3-Ketosphinganine

3-Ketosphinganine is a lipid of Sphingolipids (SP) class. The involved functions are known as Anabolism and establishment and maintenance of localization. 3-ketosphinganine often locates in Membrane and membrane raft.

Cross Reference

Introduction

To understand associated biological information of 3-Ketosphinganine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 3-Ketosphinganine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-Ketosphinganine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 3-Ketosphinganine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 3-Ketosphinganine

Download all related citations
Per page 10 20 50 | Total 46
Authors Title Published Journal PubMed Link
Ordóñez YF et al. 3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells. 2016 Mol Biosyst pmid:26928714
Ejsing CS et al. Quantitative Profiling of Long-Chain Bases by Mass Tagging and Parallel Reaction Monitoring. 2015 PLoS ONE pmid:26660097
Chao DY et al. Sphingolipids in the root play an important role in regulating the leaf ionome in Arabidopsis thaliana. 2011 Plant Cell pmid:21421810
Nimrichter L and Rodrigues ML Fungal glucosylceramides: from structural components to biologically active targets of new antimicrobials. 2011 Front Microbiol pmid:22025918
Uchida Y The role of fatty acid elongation in epidermal structure and function. 2011 Dermatoendocrinol pmid:21695014
Bauerly K et al. Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. 2011 PLoS ONE pmid:21814553
Momin AA et al. A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. 2011 J. Lipid Res. pmid:21415121
BÅ‚achnio-Zabielska A et al. Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity. 2011 Lipids pmid:21181285
Merrill AH Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. 2011 Chem. Rev. pmid:21942574
Koeller CM and Heise N The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease. 2011 Enzyme Res pmid:21603271
Nissimov JI et al. Draft genome sequence of the coccolithovirus EhV-84. 2011 Stand Genomic Sci pmid:22180805
Grimm MO et al. Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease. 2011 Int J Alzheimers Dis pmid:21660213
Loewith R and Hall MN Target of rapamycin (TOR) in nutrient signaling and growth control. 2011 Genetics pmid:22174183
Schmitz-Peiffer C Targeting ceramide synthesis to reverse insulin resistance. 2010 Diabetes pmid:20876726
Raman MC et al. The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein. 2010 Biopolymers pmid:20578000
Sims K et al. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. 2010 J. Biol. Chem. pmid:20876532
Chen Y et al. An introduction to sphingolipid metabolism and analysis by new technologies. 2010 Neuromolecular Med. pmid:20680704
Liu Y et al. Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. 2010 Mol. Cancer pmid:20624317
Sweeley CC Reflections on my career in analytical chemistry and biochemistry. 2010 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:20948176
Arana L et al. Ceramide and ceramide 1-phosphate in health and disease. 2010 Lipids Health Dis pmid:20137073
Park H et al. Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. 2010 J. Lipid Res. pmid:19786568
Bahtiar A et al. Identification of a novel L-serine analog that suppresses osteoclastogenesis in vitro and bone turnover in vivo. 2009 J. Biol. Chem. pmid:19837662
Ikushiro H et al. Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum. 2009 J. Biochem. pmid:19564159
Seamen E et al. P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. 2009 PLoS Genet. pmid:19662161
Song WQ et al. Characterization of two cotton cDNAs encoding trans-2-enoyl-CoA reductase reveals a putative novel NADPH-binding motif. 2009 J. Exp. Bot. pmid:19286916
Gupta SD et al. Tsc10p and FVT1: topologically distinct short-chain reductases required for long-chain base synthesis in yeast and mammals. 2009 J. Lipid Res. pmid:19141869
Pruett ST et al. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols. 2008 J. Lipid Res. pmid:18499644
Ikushiro H et al. Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii. 2007 J. Bacteriol. pmid:17557831
Fornarotto M et al. Sphingolipid biosynthesis in pathogenic fungi: identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus. 2006 Biochim. Biophys. Acta pmid:16431155
Merrill AH et al. Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. 2005 Methods pmid:15894491
Yi H et al. Direct evidence for the function of FUM13 in 3-ketoreduction of mycotoxin fumonisins in Fusarium verticillioides. 2005 J. Agric. Food Chem. pmid:15969533
Acharya U and Acharya JK Enzymes of sphingolipid metabolism in Drosophila melanogaster. 2005 Cell. Mol. Life Sci. pmid:15666085
Verhoeven K et al. SPTLC1 mutation in twin sisters with hereditary sensory neuropathy type I. 2004 Neurology pmid:15037712
Monaghan E et al. Mutations in the Lcb2p subunit of serine palmitoyltransferase eliminate the requirement for the TSC3 gene in Saccharomyces cerevisiae. 2002 Yeast pmid:12185836
Linn SC et al. Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption. 2001 Biochem. Soc. Trans. pmid:11709083
Tamura K et al. Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis. 2001 Plant Cell Physiol. pmid:11726713
Ardail D et al. Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria. 2001 FEBS Lett. pmid:11163764
Dickson RC et al. Serine palmitoyltransferase. 2000 Meth. Enzymol. pmid:10563304
Gable K et al. Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity. 2000 J. Biol. Chem. pmid:10713067
Hanada K et al. D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis. 2000 FEBS Lett. pmid:10828452
Hanada K et al. Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques. 2000 J. Biol. Chem. pmid:10722674
Chigorno V et al. Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture. 1997 J. Lipid Res. pmid:9215544
Messmer TO et al. Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. 1989 J. Nutr. pmid:2495341
Williams RD et al. Enzymology of long-chain base synthesis by liver: characterization of serine palmitoyltransferase in rat liver microsomes. 1984 Arch. Biochem. Biophys. pmid:6421234
Radin NS Biosynthesis of the sphingoid bases: a provocation. 1984 J. Lipid Res. pmid:6442338
pmid: