Kleuser B et al. |
1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. |
1998 |
Cancer Res. |
pmid:9581819
|
Qiao L et al. |
Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9871527
|
Sato K et al. |
Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9878524
|
Hida H et al. |
Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes. |
1998 |
J. Neurosci. |
pmid:9786978
|
Vasta V et al. |
Effects of sphingosine 1-phosphate and bradykinin on phospholipid signalling in human epithelial A549 cells. |
1998 |
Biochem. Soc. Trans. |
pmid:9765948
|
Edsall LC et al. |
N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide. |
1998 |
Biochemistry |
pmid:9737868
|
Orlati S et al. |
Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. |
1998 |
Cell Calcium |
pmid:9924630
|
Goetzl EJ and An S |
Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. |
1998 |
FASEB J. |
pmid:9837849
|
Lanterman MM and Saba JD |
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. |
1998 |
Biochem. J. |
pmid:9601083
|
Cuvillier O et al. |
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. |
1998 |
J. Biol. Chem. |
pmid:9446602
|
Okamoto H et al. |
EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. |
1998 |
J. Biol. Chem. |
pmid:9765227
|
Takeda H et al. |
Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. |
1998 |
FEBS Lett. |
pmid:9490019
|
Van Brocklyn JR et al. |
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. |
1998 |
J. Cell Biol. |
pmid:9660876
|
Mandala SM et al. |
Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9419344
|
Guo C et al. |
Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. |
1998 |
Eur. J. Biochem. |
pmid:9826186
|
Xia P et al. |
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9826677
|
Meyer zu Heringdorf D et al. |
Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors. |
1998 |
EMBO J. |
pmid:9582276
|
Noh SJ et al. |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes. |
1998 |
J. Cell. Physiol. |
pmid:9648929
|
Lee MJ et al. |
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. |
1998 |
Science |
pmid:9488656
|
Melendez A et al. |
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. |
1998 |
J. Biol. Chem. |
pmid:9545263
|
Gueguen G et al. |
Structure-activity analysis of the effects of lysophosphatidic acid on platelet aggregation. |
1999 |
Biochemistry |
pmid:10387090
|
Rakhit S et al. |
Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. |
1999 |
Biochem. J. |
pmid:10051434
|
Spiegel S |
Sphingosine 1-phosphate: a prototype of a new class of second messengers. |
1999 |
J. Leukoc. Biol. |
pmid:10080537
|
Liu CH et al. |
Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1. |
1999 |
Mol. Biol. Cell |
pmid:10198065
|
Watanabe Y and Akaike T |
Possible involvement of caspase-like family in maintenance of cytoskeleton integrity. |
1999 |
J. Cell. Physiol. |
pmid:10082131
|
Shinpo K et al. |
Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons. |
1999 |
Brain Res. |
pmid:10082875
|
Wang F et al. |
Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate. |
1999 |
Exp. Cell Res. |
pmid:10047444
|
Goetzl EJ et al. |
Dual mechanisms for lysophospholipid induction of proliferation of human breast carcinoma cells. |
1999 |
Cancer Res. |
pmid:10493533
|
Goetzl EJ et al. |
Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. |
1999 |
Cancer Res. |
pmid:10537322
|
Lee OH et al. |
Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10544002
|
Olivera A et al. |
Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. |
1999 |
J. Cell Biol. |
pmid:10545499
|
Hung WC et al. |
Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. |
1999 |
Biochem. J. |
pmid:9931312
|
Moore AN et al. |
Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes. |
1999 |
Neuroscience |
pmid:10579204
|
Zhang G et al. |
Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. |
1999 |
Gene |
pmid:9931453
|
Moolenaar WH |
Bioactive lysophospholipids and their G protein-coupled receptors. |
1999 |
Exp. Cell Res. |
pmid:10579925
|
Yang L et al. |
Metabolism and functional effects of sphingolipids in blood cells. |
1999 |
Br. J. Haematol. |
pmid:10583213
|
Sato K et al. |
Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. |
1999 |
Mol. Pharmacol. |
pmid:9882706
|
Lynch KR and Im DS |
Life on the edg. |
1999 |
Trends Pharmacol. Sci. |
pmid:10603487
|
Goetzl EJ et al. |
Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. |
1999 |
J. Immunol. |
pmid:9973477
|
Stewart CE et al. |
Increased tyrosine kinase activity but not calcium mobilization is required for ceramide-induced apoptosis. |
1999 |
Exp. Cell Res. |
pmid:10413587
|
Sabbadini RA et al. |
The role of sphingolipids in the control of skeletal muscle function: a review. |
1999 |
Ital J Neurol Sci |
pmid:10937863
|
Gottlieb D et al. |
The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae. |
1999 |
Mol. Cell Biol. Res. Commun. |
pmid:10329480
|
Goetzl EJ and An S |
A subfamily of G protein-coupled cellular receptors for lysophospholipids and lysosphingolipids. |
1999 |
Adv. Exp. Med. Biol. |
pmid:10667339
|
Carpio LC et al. |
Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells. |
1999 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10670688
|
Wang F et al. |
Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. |
1999 |
Cancer Res. |
pmid:10626811
|
Wang F et al. |
Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis. |
1999 |
J. Biol. Chem. |
pmid:10585401
|
Van Brocklyn JR et al. |
Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. |
1999 |
J. Biol. Chem. |
pmid:9988698
|
Yang L et al. |
Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors. |
1999 |
J. Biochem. |
pmid:10393324
|
Alemany R et al. |
Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. |
1999 |
J. Biol. Chem. |
pmid:9933590
|
Zhang Q et al. |
Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway. |
1999 |
Blood |
pmid:10216094
|