| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pulmonary Fibrosis | D011658 | 24 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ogle ME et al. | Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche. | 2017 | Stem Cells | pmid:28026131 |
| Yung BS et al. | Selective coupling of the S1P receptor subtype to S1P-mediated RhoA activation and cardioprotection. | 2017 | J. Mol. Cell. Cardiol. | pmid:28017639 |
| Contaifer D et al. | Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients. | 2017 | J. Lipid Res. | pmid:27993949 |
| Myśliwiec H et al. | Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. | 2017 | Arch. Dermatol. Res. | pmid:27988894 |
| Powell JA et al. | Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. | 2017 | Blood | pmid:27956387 |
| Miyabe C et al. | A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. | 2017 | Inflamm. Res. | pmid:27942751 |
| Pal SK et al. | A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. | 2017 | Cancer | pmid:27727447 |
| Vogt D and Stark H | Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. | 2017 | Med Res Rev | pmid:27480072 |
| Innamorati G et al. | Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. | 2017 | Cell Death Dis | pmid:28703804 |
| Bougault C et al. | Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. | 2017 | Bone | pmid:28684192 |
| Tsai CH et al. | Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. | 2017 | Mol Oncol | pmid:28672103 |
| Schmidt KG et al. | Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study. | 2017 | Front Immunol | pmid:29033951 |
| Xie Z et al. | Targeting sphingosine-1-phosphate signaling for cancer therapy. | 2017 | Sci China Life Sci | pmid:28623546 |
| Yanagida K et al. | Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:28396408 |
| Takahashi C et al. | Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. | 2017 | J. Atheroscler. Thromb. | pmid:28321011 |
| Pierucci F et al. | Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. | 2017 | Neuropharmacology | pmid:28077289 |
| Leo A et al. | The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. | 2017 | CNS Neurol Disord Drug Targets | pmid:27823573 |
| Roch L et al. | High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. | 2017 | Mol. Neurobiol. | pmid:27631876 |
| Vu TM et al. | Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. | 2017 | Nature | pmid:29045386 |
| Reinhard NR et al. | The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. | 2017 | Mol. Biol. Cell | pmid:28954861 |
| Natarajan V et al. | Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. | 2017 | BMC Genomics | pmid:28851267 |
| Hajny S and Christoffersen C | A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. | 2017 | Int J Mol Sci | pmid:28749426 |
| Bertlich M et al. | Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. | 2017 | Otol. Neurotol. | pmid:28742634 |
| Koch A et al. | Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients. | 2017 | Int J Mol Sci | pmid:28714882 |
| Alqinyah M et al. | Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity. | 2017 | Mol. Pharmacol. | pmid:28031332 |
| Ebenezer DL et al. | Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. | 2017 | Adv Biol Regul | pmid:27720306 |
| Chen T et al. | Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. | 2017 | Front Biosci (Landmark Ed) | pmid:27814635 |
| Beider K et al. | The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway. | 2017 | Clin. Cancer Res. | pmid:27697999 |
| Thieme M et al. | Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. | 2017 | Exp. Dermatol. | pmid:27574180 |
| Chang N et al. | HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. | 2017 | J. Mol. Med. | pmid:27543493 |
| Gudipaty SA and Rosenblatt J | Epithelial cell extrusion: Pathways and pathologies. | 2017 | Semin. Cell Dev. Biol. | pmid:27212253 |
| Du Y et al. | Exosomes from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells (hiPSC-MSCs) Protect Liver against Hepatic Ischemia/ Reperfusion Injury via Activating Sphingosine Kinase and Sphingosine-1-Phosphate Signaling Pathway. | 2017 | Cell. Physiol. Biochem. | pmid:28934733 |
| Kuchler L et al. | Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis. | 2017 | Mol. Immunol. | pmid:28846923 |
