sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Surya VN et al. Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. 2016 J R Soc Interface pmid:27974574
Soltau I et al. Serum-Sphingosine-1-Phosphate Concentrations Are Inversely Associated with Atherosclerotic Diseases in Humans. 2016 PLoS ONE pmid:27973607
Kasbi-Chadli F et al. Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle sphingolipid synthesis in offspring hamsters fed a high-fat diet. 2016 Eur J Nutr pmid:25787885
Stolwijk JA et al. Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function. 2016 J. Biol. Chem. pmid:27624938
Steiner R et al. Elucidating the chemical structure of native 1-deoxysphingosine. 2016 J. Lipid Res. pmid:27165858
Chen W et al. Sphingosine 1-phosphate in metabolic syndrome (Review). 2016 Int. J. Mol. Med. pmid:27600830
Chen C et al. Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. 2016 Mol. Cell. Endocrinol. pmid:26948947
Xu H et al. Serum Metabonomics of Mild Acute Pancreatitis. 2016 J. Clin. Lab. Anal. pmid:27169745
Adamiak M et al. Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. 2016 Cell Transplant pmid:27412411
Liu X et al. ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. 2016 J. Physiol. Biochem. pmid:27377933
Egom EE et al. Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. 2016 Mol. Cell. Biochem. pmid:27372350
Sanagawa A et al. Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. 2016 Mol Med Rep pmid:27357063
Tiper IV et al. Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. 2016 Pathog Dis pmid:27354294
Zhang XE et al. Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. 2016 PLoS ONE pmid:27187066
Ohtoyo M et al. Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate. 2016 Cell Chem Biol pmid:27185637
Tong S et al. Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. 2016 J. Biol. Chem. pmid:27405756
Mi JN et al. New Immunosuppressive Sphingoid Base and Ceramide Analogues in Wild Cordyceps. 2016 Sci Rep pmid:27966660
Trinh HK et al. Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. 2016 Sci Rep pmid:27830727
Fujii C et al. Altered T cell phenotypes associated with clinical relapse of multiple sclerosis patients receiving fingolimod therapy. 2016 Sci Rep pmid:27752051
Pyne S et al. Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances. 2016 Prog. Lipid Res. pmid:26970273
Aoki M et al. Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential. 2016 Mediators Inflamm. pmid:26966342
Brinck JW et al. Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. 2016 Arterioscler. Thromb. Vasc. Biol. pmid:26966278
Chawla S et al. S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. 2016 IUBMB Life pmid:26959531
Vito CD et al. Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications. 2016 Platelets pmid:26950429
Jin J et al. Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate. 2016 Sci Rep pmid:26948042
Guerrero M et al. Sphingosine 1-phosphate receptor 1 agonists: a patent review (2013-2015). 2016 Expert Opin Ther Pat pmid:26947494
Kim SE et al. The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. 2016 Invest. Ophthalmol. Vis. Sci. pmid:26830367
Messias CV et al. Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. 2016 PLoS ONE pmid:26824863
Pászti-Gere E et al. Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. 2016 Oxid Med Cell Longev pmid:26823955
Wiltshire R et al. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. 2016 Sci Rep pmid:26813587
Farez MF and Correale J Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. 2016 J. Neurol. Sci. pmid:26810518
Xu R et al. Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response. 2016 Oncotarget pmid:26943039
Fan A et al. Liver X receptor-α and miR-130a-3p regulate expression of sphingosine 1-phosphate receptor 2 in human umbilical vein endothelial cells. 2016 Am. J. Physiol., Cell Physiol. pmid:26669941
Petrache I and Berdyshev EV Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. 2016 Annu. Rev. Physiol. pmid:26667073
Bohannon JK and Sherwood ER Editorial: Feeling the burn: sphingolipids and infection risk after thermal injury. 2016 J. Leukoc. Biol. pmid:27909176
Im J et al. Desensitization of idiopathic pulmonary fibrosis fibroblasts to Alternaria alternata extract-mediated necrotic cell death. 2016 Physiol Rep pmid:27905295
Hoehn RS et al. Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut. 2016 Cell. Physiol. Biochem. pmid:27607915
Neubauer HA et al. An oncogenic role for sphingosine kinase 2. 2016 Oncotarget pmid:27588496
Nagahashi M et al. DNA damage response and sphingolipid signaling in liver diseases. 2016 Surg. Today pmid:26514817
Tavakoli Tabazavareh S et al. Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis. 2016 Cell. Physiol. Biochem. pmid:27184795
Ohtoyo M et al. Scintillation Proximity Assay to Detect the Changes in Cellular Dihydrosphingosine 1-Phosphate Levels. 2016 Lipids pmid:27585475
Kalhori V et al. FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. 2016 Endocr. Relat. Cancer pmid:26935838
Liu X et al. Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. 2016 Exp. Biol. Med. (Maywood) pmid:26376826
Gowda SG et al. Highly efficient preparation of sphingoid bases from glucosylceramides by chemoenzymatic method. 2016 J. Lipid Res. pmid:26667669
Lee WJ et al. Inhibitory effects of N,N,N-trimethyl phytosphingosine-iodide on melanogenesis via ERK activation-mediated MITF degradation. 2016 Biosci. Biotechnol. Biochem. pmid:26263195
Hsu FF Complete structural characterization of ceramides as [M-H]- ions by multiple-stage linear ion trap mass spectrometry. 2016 Biochimie pmid:27523779
Grammatikos G et al. Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma. 2016 Oncotarget pmid:26933996
Wirrig C et al. Sphingosylphosphorylcholine inhibits macrophage adhesion to vascular smooth muscle cells. 2016 Biochem. Pharmacol. pmid:27402344
Filipenko I et al. Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. 2016 Biochim. Biophys. Acta pmid:27616330
Stahlberg S et al. Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. 2016 Langmuir pmid:26828109