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Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. |
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Eur. J. Pharmacol. |
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Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. |
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Respir. Res. |
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Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. |
2016 |
Stroke |
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Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei. |
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Mol. Microbiol. |
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Targeting sphingosine-1-phosphate signaling in lung diseases. |
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Pharmacol. Ther. |
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Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis. |
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J. Surg. Res. |
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Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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Hernández-Coronado CG et al. |
Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. |
2016 |
Gen. Comp. Endocrinol. |
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Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease. |
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Curr Alzheimer Res |
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Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances. |
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Prog. Lipid Res. |
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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential. |
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Mediators Inflamm. |
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Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. |
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Arterioscler. Thromb. Vasc. Biol. |
pmid:26966278
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Chawla S et al. |
S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. |
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IUBMB Life |
pmid:26959531
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Chapurlat RD and Confavreux CB |
Novel biological markers of bone: from bone metabolism to bone physiology. |
2016 |
Rheumatology (Oxford) |
pmid:26790456
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Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. |
2016 |
PLoS ONE |
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S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. |
2016 |
J. Immunol. |
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Integrated sphingosine-1 phosphate signaling in the central nervous system: From physiological equilibrium to pathological damage. |
2016 |
Pharmacol. Res. |
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Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. |
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J. Biol. Chem. |
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Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling. |
2016 |
Mol. Cell. Biol. |
pmid:26552704
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Liu X et al. |
Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. |
2016 |
Exp. Biol. Med. (Maywood) |
pmid:26376826
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