Castillo-Badillo JA et al. |
α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization. |
2015 |
PLoS ONE |
pmid:25799564
|
Brulhart-Meynet MC et al. |
Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. |
2015 |
PLoS ONE |
pmid:25781943
|
Borup A et al. |
Apolipoprotein M in lipid metabolism and cardiometabolic diseases. |
2015 |
Curr. Opin. Lipidol. |
pmid:25551802
|
Montecucco F et al. |
Impact of systemic inflammation and autoimmune diseases on apoA-I and HDL plasma levels and functions. |
2015 |
Handb Exp Pharmacol |
pmid:25522998
|
Moon MH et al. |
Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate. |
2015 |
Mol Med Rep |
pmid:25351259
|
Liu R et al. |
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. |
2015 |
J. Biol. Chem. |
pmid:26518876
|
Wang R et al. |
Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. |
2015 |
J. Biol. Chem. |
pmid:26534962
|
Fujii S |
[Atherosclerosis, Chronic Inflammation, and Thrombosis: In Search of the Missing Link in Laboratory Medicine]. |
2015 |
Rinsho Byori |
pmid:26524900
|
Zeng Y et al. |
Sphingosine 1-phosphate induced synthesis of glycocalyx on endothelial cells. |
2015 |
Exp. Cell Res. |
pmid:26364737
|
Choi S et al. |
A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing. |
2015 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:26361873
|
Hsu CK et al. |
Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. |
2015 |
Br. J. Pharmacol. |
pmid:26359950
|
Michels M et al. |
Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage. |
2015 |
J. Infect. |
pmid:26183296
|
Checa A et al. |
Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. |
2015 |
Sci Rep |
pmid:26174087
|
Prager B et al. |
Sphingosine 1-phosphate signaling at the blood-brain barrier. |
2015 |
Trends Mol Med |
pmid:25939882
|
Rosenberg AJ et al. |
A practical process for the preparation of [(32)P]S1P and binding assay for S1P receptor ligands. |
2015 |
Appl Radiat Isot |
pmid:25931137
|
Trayssac M et al. |
Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody. |
2015 |
Am. J. Transplant. |
pmid:25930666
|
Rao PV |
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
2014 Mar-Apr |
J Ocul Pharmacol Ther |
pmid:24283588
|
Che W et al. |
Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. |
2014 |
Am. J. Respir. Cell Mol. Biol. |
pmid:24032470
|
Chang N et al. |
Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. |
2014 |
J. Cell. Biochem. |
pmid:24038457
|
Völzke A et al. |
Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. |
2014 |
Biochim. Biophys. Acta |
pmid:24064301
|
Pyne NJ et al. |
The role of sphingosine 1-phosphate in inflammation and cancer. |
2014 |
Adv Biol Regul |
pmid:24070975
|
Nguyen-Tran DH et al. |
Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. |
2014 |
Dis Model Mech |
pmid:24077965
|
Tanaka K et al. |
Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model. |
2014 |
Clin. Exp. Immunol. |
pmid:24028747
|
Kihara A |
Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids. |
2014 |
Biochim. Biophys. Acta |
pmid:23994042
|
Gorlino CV et al. |
Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes. |
2014 |
J. Immunol. |
pmid:25015824
|
Anderson G and Maes M |
Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions. |
2014 |
CNS Neurol Disord Drug Targets |
pmid:24040808
|
Waeber C and Walther T |
Sphingosine-1-phosphate as a potential target for the treatment of myocardial infarction. |
2014 |
Circ. J. |
pmid:24632793
|
Willinger T et al. |
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. |
2014 |
J. Exp. Med. |
pmid:24638168
|
Purschke WG et al. |
Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis. |
2014 |
Biochem. J. |
pmid:24832383
|
Karaca I et al. |
Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein. |
2014 |
J. Biol. Chem. |
pmid:24808180
|
Snider AJ et al. |
Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. |
2014 |
PLoS ONE |
pmid:25460165
|
Nakanaga K et al. |
Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. |
2014 |
J. Biochem. |
pmid:24451492
|
Langeslag M et al. |
Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons. |
2014 |
Mol Pain |
pmid:25431213
|
Kim YI et al. |
An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production. |
