Birgbauer E and Chun J |
New developments in the biological functions of lysophospholipids. |
2006 |
Cell. Mol. Life Sci. |
pmid:16988788
|
Ryu J et al. |
Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling. |
2006 |
EMBO J. |
pmid:17124500
|
Hiraga Y et al. |
Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16631609
|
French KJ et al. |
Antitumor activity of sphingosine kinase inhibitors. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16632640
|
Milstien S and Spiegel S |
Targeting sphingosine-1-phosphate: a novel avenue for cancer therapeutics. |
2006 |
Cancer Cell |
pmid:16530698
|
Visentin B et al. |
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. |
2006 |
Cancer Cell |
pmid:16530706
|
Park KS et al. |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. |
2006 |
Mol. Pharmacol. |
pmid:16368894
|
Kang JS et al. |
Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways. |
2006 |
Mol. Pharmacol. |
pmid:16354764
|
Donati C and Bruni P |
Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. |
2006 |
Biochim. Biophys. Acta |
pmid:16890187
|
Thompson B et al. |
Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846783
|
Long JS et al. |
The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846788
|
Nagata Y et al. |
Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling. |
2006 |
J. Cell Biol. |
pmid:16847102
|
Xu R et al. |
Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. |
2006 |
FASEB J. |
pmid:16940153
|
von Wenckstern H et al. |
The role of the lysophospholipid sphingosine 1-phosphate in immune cell biology. |
2006 Jul-Aug |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:16830220
|
Herr DR and Chun J |
Effects of LPA and S1P on the nervous system and implications for their involvement in disease. |
2007 |
Curr Drug Targets |
pmid:17266539
|
Chun J |
Immunology. The sources of a lipid conundrum. |
2007 |
Science |
pmid:17431159
|
Sanchez T et al. |
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17431187
|
Jeng YJ et al. |
Progesterone-induced sphingosine kinase-1 expression in the rat uterus during pregnancy and signaling consequences. |
2007 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:17164439
|
Jang S et al. |
Cytochemical alterations in the rat retina by LPS administration. |
2007 |
Neurochem. Res. |
pmid:17160463
|
Harvey KA et al. |
Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation. |
2007 |
J. Cell. Physiol. |
pmid:17167780
|
Blondeau N et al. |
Distribution of sphingosine kinase activity and mRNA in rodent brain. |
2007 |
J. Neurochem. |
pmid:17623044
|
Giussani P et al. |
Sphingosine-1-phosphate and calcium signaling in cerebellar astrocytes and differentiated granule cells. |
2007 |
Neurochem. Res. |
pmid:17151916
|
Huwiler A and Zangemeister-Wittke U |
Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. |
2007 |
Crit. Rev. Oncol. Hematol. |
pmid:17560117
|
Pchejetski D et al. |
Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis. |
2007 |
Circ. Res. |
pmid:17158340
|
Omori K et al. |
Edaravone mimics sphingosine-1-phosphate-induced endothelial barrier enhancement in human microvascular endothelial cells. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17686998
|
Keul P et al. |
The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17158351
|
Walter DH et al. |
Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17158356
|
Phan VH et al. |
Disruption of sphingolipid metabolism elicits apoptosis-associated reproductive defects in Drosophila. |
2007 |
Dev. Biol. |
pmid:17706961
|
Mechtcheriakova D et al. |
Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses. |
2007 |
Cell. Signal. |
pmid:17113265
|
Fujiwara Y et al. |
Identification of the hydrophobic ligand binding pocket of the S1P1 receptor. |
2007 |
J. Biol. Chem. |
pmid:17114791
|
Ki SH et al. |
Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha. |
2007 |
J. Biol. Chem. |
pmid:17098744
|
Brahmbhatt VV et al. |
Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid. |
2007 |
Chem. Phys. Lipids |
pmid:17126823
|
Formigli L et al. |
Cytoskeleton/stretch-activated ion channel interaction regulates myogenic differentiation of skeletal myoblasts. |
2007 |
J. Cell. Physiol. |
pmid:17295211
|
Barthomeuf C |
Inhibition of S1P-induced angiogenesis, metastasis and inflammation by dietary polyphenols. |
2007 |
Free Radic. Biol. Med. |
pmid:17189837
|
Currie JC et al. |
