|
|
|
|
pmid:
|
Tokuda H et al. |
Extracellular sphingomyelinase induces interleukin-6 synthesis in osteoblasts. |
1999 |
J. Cell. Biochem. |
pmid:10022508
|
Tolleson WH et al. |
Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. |
1999 |
Int. J. Oncol. |
pmid:10200332
|
Chen N et al. |
Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis. |
1999 |
J. Biol. Chem. |
pmid:10336426
|
Yang L et al. |
Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors. |
1999 |
J. Biochem. |
pmid:10393324
|
Yoon HT et al. |
Improved fluorescent determination method of cellular sphingoid bases in high-performance liquid chromatography. |
1999 |
Arch. Pharm. Res. |
pmid:10403133
|
Turner PC et al. |
Fumonisin contamination of food: progress in development of biomarkers to better assess human health risks. |
1999 |
Mutat. Res. |
pmid:10415433
|
Tedesco MM and Matile S |
Spectroscopic detection of endovesiculation by large unilamellar phosphatidylcholine vesicles: effects of chlorpromazine, dibucaine, and safingol. |
1999 |
Bioorg. Med. Chem. |
pmid:10465411
|
Touyz RM and Schiffrin EL |
Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. |
1999 |
Hypertension |
pmid:10523394
|
Grilley MM and Takemoto JY |
Assay of the Saccharomyces cerevisiae dihydrosphingosine C-4 hydroxylase. |
2000 |
Meth. Enzymol. |
pmid:10563305
|
Lynch DV |
Enzymes of sphingolipid metabolism in plants. |
2000 |
Meth. Enzymol. |
pmid:10563318
|
Riley RT and Plattner RD |
Fermentation, partial purification, and use of serine palmitoyltransferase inhibitors from Isaria (= Cordyceps) sinclairii. |
2000 |
Meth. Enzymol. |
pmid:10563339
|
Bielawska A et al. |
Radiolabeling of the sphingolipid backbone. |
2000 |
Meth. Enzymol. |
pmid:10563345
|
Sonnino S et al. |
Preparation of radioactive gangliosides, 3H or 14C isotopically labeled at oligosaccharide or ceramide moieties. |
2000 |
Meth. Enzymol. |
pmid:10563353
|
Castro AF et al. |
Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers. |
1999 |
Biochem. Pharmacol. |
pmid:10571246
|
Xu K and Thornalley PJ |
Antitumour activity of sphingoid base adducts of phenethyl isothiocyanate. |
2000 |
Bioorg. Med. Chem. Lett. |
pmid:10636242
|
Nowak DM et al. |
Sphingosine and sphinganine levels in human mesothelial cells in vitro as a potential index of signal transduction pathways impacted by microbes and osmolality. |
1998 |
Adv Perit Dial |
pmid:10649716
|
van der Westhuizen L et al. |
Sphinganine/sphingosine ratio in plasma and urine as a possible biomarker for fumonisin exposure in humans in rural areas of Africa. |
1999 |
Food Chem. Toxicol. |
pmid:10654591
|
Sharma C et al. |
Inhibition of Ca2+ release channel (ryanodine receptor) activity by sphingolipid bases: mechanism of action. |
2000 |
Chem. Phys. Lipids |
pmid:10660207
|
Jarvis WD and Grant S |
Protein kinase C targeting in antineoplastic treatment strategies. |
1999 |
Invest New Drugs |
pmid:10665476
|
Niwa M et al. |
Tumor necrosis factor-alpha-mediated signal transduction in human neutrophils: involvement of sphingomyelin metabolites in the priming effect of TNF-alpha on the fMLP-stimulated superoxide production. |
2000 |
Life Sci. |
pmid:10666000
|
Bodennec J et al. |
Purification of free sphingoid bases by solid-phase extraction on weak cation exchanger cartridges. |
2000 |
Anal. Biochem. |
pmid:10706795
|
Perry DK et al. |
Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis. |
2000 |
J. Biol. Chem. |
pmid:10722759
|
Brandwagt BF et al. |
A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin B1. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10781105
|
Smith GW et al. |
Sequence of cardiovascular changes leading to pulmonary edema in swine fed culture material containing fumonisin. |
