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Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. |
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PLoS ONE |
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Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle sphingolipid synthesis in offspring hamsters fed a high-fat diet. |
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Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. |
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Serum Metabonomics of Mild Acute Pancreatitis. |
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Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. |
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Cell Transplant |
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Mol Med Rep |
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Pathog Dis |
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PLoS ONE |
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Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate. |
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Cell Chem Biol |
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Sci Rep |
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Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. |
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Sci Rep |
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Altered T cell phenotypes associated with clinical relapse of multiple sclerosis patients receiving fingolimod therapy. |
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Sci Rep |
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Mediators Inflamm. |
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Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. |
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S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. |
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IUBMB Life |
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Platelets |
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Sci Rep |
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Expert Opin Ther Pat |
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The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. |
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Invest. Ophthalmol. Vis. Sci. |
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Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. |
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PLoS ONE |
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Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. |
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Oxid Med Cell Longev |
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Sci Rep |
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Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. |
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Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response. |
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Physiol Rep |
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Oncotarget |
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FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. |
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Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. |
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Biosci. Biotechnol. Biochem. |
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Complete structural characterization of ceramides as [M-H]- ions by multiple-stage linear ion trap mass spectrometry. |
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Biochimie |
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Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma. |
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Oncotarget |
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Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. |
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Biochim. Biophys. Acta |
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Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. |
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Langmuir |
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