MT1-MMP down-regulates the glucose 6-phosphate transporter expression in marrow stromal cells: a molecular link between pro-MMP-2 activation, chemotaxis, and cell survival. |
2007 |
J. Biol. Chem. |
pmid:17229722
|
Beech DJ |
Bipolar phospholipid sensing by TRPC5 calcium channel. |
2007 |
Biochem. Soc. Trans. |
pmid:17233612
|
Kunisawa J et al. |
Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production. |
2007 |
Blood |
pmid:17234743
|
Martino A et al. |
Sphingosine 1-phosphate interferes on the differentiation of human monocytes into competent dendritic cells. |
2007 |
Scand. J. Immunol. |
pmid:17212771
|
Johnstone ED et al. |
Epidermal growth factor and sphingosine-1-phosphate stimulate Na+/H+ exchanger activity in the human placental syncytiotrophoblast. |
2007 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:17913870
|
Hänel P et al. |
Erythrocytes store and release sphingosine 1-phosphate in blood. |
2007 |
FASEB J. |
pmid:17215483
|
Siow DL and Wattenberg BW |
An assay system for measuring the acute production of sphingosine 1-phosphate in intact monolayers. |
2007 |
Anal. Biochem. |
pmid:17884005
|
Gonzalez-Cabrera PJ et al. |
Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics. |
2007 |
J. Biol. Chem. |
pmid:17218309
|
Maceyka M et al. |
Measurement of mammalian sphingosine-1-phosphate phosphohydrolase activity in vitro and in vivo. |
2007 |
Meth. Enzymol. |
pmid:17954251
|
Igarashi J et al. |
Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins. |
2007 |
Br. J. Pharmacol. |
pmid:17220911
|
Maceyka M et al. |
Shooting the messenger: oxidative stress regulates sphingosine-1-phosphate. |
2007 |
Circ. Res. |
pmid:17204658
|
Maeda Y et al. |
Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3. |
2007 |
J. Immunol. |
pmid:17339438
|
Serriere-Lanneau V et al. |
The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. |
2007 |
FASEB J. |
pmid:17341687
|
Means CK et al. |
Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:17293497
|
Koh E et al. |
Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors. |
2007 |
Cancer Lett. |
pmid:17189669
|
Aoki S et al. |
The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3). |
2007 |
J. Thromb. Haemost. |
pmid:17403093
|
Novgorodov AS et al. |
Activation of sphingosine-1-phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration. |
2007 |
FASEB J. |
pmid:17255471
|
Masuko K et al. |
Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes. |
2007 |
BMC Musculoskelet Disord |
pmid:17374154
|
Young N and Van Brocklyn JR |
Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness. |
2007 |
Exp. Cell Res. |
pmid:17376432
|
Nakamura T et al. |
Synthesis and SAR studies of a novel class of S1P1 receptor antagonists. |
2007 |
Bioorg. Med. Chem. |
pmid:17379528
|
Zhao Y et al. |
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1. |
2007 |
J. Biol. Chem. |
pmid:17379599
|
Matsuo Y et al. |
Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation. |
2007 |
Atherosclerosis |
pmid:17118370
|
Nodai A et al. |
Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. |
2007 |
Life Sci. |
pmid:17382352
|
Baumruker T et al. |
FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis. |
2007 |
Expert Opin Investig Drugs |
pmid:17302523
|
Baran Y et al. |
Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells. |
2007 |
J. Biol. Chem. |
pmid:17303574
|
Chandru H and Boggaram V |
The role of sphingosine 1-phosphate in the TNF-alpha induction of IL-8 gene expression in lung epithelial cells. |
2007 |
Gene |
pmid:17306937
|
Jung ID et al. |
Sphingosine kinase inhibitor suppresses a Th1 polarization via the inhibition of immunostimulatory activity in murine bone marrow-derived dendritic cells. |
2007 |
Int. Immunol. |
pmid:17307797
|
Baranowski M et al. |
PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. |
2007 |
J. Physiol. Pharmacol. |
pmid:17440226
|
Gandolfo MT and Rabb H |
Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury. |
2007 |
Kidney Int. |
pmid:17554348
|
Keul P et al. |
HDL and its sphingosine-1-phosphate content in cardioprotection. |
2007 |
Heart Fail Rev |
pmid:17554629
|
Langlois S et al. |
Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. |
2007 |
Mol. Cancer Res. |
pmid:17541067
|
Sato K et al. |
HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17544365
|
Levine YC et al. |
Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. |
2007 |
J. Biol. Chem. |
pmid:17519230
|
Kimura T et al. |
[Measurement of sphingosine 1-phosphate as a biomarker of atherosclerosis]. |
2007 |
