sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Kasbi-Chadli F et al. Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle sphingolipid synthesis in offspring hamsters fed a high-fat diet. 2016 Eur J Nutr pmid:25787885
Fu P et al. Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. 2016 J. Biol. Chem. pmid:27864331
Sasset L et al. Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. 2016 Trends Endocrinol. Metab. pmid:27562337
Roviezzo F et al. Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate. 2016 Pharmacol. Res. pmid:27713021
Hemdan NY et al. Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsis. 2016 Eur. J. Immunol. pmid:27683081
Chew WS et al. To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. 2016 Pharmacol. Res. pmid:27663260
Gazit SL et al. Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock. 2016 Circ. Res. pmid:27582371
Machida T et al. Cellular function and signaling pathways of vascular smooth muscle cells modulated by sphingosine 1-phosphate. 2016 J. Pharmacol. Sci. pmid:27581589
Nagahashi M et al. High levels of sphingolipids in human breast cancer. 2016 J. Surg. Res. pmid:27565080
Dong T et al. Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury. 2016 J Neuroinflammation pmid:27561600
Harijith A et al. Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. 2016 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27343196
Hernández-Coronado CG et al. Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. 2016 Gen. Comp. Endocrinol. pmid:27342378
Chakrabarti SS et al. Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease. 2016 Curr Alzheimer Res pmid:27335046
Nagura Y et al. Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. 2016 Transfus Med pmid:27350440
Sanchez T Sphingosine-1-Phosphate Signaling in Endothelial Disorders. 2016 Curr Atheroscler Rep pmid:27115142
Crespo I et al. Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. 2016 J. Pineal Res. pmid:27101794
Riganti L et al. Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. 2016 J. Neurosci. pmid:27098703
Cai Y et al. FOXF1 maintains endothelial barrier function and prevents edema after lung injury. 2016 Sci Signal pmid:27095594
Fujii C et al. Altered T cell phenotypes associated with clinical relapse of multiple sclerosis patients receiving fingolimod therapy. 2016 Sci Rep pmid:27752051
Zhang H et al. Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. 2016 Sci Rep pmid:27476912
Gao H et al. Bacillus cereus strain S2 shows high nematicidal activity against Meloidogyne incognita by producing sphingosine. 2016 Sci Rep pmid:27338781
Zhang M et al. Critical Role of COI1-Dependent Jasmonate Pathway in AAL toxin induced PCD in Tomato Revealed by Comparative Proteomics. 2016 Sci Rep pmid:27324416
Jin J et al. Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate. 2016 Sci Rep pmid:26948042
Guerrero M et al. Sphingosine 1-phosphate receptor 1 agonists: a patent review (2013-2015). 2016 Expert Opin Ther Pat pmid:26947494
Watterson SH et al. Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series. 2016 J. Med. Chem. pmid:26924461
Kim SE et al. The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. 2016 Invest. Ophthalmol. Vis. Sci. pmid:26830367
Messias CV et al. Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. 2016 PLoS ONE pmid:26824863
Pászti-Gere E et al. Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. 2016 Oxid Med Cell Longev pmid:26823955
Vijai Kumar Reddy T et al. Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents. 2016 Eur J Med Chem pmid:27128176
Wiltshire R et al. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. 2016 Sci Rep pmid:26813587
Farez MF and Correale J Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. 2016 J. Neurol. Sci. pmid:26810518
Santos-Cortez RL et al. Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2. 2016 Am. J. Hum. Genet. pmid:26805784
Xu R et al. Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response. 2016 Oncotarget pmid:26943039
Fan A et al. Liver X receptor-α and miR-130a-3p regulate expression of sphingosine 1-phosphate receptor 2 in human umbilical vein endothelial cells. 2016 Am. J. Physiol., Cell Physiol. pmid:26669941
Ordóñez YF et al. 3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells. 2016 Mol Biosyst pmid:26928714
Petrache I and Berdyshev EV Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. 2016 Annu. Rev. Physiol. pmid:26667073
Delgado A and Martínez-Cartro M Therapeutic Potential of the Modulation of Sphingosine-1-Phosphate Receptors. 2016 Curr. Med. Chem. pmid:26639095
Zeng Y et al. Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. 2016 Oncotarget pmid:27556509
Nagahashi M et al. DNA damage response and sphingolipid signaling in liver diseases. 2016 Surg. Today pmid:26514817
Zhang D et al. FTY-720P Suppresses Osteoclast Formation by Regulating Expression of Interleukin-6 (IL-6), Interleukin-4 (IL-4), and Matrix Metalloproteinase 2 (MMP-2). 2016 Med. Sci. Monit. pmid:27344392
Yönel N et al. Anti-erosive effects of fluoride and phytosphingosine: an in vitro study. 2016 Eur. J. Oral Sci. pmid:27342101
Li N and Zhang F Implication of sphingosin-1-phosphate in cardiovascular regulation. 2016 Front Biosci (Landmark Ed) pmid:27100508
Kalhori V et al. FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. 2016 Endocr. Relat. Cancer pmid:26935838
Bae YC et al. Effects of sphingosylphosphorylcholine on cryopreserved fat tissue graft survival. 2016 Mol Med Rep pmid:27572900
Vanier MT et al. Diagnostic tests for Niemann-Pick disease type C (NP-C): A critical review. 2016 Mol. Genet. Metab. pmid:27339554
Liu X et al. Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. 2016 Exp. Biol. Med. (Maywood) pmid:26376826
Gowda SG et al. Highly efficient preparation of sphingoid bases from glucosylceramides by chemoenzymatic method. 2016 J. Lipid Res. pmid:26667669
Lee WJ et al. Inhibitory effects of N,N,N-trimethyl phytosphingosine-iodide on melanogenesis via ERK activation-mediated MITF degradation. 2016 Biosci. Biotechnol. Biochem. pmid:26263195
Grammatikos G et al. Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma. 2016 Oncotarget pmid:26933996
Stahlberg S et al. Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. 2016 Langmuir pmid:26828109