Japtok L et al. |
Sphingosine 1-phosphate counteracts insulin signaling in pancreatic β-cells via the sphingosine 1-phosphate receptor subtype 2. |
2015 |
FASEB J. |
pmid:25911610
|
Stone ML et al. |
Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:25910934
|
Urtz N et al. |
Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. |
2015 |
Circ. Res. |
pmid:26129975
|
Desai P et al. |
Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. |
2015 |
Mol. Cell. Biochem. |
pmid:26350564
|
Moolenaar WH |
Introduction to the ECR special issue on lysophospholipids in biology. |
2015 |
Exp. Cell Res. |
pmid:25746723
|
Brulhart-Meynet MC et al. |
Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. |
2015 |
PLoS ONE |
pmid:25781943
|
Nojima H et al. |
Sphingolipids in liver injury, repair and regeneration. |
2015 |
Biol. Chem. |
pmid:25781682
|
Newton J et al. |
Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy. |
2015 |
Exp. Cell Res. |
pmid:25770011
|
Muñoz-Sáez E et al. |
Neuroprotective role of sphingosine-1-phosphate in L-BMAA treated neuroblastoma cells (SH-SY5Y). |
2015 |
Neurosci. Lett. |
pmid:25769802
|
Kang H et al. |
The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. |
2015 |
Stem Cells Dev. |
pmid:25761906
|
Carrera I et al. |
A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. |
2015 |
Biomed Res Int |
pmid:25759822
|
Ueda N |
Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. |
2015 |
Int J Mol Sci |
pmid:25751724
|
Zhao S and Li J |
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
2015 |
PLoS ONE |
pmid:25748447
|
O'Sullivan C and Dev KK |
Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. |
2015 |
J. Cell. Sci. |
pmid:26359302
|
Borup A et al. |
Apolipoprotein M in lipid metabolism and cardiometabolic diseases. |
2015 |
Curr. Opin. Lipidol. |
pmid:25551802
|
Montecucco F et al. |
Impact of systemic inflammation and autoimmune diseases on apoA-I and HDL plasma levels and functions. |
2015 |
Handb Exp Pharmacol |
pmid:25522998
|
Nofer JR |
Signal transduction by HDL: agonists, receptors, and signaling cascades. |
2015 |
Handb Exp Pharmacol |
pmid:25522990
|
Baranowski M et al. |
Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time- and intensity-dependent manner. |
2015 |
Eur. J. Appl. Physiol. |
pmid:25519954
|
Oskeritzian CA et al. |
The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses. |
2015 |
J. Allergy Clin. Immunol. |
pmid:25512083
|
Kurano M et al. |
LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. |
2015 |
J. Biol. Chem. |
pmid:25505264
|
Konstantinou D et al. |
Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. |
2015 |
Cell Biol. Int. |
pmid:25492631
|
Pyne NJ and Kolesnick RN |
The life and work of Dr. Robert Bittman (1942-2014). |
2015 |
Biol. Chem. |
pmid:25473803
|
Benesch MG et al. |
Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate. |
2015 |
J. Lipid Res. |
pmid:25896349
|
Klocke S et al. |
Slow-freezing versus vitrification for human ovarian tissue cryopreservation. |
2015 |
Arch. Gynecol. Obstet. |
pmid:25115279
|
Wysoczynski M et al. |
Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells. |
2015 |
Stem Cell Rev |
pmid:25086571
|
Burow P et al. |
Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. |
2015 |
Pflugers Arch. |
pmid:24965069
|
Pan HY et al. |
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis. |
2015 |
Int Endod J |
pmid:24931601
|
Siow D et al. |
Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. |
2015 |
Adv Biol Regul |
pmid:25319495
|
Sano N et al. |
New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury. |
2015 |
World J. Gastroenterol. |
pmid:26668502
|
Liu R et al. |
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. |
2015 |
J. Biol. Chem. |
pmid:26518876
|
Yu H et al. |
Effect of sphingosine-1-phosphate and myoblast transplantation on rat acute myocardial infarction. |
2015 |
Genet. Mol. Res. |
pmid:26535699
|
Wang R et al. |
Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. |
2015 |
J. Biol. Chem. |
pmid:26534962
|
Fujii S |
[Atherosclerosis, Chronic Inflammation, and Thrombosis: In Search of the Missing Link in Laboratory Medicine]. |
