| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ouairy CM et al. | Development of an acid ceramidase activity-based probe. | 2015 | Chem. Commun. (Camb.) | pmid:25748248 |
| Desai P et al. | Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. | 2015 | Mol. Cell. Biochem. | pmid:26350564 |
| Ohkawa R et al. | Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. | 2015 | Clin. Biochem. | pmid:25863111 |
| Radue EW et al. | Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. | 2015 | Neurology | pmid:25632085 |
| Wang L et al. | Junctional complex and focal adhesion rearrangement mediates pulmonary endothelial barrier enhancement by FTY720 S-phosphonate. | 2015 | Microvasc. Res. | pmid:25862132 |
| Kolahdooz Z et al. | Sphingosin-1-phosphate Receptor 1: a Potential Target to Inhibit Neuroinflammation and Restore the Sphingosin-1-phosphate Metabolism. | 2015 | Can J Neurol Sci | pmid:25860537 |
| Ren K et al. | Apolipoprotein M. | 2015 | Clin. Chim. Acta | pmid:25858547 |
| Thomas RH and Wakefield RA | Oral disease-modifying therapies for relapsing-remitting multiple sclerosis. | 2015 | Am J Health Syst Pharm | pmid:25511835 |
| Moolenaar WH | Introduction to the ECR special issue on lysophospholipids in biology. | 2015 | Exp. Cell Res. | pmid:25746723 |
| Zhao S and Li J | Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. | 2015 | PLoS ONE | pmid:25748447 |
| Issa NP and Hentati A | VZV encephalitis that developed in an immunized patient during fingolimod therapy. | 2015 | Neurology | pmid:25416038 |
| Lin CC et al. | Sphingosine-1-phosphate mediates ICAM-1-dependent monocyte adhesion through p38 MAPK and p42/p44 MAPK-dependent Akt activation. | 2015 | PLoS ONE | pmid:25734900 |
| Zhang DD et al. | Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors. | 2015 | Biol. Chem. | pmid:25720064 |
| Cozza G et al. | A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. | 2015 | Biochim. Biophys. Acta | pmid:25936777 |
| Till KJ et al. | Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells. | 2015 | J. Immunol. | pmid:25632006 |
| O'Sullivan C and Dev KK | Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. | 2015 | J. Cell. Sci. | pmid:26359302 |
| Slowik A et al. | The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. | 2015 | Br. J. Pharmacol. | pmid:25220526 |
| Oskeritzian CA et al. | The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. | 2015 | J. Allergy Clin. Immunol. | pmid:25512083 |
| Kurano M et al. | LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. | 2015 | J. Biol. Chem. | pmid:25505264 |
| Konstantinou D et al. | Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. | 2015 | Cell Biol. Int. | pmid:25492631 |
| Opal SM and van der Poll T | Endothelial barrier dysfunction in septic shock. | 2015 | J. Intern. Med. | pmid:25418337 |
| Frati A et al. | Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxin. | 2015 | Mol. Endocrinol. | pmid:25415609 |
| Fustero S et al. | Olefin metathesis reactions with fluorinated substrates, catalysts, and solvents. | 2015 | Chem. Rev. | pmid:25047062 |
| Jaramillo-Gómez J et al. | Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy. | 2015 | Neurosci. Lett. | pmid:26222260 |
| Klocke S et al. | Slow-freezing versus vitrification for human ovarian tissue cryopreservation. | 2015 | Arch. Gynecol. Obstet. | pmid:25115279 |
| Czubowicz K et al. | Sphingosine-1-phosphate and its effect on glucose deprivation/glucose reload stress: from gene expression to neuronal survival. | 2015 | Mol. Neurobiol. | pmid:25056275 |
| Siow D et al. | Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. | 2015 | Adv Biol Regul | pmid:25319495 |
| Iwabuchi K et al. | Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. | 2015 | Mediators Inflamm. | pmid:26609196 |
| Mahajan-Thakur S et al. | Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation. | 2015 | Mediators Inflamm. | pmid:26604433 |
| Barnawi J et al. | Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). | 2015 | PLoS ONE | pmid:26485657 |
| Moruno Manchon JF et al. | Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. | 2015 | Sci Rep | pmid:26477494 |
| Wang K et al. | Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. | 2015 | PLoS Genet. | pmid:26474409 |
| Johnson CH et al. | Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. | 2015 | J Neuroimmune Pharmacol | pmid:26232265 |
| Zhang SQ et al. | Mutation of G234 amino acid residue in candida albicans drug-resistance-related protein Rta2p is associated with fluconazole resistance and dihydrosphingosine transport. | 2015 | Virulence | pmid:26220356 |
| Kihara Y et al. | Lysophospholipid receptors in drug discovery. | 2015 | Exp. Cell Res. | pmid:25499971 |