| Nicholas SE et al. | Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. | 2017 | PLoS ONE | pmid:28806736 |
| Lee SY et al. | Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. | 2017 | Diabetes | pmid:28698261 |
| Hutami IR et al. | Fas/S1P crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28687489 |
| Cannavo A et al. | β-Blockade Prevents Post-Ischemic Myocardial Decompensation Via βAR-Dependent Protective Sphingosine-1 Phosphate Signaling. | 2017 | J. Am. Coll. Cardiol. | pmid:28683966 |
| Punsawad C and Viriyavejakul P | Reduction in serum sphingosine 1-phosphate concentration in malaria. | 2017 | PLoS ONE | pmid:28666023 |
| Luo J et al. | The effects of berberine on a murine model of multiple sclerosis and the SPHK1/S1P signaling pathway. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28655617 |
| Chang CH and Randolph GJ | Sphingosine-1-Phosphate as the Lymphocyte's Ticket to Ride and Survive. | 2017 | Dev. Cell | pmid:28633013 |
| Fang R et al. | Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3β Phosphorylation. | 2017 | Arch. Med. Res. | pmid:28625317 |
| Rohrbach T et al. | Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology. | 2017 | Crit. Rev. Biochem. Mol. Biol. | pmid:28618839 |
| Vijayan M et al. | Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. | 2017 | J. Immunol. | pmid:28600291 |
| Navarrete A et al. | A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. | 2017 | J Pharm Biomed Anal | pmid:28314215 |
| Shirakawa H et al. | Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. | 2017 | Glia | pmid:28300348 |
| Dyckman AJ | Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P) Agonists and Future Perspectives. | 2017 | J. Med. Chem. | pmid:28291340 |
| Nielsen OH et al. | Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease. | 2017 | Trends Mol Med | pmid:28283249 |
| Peyrin-Biroulet L et al. | Modulation of sphingosine-1-phosphate in inflammatory bowel disease. | 2017 | Autoimmun Rev | pmid:28279838 |
| Miller M et al. | Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. | 2017 | J. Immunol. | pmid:28275141 |
| Tafelmeier M et al. | Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27163393 |
| Su K et al. | FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines. | 2017 | Mediators Inflamm. | pmid:28270699 |
| Serafimidis I et al. | Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. | 2017 | PLoS Biol. | pmid:28248965 |
| Lee HM et al. | Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. | 2017 | J. Pathol. | pmid:28240350 |
| Rieck M et al. | Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. | 2017 | Eur. J. Immunol. | pmid:28198542 |
| Bruno M et al. | Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. | 2017 | Biochim. Biophys. Acta | pmid:28188805 |
| Fu P et al. | Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. | 2016 | J. Biol. Chem. | pmid:27864331 |
| Wang X et al. | Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier. | 2016 | PLoS Pathog. | pmid:27711202 |
| Adamiak M et al. | The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells. | 2016 | Stem Cell Rev | pmid:27704316 |
| Morillon YM et al. | Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. | 2016 | J. Immunol. | pmid:27694496 |
| Lepannetier S et al. | Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. | 2016 | Cell Calcium | pmid:27638096 |
| Kemppainen K et al. | Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. | 2016 | Cell. Signal. | pmid:27634386 |
| Liu X et al. | ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. | 2016 | J. Physiol. Biochem. | pmid:27377933 |
| Egom EE et al. | Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. | 2016 | Mol. Cell. Biochem. | pmid:27372350 |
| Sanagawa A et al. | Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. | 2016 | Mol Med Rep | pmid:27357063 |
| Tiper IV et al. | Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. | 2016 | Pathog Dis | pmid:27354294 |
| Jung M et al. | Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis. | 2016 | Sci Signal | pmid:27353364 |
| Rodvold JJ and Zanetti M | Tumor microenvironment on the move and the Aselli connection. | 2016 | Sci Signal | pmid:27353363 |
| Harijith A et al. | Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27343196 |
| Tong S et al. | Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. | 2016 | J. Biol. Chem. | pmid:27405756 |
