sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for sphingosine

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with sphingosine

Download all related citations
Per page 10 20 50 100 | Total 6563
Authors Title Published Journal PubMed Link
Bornfeldt KE et al. Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. 1995 J. Cell Biol. pmid:7790372
Wu J et al. Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. 1995 J. Biol. Chem. pmid:7744787
Yatomi Y et al. Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride. 1995 Anal. Biochem. pmid:7503424
Cao YZ et al. The mechanism of sphingosine enhancement of phorbol ester-mediated phospholipase D activation in lymphocytes. 1995 Biochem. Biophys. Res. Commun. pmid:8554615
Hazel BA et al. Benzene and its metabolite, hydroquinone, induce granulocytic differentiation in myeloblasts by interacting with cellular signaling pathways activated by granulocyte colony-stimulating factor. 1995 Stem Cells pmid:7542115
Lauritzen L and Hansen HS Differential phospholipid-labeling suggests two subtypes of phospholipase D in rat Leydig cells. 1995 Biochem. Biophys. Res. Commun. pmid:8554594
Casellato R et al. Isolation and structural characterization of N-acetyl- and N-glycolylneuraminic-acid-containing GalNAc-GD1a isomers, IV4GalNAcIV3Neu5AcII3Neu5GcGgOse4Cer and IV4GalNAcIV3Neu5GcII3Neu5AcGgOse4Cer, from bovine brain. 1995 Eur. J. Biochem. pmid:8575436
Katoh N Inhibition by phospholipids, lysophospholipids and gangliosides of melittin-induced phosphorylation in bovine mammary gland. 1995 Toxicology pmid:8560504
Hemmings HC et al. Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C. 1995 Anesth. Analg. pmid:7486107
Iwata M et al. Sphingosine: a mediator of acute renal tubular injury and subsequent cytoresistance. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7568054
Aussel C et al. Sphingosine, oleylamine and stearylamine inhibit both CD11a/CD18-dependent and -independent homotypic aggregation: demonstration by cytofluorimetry. 1995 Immunol. Lett. pmid:8747715
Nishio H and Mori K Synthesis of the esterified cerebroside in the epidermis of guinea pigs. 1995 Biosci. Biotechnol. Biochem. pmid:8520109
Dbaibo GS et al. Activation of a retinoblastoma-protein-dependent pathway by sphingosine. 1995 Biochem. J. pmid:7654183
Lau B and Macdonald PM Determination of the pKa of membrane-bound N,N-dimethylsphingosine using deuterium NMR spectroscopy. 1995 Biochim. Biophys. Acta pmid:7619840
Murohara T et al. Myocardial and endothelial protection by TMS in ischemia-reperfusion injury. 1995 Am. J. Physiol. pmid:7544541
Rigby AC et al. 2H-NMR study of two probe-labelled glycosphingolipid-derived signalling modulators in bilayer membranes. 1995 Biochim. Biophys. Acta pmid:7495851
Morris RC et al. Activation of transfer RNA-guanine ribosyltransferase by protein kinase C. 1995 Nucleic Acids Res. pmid:7630727
Kasinathan C et al. Effect of lipids on glycoprotein sulphotransferase activity in rat submandibular salivary glands. 1995 Arch. Oral Biol. pmid:7639646
Lister MD et al. Interaction of sphingomyelinase with sphingomyelin analogs modified at the C-1 and C-3 positions of the sphingosine backbone. 1995 Biochim. Biophys. Acta pmid:7742352
Hung CY et al. Temperature-induced alteration of inositolphosphorylceramides in the putative glycosylated lipid precursors of Tetrahymena mimbres glycosylphosphatidylinositol-anchored proteins. 1995 Biochem. J. pmid:7717964
Terrian DM and Ways DK Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly. 1995 J. Neurochem. pmid:7798912
Coroneos E et al. Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation. 1995 J. Biol. Chem. pmid:7559485
Shah J et al. Structural and thermotropic properties of synthetic C16:0 (palmitoyl) ceramide: effect of hydration. 1995 J. Lipid Res. pmid:8558082
Campbell XZ and Neet KE Hierarchical analysis of the nerve growth factor-dependent and nerve growth factor-independent differentiation signaling pathways in PC12 cells with protein kinase inhibitors. 1995 J. Neurosci. Res. pmid:8568921
Müller G et al. PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid. 1995 EMBO J. pmid:7744003
Law B and Rossie S The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide. 1995 J. Biol. Chem. pmid:7759536
Ridgway ND Inhibition of acyl-CoA:cholesterol acyltransferase in Chinese hamster ovary (CHO) cells by short-chain ceramide and dihydroceramide. 1995 Biochim. Biophys. Acta pmid:7742354
Bouhours JF and Bouhours D Biochemical characterization of blood group-active glycosphingolipids. 1995 Transfus Clin Biol pmid:8542020
Sofer A and Futerman AH Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP. 1995 J. Biol. Chem. pmid:7744860
Persat F et al. Free ceramides of Echinococcus multilocularis metacestodes. 1995 Biochim. Biophys. Acta pmid:7734444
Ridgway ND and Merriam DL Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells. 1995 Biochim. Biophys. Acta pmid:7742357
