Cuvillier O |
Sphingosine in apoptosis signaling. |
2002 |
Biochim. Biophys. Acta |
pmid:12531549
|
Osada M et al. |
Modulation of sphingosine 1-phosphate/EDG signaling by tumor necrosis factor-alpha in vascular endothelial cells. |
2002 |
Thromb. Res. |
pmid:12590954
|
Tanski W et al. |
Sphingosine-1-phosphate induces G(alphai)-coupled, PI3K/ras-dependent smooth muscle cell migration. |
2002 |
J. Surg. Res. |
pmid:12443721
|
Osada M et al. |
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12445827
|
Grey A et al. |
The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving G(i) proteins and phosphatidylinositol-3 kinase. |
2002 |
Endocrinology |
pmid:12446603
|
Ghelli A et al. |
Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta. |
2002 |
Biochem. J. |
pmid:12014986
|
Auge N et al. |
Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways. |
2002 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12482824
|
Nava VE et al. |
Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells. |
2002 |
Exp. Cell Res. |
pmid:12441135
|
Benaud CM et al. |
Deregulated activation of matriptase in breast cancer cells. |
2002 |
Clin. Exp. Metastasis |
pmid:12498394
|
Maceyka M et al. |
Sphingosine kinase, sphingosine-1-phosphate, and apoptosis. |
2002 |
Biochim. Biophys. Acta |
pmid:12531554
|
Chin TY et al. |
Distinct effects of different calcium-mobilizing agents on cell death in NG108-15 neuroblastoma X glioma cells. |
2002 |
Mol. Pharmacol. |
pmid:11854428
|
Mandala S et al. |
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. |
2002 |
Science |
pmid:11923495
|
Ancellin N et al. |
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. |
2002 |
J. Biol. Chem. |
pmid:11741921
|
Benaud C et al. |
Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase. |
2002 |
J. Biol. Chem. |
pmid:11792696
|
Wang J et al. |
Receptor-mediated activation of a Cl(-) current by LPA and S1P in cultured corneal keratocytes. |
2002 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12356825
|
Van Brocklyn J et al. |
Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase beta. |
2002 |
Cancer Lett. |
pmid:12175535
|
Birbes H et al. |
Mitochondria and ceramide: intertwined roles in regulation of apoptosis. |
2002 |
Adv. Enzyme Regul. |
pmid:12123710
|
Johnson KR et al. |
PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA). |
2002 |
J. Biol. Chem. |
pmid:12124383
|
Thamilselvan V et al. |
Sphingosine-1-phosphate stimulates human Caco-2 intestinal epithelial proliferation via p38 activation and activates ERK by an independent mechanism. |
2002 |
In Vitro Cell. Dev. Biol. Anim. |
pmid:12197778
|
Coussin F et al. |
Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction. |
2002 |
Circ. Res. |
pmid:12142348
|
Wang L et al. |
Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells. |
2002 |
Biochem. J. |
pmid:12149127
|
Kveberg L et al. |
Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases. |
2002 |
Eur. J. Immunol. |
pmid:12115604
|
Spiegel S and Kolesnick R |
Sphingosine 1-phosphate as a therapeutic agent. |
2002 |
Leukemia |
pmid:12200669
|
Paris F et al. |
Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring. |
2002 |
Nat. Med. |
pmid:12205432
|
Davaille J et al. |
Sphingosine 1-phosphate triggers both apoptotic and survival signals for human hepatic myofibroblasts. |
2002 |
J. Biol. Chem. |
pmid:12138095
|
Kihara A and Igarashi Y |
[Sphingosine 1-phosphate in yeast]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915338
|
Okazaki T and Ito M |
[Signal transduction of ceramide]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915339
|
Igarashi Y |
[Current studies on a novel lipid mediator, sphingosine 1-phosphate, and its receptors]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915345
|
Okajima F |
[Distribution of sphingosine 1-phosphate in plasma lipoproteins and its role in the regulation of the vascular cell functions]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915346
|
Yatomi Y et al. |
[Sphingosine 1-phosphate and vascular endothelial cells]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915347
|
Takuwa Y |
[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915348
|
Tsukahara T et al. |
[Molecular diversity of sphingosine kinase]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915350
|
Rikitake Y et al. |
Involvement of endothelial nitric oxide in sphingosine-1-phosphate-induced angiogenesis. |
2002 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11788469
