3-Ketosphinganine

3-Ketosphinganine is a lipid of Sphingolipids (SP) class. The involved functions are known as Anabolism and establishment and maintenance of localization. 3-ketosphinganine often locates in Membrane and membrane raft.

Cross Reference

Introduction

To understand associated biological information of 3-Ketosphinganine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 3-Ketosphinganine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-Ketosphinganine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 3-Ketosphinganine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 3-Ketosphinganine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 3-Ketosphinganine

Download all related citations
Per page 10 20 50 | Total 46
Authors Title Published Journal PubMed Link
pmid:
Williams RD et al. Enzymology of long-chain base synthesis by liver: characterization of serine palmitoyltransferase in rat liver microsomes. 1984 Arch. Biochem. Biophys. pmid:6421234
Linn SC et al. Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption. 2001 Biochem. Soc. Trans. pmid:11709083
Fornarotto M et al. Sphingolipid biosynthesis in pathogenic fungi: identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus. 2006 Biochim. Biophys. Acta pmid:16431155
Raman MC et al. The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein. 2010 Biopolymers pmid:20578000
Acharya U and Acharya JK Enzymes of sphingolipid metabolism in Drosophila melanogaster. 2005 Cell. Mol. Life Sci. pmid:15666085
Merrill AH Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. 2011 Chem. Rev. pmid:21942574
Uchida Y The role of fatty acid elongation in epidermal structure and function. 2011 Dermatoendocrinol pmid:21695014
Schmitz-Peiffer C Targeting ceramide synthesis to reverse insulin resistance. 2010 Diabetes pmid:20876726
Koeller CM and Heise N The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease. 2011 Enzyme Res pmid:21603271
Hanada K et al. D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis. 2000 FEBS Lett. pmid:10828452
Ardail D et al. Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria. 2001 FEBS Lett. pmid:11163764
Nimrichter L and Rodrigues ML Fungal glucosylceramides: from structural components to biologically active targets of new antimicrobials. 2011 Front Microbiol pmid:22025918
Loewith R and Hall MN Target of rapamycin (TOR) in nutrient signaling and growth control. 2011 Genetics pmid:22174183
Grimm MO et al. Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease. 2011 Int J Alzheimers Dis pmid:21660213
Yi H et al. Direct evidence for the function of FUM13 in 3-ketoreduction of mycotoxin fumonisins in Fusarium verticillioides. 2005 J. Agric. Food Chem. pmid:15969533
Ikushiro H et al. Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii. 2007 J. Bacteriol. pmid:17557831
Ikushiro H et al. Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum. 2009 J. Biochem. pmid:19564159
Bahtiar A et al. Identification of a novel L-serine analog that suppresses osteoclastogenesis in vitro and bone turnover in vivo. 2009 J. Biol. Chem. pmid:19837662
Hanada K et al. Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques. 2000 J. Biol. Chem. pmid:10722674