1999 |
Am. J. Vet. Res. |
pmid:10791944
|
Zanolari B et al. |
Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. |
2000 |
EMBO J. |
pmid:10856228
|
Smith GW et al. |
Purified fumonisin B(1) decreases cardiovascular function but does not alter pulmonary capillary permeability in swine. |
2000 |
Toxicol. Sci. |
pmid:10869473
|
Mao C et al. |
Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide. |
2000 |
J. Biol. Chem. |
pmid:10900202
|
Bodennec J et al. |
Differential labelling of sphingolipids by [3H]serine and ([3H]methyl)-methionine in fish leukocytes. |
2000 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:10904865
|
Bose R and Kolesnick R |
Measurement of ceramide synthase activity. |
2000 |
Meth. Enzymol. |
pmid:10914032
|
Kwon OS et al. |
Biochemical and morphological effects of fumonisin B(1) on primary cultures of rat cerebrum. |
2000 Jul-Aug |
Neurotoxicol Teratol |
pmid:10974595
|
van der Westhuizen L et al. |
The effect of a single gavage dose of fumonisin B(1) on the sphinganine and sphingosine levels in vervet monkeys. |
2001 Feb-Mar |
Toxicon |
pmid:10978745
|
Amin HM et al. |
Characterization of apoptosis induced by protein kinase C inhibitors and its modulation by the caspase pathway in acute promyelocytic leukaemia. |
2000 |
Br. J. Haematol. |
pmid:10997964
|
Carratù MR et al. |
Prenatal exposure model simulating CO inhalation in human cigarette smokers: sphingomyelin alterations in the rat sciatic nerve. |
2000 |
Toxicol. Lett. |
pmid:11033239
|
Henry MH et al. |
The toxicity of purified fumonisin B1 in broiler chicks. |
2000 |
Poult. Sci. |
pmid:11055840
|
Jenkins GM and Hannun YA |
Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae. |
2001 |
J. Biol. Chem. |
pmid:11056159
|
Merrill AH et al. |
Analysis of sphingoid bases and sphingoid base 1-phosphates by high-performance liquid chromatography. |
2000 |
Meth. Enzymol. |
pmid:11070857
|
Bodennec J et al. |
Purification of sphingolipid classes by solid-phase extraction with aminopropyl and weak cation exchanger cartridges. |
2000 |
Meth. Enzymol. |
pmid:11070865
|
Kawamura A et al. |
Use of circular dichroism for assigning stereochemistry of sphingosine and other long-chain bases. |
2000 |
Meth. Enzymol. |
pmid:11070875
|
Wu WI and Carman GM |
Kinetic analysis of sphingoid base inhibition of yeast phosphatidate phosphatase. |
2000 |
Meth. Enzymol. |
pmid:11070885
|
Scott RH et al. |
Synthesis and use of caged sphingolipids. |
2000 |
Meth. Enzymol. |
pmid:11070887
|
Guillas I et al. |
Analysis of ceramides present in glycosylphosphatidylinositol anchored proteins of Saccharomyces cerevisiae. |
2000 |
Meth. Enzymol. |
pmid:11070898
|
Maurer BJ et al. |
Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism. |
2000 |
J. Natl. Cancer Inst. |
pmid:11106681
|
Tamama K et al. |
Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells. |
2001 |
Biochem. J. |
pmid:11115407
|
Hsu FF and Turk J |
Structural determination of glycosphingolipids as lithiated adducts by electrospray ionization mass spectrometry using low-energy collisional-activated dissociation on a triple stage quadrupole instrument. |
2001 |
J. Am. Soc. Mass Spectrom. |
pmid:11142362
|
Tamura K et al. |
Cloning and characterization of a cDNA encoding serine palmitoyltransferase in Arabidopsis thaliana. |
2000 |
Biochem. Soc. Trans. |
pmid:11171191
|
Dasgupta S and Hogan EL |
Chromatographic resolution and quantitative assay of CNS tissue sphingoids and sphingolipids. |
2001 |
J. Lipid Res. |
pmid:11181761
|
van der Westhuizen L et al. |
The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. |
2001 |
Toxicon |
pmid:11223085
|
Ziulkoski AL et al. |