| Le Bihan O et al. | Visualization of adherent cell monolayers by cryo-electron microscopy: A snapshot of endothelial adherens junctions. | 2015 | J. Struct. Biol. | pmid:26470813 |
| Flávia Nardy A et al. | Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease. | 2015 | Biomed Res Int | pmid:26347020 |
| Hsu CK et al. | Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. | 2015 | Br. J. Pharmacol. | pmid:26359950 |
| Höglinger D et al. | Intracellular sphingosine releases calcium from lysosomes. | 2015 | Elife | pmid:26613410 |
| Wisse P et al. | Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy. | 2015 | J. Org. Chem. | pmid:26061009 |
| Gao XY et al. | Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. | 2015 | Oncol. Rep. | pmid:26239167 |
| Adada MM et al. | Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion. | 2015 | FASEB J. | pmid:26209696 |
| Dabkowska AP et al. | Assembly of RNA nanostructures on supported lipid bilayers. | 2015 | Nanoscale | pmid:25417592 |
| Wang H et al. | Sphingosine-1-Phosphate Induces the Migration and Angiogenesis of Epcs Through the Akt Signaling Pathway via Sphingosine-1-Phosphate Receptor 3/Platelet-Derived Growth Factor Receptor-β. | 2015 | Cell. Mol. Biol. Lett. | pmid:26208383 |
| Giese AK et al. | A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease. | 2015 | Orphanet J Rare Dis | pmid:26082315 |
| Absher JR | ACP Journal Club. In multiple sclerosis, use of fingolimod reduced immune responses to influenza and tetanus booster vaccines. | 2015 | Ann. Intern. Med. | pmid:26075785 |
| Han SH et al. | Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells. | 2015 | BMB Rep | pmid:26077028 |
| Malik FA et al. | Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. | 2015 | PLoS ONE | pmid:26079370 |
| Mooren OL et al. | Role of N-WASP in Endothelial Monolayer Formation and Integrity. | 2015 | J. Biol. Chem. | pmid:26070569 |
| Zhang L et al. | FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. | 2015 | Toxicol. Lett. | pmid:25939952 |
| Mani R et al. | ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo. | 2015 | Exp. Hematol. | pmid:25937048 |
| Zonta F et al. | Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. | 2015 | Blood | pmid:25931585 |
| Shih HJ et al. | FTY720 mitigates torsion/detorsion-induced testicular injury in rats. | 2015 | J. Surg. Res. | pmid:25862489 |
| Mori M | Lethal arrhythmia due to fingolimod, a S1P receptor modulator: are we overestimating or underestimating? | 2015 | J. Neurol. Neurosurg. Psychiatry | pmid:25855398 |
| Prager B et al. | Sphingosine 1-phosphate signaling at the blood-brain barrier. | 2015 | Trends Mol Med | pmid:25939882 |
| Rosenberg AJ et al. | A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. | 2015 | Appl Radiat Isot | pmid:25931137 |
| Zheng XD et al. | Role of Sphk1 in the malignant transformation of breast epithelial cells and breast cancer progression. | 2014 Oct-Dec | Indian J Cancer | pmid:26842184 |
| Rao PV | Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. | 2014 Mar-Apr | J Ocul Pharmacol Ther | pmid:24283588 |
| Chang N et al. | Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. | 2014 | J. Cell. Biochem. | pmid:24038457 |
| Fu Y et al. | Impact of an immune modulator fingolimod on acute ischemic stroke. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25489101 |
| Tan KB et al. | Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia. | 2014 | Nanomedicine (Lond) | pmid:24294981 |
| Xing Y et al. | FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1. | 2014 | J Dig Dis | pmid:24868599 |
| Uhlig S et al. | Differential regulation of lung endothelial permeability in vitro and in situ. | 2014 | Cell. Physiol. Biochem. | pmid:24977477 |
| Sedal L et al. | Current management of relapsing-remitting multiple sclerosis. | 2014 | Intern Med J | pmid:25302718 |
| Nagamatsu T et al. | Emerging roles for lysophospholipid mediators in pregnancy. | 2014 | Am. J. Reprod. Immunol. | pmid:24689547 |
| Gao M et al. | Prolonging survival of corneal transplantation by selective sphingosine-1-phosphate receptor 1 agonist. | 2014 | PLoS ONE | pmid:25216235 |
| Wei N et al. | Altered sphingoid base profiles in type 1 compared to type 2 diabetes. | 2014 | Lipids Health Dis | pmid:25305670 |
| Omidbakhsh R et al. | Fingolimod affects gene expression profile associated with LPS-induced memory impairment. | 2014 | Exp Brain Res | pmid:25098558 |
| Xu M et al. | FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway. | 2014 | Acta Pharmacol. Sin. | pmid:25399649 |
| Watanabe C et al. | Antagonism and synergy of single chain sphingolipids sphingosine and sphingosine-1-phosphate toward lipid bilayer properties. Consequences for their role as cell fate regulators. | 2014 | Langmuir | pmid:25386673 |