Ramasamy S et al. Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture. 1995 Toxicol. Appl. Pharmacol. pmid:7645031
Hanada K et al. Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes. 1995 J. Biol. Chem. pmid:7890763
Jones MJ and Murray AW Evidence that ceramide selectively inhibits protein kinase C-alpha translocation and modulates bradykinin activation of phospholipase D. 1995 J. Biol. Chem. pmid:7890607
Prelusky DB et al. Pilot study on the plasma pharmacokinetics of fumonisin B1 in cows following a single dose by oral gavage or intravenous administration. 1995 Nat. Toxins pmid:8581325
Gumprecht LA et al. Effects of intravenous fumonisin B1 in rabbits: nephrotoxicity and sphingolipid alterations. 1995 Nat. Toxins pmid:8581326
Sawai H et al. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. 1995 J. Biol. Chem. pmid:7592995
Bartschat DK and Rhodes TE Protein kinase C modulates calcium channels in isolated presynaptic nerve terminals of rat hippocampus. 1995 J. Neurochem. pmid:7536806
Sugita M et al. Structural elucidation of two novel amphoteric glycosphingolipids from the earthworm, Pheretima hilgendorfi. 1995 Biochim. Biophys. Acta pmid:8541328
Nishio H and Mori K Reinvestigation of the structure of the esterified cerebroside in the epidermis of guinea pigs. 1995 Biosci. Biotechnol. Biochem. pmid:8520108
Kisic A et al. Sphingolipid bases. A revisitation of the O-methyl derivatives of sphingosine. Isolation and characterization of diacetate derivatives, with revised 13C nuclear magnetic resonance assignments for D-erythro-sphingosine. 1995 J. Lipid Res. pmid:7616124
Rajewski RA et al. Stereo-specific analysis of a novel protein kinase C inhibitor. 1995 J Pharm Biomed Anal pmid:7619884
De Ceuster P et al. Identification and subcellular localization of sphinganine-phosphatases in rat liver. 1995 Biochem. J. pmid:7575445
Stewart ME and Downing DT Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. 1995 J. Invest. Dermatol. pmid:7561168
Smith ER and Merrill AH Differential roles of de novo sphingolipid biosynthesis and turnover in the "burst" of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture. 1995 J. Biol. Chem. pmid:7642524
Schneider JS and Distefano L Response of the damaged dopamine system to GM1 and semisynthetic gangliosides: effects of dose and extent of lesion. 1995 Neuropharmacology pmid:7566482
Kedderis LB et al. Toxicity of the protein kinase C inhibitor safingol administered alone and in combination with chemotherapeutic agents. 1995 Fundam Appl Toxicol pmid:7665004
Huang C et al. Repression of protein kinase C and stimulation of cyclic AMP response elements by fumonisin, a fungal encoded toxin which is a carcinogen. 1995 Cancer Res. pmid:7712470
Zorn NE and Sauro MD Retinoic acid induces translocation of protein kinase C (PKC) and activation of nuclear PKC (nPKC) in rat splenocytes. 1995 Int. J. Immunopharmacol. pmid:7672881
Yatomi Y et al. Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets. 1995 Blood pmid:7795224
Masamune A et al. N,N,N-trimethylsphingosine inhibits interleukin-1 beta-induced NF-kappa B activation and consequent E-selectin expression in human umbilical vein endothelial cells. 1995 FEBS Lett. pmid:7540991
Megidish T et al. The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells. 1995 Biochem. Biophys. Res. Commun. pmid:7488188
Liu R et al. Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellualr stores. 1995 Biochem. Biophys. Res. Commun. pmid:7677781
Jalink K et al. Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. 1995 Biochem. J. pmid:7733903
Goodemote KA et al. Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate. 1995 J. Biol. Chem. pmid:7730331
Abbas HK et al. Biological activities of synthetic analogues of Alternaria alternata toxin (AAL-toxin) and fumonisin in plant and mammalian cell cultures. 1995 Phytochemistry pmid:8590636
Kitano I et al. The effect of protein kinase C stimulator and inhibitor on cochlear potentials in the guinea pig. 1995 Hear. Res. pmid:7559166
Bünemann M et al. Activation of muscarinic K+ current in guinea-pig atrial myocytes by sphingosine-1-phosphate. 1995 J. Physiol. (Lond.) pmid:8788935
Bitar KN and Yamada H Modulation of smooth muscle contraction by sphingosylphosphorylcholine. 1995 Am. J. Physiol. pmid:7573447
Laviada ID et al. Phosphatidylcholine-phospholipase C mediates the induction of nerve growth factor in cultured glial cells. 1995 FEBS Lett. pmid:7758586
Seufferlein T and Rozengurt E Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein. 1995 J. Biol. Chem. pmid:7592645
Seufferlein T and Rozengurt E Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway. 1995 J. Biol. Chem. pmid:7592646
Dettbarn C et al. Involvement of ryanodine receptors in sphingosylphosphorylcholine-induced calcium release from brain microsomes. 1995 Brain Res. pmid:7712168
Kim S et al. Sphingolipid-gated Ca2+ release from intracellular stores of endothelial cells is mediated by a novel Ca(2+)-permeable channel. 1995 J. Biol. Chem. pmid:7890637