2015 |
Rinsho Byori |
pmid:26524900
|
Jones EE et al. |
Tissue biomarkers of drug efficacy: case studies using a MALDI-MSI workflow. |
2015 |
Bioanalysis |
pmid:26505686
|
Ramos-Perez WD et al. |
A map of the distribution of sphingosine 1-phosphate in the spleen. |
2015 |
Nat. Immunol. |
pmid:26502404
|
Winkler MS et al. |
Decreased serum concentrations of sphingosine-1-phosphate in sepsis. |
2015 |
Crit Care |
pmid:26498205
|
Matula K et al. |
Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer. |
2015 |
BMC Cancer |
pmid:26493335
|
Barnawi J et al. |
Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). |
2015 |
PLoS ONE |
pmid:26485657
|
Moruno Manchon JF et al. |
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. |
2015 |
Sci Rep |
pmid:26477494
|
Deng Z et al. |
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. |
2015 |
Nat Commun |
pmid:25907800
|
Wang K et al. |
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. |
2015 |
PLoS Genet. |
pmid:26474409
|
Kihara Y et al. |
Lysophospholipid receptors in drug discovery. |
2015 |
Exp. Cell Res. |
pmid:25499971
|
Kim ES et al. |
A natural piper-amide-like compound NED-135 exhibits a potent inhibitory effect on the invasive breast cancer cells. |
2015 |
Chem. Biol. Interact. |
pmid:25980589
|
Boczkowska-Radziwon B et al. |
Ozonation of human blood increases sphingosine-1-phosphate in plasma. |
2015 |
J. Physiol. Pharmacol. |
pmid:25903957
|
Cheng Y et al. |
Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP. |
2015 |
FASEB J. |
pmid:25690654
|
Choi S et al. |
A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:26361873
|
Flávia Nardy A et al. |
Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease. |
2015 |
Biomed Res Int |
pmid:26347020
|
Dai L et al. |
Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression. |
2015 |
Oncotarget |
pmid:26327294
|
Simón MV et al. |
Sphingosine-1-Phosphate Is a Crucial Signal for Migration of Retina Müller Glial Cells. |
2015 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26325420
|
Yang L et al. |
Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice. |
2015 |
Sci Rep |
pmid:26324256
|
Brünnert D et al. |
Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells. |
2015 |
Placenta |
pmid:26321412
|
Zhao YD et al. |
A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. |
2015 |
PLoS ONE |
pmid:26317340
|
Hsu CK et al. |
Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. |
2015 |
Br. J. Pharmacol. |
pmid:26359950
|
Michels M et al. |
Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage. |
2015 |
J. Infect. |
pmid:26183296
|
Checa A et al. |
Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. |
2015 |
Sci Rep |
pmid:26174087
|
Schaffert SA et al. |
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function. |
2015 |
J. Immunol. |
pmid:26163591
|
Gao Y et al. |
Sphingosine kinase 1 as an anticancer therapeutic target. |
2015 |
Drug Des Devel Ther |
pmid:26150697
|
Denimal D et al. |
Significant abnormalities of the HDL phosphosphingolipidome in type 1 diabetes despite normal HDL cholesterol concentration. |
2015 |
Atherosclerosis |
pmid:26142685
|
Yagi K et al. |
Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage. |
2015 |
Stroke |
pmid:26138121
|
Nakagawa Y and Chiba K |
Diversity and plasticity of microglial cells in psychiatric and neurological disorders. |
2015 |
Pharmacol. Ther. |
pmid:26129625
|
Jeong SK et al. |
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. |
2015 |
J. Dermatol. Sci. |
pmid:26113114
|
Marycz K et al. |
The effect of the bioactive sphingolipids S1P and C1P on multipotent stromal cells--new opportunities in regenerative medicine. |
2015 |
Cell. Mol. Biol. Lett. |
pmid:26110483
|
Hyder CL et al. |
Sphingolipids inhibit vimentin-dependent cell migration. |
2015 |
J. Cell. Sci. |
pmid:25908861
|
Tian H and Yu Z |
Resveratrol induces apoptosis of leukemia cell line K562 by modulation of sphingosine kinase-1 pathway. |
2015 |
Int J Clin Exp Pathol |
pmid:26045781
|
Rosenberg AJ et al. |
A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. |
2015 |
