| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chang N et al. | Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. | 2014 | J. Cell. Biochem. | pmid:24038457 |
| Das A et al. | Delivery of S1P receptor-targeted drugs via biodegradable polymer scaffolds enhances bone regeneration in a critical size cranial defect. | 2014 | J Biomed Mater Res A | pmid:23640833 |
| Roviezzo F et al. | Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate. | 2014 | Clin. Sci. | pmid:24131465 |
| Arya D et al. | Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. | 2014 | J. Biomed. Sci. | pmid:24898615 |
| Maceyka M and Spiegel S | Sphingolipid metabolites in inflammatory disease. | 2014 | Nature | pmid:24899305 |
| Yamamoto R et al. | ASP4058, a novel agonist for sphingosine 1-phosphate receptors 1 and 5, ameliorates rodent experimental autoimmune encephalomyelitis with a favorable safety profile. | 2014 | PLoS ONE | pmid:25347187 |
| Lu Z et al. | FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling. | 2014 | BMC Cancer | pmid:25344679 |
| Anderson G and Maes M | Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions. | 2014 | CNS Neurol Disord Drug Targets | pmid:24040808 |
| Waeber C and Walther T | Sphingosine-1-phosphate as a potential target for the treatment of myocardial infarction. | 2014 | Circ. J. | pmid:24632793 |
| Fragoso YD et al. | The real-life experience with cardiovascular complications in the first dose of fingolimod for multiple sclerosis. | 2014 | Arq Neuropsiquiatr | pmid:25252236 |
| Sato DK and Callegaro D | Oral fingolimod to treat multiple sclerosis: see your cardiologist first. | 2014 | Arq Neuropsiquiatr | pmid:25252227 |
| Bridel C and Lalive PH | Update on multiple sclerosis treatments. | 2014 | Swiss Med Wkly | pmid:25247669 |
| Takeo T et al. | Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. | 2014 | Cryobiology | pmid:24201107 |
| Muris AH et al. | Fingolimod in active multiple sclerosis: an impressive decrease in Gd-enhancing lesions. | 2014 | BMC Neurol | pmid:25138918 |
| Langeslag M et al. | Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons. | 2014 | Mol Pain | pmid:25431213 |
| Blanc CA et al. | FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination. | 2014 | J Neuroinflammation | pmid:25138356 |
| Callihan P et al. | Convergent regulation of neuronal differentiation and Erk and Akt kinases in human neural progenitor cells by lysophosphatidic acid, sphingosine 1-phosphate, and LIF: specific roles for the LPA1 receptor. | 2014 | ASN Neuro | pmid:25424429 |
| Kułakowska A et al. | Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis. | 2014 | J Neuroinflammation | pmid:25421616 |
| Franklin MA et al. | Frequency and economic impact of comorbid cardiac conditions with multiple sclerosis. | 2014 | J Manag Care Spec Pharm | pmid:25062072 |
| Chen L et al. | FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels. | 2014 | PLoS ONE | pmid:25050888 |
| Dai L et al. | Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? | 2014 | Cancer Invest. | pmid:24499107 |
| Aliouane L et al. | Synthesis of fluorinated agonist of sphingosine-1-phosphate receptor 1. | 2014 | Bioorg. Med. Chem. | pmid:25047939 |
| Dai Z and Green TK | Synthesis of aromatic sphingosine analogues by diastereoselective amination of enantioenriched trans-γ,δ-unsaturated β-hydroxyesters. | 2014 | J. Org. Chem. | pmid:25046474 |
| Degagné E et al. | Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. | 2014 | J. Clin. Invest. | pmid:25347472 |
| Wang F and Ye P | Improving heart function by modulating myocardiocyte autophagy: a possible novel mechanism for cardiovascular protection of high-density lipoprotein. | 2014 | Lipids Health Dis | pmid:25339382 |
| Keller J et al. | Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. | 2014 | Nat Commun | pmid:25333900 |
| Tao C et al. | Regulation of glucose and lipid homeostasis by adiponectin: effects on hepatocytes, pancreatic β cells and adipocytes. | 2014 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:24417945 |
| Hamidi S et al. | TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts. | 2014 | Biochim. Biophys. Acta | pmid:24440818 |
| Schaper K et al. | Sphingosine-1-phosphate differently regulates the cytokine production of IL-12, IL-23 and IL-27 in activated murine bone marrow derived dendritic cells. | 2014 | Mol. Immunol. | pmid:24434636 |
| Sasaki H et al. | Regulation of alkaline ceramidase activity by the c-Src-mediated pathway. | 2014 | Arch. Biochem. Biophys. | pmid:24708996 |
| Liu M et al. | Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. | 2014 | J. Biol. Chem. | pmid:24318881 |
| Huang YL et al. | Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. | 2014 | Cell. Signal. | pmid:24333325 |
| Xiong Y et al. | Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development. | 2014 | J. Clin. Invest. | pmid:25250575 |
