Kulinski JM et al. |
Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. |
2016 |
Eur. J. Pharmacol. |
pmid:25941085
|
Silva VR et al. |
Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise. |
2016 |
Aging (Albany NY) |
pmid:28039439
|
Lei YC et al. |
C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure. |
2016 |
World J. Gastroenterol. |
pmid:28028363
|
Al Fadel F et al. |
Involvement of Sphingosine 1-Phosphate in Palmitate-Induced Non-Alcoholic Fatty Liver Disease. |
2016 |
Cell. Physiol. Biochem. |
pmid:28006772
|
Terashita T et al. |
Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. |
2016 |
Respir. Res. |
pmid:27829417
|
Brait VH et al. |
Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice. |
2016 |
Stroke |
pmid:27827329
|
Zamora-Pineda J et al. |
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. |
2016 |
J. Exp. Med. |
pmid:27810923
|
Kobayashi N et al. |
Fluorescence-based rapid measurement of sphingosine-1-phosphate transport activity in erythrocytes. |
2016 |
J. Lipid Res. |
pmid:27655910
|
Evangelisti C et al. |
Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies. |
2016 |
Leukemia |
pmid:27461062
|
Stolwijk JA et al. |
Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function. |
2016 |
J. Biol. Chem. |
pmid:27624938
|
Gharbaran R |
Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma. |
2016 |
Tumour Biol. |
pmid:27317256
|
Higashi K et al. |
Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts. |
2016 |
Bone |
pmid:27612439
|
Sasset L et al. |
Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. |
2016 |
Trends Endocrinol. Metab. |
pmid:27562337
|
Roviezzo F et al. |
Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate. |
2016 |
Pharmacol. Res. |
pmid:27713021
|
Hemdan NY et al. |
Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsis. |
2016 |
Eur. J. Immunol. |
pmid:27683081
|
Chew WS et al. |
To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling. |
2016 |
Pharmacol. Res. |
pmid:27663260
|
Wang X et al. |
Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier. |
2016 |
PLoS Pathog. |
pmid:27711202
|
Adamiak M et al. |
The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells. |
2016 |
Stem Cell Rev |
pmid:27704316
|
Morillon YM et al. |
Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. |
2016 |
J. Immunol. |
pmid:27694496
|
Lepannetier S et al. |
Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. |
2016 |
Cell Calcium |
pmid:27638096
|
Kemppainen K et al. |
Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. |
2016 |
Cell. Signal. |
pmid:27634386
|
Custódio R et al. |
Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei. |
2016 |
Mol. Microbiol. |
pmid:27632710
|
Ebenezer DL et al. |
Targeting sphingosine-1-phosphate signaling in lung diseases. |
2016 |
Pharmacol. Ther. |
pmid:27621206
|
Tsuchida J et al. |
Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis. |
2016 |
J. Surg. Res. |
pmid:27621003
|
Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
pmid:27467777
|
Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
pmid:27459945
|
Poissonnier A et al. |
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. |
2016 |
Immunity |
pmid:27438772
|
Zhang Q et al. |
Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. |
2016 |
Am. J. Chin. Med. |
pmid:27430910
|
Adamiak M et al. |
Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. |
2016 |
Cell Transplant |
pmid:27412411
|
Liu X et al. |
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. |
2016 |
J. Physiol. Biochem. |
pmid:27377933
|
Egom EE et al. |
Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes. |
2016 |
Mol. Cell. Biochem. |
pmid:27372350
|
Sanagawa A et al. |
Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. |
2016 |
Mol Med Rep |
pmid:27357063
|
Tiper IV et al. |
Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. |
2016 |
Pathog Dis |
pmid:27354294
|
Jung M et al. |
Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis. |
2016 |
Sci Signal |
pmid:27353364
|
Rodvold JJ and Zanetti M |
Tumor microenvironment on the move and the Aselli connection. |
2016 |
Sci Signal |
pmid:27353363
|
Harijith A et al. |
Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. |
