody, thapsigargin, or ionomycin in the Jurkat T cell line. | 1994 | J. Biol. Chem. | pmid:8106482 |
| Kiss Z and Anderson WH | Hydrogen peroxide regulates phospholipase D-mediated hydrolysis of phosphatidylethanolamine and phosphatidylcholine by different mechanisms in NIH 3T3 fibroblasts. | 1994 | Arch. Biochem. Biophys. | pmid:8203906 |
| Natoli G et al. | Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX. | 1994 | Mol. Cell. Biol. | pmid:7507209 |
| Zhao C et al. | Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. | 1994 | J. Biol. Chem. | pmid:8063782 |
| Kachra Z et al. | The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient. | 1994 | Endocrinology | pmid:7507834 |
| Mazurek N et al. | Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response--a preliminary note. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8292009 |
| Kiss Z | Sphingosine-like stimulatory effects of propranolol on phospholipase D activity in NIH 3T3 fibroblasts. | 1994 | Biochem. Pharmacol. | pmid:8185671 |
| Robson KJ et al. | 6-Hydroxy-4-sphingenine in human epidermal ceramides. | 1994 | J. Lipid Res. | pmid:7868984 |
| Gniadecki R | A vitamin D analogue KH 1060 activates the protein kinase C-c-fos signalling pathway to stimulate epidermal proliferation in murine skin. | 1994 | J. Endocrinol. | pmid:7836898 |
| Kiss Z | The zinc chelator 1,10-phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine, but not sphingosine and H2O2, on phospholipase D activity in NIH 3T3 fibroblasts. | 1994 | Biochem. J. | pmid:8129736 |
| Zimber A et al. | Inhibition of proliferation and induction of monocytic differentiation on HL60 human promyelocytic leukemia cells treated with bile acids in vitro. | 1994 | Int. J. Cancer | pmid:7927907 |
| Ohta H et al. | A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils. | 1994 | FEBS Lett. | pmid:7988686 |
| McDonough PM et al. | Control of cardiac Ca2+ levels. Inhibitory actions of sphingosine on Ca2+ transients and L-type Ca2+ channel conductance. | 1994 | Circ. Res. | pmid:7955152 |
| Olivera A et al. | Sphingosine kinase from Swiss 3T3 fibroblasts: a convenient assay for the measurement of intracellular levels of free sphingoid bases. | 1994 | Anal. Biochem. | pmid:7887476 |
| Ohta H et al. | Quantification of free sphingosine in cultured cells by acylation with radioactive acetic anhydride. | 1994 | Anal. Biochem. | pmid:7864378 |
| Flitsch SL et al. | The chemoenzymatic synthesis of neoglycolipids and lipid-linked oligosaccharides using glycosyltransferases. | 1994 | Bioorg. Med. Chem. | pmid:7757420 |
| Chiang TM | Activation of phospholipase D in human platelets by collagen and thrombin and its relationship to platelet aggregation. | 1994 | Biochim. Biophys. Acta | pmid:7948037 |
| Pandol SJ et al. | Sphingosine regulates Ca(2+)-ATPase and reloading of intracellular Ca2+ stores in the pancreatic acinar cell. | 1994 | Biochim. Biophys. Acta | pmid:7918564 |
| Riboni L et al. | Formation of bioactive sphingoid molecules from exogenous sphingomyelin in primary cultures of neurons and astrocytes. | 1994 | FEBS Lett. | pmid:7925994 |
| Webster RJ et al. | Sphingosine effects on the contractile behavior of skinned cardiac myocytes. | 1994 | J. Mol. Cell. Cardiol. | pmid:7869389 |
| Hudson PL et al. | Modulation by sphingolipids of calcium signals evoked by epidermal growth factor. | 1994 | J. Biol. Chem. | pmid:8063833 |
| Scita G and Wolf G | The effect of sphingosine on the release of fibronectin from human lung fibroblasts. | 1994 | Biochim. Biophys. Acta | pmid:8061052 |
| Bennett GS et al. | Differential sensitivity to inhibitors discriminates between two types of kinases responsible for in vivo phosphorylation of different sites in the carboxy-terminal tail of chicken neurofilament-M. | 1994 | Mol. Cell. Neurosci. | pmid:7804606 |
| Areces LB et al. | Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors. | 1994 | J. Biol. Chem. | pmid:7518459 |
