3-Ketosphinganine

3-Ketosphinganine is a lipid of Sphingolipids (SP) class. The involved functions are known as Anabolism and establishment and maintenance of localization. 3-ketosphinganine often locates in Membrane and membrane raft.

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Introduction

To understand associated biological information of 3-Ketosphinganine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 3-Ketosphinganine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-Ketosphinganine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-Ketosphinganine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 3-Ketosphinganine

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Authors Title Published Journal PubMed Link
pmid:
Williams RD et al. Enzymology of long-chain base synthesis by liver: characterization of serine palmitoyltransferase in rat liver microsomes. 1984 Arch. Biochem. Biophys. pmid:6421234
Radin NS Biosynthesis of the sphingoid bases: a provocation. 1984 J. Lipid Res. pmid:6442338
Messmer TO et al. Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. 1989 J. Nutr. pmid:2495341
Chigorno V et al. Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture. 1997 J. Lipid Res. pmid:9215544
Dickson RC et al. Serine palmitoyltransferase. 2000 Meth. Enzymol. pmid:10563304
Gable K et al. Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity. 2000 J. Biol. Chem. pmid:10713067
Hanada K et al. D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis. 2000 FEBS Lett. pmid:10828452
Hanada K et al. Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques. 2000 J. Biol. Chem. pmid:10722674
Tamura K et al. Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis. 2001 Plant Cell Physiol. pmid:11726713