| Anbazhagan AN et al. | Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate. | 2016 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:27079615 |
| Koresawa R et al. | Sphingosine-1-phosphate receptor 1 as a prognostic biomarker and therapeutic target for patients with primary testicular diffuse large B-cell lymphoma. | 2016 | Br. J. Haematol. | pmid:27061580 |
| Resop RS et al. | Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human TÂ cells from the thymus to the periphery. | 2016 | J. Allergy Clin. Immunol. | pmid:27056271 |
| Guo J et al. | Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). | 2016 | Bioorg. Med. Chem. Lett. | pmid:27055941 |
| Adams DR et al. | Sphingosine Kinases: Emerging Structure-Function Insights. | 2016 | Trends Biochem. Sci. | pmid:27021309 |
| Lv M et al. | Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion. | 2016 | Inflamm. Res. | pmid:27002656 |
| Wang H et al. | Potential serum biomarkers from a metabolomics study of autism. | 2016 | J Psychiatry Neurosci | pmid:26395811 |
| Frej C et al. | Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. | 2016 | J. Cell. Mol. Med. | pmid:26990127 |
| Pyne S et al. | Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances. | 2016 | Prog. Lipid Res. | pmid:26970273 |
| Pászti-Gere E et al. | Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. | 2016 | Oxid Med Cell Longev | pmid:26823955 |
| Wiltshire R et al. | Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. | 2016 | Sci Rep | pmid:26813587 |
| Farez MF and Correale J | Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. | 2016 | J. Neurol. Sci. | pmid:26810518 |
| Santos-Cortez RL et al. | Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2. | 2016 | Am. J. Hum. Genet. | pmid:26805784 |
| Bock S et al. | Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. | 2016 | J. Dermatol. Sci. | pmid:26803226 |
| Marycz K et al. | The influence of metal-based biomaterials functionalized with sphingosine-1-phosphate on the cellular response and osteogenic differentaion potenial of human adipose derived mesenchymal stem cells in vitro. | 2016 | J Biomater Appl | pmid:26801473 |
| Tran HB et al. | Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. | 2016 | J. Leukoc. Biol. | pmid:26792820 |
| Chapurlat RD and Confavreux CB | Novel biological markers of bone: from bone metabolism to bone physiology. | 2016 | Rheumatology (Oxford) | pmid:26790456 |
| Rana A and Sharma S | Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. | 2016 | Clin. Exp. Pharmacol. Physiol. | pmid:26582369 |
| Yuasa D et al. | C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart. | 2016 | FASEB J. | pmid:26578687 |
| Realini N et al. | Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. | 2016 | J. Biol. Chem. | pmid:26553872 |
| Cheng JC et al. | Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. | 2016 | Cell. Signal. | pmid:26994820 |
| Ratajczak MZ and Suszynska M | Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells. | 2016 | Stem Cell Rev | pmid:26400757 |
| Zhang L et al. | Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. | 2016 | Microcirculation | pmid:27015105 |
| Yaghobian D et al. | Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. | 2016 | Clin. Exp. Pharmacol. Physiol. | pmid:26414003 |
| Bae SJ et al. | The circulating sphingosine-1-phosphate level predicts incident fracture in postmenopausal women: a 3.5-year follow-up observation study. | 2016 | Osteoporos Int | pmid:26984570 |
| Kalhori V et al. | FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. | 2016 | Endocr. Relat. Cancer | pmid:26935838 |
| Setoguchi R | IL-15 boosts the function and migration of human terminally differentiated CD8+ T cells by inducing a unique gene signature. | 2016 | Int. Immunol. | pmid:26857736 |
| Nojima H et al. | Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. | 2016 | J. Hepatol. | pmid:26254847 |
| Kim BJ et al. | The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. | 2016 | J. Endocrinol. Invest. | pmid:26219613 |
| Touat-Hamici Z et al. | Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. | 2016 | Cardiovasc. Res. | pmid:27694435 |
| Medina CB and Ravichandran KS | Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. | 2016 | Cell Death Differ. | pmid:26891690 |