| Olivera A et al. | Stereospecificity of sphingosine-induced intracellular calcium mobilization and cellular proliferation. | 1994 | J. Biol. Chem. | pmid:8027049 |
| Pedrera C et al. | Receptor-independent mechanisms are involved in the priming of neutrophil's oxidase by vasoactive intestinal peptide. | 1994 | Regul. Pept. | pmid:7716283 |
| Kõiv A and Kinnunen PK | Binding of DNA to liposomes containing different derivatives of sphingosine. | 1994 | Chem. Phys. Lipids | pmid:7923481 |
| Tschaikowsky K | Protein kinase C inhibitors suppress LPS-induced TNF production in alveolar macrophages and in whole blood: the role of encapsulation into liposomes. | 1994 | Biochim. Biophys. Acta | pmid:8186258 |
| Bhat BG et al. | Hepatic monoacylglycerol acyltransferase is regulated by sn-1,2-diacylglycerol and by specific lipids in Triton X-100/phospholipid-mixed micelles. | 1994 | J. Biol. Chem. | pmid:8175745 |
| Schmelz EM et al. | Uptake and metabolism of sphingolipids in isolated intestinal loops of mice. | 1994 | J. Nutr. | pmid:8169662 |
| Park YS et al. | Liposomal N,N,N-trimethylsphingosine (TMS) as an inhibitor of B16 melanoma cell growth and metastasis with reduced toxicity and enhanced drug efficacy compared to free TMS: cell membrane signaling as a target in cancer therapy III. | 1994 | Cancer Res. | pmid:8174128 |
| Rivas CI et al. | Involvement of the sphingomyelin pathway in autocrine tumor necrosis factor signaling for human immunodeficiency virus production in chronically infected HL-60 cells. | 1994 | Blood | pmid:8161785 |
| Sachs JR | Soluble polycations and cationic amphiphiles inhibit volume-sensitive K-Cl cotransport in human red cell ghosts. | 1994 | Am. J. Physiol. | pmid:8178972 |
| Larivée P et al. | Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranes. | 1994 | Am. J. Respir. Cell Mol. Biol. | pmid:8049080 |
| Ricciolini R et al. | Dexamethasone-dependent modulation of human lymphoblastoid B cell line through sphingosine production. | 1994 | Biochim. Biophys. Acta | pmid:8148386 |
| Boumendjel A and Miller SP | Synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate. | 1994 | J. Lipid Res. | pmid:7897327 |
| Gomez-Muñoz A et al. | Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts. | 1994 | J. Biol. Chem. | pmid:8132631 |
| Singh BN et al. | Identification of the lipid moiety and further characterization of the novel lipophosphoglycan-like glycoconjugates of Trichomonas vaginalis and Trichomonas foetus. | 1994 | Arch. Biochem. Biophys. | pmid:8135538 |
| Yamaguchi Y et al. | The synthetic pathway for glucosylsphingosine in cultured fibroblasts. | 1994 | J. Biochem. | pmid:7852294 |
| Chao CP et al. | Sphingosine-mediated phosphatidylinositol metabolism and calcium mobilization. | 1994 | J. Biol. Chem. | pmid:8119927 |
| Meivar-Levy I et al. | Analysis of glucocerebrosidase activity using N-(1-[14C]hexanoyl)-D-erythroglucosylsphingosine demonstrates a correlation between levels of residual enzyme activity and the type of Gaucher disease. | 1994 | Biochem. J. | pmid:7980395 |
| Persat F et al. | Gangliosides of Echinococcus multilocularis metacestodes. | 1994 | Biochim. Biophys. Acta | pmid:8312377 |
| Hauser JM et al. | Role of ceramide in mitogenesis induced by exogenous sphingoid bases. | 1994 | J. Biol. Chem. | pmid:8120042 |
| Matsumoto M and Barnard EA | Effects of an activator and an inhibitor of protein kinase C on serotonin receptors induced by rat brain mRNA in Xenopus oocytes. | 1994 | Neurosci. Lett. | pmid:8177520 |
| Yung BY et al. | Sphinganine potentiation of dimethyl sulfoxide-induced granulocyte differentiation, increase of alkaline phosphatase activity and decrease of protein kinase C activity in a human leukemia cell line (HL-60). | 1994 | Biochem. Biophys. Res. Commun. | pmid:8135836 |
| Schnaar RL and Needham LK | Thin-layer chromatography of glycosphingolipids. | 1994 | Meth. Enzymol. | pmid:7511203 |
| Riley RT et al. | Dietary fumonisin B1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: a new mechanism of nephrotoxicity. | 1994 | J. Nutr. | pmid:8145083 |