2016 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:27343196
|
Hernández-Coronado CG et al. |
Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. |
2016 |
Gen. Comp. Endocrinol. |
pmid:27342378
|
Chakrabarti SS et al. |
Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease. |
2016 |
Curr Alzheimer Res |
pmid:27335046
|
Fleming JK et al. |
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. |
2016 |
J. Lipid Res. |
pmid:27444045
|
Tong S et al. |
Structural Insight into Substrate Selection and Catalysis of Lipid Phosphate Phosphatase PgpB in the Cell Membrane. |
2016 |
J. Biol. Chem. |
pmid:27405756
|
Nagura Y et al. |
Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. |
2016 |
Transfus Med |
pmid:27350440
|
Sanchez T |
Sphingosine-1-Phosphate Signaling in Endothelial Disorders. |
2016 |
Curr Atheroscler Rep |
pmid:27115142
|
Crespo I et al. |
Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. |
2016 |
J. Pineal Res. |
pmid:27101794
|
Riganti L et al. |
Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. |
2016 |
J. Neurosci. |
pmid:27098703
|
Cai Y et al. |
FOXF1 maintains endothelial barrier function and prevents edema after lung injury. |
2016 |
Sci Signal |
pmid:27095594
|
Castaldi A et al. |
Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs. |
2016 |
Cell. Signal. |
pmid:27094722
|
Anbazhagan AN et al. |
Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate. |
2016 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:27079615
|
Koresawa R et al. |
Sphingosine-1-phosphate receptor 1 as a prognostic biomarker and therapeutic target for patients with primary testicular diffuse large B-cell lymphoma. |
2016 |
Br. J. Haematol. |
pmid:27061580
|
Resop RS et al. |
Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human TÂ cells from the thymus to the periphery. |
2016 |
J. Allergy Clin. Immunol. |
pmid:27056271
|
Guo J et al. |
Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). |
2016 |
Bioorg. Med. Chem. Lett. |
pmid:27055941
|
Trinh HK et al. |
Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. |
2016 |
Sci Rep |
pmid:27830727
|
Adams DR et al. |
Sphingosine Kinases: Emerging Structure-Function Insights. |
2016 |
Trends Biochem. Sci. |
pmid:27021309
|
Lv M et al. |
Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion. |
2016 |
Inflamm. Res. |
pmid:27002656
|
Wang H et al. |
Potential serum biomarkers from a metabolomics study of autism. |
2016 |
J Psychiatry Neurosci |
pmid:26395811
|
Frej C et al. |
Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. |
2016 |
J. Cell. Mol. Med. |
pmid:26990127
|
Pyne S et al. |
Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances. |
2016 |
Prog. Lipid Res. |
pmid:26970273
|
Zhang H et al. |
Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. |
2016 |
Sci Rep |
pmid:27476912
|
Aoki M et al. |
Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential. |
2016 |
Mediators Inflamm. |
pmid:26966342
|
Brinck JW et al. |
Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. |
2016 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:26966278
|
Luo B et al. |
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
2016 |
Immunity |
pmid:26872696
|
Li J et al. |
Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway. |
2016 |
Tumour Biol. |
pmid:26857281
|
Camaré C et al. |
The neutral sphingomyelinase-2 is involved in angiogenic signaling triggered by oxidized LDL. |
2016 |
Free Radic. Biol. Med. |
pmid:26855418
|
Kim SE et al. |
The Role of Sphingosine-1-Phosphate in Adipogenesis of Graves' Orbitopathy. |
2016 |
Invest. Ophthalmol. Vis. Sci. |
pmid:26830367
|
Messias CV et al. |
Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation. |
2016 |
PLoS ONE |
pmid:26824863
|
Pászti-Gere E et al. |
Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status. |
2016 |
Oxid Med Cell Longev |
pmid:26823955
|
Wiltshire R et al. |
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. |
2016 |
Sci Rep |
pmid:26813587
|
Farez MF and Correale J |
Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. |
2016 |
J. Neurol. Sci. |
pmid:26810518
|
Santos-Cortez RL et al. |
Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2. |
2016 |
Am. J. Hum. Genet. |
pmid:26805784
|