| Tan SJ et al. | Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity. | 2014 | Reprod. Biomed. Online | pmid:25246113 |
| Rojas-Charry L et al. | Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. | 2014 | Neurotoxicology | pmid:24792327 |
| Nagahashi M et al. | Sphingosine-1-phosphate transporters as targets for cancer therapy. | 2014 | Biomed Res Int | pmid:25133174 |
| Nguyen AV et al. | STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. | 2014 | World J. Gastroenterol. | pmid:25132744 |
| Kim ES et al. | Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. | 2014 | Oncogene | pmid:23955082 |
| Thomas K et al. | Fingolimod in a patient with heart failure on the background of pulmonary arterial hypertension and coronary artery disease. | 2014 | BMC Neurol | pmid:24906818 |
| Qian J et al. | FTY720 attenuates paraquat-induced lung injury in mice. | 2014 | Int. Immunopharmacol. | pmid:24893116 |
| di Nuzzo L et al. | Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis. | 2014 | Drug Des Devel Ther | pmid:24876766 |
| Rolin J and Maghazachi AA | Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. | 2014 | J. Leukoc. Biol. | pmid:24493826 |
| Moon MH et al. | Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes. | 2014 | Int. J. Mol. Med. | pmid:25050633 |
| Wakashima T et al. | Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation. | 2014 | J. Biol. Chem. | pmid:25049234 |
| Siciliano C et al. | Synthesis of D-erythro-sphinganine through serine-derived α-amino epoxides. | 2014 | J. Org. Chem. | pmid:24807867 |
| Jiménez-Rojo N et al. | Sphingosine induces the aggregation of imine-containing peroxidized vesicles. | 2014 | Biochim. Biophys. Acta | pmid:24802275 |
| Lima S et al. | A real-time high-throughput fluorescence assay for sphingosine kinases. | 2014 | J. Lipid Res. | pmid:24792926 |
| Pippa R et al. | Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity. | 2014 | Leukemia | pmid:24781014 |
| Rauch BH | Sphingosine 1-phosphate as a link between blood coagulation and inflammation. | 2014 | Cell. Physiol. Biochem. | pmid:24977491 |
| Sattler K et al. | HDL-bound sphingosine 1-phosphate (S1P) predicts the severity of coronary artery atherosclerosis. | 2014 | Cell. Physiol. Biochem. | pmid:24977490 |
| Thuy AV et al. | Sphingosine 1-phosphate in blood: function, metabolism, and fate. | 2014 | Cell. Physiol. Biochem. | pmid:24977489 |
| van Echten-Deckert G et al. | Sphingosine-1-phosphate: boon and bane for the brain. | 2014 | Cell. Physiol. Biochem. | pmid:24977488 |
| Fayyaz S et al. | Divergent role of sphingosine 1-phosphate on insulin resistance. | 2014 | Cell. Physiol. Biochem. | pmid:24977487 |
| Fukumoto K et al. | Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment. | 2014 | Behav. Brain Res. | pmid:24713151 |
| Halmer R et al. | Sphingolipids: important players in multiple sclerosis. | 2014 | Cell. Physiol. Biochem. | pmid:24977485 |
| Laroni A et al. | Safety of the first dose of fingolimod for multiple sclerosis: results of an open-label clinical trial. | 2014 | BMC Neurol | pmid:24690227 |
| Tarbell JM et al. | Mechanosensing at the vascular interface. | 2014 | Annu Rev Biomed Eng | pmid:24905872 |
| Potì F et al. | Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). | 2014 | Cardiovasc. Res. | pmid:24891400 |
| Chawla S et al. | Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. | 2014 | PLoS ONE | pmid:24887065 |
| Wollenberg A et al. | Immunological and molecular targets of atopic dermatitis treatment. | 2014 | Br. J. Dermatol. | pmid:24720588 |
| Silveira-Dorta G et al. | Direct stereoselective synthesis of enantiomerically pure anti-β-amino alcohols. | 2014 | J. Org. Chem. | pmid:24708186 |
| Bunn PT et al. | Tissue requirements for establishing long-term CD4+ T cell-mediated immunity following Leishmania donovani infection. | 2014 | J. Immunol. | pmid:24634490 |
| Tanaka K et al. | Individual profiles of free ceramide species and the constituent ceramide species of sphingomyelin and neutral glycosphingolipid and their alteration according to the sequential changes of environmental oxygen content in human colorectal cancer Caco-2 cells. | 2014 | Glycoconj. J. | pmid:24310545 |
| Kubota D et al. | Proteomics identified overexpression of SET oncogene product and possible therapeutic utility of protein phosphatase 2A in alveolar soft part sarcoma. | 2014 | J. Proteome Res. | pmid:24621013 |
| Giovannoni G and Naismith RT | Natalizumab to fingolimod washout in patients at risk of PML: when good intentions yield bad outcomes. | 2014 | Neurology | pmid:24610331 |
| Zhang GQ et al. | Sphingosine-1-phosphate receptors respond differently to early myocardial ischemia and ischemia-reperfusion in vivo. | 2014 | Sheng Li Xue Bao | pmid:24777407 |
| Jokubaitis VG et al. | Fingolimod after natalizumab and the risk of short-term relapse. | 2014 | Neurology | pmid:24610329 |
| Mahajan-Thakur S et al. | Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. | 2014 | J. Leukoc. Biol. | pmid:24990321 |