van Koppen C et al. Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate. 1996 J. Biol. Chem. pmid:8567663
Yeung JM et al. Fumonisin B1 induces protein kinase C translocation via direct interaction with diacylglycerol binding site. 1996 Toxicol. Appl. Pharmacol. pmid:8917690
Orlati S et al. Sphingosine-induced inhibition of capacitative calcium influx in CFPAC-1 cells. 1996 Cell Calcium pmid:8955554
Suzuki S et al. A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes. 1996 Immunology pmid:9014815
Premakumara GA et al. Isolation of a non-steroidal contragestative agent from Sri Lankan marine red alga, Gelidiella acerosa. 1996 Contraception pmid:8968667
Tokura Y et al. Th2 suppressor cells are more susceptible to sphingosine than Th1 cells in murine contact photosensitivity. 1996 J. Invest. Dermatol. pmid:8752836
Spiegel S and Milstien S Sphingoid bases and phospholipase D activation. 1996 Chem. Phys. Lipids pmid:8681426
Coroneos E et al. Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades. 1996 Biochem. J. pmid:8645194
Karasavvas N et al. Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine. The ceramide amide group is not required for apoptosis. 1996 Eur. J. Biochem. pmid:8612651
Scalia R et al. Myocardial protection by N,N,N-trimethylsphingosine in ischemia reperfusion injury is mediated by inhibition of P-selectin. 1996 J. Leukoc. Biol. pmid:8604008
Suzuki S et al. A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation. 1996 Transplantation pmid:8600623
Groener JE et al. Metabolic fate of oleic acid derived from lysosomal degradation of cholesteryl oleate in human fibroblasts. 1996 J. Lipid Res. pmid:8978478
Uhrig ML et al. Characterization of inositolphospholipids in Trypanosoma cruzi trypomastigote forms. 1996 Biochim. Biophys. Acta pmid:8679689
Sakakura C et al. Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation. 1996 FEBS Lett. pmid:8635587
Witty JP et al. Induction of apoptotic cell death in hen granulosa cells by ceramide. 1996 Endocrinology pmid:8940345
McKay C and Miller A Relationship among cellular diacylglycerol, sphingosine formation, protein kinase C activity, and parathyroid hormone secretion from dispersed bovine parathyroid cells. 1996 Endocrinology pmid:8641201
Nickels JT and Broach JR A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae. 1996 Genes Dev. pmid:8600023
Latinis KM and Koretzky GA Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. 1996 Blood pmid:8562955
Abe A et al. A novel enzyme that catalyzes the esterification of N-acetylsphingosine. Metabolism of C2-ceramides. 1996 J. Biol. Chem. pmid:8662981
Hirschberg K et al. Ganglioside synthesis during the development of neuronal polarity. Major changes occur during axonogenesis and axon elongation, but not during dendrite growth or synaptogenesis. 1996 J. Biol. Chem. pmid:8663007
Kaipia A et al. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. 1996 Endocrinology pmid:8895358
Valsecchi M et al. Changes of free long-chain bases in neuronal cells during differentiation and aging in culture. 1996 J. Neurochem. pmid:8863491
Badiani K et al. Effect of fumonisin B1 on phosphatidylethanolamine biosynthesis in Chinese hamster ovary cells. 1996 Biochim. Biophys. Acta pmid:8982265
Yang SD et al. Okadaic acid, sphingosine, and phorbol ester reversibly modulate heat induction on protein kinase FA/GSK-3 alpha in A431 cells. 1996 J. Cell. Biochem. pmid:8655632
Inooka S and Toyokuni T Sphingosine transfer in cell-to-cell interaction. 1996 Biochem. Biophys. Res. Commun. pmid:8579607
Van Koppen CJ et al. A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils. 1996 Mol. Pharmacol. pmid:8649355
Okajima F et al. Involvement of pertussis toxin-sensitive GTP-binding proteins in sphingosine 1-phosphate-induced activation of phospholipase C-Ca2+ system in HL60 leukemia cells. 1996 FEBS Lett. pmid:8603702
Cuvillier O et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. 1996 Nature pmid:8657285
Postma FR et al. Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. 1996 EMBO J. pmid:8665846
Yoo HS et al. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. 1996 Toxicol. Appl. Pharmacol. pmid:8658522
Sun L et al. A new wound healing agent--sphingosylphosphorylcholine. 1996 J. Invest. Dermatol. pmid:8601721
Hung WC and Chuang LY Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product. 1996 Biochem. Biophys. Res. Commun. pmid:8954076
Yang L et al. Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate. 1996 Biochem. Biophys. Res. Commun. pmid:8954916
Yasui K and Palade P Sphingolipid actions on sodium and calcium currents of rat ventricular myocytes. 1996 Am. J. Physiol. pmid:8779930
Murata Y et al. Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency? 1996 J. Invest. Dermatol. pmid:8752664
Usuki S et al. Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol. 1996 J. Neurochem. pmid:8863486