Bock S et al. |
Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. |
2016 |
J. Dermatol. Sci. |
pmid:26803226
|
Marycz K et al. |
The influence of metal-based biomaterials functionalized with sphingosine-1-phosphate on the cellular response and osteogenic differentaion potenial of human adipose derived mesenchymal stem cells in vitro. |
2016 |
J Biomater Appl |
pmid:26801473
|
Tran HB et al. |
Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. |
2016 |
J. Leukoc. Biol. |
pmid:26792820
|
Chapurlat RD and Confavreux CB |
Novel biological markers of bone: from bone metabolism to bone physiology. |
2016 |
Rheumatology (Oxford) |
pmid:26790456
|
Zhang Y et al. |
Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. |
2016 |
PLoS ONE |
pmid:26788916
|
Dillmann C et al. |
S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. |
2016 |
J. Immunol. |
pmid:26783340
|
Ghasemi R et al. |
Integrated sphingosine-1 phosphate signaling in the central nervous system: From physiological equilibrium to pathological damage. |
2016 |
Pharmacol. Res. |
pmid:26772814
|
Maczis M et al. |
Sphingosine-1-phosphate and estrogen signaling in breast cancer. |
2016 |
Adv Biol Regul |
pmid:26601898
|
Zhang F et al. |
Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. |
2016 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:26589326
|
Pyne NJ and Tigyi GJ |
A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research. |
2016 |
Prog. Lipid Res. |
pmid:26584871
|
Rana A and Sharma S |
Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
pmid:26582369
|
Yuasa D et al. |
C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart. |
2016 |
FASEB J. |
pmid:26578687
|
Gao D et al. |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26859520
|
Realini N et al. |
Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. |
2016 |
J. Biol. Chem. |
pmid:26553872
|
Campos LS et al. |
Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling. |
2016 |
Mol. Cell. Biol. |
pmid:26552704
|
Nagahashi M et al. |
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. |
2016 |
J Mammary Gland Biol Neoplasia |
pmid:27194029
|
Patmanathan SN et al. |
Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2. |
2016 |
Sci Rep |
pmid:27160553
|
Li N and Zhang F |
Implication of sphingosin-1-phosphate in cardiovascular regulation. |
2016 |
Front Biosci (Landmark Ed) |
pmid:27100508
|
Cheng JC et al. |
Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. |
2016 |
Cell. Signal. |
pmid:26994820
|
Ratajczak MZ and Suszynska M |
Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells. |
2016 |
Stem Cell Rev |
pmid:26400757
|
Arish M et al. |
Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. |
2016 |
Drug Discov. Today |
pmid:26456576
|
Zhang L et al. |
Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. |
2016 |
Microcirculation |
pmid:27015105
|
Yaghobian D et al. |
Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. |
2016 |
Clin. Exp. Pharmacol. Physiol. |
pmid:26414003
|
Bae SJ et al. |
The circulating sphingosine-1-phosphate level predicts incident fracture in postmenopausal women: a 3.5-year follow-up observation study. |
2016 |
Osteoporos Int |
pmid:26984570
|
Kalhori V et al. |
FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. |
2016 |
Endocr. Relat. Cancer |
pmid:26935838
|
Liu X et al. |
Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. |
2016 |
Exp. Biol. Med. (Maywood) |
pmid:26376826
|
Setoguchi R |
IL-15 boosts the function and migration of human terminally differentiated CD8+ T cells by inducing a unique gene signature. |
2016 |
Int. Immunol. |
pmid:26857736
|
Kurano M et al. |
Resveratrol exerts a biphasic effect on apolipoprotein M. |
2016 |
Br. J. Pharmacol. |
pmid:26445217
|
Nojima H et al. |
Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. |
2016 |
J. Hepatol. |
pmid:26254847
|
Kim BJ et al. |
The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. |
2016 |
J. Endocrinol. Invest. |
pmid:26219613
|
Touat-Hamici Z et al. |
Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. |
2016 |
Cardiovasc. Res. |
pmid:27694435
|
Medina CB and Ravichandran KS |
Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. |
2016 |
Cell Death Differ. |
pmid:26891690
|