| Van Veldhoven PP and Mannaerts GP | Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase. | 1994 | Biochem. J. | pmid:8192648 |
| Kharlamov A et al. | LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022776 |
| Séror SJ et al. | A mutant cysteinyl-tRNA synthetase affecting timing of chromosomal replication initiation in B. subtilis and conferring resistance to a protein kinase C inhibitor. | 1994 | EMBO J. | pmid:8194536 |
| Lavie Y et al. | Formation of endogenous free sphingoid bases in cells induced by changing medium conditions. | 1994 | Biochim. Biophys. Acta | pmid:8305506 |
| Qian J et al. | Involvement of protein kinase C in the axonal growth-promoting effect on spinal cord neurons by target-derived astrocytes. | 1994 | J. Neurobiol. | pmid:7861122 |
| Dettbarn CA et al. | Modulation of cardiac sarcoplasmic reticulum ryanodine receptor by sphingosine. | 1994 | J. Mol. Cell. Cardiol. | pmid:8006984 |
| Seufferlein T and Rozengurt E | Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. | 1994 | J. Biol. Chem. | pmid:7525558 |
| Khan WA et al. | Identification, partial purification, and characterization of a novel phospholipid-dependent and fatty acid-activated protein kinase from human platelets. | 1994 | J. Biol. Chem. | pmid:8144564 |
| Sadahira Y et al. | Sphingosine-1-phosphate inhibits extracellular matrix protein-induced haptotactic motility but not adhesion of B16 mouse melanoma cells. | 1994 | FEBS Lett. | pmid:8119417 |
| Ghosh TK et al. | Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. | 1994 | J. Biol. Chem. | pmid:8077214 |
| Natarajan V et al. | Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate. | 1994 | Am. J. Respir. Cell Mol. Biol. | pmid:8049083 |
| Knöfler R et al. | N,N,N-trimethylsphingosine modifies aggregatory response and ATP release from platelets in whole blood. | 1994 | Thromb. Res. | pmid:7871492 |
| Rodriguez-Lafrasse C et al. | Free sphingoid bases in tissues from patients with type C Niemann-Pick disease and other lysosomal storage disorders. | 1994 | Biochim. Biophys. Acta | pmid:8204660 |
| Kiss Z and Anderson WH | Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor. | 1994 | Biochem. J. | pmid:8010956 |
| Murphy NP et al. | Is protein kinase C activity required for the N-methyl-D-aspartate-evoked rise in cytosolic Ca2+ in mouse striatal neurons? | 1994 | Eur. J. Neurosci. | pmid:8075826 |
| Schroeder JJ et al. | Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme. | 1994 | J. Biol. Chem. | pmid:8106389 |
| Bird TA et al. | Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase. | 1994 | J. Biol. Chem. | pmid:7527398 |
| Wegenka UM et al. | The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family. | 1994 | Mol. Cell. Biol. | pmid:8164674 |
| Miccheli A et al. | Dexamethasone-dependent modulation of cholesterol levels in human lymphoblastoid B cell line through sphingosine production. | 1994 | Biochim. Biophys. Acta | pmid:8148395 |
| Kõiv A et al. | Differential scanning calorimetry study on the binding of nucleic acids to dimyristoylphosphatidylcholine-sphingosine liposomes. | 1994 | Chem. Phys. Lipids | pmid:7516824 |
| Reza F et al. | Anti-idiotypic monoclonal antibody recognizes a consensus recognition site for phosphatidylserine in phosphatidylserine-specific monoclonal antibody and protein kinase C. | 1994 | FEBS Lett. | pmid:8112460 |
| Cho Y and Ziboh VA | Expression of protein kinase C isozymes in guinea pig epidermis: selective inhibition of PKC-beta activity by 13-hydroxyoctadecadienoic acid-containing diacylglycerol. | 1994 | J. Lipid Res. | pmid:8071613 |
| Seren MS et al. | Orally administered glycolipid derivative LIGA20 reduces infarct volume and behavioral impairment after focal cerebral ischemia. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301588 |
| Maneckjee R and Minna JD | Opioids induce while nicotine suppresses apoptosis in human lung cancer cells. | 1994 | Cell Growth Differ. | pmid:7848904 |