De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11237757
|
Senchenkov A et al. |
Targeting ceramide metabolism--a strategy for overcoming drug resistance. |
2001 |
J. Natl. Cancer Inst. |
pmid:11238696
|
Venkataraman K and Futerman AH |
Comparison of the metabolism of L-erythro- and L-threo-sphinganines and ceramides in cultured cells and in subcellular fractions. |
2001 |
Biochim. Biophys. Acta |
pmid:11239824
|
Mathur S et al. |
Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. |
2001 |
Toxicol. Sci. |
pmid:11248151
|
Mathur S et al. |
Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. |
2001 |
Toxicol. Sci. |
pmid:11248152
|
Sharma RP et al. |
Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1. |
2001 |
Toxicology |
pmid:11250056
|
Blaukat A and Dikic I |
Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. |
2001 |
Biol. Chem. |
pmid:11258664
|
Carlson DB et al. |
Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. |
2001 |
Toxicol. Appl. Pharmacol. |
pmid:11264020
|
Thurman RG et al. |
SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat. |
1994 |
Transpl. Int. |
pmid:11271195
|
El Bawab S et al. |
Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. |
2001 |
J. Biol. Chem. |
pmid:11278489
|
Kodell RL et al. |
A mechanistic approach to modelling the risk of liver tumours in mice exposed to fumonisin B1 in the diet. |
2001 |
Food Addit Contam |
pmid:11304033
|
Delongchamp RR and Young JF |
Tissue sphinganine as a biomarker of fumonisin-induced apoptosis. |
2001 |
Food Addit Contam |
pmid:11304034
|
Qiu M and Liu X |
Determination of sphinganine, sphingosine and Sa/So ratio in urine of humans exposed to dietary fumonisin B1. |
2001 |
Food Addit Contam |
pmid:11304035
|
van der Westhuizen L et al. |
The effect of a single gavage dose of fumonisin B(2) on the sphinganine and sphingosine concentrations in vervet monkeys. |
2001 |
Food Chem. Toxicol. |
pmid:11313111
|
Solfrizzo M et al. |
Ineffectiveness of activated carbon in reducing the alteration of sphingolipid metabolism in rats exposed to fumonisin-contaminated diets. |
2001 |
Food Chem. Toxicol. |
pmid:11313118
|
Abe M et al. |
Yeast 1,3-beta-glucan synthase activity is inhibited by phytosphingosine localized to the endoplasmic reticulum. |
2001 |
J. Biol. Chem. |
pmid:11337502
|
Ribar S et al. |
High-performance liquid chromatographic determination of sphinganine and sphingosine in serum and urine of subjects from an endemic nephropathy area in Croatia. |
2001 |
J. Chromatogr. B Biomed. Sci. Appl. |
pmid:11339295
|
Yu CH et al. |
Differential effects of fumonisin B1 on cell death in cultured cells: the significance of the elevated sphinganine. |
2001 |
Arch. Pharm. Res. |
pmid:11339633
|
Baek MY et al. |
Sphingolipid metabolic changes during chiral C2-ceramides induced apoptosis in human leukemia cells. |
2001 |
Arch. Pharm. Res. |
pmid:11339634
|
Sylvia VL et al. |
Regulation of phospholipase D (PLD) in growth plate chondrocytes by 24R,25-(OH)2D3 is dependent on cell maturation state (resting zone cells) and is specific to the PLD2 isoform. |
2001 |
Biochim. Biophys. Acta |
pmid:11341968
|
Haschek WM et al. |
Fumonisin toxicosis in swine: an overview of porcine pulmonary edema and current perspectives. |
2001 |
Environ. Health Perspect. |
pmid:11359693
|
Gelderblom WC et al. |
Toxicity of culture material of Fusarium verticillioides strain MRC 826 to nonhuman primates. |
2001 |
Environ. Health Perspect. |
pmid:11359695
|
Merrill AH et al. |
Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. |
2001 |
Environ. Health Perspect. |
pmid:11359697
|
Riley RT et al. |
Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. |
2001 |
