| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Sauro S et al. | Di-Calcium Phosphate and Phytosphingosine as an Innovative Acid-Resistant Treatment to Occlude Dentine Tubules. | Caries Res. | pmid:27179116 | |
| Pin D et al. | An emulsion restores the skin barrier by decreasing the skin pH and inflammation in a canine experimental model. | J. Comp. Pathol. | pmid:24975893 | |
| Bouhours D and Bouhours JF | Phytosphingosine in intestinal glycolipids of the rat fetus. | 1984 | Biochim. Biophys. Acta | pmid:6733126 |
| Li YT et al. | Isolation and characterization of a novel phytosphingosine-containing GM2 ganglioside from mullet roe (Mugil cephalus). | 1984 | J. Biol. Chem. | pmid:6746635 |
| Crossman MW and Hirschberg CB | Biosynthesis of 4D-hydroxysphinganine by the rat. En bloc incorporation of the sphinganine carbon backbone. | 1984 | Biochim. Biophys. Acta | pmid:6477953 |
| Radin NS | Biosynthesis of the sphingoid bases: a provocation. | 1984 | J. Lipid Res. | pmid:6442338 |
| Bouhours D and Bouhours JF | Developmental changes of the lipidic part of the neutral glycosphingolipids of the rat stomach. | 1985 | J. Biol. Chem. | pmid:3972786 |
| Nishimura K | Phytosphingosine is a characteristic component of the glycolipids in the vertebrate intestine. | 1987 | Comp. Biochem. Physiol., B | pmid:3829627 |
| Bouchon B et al. | Selective enrichment of phytosphingosine in glycosphingolipids of isolated human thyrocytes as compared to the whole thyroid. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3566758 |
| Merrill AH et al. | Quantitation of free sphingosine in liver by high-performance liquid chromatography. | 1988 | Anal. Biochem. | pmid:3407935 |
| Madison KC et al. | Sphingolipid metabolism in organotypic mouse keratinocyte cultures. | 1990 | J. Invest. Dermatol. | pmid:2123494 |
| Röder B et al. | The determination of phytosphingosine-containing globotriaosylceramide from human kidney in the presence of lactosylceramide. | 1990 | Chem. Phys. Lipids | pmid:2162261 |
| Pinto WJ et al. | Sphingolipid long-chain-base auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection. | 1992 | J. Bacteriol. | pmid:1556075 |
| Pinto WJ et al. | Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity. | 1992 | J. Bacteriol. | pmid:1556076 |
| Patton JL et al. | Phenotypes of sphingolipid-dependent strains of Saccharomyces cerevisiae. | 1992 | J. Bacteriol. | pmid:1429441 |
| Takamatsu K | Phytosphingosine-containing neutral glycosphingolipids and sulfatides in the human female genital tract: their association in the cervical epithelium and the uterine endometrium and their dissociation in the mucosa of fallopian tube with the menstrual cycle. | 1992 | Keio J Med | pmid:1434311 |
| Turinsky J and Nagel GW | Effect of sphingoid bases on basal and insulin-stimulated 2-deoxyglucose transport in skeletal muscle. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1417855 |
| Wu WI et al. | Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases. | 1993 | J. Biol. Chem. | pmid:8314751 |
| Zhao C et al. | Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. | 1994 | J. Biol. Chem. | pmid:8063782 |
| Haimovitz-Friedman A et al. | Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. | 1994 | J. Exp. Med. | pmid:8046331 |
| Quintans J et al. | Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8048941 |
| Gross SK et al. | Expression of glycosphingolipids in serum-free primary cultures of mouse kidney cells: male-female differences and androgen sensitivity. | 1994 | Mol. Cell. Biochem. | pmid:7845375 |
| Song Y et al. | Expression of new KDN-gangliosides in rainbow trout testis during spermatogenesis and their structural identification. | 1995 | Glycobiology | pmid:7540078 |
| Stewart ME and Downing DT | Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. | 1995 | J. Invest. Dermatol. | pmid:7561168 |
| Santana P et al. | Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. | 1996 | Cell | pmid:8706124 |
| Qie L et al. | Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids. | 1997 | J. Biol. Chem. | pmid:9195906 |
| Nagiec MM et al. | Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. | 1997 | J. Biol. Chem. | pmid:9092515 |