| Kondo S et al. | Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development. | 2014 | PLoS ONE | pmid:24714781 |
| Korbelik M et al. | Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: cell surface exposure. | 2014 | Int. Immunopharmacol. | pmid:24713544 |
| Gatfield J et al. | Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling. | 2014 | Cell. Signal. | pmid:24704119 |
| Zhang J and Song J | Amphiphilic degradable polymers for immobilization and sustained delivery of sphingosine 1-phosphate. | 2014 | Acta Biomater | pmid:24631657 |
| Priceman SJ et al. | S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3. | 2014 | Cell Rep | pmid:24630990 |
| Wang G et al. | The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction. | 2014 | J. Cardiovasc. Pharmacol. | pmid:24508946 |
| Sato DK et al. | Changes in Th17 and regulatory T cells after fingolimod initiation to treat multiple sclerosis. | 2014 | J. Neuroimmunol. | pmid:24507619 |
| Hagihara K et al. | FTY720 stimulated ROS generation and the Sty1/Atf1 signaling pathway in the fission yeast Schizosaccharomyces pombe. | 2014 | Genes Cells | pmid:24506481 |
| Lu L et al. | Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage. | 2014 | Brain Res. | pmid:24502984 |
| Mezzar S et al. | RP-HPLC-fluorescence analysis of aliphatic aldehydes: application to aldehyde-generating enzymes HACL1 and SGPL1. | 2014 | J. Lipid Res. | pmid:24323699 |
| Swinnen E et al. | The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. | 2014 | Mol. Biol. Cell | pmid:24196832 |
| Czubowicz K and Strosznajder R | Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate. | 2014 | Mol. Neurobiol. | pmid:24420784 |
| Di Benedetto R et al. | Protected sphingosine from phytosphingosine as an efficient acceptor in glycosylation reaction. | 2014 | Org. Lett. | pmid:24428384 |
| Pennisi E | Ecology. Parasitic puppeteers begin to yield their secrets. | 2014 | Science | pmid:24436399 |
| Anthony DC et al. | Investigation of immune and CNS-mediated effects of fingolimod in the focal delayed-type hypersensitivity multiple sclerosis model. | 2014 | Neuropharmacology | pmid:24412675 |
| Chuang WL et al. | Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients. | 2014 | Mol. Genet. Metab. | pmid:24418695 |
| Mendes-Braz M et al. | The effects of glucose and lipids in steatotic and non-steatotic livers in conditions of partial hepatectomy under ischaemia-reperfusion. | 2014 | Liver Int. | pmid:24107124 |
| Buddaseth S et al. | Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod). | 2014 | Cancer Biol. Ther. | pmid:24335183 |
| Voon V et al. | Fingolimod-induced atrioventricular conduction defects in a young lady with multiple sclerosis--insights into possible drug mechanism. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24309839 |
| Gold R et al. | Assessment of cardiac safety during fingolimod treatment initiation in a real-world relapsing multiple sclerosis population: a phase 3b, open-label study. | 2014 | J. Neurol. | pmid:24221641 |
| Wu YF et al. | First total synthesis of ganglioside DSG-A possessing neuritogenic activity. | 2014 | Org. Biomol. Chem. | pmid:25338766 |
| Tuuf J and Mattjus P | Membranes and mammalian glycolipid transferring proteins. | 2014 | Chem. Phys. Lipids | pmid:24220498 |
| Hutchinson M et al. | Efficacy and safety of BG-12 (dimethyl fumarate) and other disease-modifying therapies for the treatment of relapsing-remitting multiple sclerosis: a systematic review and mixed treatment comparison. | 2014 | Curr Med Res Opin | pmid:24195574 |
| Spinedi A | Brefeldin A limits N-hexanoylsphingosine-induced accumulation of natural ceramide via the salvage pathway by enhancing glucosylation. | 2014 | Lipids | pmid:24194457 |
| Farhat M et al. | Reversion of apoptotic resistance of TP53-mutated Burkitt lymphoma B-cells to spindle poisons by exogenous activation of JNK and p38 MAP kinases. | 2014 | Cell Death Dis | pmid:24787013 |
| Wang XQ et al. | Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway. | 2014 | Prostaglandins Other Lipid Mediat. | pmid:24614064 |
| Kondo N et al. | Identification of the phytosphingosine metabolic pathway leading to odd-numbered fatty acids. | 2014 | Nat Commun | pmid:25345524 |
| Fincher J et al. | G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate. | 2014 | Dev. Neurosci. | pmid:25138637 |
| Cencetti F et al. | Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. | 2014 | FEBS J. | pmid:25131845 |
| Francis G et al. | Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy. | 2014 | Mult. Scler. | pmid:23950550 |
| Neuber C et al. | Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry. | 2014 | Anal. Chem. | pmid:25137547 |
| Nagahashi M et al. | Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. | 2014 | Adv Biol Regul | pmid:24210073 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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