| Dai Z and Green TK | Synthesis of aromatic sphingosine analogues by diastereoselective amination of enantioenriched trans-γ,δ-unsaturated β-hydroxyesters. | 2014 | J. Org. Chem. | pmid:25046474 |
| Colombo E et al. | Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide. | 2014 | Ann. Neurol. | pmid:25043204 |
| Leanza L et al. | Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines. | 2014 | Curr. Pharm. Des. | pmid:23701546 |
| Yagoub D et al. | Sphingosine kinase 1 isoform-specific interactions in breast cancer. | 2014 | Mol. Endocrinol. | pmid:25216046 |
| di Nuzzo L et al. | Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis. | 2014 | Drug Des Devel Ther | pmid:24876766 |
| Rolin J and Maghazachi AA | Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. | 2014 | J. Leukoc. Biol. | pmid:24493826 |
| Li MH et al. | Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. | 2014 | J. Pediatr. Surg. | pmid:25092091 |
| Marfia G et al. | Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells. | 2014 | Glia | pmid:25042636 |
| Grammatikos G et al. | Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease. | 2014 | Biochim. Biophys. Acta | pmid:24769340 |
| Halmer R et al. | Sphingolipids: important players in multiple sclerosis. | 2014 | Cell. Physiol. Biochem. | pmid:24977485 |
| Laroni A et al. | Safety of the first dose of fingolimod for multiple sclerosis: results of an open-label clinical trial. | 2014 | BMC Neurol | pmid:24690227 |
| Arlt O et al. | Sphingosine-1-phosphate modulates dendritic cell function: focus on non-migratory effects in vitro and in vivo. | 2014 | Cell. Physiol. Biochem. | pmid:24977479 |
| Poersch AB et al. | Involvement of oxidative stress in subacute toxicity induced by fumonisin B1 in broiler chicks. | 2014 | Vet. Microbiol. | pmid:25219295 |
| Janes K et al. | The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. | 2014 | J. Biol. Chem. | pmid:24876379 |
| Zhang GQ et al. | Sphingosine-1-phosphate receptors respond differently to early myocardial ischemia and ischemia-reperfusion in vivo. | 2014 | Sheng Li Xue Bao | pmid:24777407 |
| Jokubaitis VG et al. | Fingolimod after natalizumab and the risk of short-term relapse. | 2014 | Neurology | pmid:24610329 |
| Ceglarek U et al. | Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. | 2014 | Clin. Chim. Acta | pmid:24768784 |
| Miyazaki Y et al. | Suppressed pro-inflammatory properties of circulating B cells in patients with multiple sclerosis treated with fingolimod, based on altered proportions of B-cell subpopulations. | 2014 | Clin. Immunol. | pmid:24607506 |
| Shin KO et al. | Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells. | 2014 | Arch. Pharm. Res. | pmid:24687256 |
| Bird CH et al. | The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress. | 2014 | Cell Death Differ. | pmid:24488096 |
| Kerage D et al. | Review: novel insights into the regulation of vascular tone by sphingosine 1-phosphate. | 2014 | Placenta | pmid:24411702 |
| Anthony DC et al. | Investigation of immune and CNS-mediated effects of fingolimod in the focal delayed-type hypersensitivity multiple sclerosis model. | 2014 | Neuropharmacology | pmid:24412675 |
| Fernández Ó et al. | [Usefulness of electronic drug registers: Spanish register of patients treated with fingolimod (Gilenya ®)]. | 2014 | Rev Neurol | pmid:24399624 |
| Mendes-Braz M et al. | The effects of glucose and lipids in steatotic and non-steatotic livers in conditions of partial hepatectomy under ischaemia-reperfusion. | 2014 | Liver Int. | pmid:24107124 |
| Egom EE | Sphingosine-1-phosphate signalling as a therapeutic target for patients with abnormal glucose metabolism and ischaemic heart disease. | 2014 | J Cardiovasc Med (Hagerstown) | pmid:23839592 |
| Voon V et al. | Fingolimod-induced atrioventricular conduction defects in a young lady with multiple sclerosis--insights into possible drug mechanism. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24309839 |
| Di Pardo A et al. | FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease. | 2014 | Hum. Mol. Genet. | pmid:24301680 |
| Spinedi A | Brefeldin A limits N-hexanoylsphingosine-induced accumulation of natural ceramide via the salvage pathway by enhancing glucosylation. | 2014 | Lipids | pmid:24194457 |
| Welford RW et al. | Plasma lysosphingomyelin demonstrates great potential as a diagnostic biomarker for Niemann-Pick disease type C in a retrospective study. | 2014 | PLoS ONE | pmid:25479233 |
| Chawla S et al. | Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. | 2014 | Lipids | pmid:24190514 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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