| Paukku T et al. | Novel cationic liposomes for DNA-transfection with high efficiency and low toxicity. | 1997 | Chem. Phys. Lipids | pmid:9219346 |
| Skrzypek MS et al. | Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae. | 1998 | J. Biol. Chem. | pmid:9446592 |
| Bodennec J et al. | Phytosphingosine biosynthesis differs from sphingosine in fish leukocytes and involves a transfer of methyl groups from [3H-methyl]methionine precursor. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9735337 |
| Lanterman MM and Saba JD | Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. | 1998 | Biochem. J. | pmid:9601083 |
| Jennemann R et al. | Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus. | 1999 | Eur. J. Biochem. | pmid:9914511 |
| Sharma C et al. | Inhibition of Ca2+ release channel (ryanodine receptor) activity by sphingolipid bases: mechanism of action. | 2000 | Chem. Phys. Lipids | pmid:10660207 |
| Grilley MM and Takemoto JY | Assay of the Saccharomyces cerevisiae dihydrosphingosine C-4 hydroxylase. | 2000 | Meth. Enzymol. | pmid:10563305 |
| Merrill AH et al. | Analysis of sphingoid bases and sphingoid base 1-phosphates by high-performance liquid chromatography. | 2000 | Meth. Enzymol. | pmid:11070857 |
| Wu WI and Carman GM | Kinetic analysis of sphingoid base inhibition of yeast phosphatidate phosphatase. | 2000 | Meth. Enzymol. | pmid:11070885 |
| Chung N and Obeid LM | Use of yeast as a model system for studies of sphingolipid metabolism and signaling. | 2000 | Meth. Enzymol. | pmid:10563337 |
| Chung N et al. | Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis. | 2000 | J. Biol. Chem. | pmid:10764732 |
| Azuma H et al. | Stereospecific total syntheses of sphingosine and its analogues from L-serine. | 2000 | J. Org. Chem. | pmid:10843643 |
| Zanolari B et al. | Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. | 2000 | EMBO J. | pmid:10856228 |
| Bodennec J et al. | Purification of free sphingoid bases by solid-phase extraction on weak cation exchanger cartridges. | 2000 | Anal. Biochem. | pmid:10706795 |
| He L et al. | A stereocontrolled, efficient synthetic route to bioactive sphingolipids: synthesis of phytosphingosine and phytoceramides from unsaturated ester precursors via cyclic sulfate intermediates. | 2000 | J. Org. Chem. | pmid:11076624 |
| Mao C et al. | Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide. | 2000 | J. Biol. Chem. | pmid:10900202 |
| Friant S et al. | Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. | 2001 | EMBO J. | pmid:11726514 |
| Chung N et al. | Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae. | 2001 | J. Biol. Chem. | pmid:11468289 |
| Jenkins GM and Hannun YA | Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae. | 2001 | J. Biol. Chem. | pmid:11056159 |
| Kang SS et al. | Cyclooxygenase-2 inhibitory cerebrosides from phytolaccae radix. | 2001 | Chem. Pharm. Bull. | pmid:11253924 |
| Yamada K et al. | Constituents of holothuroidea. 10. Isolation and structure of a biologically active ganglioside molecular species from the sea cucumber Holothuria leucospilota. | 2001 | Chem. Pharm. Bull. | pmid:11310672 |
| Ardail D et al. | Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria. | 2001 | FEBS Lett. | pmid:11163764 |
phytosphingosine
phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phytosphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phytosphingosine?
phytosphingosine is suspected in Infection, Nodule, Dehydration, Neuropathy, nervous system disorder, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phytosphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phytosphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phytosphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phytosphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phytosphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phytosphingosine?
Knock-out
Knock-out are used in the study 'Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.' (Jenkins GM and Hannun YA, 2001) and Knock-out are used in the study 'SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.' (Brace JL et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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