| Pushkareva MYu YA and Hannun | Modulation of cytosolic protein phosphorylation by sphingosylphosphorylcholine. | 1994 | Biochim. Biophys. Acta | pmid:8130276 |
| Petrou S et al. | Structural requirements for charged lipid molecules to directly increase or suppress K+ channel activity in smooth muscle cells. Effects of fatty acids, lysophosphatidate, acyl coenzyme A and sphingosine. | 1994 | J. Gen. Physiol. | pmid:8195783 |
| Zhou XM et al. | Modulation of adenylylcyclase by protein kinase C in human neurotumor SK-N-MC cells: evidence that the alpha isozyme mediates both potentiation and desensitization. | 1994 | J. Neurochem. | pmid:7931287 |
| Sachs CW et al. | Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C. | 1995 | J. Biol. Chem. | pmid:7592889 |
| Slack BE et al. | Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha. | 1995 | Biochem. J. | pmid:7832781 |
| Ohta H et al. | Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation. | 1995 | Cancer Res. | pmid:7834642 |
| Okajima F and Kondo Y | Pertussis toxin inhibits phospholipase C activation and Ca2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells. Implications of GTP-binding protein-coupled receptors for lysosphingolipids. | 1995 | J. Biol. Chem. | pmid:7592844 |
| Berger A et al. | Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7597047 |
| Maulik PR and Shipley GG | X-ray diffraction and calorimetric study of N-lignoceryl sphingomyelin membranes. | 1995 | Biophys. J. | pmid:8580334 |
| Mayhan WG and Didion SP | Activation of protein kinase C does not participate in disruption of the blood-brain barrier to albumin during acute hypertension. | 1995 | Brain Res. | pmid:8574657 |
| Boiron-Sargueil F et al. | Cerebroside formation in the peripheral nervous system of normal and Trembler mice. | 1995 | Neurosci. Lett. | pmid:7783943 |
| Divecha N and Irvine RF | Phospholipid signaling. | 1995 | Cell | pmid:7834746 |
| Wong K et al. | N-acetylsphingosine (C2-ceramide) inhibited neutrophil superoxide formation and calcium influx. | 1995 | J. Biol. Chem. | pmid:7852386 |
| Wei LN et al. | Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine. | 1995 | Mol. Cell. Endocrinol. | pmid:7556883 |
| Strum JC et al. | Ceramide triggers meiotic cell cycle progression in Xenopus oocytes. A potential mediator of progesterone-induced maturation. | 1995 | J. Biol. Chem. | pmid:7768956 |
| Suh HW et al. | Expression of the proenkephalin A gene and [Met5]-enkephalin secretion induced by arachidonic acid in bovine adrenal medullary chromaffin cells: involvement of second messengers. | 1995 | J. Neurochem. | pmid:7830054 |
| Riboni L et al. | A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation. | 1995 | J. Biol. Chem. | pmid:7592930 |
| Törnquist K et al. | Sphingosine derivatives inhibit depolarization-evoked calcium entry in rat GH4C1 cells. | 1995 | Endocrinology | pmid:7588222 |
| Hanafin NM et al. | Increased PKC activity in cultured human keratinocytes and fibroblasts after treatment with 1 alpha, 25-dihydroxyvitamin D3. | 1995 | J. Cell. Biochem. | pmid:7759571 |
| Ridgway ND | 25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells. | 1995 | J. Lipid Res. | pmid:7666011 |
| Gómez-Muñoz A et al. | Interaction of ceramides, sphingosine, and sphingosine 1-phosphate in regulating DNA synthesis and phospholipase D activity. | 1995 | J. Biol. Chem. | pmid:7592842 |
| Xu Y et al. | Effect of lysophospholipids on signaling in the human Jurkat T cell line. | 1995 | J. Cell. Physiol. | pmid:7775587 |
| Kiss Z and Deli E | Preferential inhibition of phorbol ester-induced hydrolysis of phosphatidylethanolamine by N-acetylsphingosine in NIH 3T3 fibroblasts. | 1995 | FEBS Lett. | pmid:7781767 |
| López-GarcÃa F et al. | Effect of sphingosine and stearylamine on the interaction of phosphatidylserine with calcium. A study using DSC, FT-IR and 45Ca(2+)-binding. | 1995 | Biochim. Biophys. Acta | pmid:7794967 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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