Environ. Health Perspect. |
pmid:11359699
|
Sperling P et al. |
Functional identification of a delta8-sphingolipid desaturase from Borago officinalis. |
2001 |
Arch. Biochem. Biophys. |
pmid:11368168
|
Bailly JD et al. |
Toxicity of Fusarium moniliforme culture material containing known levels of fumonisin B1 in ducks. |
2001 |
Toxicology |
pmid:11376861
|
Guillas I et al. |
C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. |
2001 |
EMBO J. |
pmid:11387200
|
Dyatlovitskaya EV et al. |
Sphinganine in sphingomyelins of tumors and mouse regenerating liver. |
2001 |
Biochemistry Mosc. |
pmid:11405884
|
Osawa Y et al. |
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. |
2001 |
J. Immunol. |
pmid:11418646
|
Radin NS |
Apoptotic death by ceramide: will the real killer please stand up? |
2001 |
Med. Hypotheses |
pmid:11421634
|
Chang HC et al. |
Role of AKT kinase in sphingosine-induced apoptosis in human hepatoma cells. |
2001 |
J. Cell. Physiol. |
pmid:11424085
|
Wang H et al. |
N-(4-hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase. |
2001 |
Cancer Res. |
pmid:11431347
|
He Q et al. |
Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition. |
2001 |
Toxicol. Appl. Pharmacol. |
pmid:11437650
|
Boujaoude LC et al. |
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. |
2001 |
J. Biol. Chem. |
pmid:11443135
|
Masur K et al. |
High PKC alpha and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells. |
2001 |
Mol. Biol. Cell |
pmid:11451996
|
Chung N et al. |
Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae. |
2001 |
J. Biol. Chem. |
pmid:11468289
|
Liu H et al. |
Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. |
2001 |
J. Agric. Food Chem. |
pmid:11513718
|
Bhandari N et al. |
Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. |
2001 |
Toxicology |
pmid:11522378
|
Garren L et al. |
The induction and persistence of altered sphingolipid biosynthesis in rats treated with fumonisin B1. |
2001 |
Food Addit Contam |
pmid:11552753
|
Ito Y et al. |
Structural requirements of sphingosine molecules for inhibition of DNA primase: biochemical and computational analyses. |
2001 |
Biochemistry |
pmid:11560507
|
Abnet CC et al. |
A cross-sectional study of human serum sphingolipids, diet and physiologic parameters. |
2001 |
J. Nutr. |
pmid:11584099
|
Kim MS et al. |
Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. |
2001 |
Toxicol. Appl. Pharmacol. |
pmid:11601888
|
Solfrizzo M et al. |
In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins. |
2001 |
Mycopathologia |
pmid:11678589
|
Linn SC et al. |
Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption. |
2001 |
Biochem. Soc. Trans. |
pmid:11709083
|
Abnet CC et al. |
Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. |
2001 |
Cancer Causes Control |
pmid:11714110
|
Tamura K et al. |
Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis. |
2001 |
Plant Cell Physiol. |
pmid:11726713
|
Galvano F et al. |
DNA damage in human fibroblasts exposed to fumonisin B(1). |
2002 |
Food Chem. Toxicol. |
pmid:11731033
|
Alemany R et al. |
Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate. |
2001 |
FEBS Lett. |
pmid:11741596
|
Benaud C et al. |
Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase. |
2002 |
J. Biol. Chem. |
pmid:11792696
|
|
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). |
2001 |
Natl Toxicol Program Tech Rep Ser |
pmid:11852482
|
da Rocha AB et al. |
Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas? |
2002 |
Oncologist |
pmid:11854544
|
Diatlovitskaia EV |
[Biologically effective sphingolipids devoid of 4-trans-double bond in the sphingoid hydrocarbon chain]. |
2002 Jan-Feb |
Bioorg. Khim. |
pmid:11875973
|