phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phytosphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phytosphingosine?

phytosphingosine is suspected in Infection, Nodule, Dehydration, Neuropathy, nervous system disorder, Atopic and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with phytosphingosine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phytosphingosine?

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What functions are associated with phytosphingosine?


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What lipids are associated with phytosphingosine?

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What genes are associated with phytosphingosine?

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What common seen animal models are associated with phytosphingosine?

Knock-out

Knock-out are used in the study 'Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.' (Jenkins GM and Hannun YA, 2001) and Knock-out are used in the study 'SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.' (Brace JL et al., 2007).

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NCBI Entrez Crosslinks

All references with phytosphingosine

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Authors Title Published Journal PubMed Link
Carneiro P et al. Characterization of apoptosis-related oxidoreductases from Neurospora crassa. 2012 PLoS ONE pmid:22470547
Berkey R et al. Sphingolipids and plant defense/disease: the "death" connection and beyond. 2012 Front Plant Sci pmid:22639658
Healey KR et al. CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction. 2012 Mol. Microbiol. pmid:22909030
Wang L et al. Proteomic analysis of Rta2p-dependent raft-association of detergent-resistant membranes in Candida albicans. 2012 PLoS ONE pmid:22662216
Guo L and Wang X Crosstalk between Phospholipase D and Sphingosine Kinase in Plant Stress Signaling. 2012 Front Plant Sci pmid:22639650
Kołaczkowska A et al. The regulatory inputs controlling pleiotropic drug resistance and hypoxic response in yeast converge at the promoter of the aminocholesterol resistance gene RTA1. 2012 FEMS Yeast Res. pmid:22129104
Saigusa D et al. Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry. 2012 Anal Bioanal Chem pmid:22538778
Frank S et al. Structural characterization of Schistosoma mansoni adult worm glycosphingolipids reveals pronounced differences with those of cercariae. 2012 Glycobiology pmid:22241826
Zhao YY et al. Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS. 2012 Clin. Chim. Acta pmid:22227165
Schorsch C et al. High-level production of tetraacetyl phytosphingosine (TAPS) by combined genetic engineering of sphingoid base biosynthesis and L-serine availability in the non-conventional yeast Pichia ciferrii. 2012 Metab. Eng. pmid:22178746
Li SF et al. Isolation and functional characterisation of the genes encoding Δ(8)-sphingolipid desaturase from Brassica rapa. 2012 J Genet Genomics pmid:22293117
Baspinar Y and Borchert HH Penetration and release studies of positively and negatively charged nanoemulsions--is there a benefit of the positive charge? 2012 Int J Pharm pmid:22486953
Chang Y et al. Metabolic profiling based on LC/MS to evaluate unintended effects of transgenic rice with cry1Ac and sck genes. 2012 Plant Mol. Biol. pmid:22271304
Ramu Sridhar P et al. Stereoselective synthesis of C18-guggultetrol and C18-phytosphingosine analogues from D-fructose. 2012 Carbohydr. Res. pmid:22975277
Byun HJ et al. Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo. 2012 J. Dermatol. Sci. pmid:22209282
Tiger CF et al. A framework for mapping, visualisation and automatic model creation of signal-transduction networks. 2012 Mol. Syst. Biol. pmid:22531118
Klose C et al. Flexibility of a eukaryotic lipidome--insights from yeast lipidomics. 2012 PLoS ONE pmid:22529973
Guo L et al. Connections between sphingosine kinase and phospholipase D in the abscisic acid signaling pathway in Arabidopsis. 2012 J. Biol. Chem. pmid:22275366
Schuster A et al. A versatile toolkit for high throughput functional genomics with Trichoderma reesei. 2012 Biotechnol Biofuels pmid:22212435
Dangerfield EM et al. Species-specific activity of glycolipid ligands for invariant NKT cells. 2012 Chembiochem pmid:22639457