|
Graeler M et al. |
Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate. |
2002 |
J. Immunol. |
pmid:12370333
|
Takuwa Y et al. |
The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities. |
2002 |
J. Biochem. |
pmid:12038970
|
Meacci E et al. |
A role for calcium in sphingosine 1-phosphate-induced phospholipase D activity in C2C12 myoblasts. |
2002 |
FEBS Lett. |
pmid:12067705
|
Le Stunff H et al. |
Sphingosine-1-phosphate and lipid phosphohydrolases. |
2002 |
Biochim. Biophys. Acta |
pmid:12069805
|
Kluk MJ and Hla T |
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. |
2002 |
Biochim. Biophys. Acta |
pmid:12069812
|
Siehler S and Manning DR |
Pathways of transduction engaged by sphingosine 1-phosphate through G protein-coupled receptors. |
2002 |
Biochim. Biophys. Acta |
pmid:12069815
|
Takuwa Y |
Subtype-specific differential regulation of Rho family G proteins and cell migration by the Edg family sphingosine-1-phosphate receptors. |
2002 |
Biochim. Biophys. Acta |
pmid:12069818
|
Pyne S and Pyne NJ |
Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors. |
2002 |
Biochim. Biophys. Acta |
pmid:12069819
|
Okajima F |
Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator? |
2002 |
Biochim. Biophys. Acta |
pmid:12069820
|
Meyer zu Heringdorf D et al. |
Sphingosylphosphorylcholine-biological functions and mechanisms of action. |
2002 |
Biochim. Biophys. Acta |
pmid:12069827
|
Panetti TS |
Differential effects of sphingosine 1-phosphate and lysophosphatidic acid on endothelial cells. |
2002 |
Biochim. Biophys. Acta |
pmid:12069828
|
Siess W |
Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate. |
2002 |
Biochim. Biophys. Acta |
pmid:12069830
|
Karliner JS |
Lysophospholipids and the cardiovascular system. |
2002 |
Biochim. Biophys. Acta |
pmid:12069831
|
English D et al. |
Lipid mediators of angiogenesis and the signalling pathways they initiate. |
2002 |
Biochim. Biophys. Acta |
pmid:12069833
|
Spiegel S et al. |
Sphingosine 1-phosphate signaling: providing cells with a sense of direction. |
2002 |
Trends Cell Biol. |
pmid:12062172
|
Kohno T et al. |
N-glycans of sphingosine 1-phosphate receptor Edg-1 regulate ligand-induced receptor internalization. |
2002 |
FASEB J. |
pmid:12087059
|
Baudhuin LM et al. |
Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. |
2002 |
Mol. Pharmacol. |
pmid:12181443
|
Osawa Y et al. |
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. |
2001 |
J. Immunol. |
pmid:11418646
|
Boujaoude LC et al. |
Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. |
2001 |
J. Biol. Chem. |
pmid:11443135
|
Paik JH et al. |
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. |
2001 |
J. Biol. Chem. |
pmid:11150298
|
Meyer zu Heringdorf D et al. |
Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors. |
2001 |
Eur. J. Pharmacol. |
pmid:11239914
|
Young KW and Nahorski SR |
Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+ release. |
2001 |
Semin. Cell Dev. Biol. |
pmid:11162743
|
English D et al. |
Platelet-released phospholipids link haemostasis and angiogenesis. |
2001 |
Cardiovasc. Res. |
pmid:11166272
|
Radin NS |
Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come? |
2001 |
Eur. J. Biochem. |
pmid:11168352
|
Karliner JS et al. |
The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes. |
2001 |
J. Mol. Cell. Cardiol. |
pmid:11549349
|
Siehler S et al. |
Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells. |
2001 |
J. Biol. Chem. |
pmid:11673450
|
Cuvillier O and Levade T |
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria. |
2001 |
Blood |
pmid:11675357
|
Tigyi G |
Selective ligands for lysophosphatidic acid receptor subtypes: gaining control over the endothelial differentiation gene family. |
2001 |
Mol. Pharmacol. |
pmid:11723220
|
Castillo SS and Teegarden D |
Ceramide conversion to sphingosine-1-phosphate is essential for survival in C3H10T1/2 cells. |
2001 |
J. Nutr. |
pmid:11694603
|
Lyons JM and Karin NJ |
A role for G protein-coupled lysophospholipid receptors in sphingolipid-induced Ca2+ signaling in MC3T3-E1 osteoblastic cells. |
2001 |
J. Bone Miner. Res. |
pmid:11697799
|
Ohmori T et al. |
G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways. |
2001 |
J. Biol. Chem. |
pmid:11056155
|
Erl W and Siess W |
Sphingosine-1-phosphate and the leading Edg-1 of vascular smooth muscle cells. |
2001 |
Circ. Res. |
pmid:11557732
|
Malek RL et al. |
Nrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptors. |
2001 |
J. Biol. Chem. |
pmid:11069896
|
Kluk MJ and Hla T |
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. |
2001 |
Circ. Res. |
pmid:11557736
|
Meacci E et al. |
Dual regulation of sphingosine 1-phosphate-induced phospholipase D activity through RhoA and protein kinase C-alpha in C2C12 myoblasts. |
2001 |
Cell. Signal. |
pmid:11483412
|
Pébay A et al. |
Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades. |
2001 |
Eur. J. Neurosci. |
pmid:11467306
|
Brownlee C |
Intracellular signalling: sphingosine-1-phosphate branches out. |
2001 |
Curr. Biol. |
pmid:11470429
|
Igarashi J and Michel T |
Sphingosine 1-phosphate and isoform-specific activation of phosphoinositide 3-kinase beta. Evidence for divergence and convergence of receptor-regulated endothelial nitric-oxide synthase signaling pathways. |
2001 |
J. Biol. Chem. |
pmid:11470796
|
Garcia JG et al. |
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. |
2001 |
J. Clin. Invest. |
pmid:11544274
|
Nadal A et al. |
Glial cell responses to lipids bound to albumin in serum and plasma. |
2001 |
Prog. Brain Res. |
pmid:11545003
|
Sullards MC and Merrill AH |
Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. |
2001 |
Sci. STKE |
pmid:11752637
|
Hla T |
Sphingosine 1-phosphate receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324703
|
Mandala SM |
Sphingosine-1-phosphate phosphatases. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324704
|
Lynch KR and Macdonald TL |
Structure activity relationships of lysophospholipid mediators. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324706
|
Panetti TS et al. |
Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324710
|
Alderton F et al. |
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells. |
2001 |
J. Biol. Chem. |
pmid:11278307
|
Igarashi J et al. |
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278407
|
Morales-Ruiz M et al. |
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278592
|
Birchwood CJ et al. |
Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. |
2001 |
J. Biol. Chem. |
pmid:11278643
|
Ng CK et al. |
Drought-induced guard cell signal transduction involves sphingosine-1-phosphate. |
2001 |
Nature |
pmid:11279499
|
Kranenburg O and Moolenaar WH |
Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists. |
2001 |
Oncogene |
pmid:11313900
|
Schwartz BM et al. |
Lysophospholipids increase interleukin-8 expression in ovarian cancer cells. |
2001 |
Gynecol. Oncol. |
pmid:11330965
|
Hobson JP et al. |
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. |
2001 |
Science |
pmid:11230698
|
Alderton F et al. |
Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells. |
2001 |
J. Biol. Chem. |
pmid:11359779
|
Pébay A et al. |
Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts. |
2001 |
Eur. J. Neurosci. |
pmid:11422447
|
Kimura T et al. |
Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11427538
|
Ishii I et al. |
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. |
2001 |
J. Biol. Chem. |
pmid:11443127
|
Kralik SF et al. |
A method for quantitative extraction of sphingosine 1-phosphate into organic solvent. |
2001 |
Anal. Biochem. |
pmid:11444818
|
Wells CD et al. |
Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor. |
2001 |
J. Biol. Chem. |
pmid:11384980
|
Liu F et al. |
Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. |
2001 |
Am. J. Respir. Cell Mol. Biol. |
pmid:11415936
|
Osawa Y et al. |
Sphingosine kinase regulates hepatoma cell differentiation: roles of hepatocyte nuclear factor and retinoid receptor. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11520048
|
Repp H et al. |
Activation of a Ca2+-dependent K+ current in mouse fibroblasts by sphingosine-1-phosphate involves the protein tyrosine kinase c-Src. |
2001 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:11284444
|
Takuwa Y et al. |
Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11377814
|
Banno Y et al. |
Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3. |
2001 |
J. Biol. Chem. |
pmid:11468290
|
Tilly JL |
Emerging technologies to control oocyte apoptosis are finally treading on fertile ground. |
2001 |
ScientificWorldJournal |
pmid:12805661
|
Blaukat A and Dikic I |
Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. |
2001 |
Biol. Chem. |
pmid:11258664
|
Alemany R et al. |
Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate. |
2001 |
FEBS Lett. |
pmid:11741596
|