Appl Radiat Isot |
pmid:25931137
|
Trayssac M et al. |
Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody. |
2015 |
Am. J. Transplant. |
pmid:25930666
|
Pulkoski-Gross MJ et al. |
Sphingosine-1-phosphate metabolism: A structural perspective. |
2015 |
Crit. Rev. Biochem. Mol. Biol. |
pmid:25923252
|
Ader I et al. |
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer. |
2015 |
Oncotarget |
pmid:25915662
|
Al Alam N and Kreydiyyeh SI |
FTY720P inhibits hepatic Na(+)-K(+) ATPase via S1PR2 and PGE2. |
2016 |
Biochem. Cell Biol. |
pmid:27501354
|
Fu P et al. |
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. |
2016 |
J. Biol. Chem. |
pmid:27864331
|
Terashita T et al. |
Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. |
2016 |
Respir. Res. |
pmid:27829417
|
Hashimoto Y et al. |
Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. |
2016 |
Cell Biol. Int. |
pmid:27486054
|
Viswanathan P et al. |
Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27473658
|
Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
pmid:27467777
|
Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
pmid:27459945
|
Rumzhum NN et al. |
Effect of Sphingosine 1-Phosphate on Cyclo-Oxygenase-2 Expression, Prostaglandin E2 Secretion, and β2-Adrenergic Receptor Desensitization. |
2016 |
Am. J. Respir. Cell Mol. Biol. |
pmid:26098693
|
Zhang XE et al. |
Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. |
2016 |
PLoS ONE |
pmid:27187066
|
Ohtoyo M et al. |
Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate. |
2016 |
Cell Chem Biol |
pmid:27185637
|
Barnawi J et al. |
Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. |
2016 |
COPD |
pmid:27144721
|
Jin L et al. |
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined. |
2016 |
World J Surg Oncol |
pmid:27129720
|
Sanchez T |
Sphingosine-1-Phosphate Signaling in Endothelial Disorders. |
2016 |
Curr Atheroscler Rep |
pmid:27115142
|
Crespo I et al. |
Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. |
2016 |
J. Pineal Res. |
pmid:27101794
|
Tang X et al. |
Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate. |
2016 |
J. Lipid Res. |
pmid:26884614
|
Uranbileg B et al. |
Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. |
2016 |
PLoS ONE |
pmid:26886371
|
Chumanevich A et al. |
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. |
2016 |
Mediators Inflamm. |
pmid:26884643
|
Ko P et al. |
Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. |
2016 |
Sci Rep |
pmid:26877098
|
Luo B et al. |
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
2016 |
Immunity |
pmid:26872696
|
Petrache I and Berdyshev EV |
Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. |
2016 |
Annu. Rev. Physiol. |
pmid:26667073
|
Delgado A and MartÃnez-Cartro M |
Therapeutic Potential of the Modulation of Sphingosine-1-Phosphate Receptors. |
2016 |
Curr. Med. Chem. |
pmid:26639095
|
Yamamoto S et al. |
A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). |
2016 |
Mol. Biol. Cell |
pmid:26631556
|
Kakazu E et al. |
Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. |
2016 |
J. Lipid Res. |
pmid:26621917
|
Chen J et al. |
Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. |
2016 |
Biochim. Biophys. Acta |
pmid:26615875
|
Gao D et al. |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26859520
|
Scotti L et al. |
Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome. |
2016 |
Mol. Hum. Reprod. |
pmid:27645281
|
Neubauer HA et al. |
An oncogenic role for sphingosine kinase 2. |
2016 |
Oncotarget |
pmid:27588496
|
Zeng Y et al. |
Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. |
2016 |
Oncotarget |
pmid:27556509
|
Nigro E et al. |
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation. |
2016 |
Pharmacol. Res. |
pmid:26462929
|
Serdar M et al. |
Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. |
2016 |
Brain Behav. Immun. |
pmid:26456693
|
Arish M et al. |
Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. |
2016 |
Drug Discov. Today |
pmid:26456576
|
Melnik BC |
Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research. |
2016 |
Acta Derm. Venereol. |
pmid:26304030
|