phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of phytosphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phytosphingosine?

phytosphingosine is suspected in Infection, Nodule, Dehydration, Neuropathy, nervous system disorder, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phytosphingosine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phytosphingosine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with phytosphingosine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with phytosphingosine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with phytosphingosine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phytosphingosine?

Knock-out

Knock-out are used in the study 'Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.' (Jenkins GM and Hannun YA, 2001) and Knock-out are used in the study 'SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.' (Brace JL et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with phytosphingosine

Download all related citations
Per page 10 20 50 100 | Total 330
Authors Title Published Journal PubMed Link
Schreiner S et al. Transcriptional activation of the adenoviral genome is mediated by capsid protein VI. 2012 PLoS Pathog. pmid:22427750
Carneiro P et al. Characterization of apoptosis-related oxidoreductases from Neurospora crassa. 2012 PLoS ONE pmid:22470547
Henry SA et al. Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. 2012 Genetics pmid:22345606
Fischer CL et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. 2012 Antimicrob. Agents Chemother. pmid:22155833
Kołaczkowska A et al. The regulatory inputs controlling pleiotropic drug resistance and hypoxic response in yeast converge at the promoter of the aminocholesterol resistance gene RTA1. 2012 FEMS Yeast Res. pmid:22129104
Lu Y et al. Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B. 2012 Chin Med pmid:22409910
Demirkan A et al. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 2012 PLoS Genet. pmid:22359512
Montefusco DJ et al. Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability. 2012 J. Biol. Chem. pmid:22277656
Young SA et al. Sphingolipid and ceramide homeostasis: potential therapeutic targets. 2012 Biochem Res Int pmid:22400113
Li SF et al. Isolation and functional characterisation of the genes encoding Δ(8)-sphingolipid desaturase from Brassica rapa. 2012 J Genet Genomics pmid:22293117
Chang Y et al. Metabolic profiling based on LC/MS to evaluate unintended effects of transgenic rice with cry1Ac and sck genes. 2012 Plant Mol. Biol. pmid:22271304
Huang X et al. Down-regulating sphingolipid synthesis increases yeast lifespan. 2012 PLoS Genet. pmid:22319457
Tiger CF et al. A framework for mapping, visualisation and automatic model creation of signal-transduction networks. 2012 Mol. Syst. Biol. pmid:22531118
Klose C et al. Flexibility of a eukaryotic lipidome--insights from yeast lipidomics. 2012 PLoS ONE pmid:22529973
Guo L et al. Connections between sphingosine kinase and phospholipase D in the abscisic acid signaling pathway in Arabidopsis. 2012 J. Biol. Chem. pmid:22275366
Schuster A et al. A versatile toolkit for high throughput functional genomics with Trichoderma reesei. 2012 Biotechnol Biofuels pmid:22212435
Dangerfield EM et al. Species-specific activity of glycolipid ligands for invariant NKT cells. 2012 Chembiochem pmid:22639457
Vandenbosch D et al. Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells. 2012 Antimicrob. Agents Chemother. pmid:22354293
Barreto-Bergter E et al. Structural analysis of fungal cerebrosides. 2011 Front Microbiol pmid:22164155
Chao DY et al. Sphingolipids in the root play an important role in regulating the leaf ionome in Arabidopsis thaliana. 2011 Plant Cell pmid:21421810
Veerapen N et al. Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation. 2011 Bioorg. Med. Chem. pmid:21145749
Nimrichter L and Rodrigues ML Fungal glucosylceramides: from structural components to biologically active targets of new antimicrobials. 2011 Front Microbiol pmid:22025918
Martinková M et al. A facile synthesis of D-ribo-C(20)-phytosphingosine and its C2 epimer from D-ribose. 2011 Carbohydr. Res. pmid:21703597
Fu C et al. Metabonomics study of the protective effects of green tea polyphenols on aging rats induced by d-galactose. 2011 J Pharm Biomed Anal pmid:21444175
Guillas I et al. A matter of fat: interaction between nitric oxide and sphingolipid signaling in plant cold response. 2011 Plant Signal Behav pmid:21248493
Hinder A et al. Investigation of the molecular structure of the human stratum corneum ceramides [NP] and [EOS] by mass spectrometry. 2011 Skin Pharmacol Physiol pmid:21212722
Zitomer NC and Riley RT Extraction and analysis of fumonisins and compounds indicative of fumonisin exposure in plant and mammalian tissues and cultured cells. 2011 Methods Mol. Biol. pmid:21567327
Brodesser S and Kolter T Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. 2011 J Lipids pmid:21490810
Van Zeebroeck G et al. A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. 2011 PLoS ONE pmid:21912684
Uchida Y The role of fatty acid elongation in epidermal structure and function. 2011 Dermatoendocrinol pmid:21695014
Ideta R et al. Orally administered glucosylceramide improves the skin barrier function by upregulating genes associated with the tight junction and cornified envelope formation. 2011 Biosci. Biotechnol. Biochem. pmid:21821935
Lee WS Integral hair lipid in human hair follicle. 2011 J. Dermatol. Sci. pmid:21906914
Momin AA et al. A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. 2011 J. Lipid Res. pmid:21415121
BÅ‚achnio-Zabielska A et al. Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity. 2011 Lipids pmid:21181285
Wun KS et al. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. 2011 Immunity pmid:21376639
Coddens A et al. Erythrocyte and porcine intestinal glycosphingolipids recognized by F4 fimbriae of enterotoxigenic Escherichia coli. 2011 PLoS ONE pmid:21949679
Merrill AH Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. 2011 Chem. Rev. pmid:21942574
Koeller CM and Heise N The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease. 2011 Enzyme Res pmid:21603271
Murakami I et al. Phytoceramide and sphingoid bases derived from brewer's yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors. 2011 Lipids Health Dis pmid:21861924
Cheng JM et al. An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells. 2011 Carbohydr. Res. pmid:21463856
Hasegawa T et al. Dietary glucosylceramide enhances cornified envelope formation via transglutaminase expression and involucrin production. 2011 Lipids pmid:21416143
Becker S et al. Follicular fluid high-density lipoprotein-associated sphingosine 1-phosphate (S1P) promotes human granulosa lutein cell migration via S1P receptor type 3 and small G-protein RAC1. 2011 Biol. Reprod. pmid:20980685
Loewith R and Hall MN Target of rapamycin (TOR) in nutrient signaling and growth control. 2011 Genetics pmid:22174183
Jung JC et al. Phytoceramide shows neuroprotection and ameliorates scopolamine-induced memory impairment. 2011 Molecules pmid:22037667
Liu Z et al. Total synthesis of α-1C-galactosylceramide, an immunostimulatory C-glycosphingolipid, and confirmation of the stereochemistry in the first-generation synthesis. 2011 J. Org. Chem. pmid:21958232
Bozna BL et al. Binding strength and dynamics of invariant natural killer cell T cell receptor/CD1d-glycosphingolipid interaction on living cells by single molecule force spectroscopy. 2011 J. Biol. Chem. pmid:21454514
Guo L et al. Phosphatidic acid binds and stimulates Arabidopsis sphingosine kinases. 2011 J. Biol. Chem. pmid:21330371
Bowe WP and Logan AC Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future? 2011 Gut Pathog pmid:21281494
Lee YJ et al. Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. 2011 PLoS ONE pmid:21264320
Jervis PJ et al. Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: rapid access to biologically active glycolipids. 2011 J. Org. Chem. pmid:21155575