Rinsho Byori |
pmid:17511266
|
Baranowski M et al. |
Pioglitazone induces de novo ceramide synthesis in the rat heart. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17259076
|
Aoki S et al. |
Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17512899
|
Huang MC et al. |
Th17 augmentation in OTII TCR plus T cell-selective type 1 sphingosine 1-phosphate receptor double transgenic mice. |
2007 |
J. Immunol. |
pmid:17513728
|
Kontush A et al. |
Preferential sphingosine-1-phosphate enrichment and sphingomyelin depletion are key features of small dense HDL3 particles: relevance to antiapoptotic and antioxidative activities. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17569880
|
Rosen H et al. |
Tipping the gatekeeper: S1P regulation of endothelial barrier function. |
2007 |
Trends Immunol. |
pmid:17276731
|
Liao JJ et al. |
Cutting edge: Alternative signaling of Th17 cell development by sphingosine 1-phosphate. |
2007 |
J. Immunol. |
pmid:17442922
|
Choi CH et al. |
Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. |
2007 |
Arch. Pharm. Res. |
pmid:17489368
|
Donati C et al. |
Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts. |
2007 |
Stem Cells |
pmid:17464089
|
Naor MM et al. |
Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences. |
2007 |
J. Mol. Graph. Model. |
pmid:17467317
|
Ito K et al. |
Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17418101
|
Roztocil E et al. |
Sphingosine-1-phosphate-induced oxygen free radical generation in smooth muscle cell migration requires Galpha12/13 protein-mediated phospholipase C activation. |
2007 |
J. Vasc. Surg. |
pmid:18155002
|
Kurashima Y et al. |
Sphingosine 1-phosphate-mediated trafficking of pathogenic Th2 and mast cells for the control of food allergy. |
2007 |
J. Immunol. |
pmid:17641024
|
Kawanabe T et al. |
Sphingosine 1-phosphate accelerates wound healing in diabetic mice. |
2007 |
J. Dermatol. Sci. |
pmid:17643267
|
Suzuki H et al. |
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. |
2007 |
Toxicology |
pmid:17095132
|
Brizuela L et al. |
Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. |
2007 |
J. Lipid Res. |
pmid:17609523
|
Jin ZQ et al. |
A sphingosine kinase 1 mutation sensitizes the myocardium to ischemia/reperfusion injury. |
2007 |
Cardiovasc. Res. |
pmid:17610857
|
Karahatay S et al. |
Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis. |
2007 |
Cancer Lett. |
pmid:17619081
|
Oskeritzian CA et al. |
Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis. |
2007 |
Pharmacol. Ther. |
pmid:17669501
|
Xu M et al. |
Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17670896
|
Santucci MB et al. |
Sphingosine 1-phosphate promotes antigen processing and presentation to CD4+ T cells in Mycobacterium tuberculosis-infected monocytes. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17673170
|
Tao R et al. |
Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes. |
2007 |
Cardiovasc. Res. |
pmid:17320845
|
Roviezzo F et al. |
Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness. |
2007 |
Am. J. Respir. Cell Mol. Biol. |
pmid:17322125
|
Kajimoto T et al. |
Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons. |
2007 |
Mol. Cell. Biol. |
pmid:17325039
|
Nombela-Arrieta C et al. |
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. |
2007 |
J. Exp. Med. |
pmid:17325199
|
Osada M et al. |
Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells. |
2007 |
J. Biochem. |
pmid:17646176
|
Weigert A et al. |
Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. |
2007 |
Mol. Biol. Cell |
pmid:17652460
|
Lin CI et al. |
Sphingosine 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17331465
|
Kimura A et al. |
Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury. |
2007 |
Stem Cells |
pmid:16990586
|
Koh E et al. |
Sphingosine-1-phosphate initiates rapid retraction of pseudopodia by localized RhoA activation. |
2007 |
Cell. Signal. |
pmid:17307336
|
Torkhovskaya TI et al. |
Lysophospholipid receptors in cell signaling. |
2007 |
Biochemistry Mosc. |
pmid:17367289
|
Igarashi J et al. |
Hydrogen peroxide induces S1P1 receptors and sensitizes vascular endothelial cells to sphingosine 1-phosphate, a platelet-derived lipid mediator. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:16943246
|
Soares R and Azevedo I |
Inhibition of S1P by polyphenols prevents inflammation and angiogenesis: NFkappaB, a downstream effector? |
2007 |
Free Radic. Biol. Med. |
pmid:17189836
|