2014 |
Mol. Cell. Biol. |
pmid:25312644
|
Miller DS |
Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24385389
|
Dai L et al. |
Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? |
2014 |
Cancer Invest. |
pmid:24499107
|
Ito K et al. |
Integrin α9 on lymphatic endothelial cells regulates lymphocyte egress. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:24516133
|
Takeshita E et al. |
Diacylglycerol kinase γ is a novel anionic phospholipid binding protein with a selective binding preference. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24486543
|
Kamiya T et al. |
Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro. |
2014 |
Exp. Eye Res. |
pmid:24486793
|
Plano D et al. |
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. |
2014 |
J. Med. Chem. |
pmid:24471412
|
Nakamura H and Murayama T |
Role of sphingolipids in arachidonic acid metabolism. |
2014 |
J. Pharmacol. Sci. |
pmid:24599139
|
Guo S et al. |
Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen. |
2014 |
Biochim. Biophys. Acta |
pmid:24603322
|
Keller J et al. |
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. |
2014 |
Nat Commun |
pmid:25333900
|
Kempf A et al. |
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. |
2014 |
PLoS Biol. |
pmid:24453941
|
Lepletier A et al. |
Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. |
2014 |
PLoS Negl Trop Dis |
pmid:25330249
|
Tao C et al. |
Regulation of glucose and lipid homeostasis by adiponectin: effects on hepatocytes, pancreatic β cells and adipocytes. |
2014 |
Best Pract. Res. Clin. Endocrinol. Metab. |
pmid:24417945
|
Bradley E et al. |
Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
2014 |
PLoS ONE |
pmid:25330231
|
Hamidi S et al. |
TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts. |
2014 |
Biochim. Biophys. Acta |
pmid:24440818
|
Xu H et al. |
Sphingosine-1-phosphate receptor agonist, FTY720, restores coronary flow reserve in diabetic rats. |
2014 |
Circ. J. |
pmid:25319164
|
Schaper K et al. |
Sphingosine-1-phosphate differently regulates the cytokine production of IL-12, IL-23 and IL-27 in activated murine bone marrow derived dendritic cells. |
2014 |
Mol. Immunol. |
pmid:24434636
|
Fukui H et al. |
S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish. |
2014 |
Dev. Cell |
pmid:25313964
|
Obinata H et al. |
Individual variation of human S1Pâ‚ coding sequence leads to heterogeneity in receptor function and drug interactions. |
2014 |
J. Lipid Res. |
pmid:25293589
|
Fernández-Pisonero I et al. |
Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells. |
2014 |
PLoS ONE |
pmid:25275309
|
Sassoli C et al. |
Mesenchymal stromal cell secreted sphingosine 1-phosphate (S1P) exerts a stimulatory effect on skeletal myoblast proliferation. |
2014 |
PLoS ONE |
pmid:25264785
|
Silva VR et al. |
Hypothalamic S1P/S1PR1 axis controls energy homeostasis. |
2014 |
Nat Commun |
pmid:25255053
|
Hirata N et al. |
Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation. |
2014 |
Nat Commun |
pmid:25254944
|
Iino J et al. |
Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells. |
2014 |
Lipids Health Dis |
pmid:25253303
|
Kim ES et al. |
Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. |
2014 |
Oncogene |
pmid:23955082
|
St John AL et al. |
S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. |
2014 |
Immunity |
pmid:25238098
|
Davis KM and Isberg RR |
Plague's partners in crime. |
2014 |
Immunity |
pmid:25238090
|
Bi Y et al. |
Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. |
2014 |
Am. J. Pathol. |
pmid:25111230
|
Ishitsuka A et al. |
FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
Int. J. Mol. Med. |
pmid:25109763
|
Xiong H et al. |
SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling. |
2014 |
Oncol. Rep. |
pmid:25109605
|
Rolin J and Maghazachi AA |
Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. |
2014 |
J. Leukoc. Biol. |
pmid:24493826
|
Zhao X et al. |
Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:25106095
|
Li MH et al. |
Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. |
2014 |
J. Pediatr. Surg. |
pmid:25092091
|
Awojoodu AO et al. |
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. |
2014 |
Blood |
pmid:25075126
|
Belvitch P et al. |
Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics. |
2014 |
Microvasc. Res. |
pmid:25072537
|
Mendes-da-Cruz DA et al. |
Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. |
2014 |
PLoS ONE |
pmid:25068647
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes. |
2014 |
Int. J. Mol. Med. |
pmid:25050633
|
Wakashima T et al. |
Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation. |
2014 |
J. Biol. Chem. |
pmid:25049234
|
Tsai YC et al. |
Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. |
2014 |
Reprod Sci |
pmid:23793475
|
Snelder N et al. |
Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation. |
2014 |
Drug Metab. Dispos. |
pmid:24965813
|
BÅ‚ogowski W et al. |
Perioperative release of pro-regenerative biochemical signals from human renal allografts subjected to ischemia-reperfusion injury. |
2014 |
Innate Immun |
pmid:23608824
|
Tarbell JM et al. |
Mechanosensing at the vascular interface. |
2014 |
Annu Rev Biomed Eng |
pmid:24905872
|
Potì F et al. |
Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). |
2014 |
Cardiovasc. Res. |
pmid:24891400
|
Chawla S et al. |
Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. |
2014 |
PLoS ONE |
pmid:24887065
|
Janes K et al. |
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. |
2014 |
J. Biol. Chem. |
pmid:24876379
|
Yan W et al. |
Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:24852843
|
Sheridan GK and Dev KK |
Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations. |
2014 |
Sci Rep |
pmid:24851861
|
Ni X et al. |
Interaction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancement. |
2014 |
J. Cell. Biochem. |
pmid:24851274
|
Vanoli E et al. |
Vagomimetic effects of fingolimod: physiology and clinical implications. |
2014 |
CNS Neurosci Ther |
pmid:24836740
|
Zhang GQ et al. |
Sphingosine-1-phosphate receptors respond differently to early myocardial ischemia and ischemia-reperfusion in vivo. |
2014 |
Sheng Li Xue Bao |
pmid:24777407
|
Ceglarek U et al. |
Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. |
2014 |
Clin. Chim. Acta |
pmid:24768784
|
Smyth SS et al. |
Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. |
2014 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:24482375
|
Takabe K and Spiegel S |
Export of sphingosine-1-phosphate and cancer progression. |
2014 |
J. Lipid Res. |
pmid:24474820
|
Ishizawa S et al. |
Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor. |
2014 |
Clin. Exp. Nephrol. |
pmid:24463961
|
Couttas TA et al. |
Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis. |
2014 |
Acta Neuropathol Commun |
pmid:24456642
|
Gassowska M et al. |
Sphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells. |
2014 |
Neurochem. Res. |
pmid:24452756
|
Borge M et al. |
The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. |
2014 |
J. Immunol. |
pmid:25127862
|
Fujii K et al. |
Sphingosine 1-phosphate increases an intracellular Ca(2+) concentration via S1P3 receptor in cultured vascular smooth muscle cells. |
2014 |
J. Pharm. Pharmacol. |
pmid:24450400
|
Ito S et al. |
TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. |
2014 |
Coron. Artery Dis. |
pmid:24448174
|
Czubowicz K and Strosznajder R |
Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate. |
2014 |
Mol. Neurobiol. |
pmid:24420784
|
Kerage D et al. |
Review: novel insights into the regulation of vascular tone by sphingosine 1-phosphate. |
2014 |
Placenta |
pmid:24411702
|
Gil-Ortega M et al. |
Ex vivo microperfusion system of the adipose organ: a new approach to studying the mobilization of adipose cell populations. |
2014 |
Int J Obes (Lond) |
pmid:24357852
|
Abu El-Asrar AM et al. |
Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy. |
2014 |
Lipids Health Dis |
pmid:25496321
|
Jensen T et al. |
The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. |
2014 |
Bioorg. Med. Chem. Lett. |
pmid:25442311
|
Ye C et al. |
Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24633425
|
Pyszko J and Strosznajder JB |
Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. |
2014 |
Mol. Neurobiol. |
pmid:24399507
|
Nishi T et al. |
Molecular and physiological functions of sphingosine 1-phosphate transporters. |
2014 |
Biochim. Biophys. Acta |
pmid:23921254
|