| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Kim S et al. | Efficient and selective synthesis of D-arabino-, D-lyxo-, and D-xylo-phytosphingosine from D-ribo-phytosphingosine. | 2008 | J. Org. Chem. | pmid:18197680 |
| Park JJ et al. | Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library. | 2008 | Bioorg. Chem. | pmid:18279909 |
| Kyogashima M et al. | Chemical and apoptotic properties of hydroxy-ceramides containing long-chain bases with unusual alkyl chain lengths. | 2008 | J. Biochem. | pmid:18420598 |
| Hannay K et al. | Buffering by gene duplicates: an analysis of molecular correlates and evolutionary conservation. | 2008 | BMC Genomics | pmid:19087332 |
| Castro A et al. | Increased resistance of complex I mutants to phytosphingosine-induced programmed cell death. | 2008 | J. Biol. Chem. | pmid:18474589 |
| Garcia J et al. | Mathematical modeling of pathogenicity of Cryptococcus neoformans. | 2008 | Mol. Syst. Biol. | pmid:18414484 |
| Dere RT and Zhu X | The first synthesis of a thioglycoside analogue of the immunostimulant KRN7000. | 2008 | Org. Lett. | pmid:18808135 |
| Leung L et al. | Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000. | 2008 | Org. Lett. | pmid:18798635 |
| Itonori S et al. | Structural characterization of glycosylinositolphospholipids with a blood group type B sugar unit from the edible mushroom, Hypsizygus marmoreus. | 2008 | Glycobiology | pmid:18450973 |
| Shang P et al. | Chemical modification of iGb3 increases IFN-gamma production by hepatic NKT cells. | 2008 | Int. Immunopharmacol. | pmid:18387506 |
| Worrall D et al. | Involvement of sphingosine kinase in plant cell signalling. | 2008 | Plant J. | pmid:18557834 |
| Pruett ST et al. | Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols. | 2008 | J. Lipid Res. | pmid:18499644 |
| Thevissen K et al. | Fungicidal activity of truncated analogues of dihydrosphingosine. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18524581 |
| Mormeneo D et al. | Fungal growth inhibitory properties of new phytosphingolipid analogues. | 2008 | J. Appl. Microbiol. | pmid:18005346 |
| Li Q et al. | Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries. | 2007 Nov-Dec | J Comb Chem | pmid:17896821 |
| Gutierrez AL et al. | Characterization of glycoinositolphosphoryl ceramide structure mutant strains of Cryptococcus neoformans. | 2007 | Glycobiology | pmid:17369287 |
| Vessey DA et al. | Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart. | 2007 | J. Biochem. Mol. Toxicol. | pmid:17912702 |
| Moon BS et al. | Synthesis of novel phytosphingosine derivatives and their preliminary biological evaluation for enhancing radiation therapy. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17920885 |
| Lee T et al. | Synthesis of pachastrissamine from phytosphingosine: a comparison of cyclic sulfate vs an epoxide intermediate in cyclization. | 2007 | Org. Lett. | pmid:17249779 |
| Kwon YB et al. | Anti-angiogenic effect of tetraacetyl-phytosphingosine. | 2007 | Exp. Dermatol. | pmid:17359337 |
| Yoon HJ et al. | Dihydroxylation of 2-vinylaziridine: efficient synthesis of D-ribo-phytosphingosine. | 2007 | Chem. Commun. (Camb.) | pmid:17279267 |
| Ryan PR et al. | A higher plant delta8 sphingolipid desaturase with a preference for (Z)-isomer formation confers aluminum tolerance to yeast and plants. | 2007 | Plant Physiol. | pmid:17600137 |
| Toba T et al. | Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17419054 |
| Li S et al. | basA regulates cell wall organization and asexual/sexual sporulation ratio in Aspergillus nidulans. | 2007 | Genetics | pmid:17409079 |
| Choi SY et al. | Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5. | 2007 | Oncol. Rep. | pmid:17143496 |
| Park MT et al. | Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. | 2007 | Mol. Cancer Ther. | pmid:17237268 |
| Walther TC et al. | Pkh-kinases control eisosome assembly and organization. | 2007 | EMBO J. | pmid:18034155 |
| Farwick M et al. | Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin. | 2007 | Int J Cosmet Sci | pmid:18489360 |
| Pavicic T et al. | Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris. | 2007 | Int J Cosmet Sci | pmid:18489348 |
| Mormeneo D et al. | Synthesis and preliminary antifungal evaluation of a library of phytosphingolipid analogues. | 2007 | Org. Biomol. Chem. | pmid:18004456 |
| Matto P et al. | A general and stereoselective route to alpha- or beta-galactosphingolipids via a common four-carbon building block. | 2007 | J. Org. Chem. | pmid:17784770 |
| Imamura T et al. | A rice dihydrosphingosine C4 hydroxylase (DSH1) gene, which is abundantly expressed in the stigmas, vascular cells and apical meristem, may be involved in fertility. | 2007 | Plant Cell Physiol. | pmid:17609219 |
| Corbe E et al. | Role of ceramide structure and its microenvironment on the conformational order of model stratum corneum lipids mixtures: an approach by FTIR spectroscopy. | 2007 | Chem. Phys. Lipids | pmid:17296172 |
| Cowart LA and Hannun YA | Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis. | 2007 | J. Biol. Chem. | pmid:17322298 |
| Shi L et al. | Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. | 2007 | Cell Res. | pmid:18059378 |
| Brace JL et al. | SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae. | 2007 | Genetics | pmid:17057230 |
| Alvarez-Vasquez F et al. | Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift. | 2007 | Theor Biol Med Model | pmid:17974024 |
| GusiÄ AG et al. | [New ceramides from sea sponge Oceanapia sp]. | 2006 May-Jun | Bioorg. Khim. | pmid:16808175 |
| Kim S et al. | Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin. | 2006 Jan-Mar | Mol. Med. | pmid:16838068 |
| Chang YJ et al. | Structure-activity relationships of dimethylsphingosine (DMS) derivatives and their effects on intracellular pH and Ca2+ in the U937 monocyte cell line. | 2006 | Arch. Pharm. Res. | pmid:16964761 |
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| van den Berg RJ et al. | An efficient synthesis of the natural tetrahydrofuran pachastrissamine starting from D-ribo-phytosphingosine. | 2006 | J. Org. Chem. | pmid:16409007 |
| Yilmaz E and Borchert HH | Effect of lipid-containing, positively charged nanoemulsions on skin hydration, elasticity and erythema--an in vivo study. | 2006 | Int J Pharm | pmid:16289984 |
| Kyogashima M et al. | Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF MS. | 2006 | Glycobiology | pmid:16670104 |
| Kim S et al. | Efficient synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine via a cyclic sulfate intermediate. | 2006 | J. Org. Chem. | pmid:17064054 |
| Garidel P | Structural organisation and phase behaviour of a stratum corneum lipid analogue: ceramide 3A. | 2006 | Phys Chem Chem Phys | pmid:16688309 |
| Cai Y et al. | A general, efficient and stereospecific route to sphingosine, sphinganines, phytosphingosines and their analogs. | 2006 | Org. Biomol. Chem. | pmid:16525559 |
phytosphingosine
phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phytosphingosine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phytosphingosine?
phytosphingosine is suspected in Infection, Nodule, Dehydration, Neuropathy, nervous system disorder, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with phytosphingosine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phytosphingosine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phytosphingosine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phytosphingosine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phytosphingosine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phytosphingosine?
Knock-out
Knock-out are used in the study 'Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.' (Jenkins GM and Hannun YA, 2001) and Knock-out are used in the study 'SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae.' (Brace JL et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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