Rosenfeldt HM et al. |
EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. |
2001 |
FASEB J. |
pmid:11726541
|
Lampasso JD et al. |
Sphingosine-1-phosphate effects on PKC isoform expression in human osteoblastic cells. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728164
|
Hla T et al. |
Lysophospholipids--receptor revelations. |
2001 |
Science |
pmid:11729304
|
Muraki K and Imaizumi Y |
A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells. |
2001 |
J. Physiol. (Lond.) |
pmid:11731576
|
Lee MJ et al. |
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. |
2001 |
Mol. Cell |
pmid:11583630
|
Li G et al. |
Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum. |
2001 |
Development |
pmid:11566853
|
Bischoff A et al. |
Nifedipine inhibits sphinogosine-1-phosphate-induced renovascular contraction in vitro and in vivo. |
2001 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:11534858
|
Robert P et al. |
EDG1 receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes. |
2001 |
J. Mol. Cell. Cardiol. |
pmid:11549339
|
Marletta MA |
Another activation switch for endothelial nitric oxide synthase: why does it have to be so complicated? |
2001 |
Trends Biochem. Sci. |
pmid:11551775
|
Erl W and Siess W |
Sphingosine-1-phosphate and the leading Edg-1 of vascular smooth muscle cells. |
2001 |
Circ. Res. |
pmid:11557732
|
Kluk MJ and Hla T |
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. |
2001 |
Circ. Res. |
pmid:11557736
|
Meacci E et al. |
Dual regulation of sphingosine 1-phosphate-induced phospholipase D activity through RhoA and protein kinase C-alpha in C2C12 myoblasts. |
2001 |
Cell. Signal. |
pmid:11483412
|
Pébay A et al. |
Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades. |
2001 |
Eur. J. Neurosci. |
pmid:11467306
|
Andor A et al. |
YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells. |
2001 |
Cell. Microbiol. |
pmid:11298653
|
Ammit AJ et al. |
Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. |
2001 |
FASEB J. |
pmid:11344091
|
Yatomi Y et al. |
Sphingosine 1-phosphate: synthesis and release. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324700
|
Goetzl EJ |
Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324701
|
Olivera A and Spiegel S |
Sphingosine kinase: a mediator of vital cellular functions. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324702
|
Hla T |
Sphingosine 1-phosphate receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324703
|
Mandala SM |
Sphingosine-1-phosphate phosphatases. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324704
|
Lynch KR and Macdonald TL |
Structure activity relationships of lysophospholipid mediators. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324706
|
Panetti TS et al. |
Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324710
|
Alderton F et al. |
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells. |
2001 |
J. Biol. Chem. |
pmid:11278307
|
Igarashi J et al. |
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278407
|
Morales-Ruiz M et al. |
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278592
|
Birchwood CJ et al. |
Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. |
2001 |
J. Biol. Chem. |
pmid:11278643
|
Takuwa Y et al. |
Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11377814
|
Nanjundan M and Possmayer F |
Characterization of the pulmonary N-ethylmaleimide-insensitive phosphatidate phosphohydrolase. |
2000 Jul-Aug |
Exp. Lung Res. |
pmid:10914334
|
Vasta V et al. |
Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells. |
2000 |
Biochim. Biophys. Acta |
pmid:10601704
|
An S et al. |
Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. |
2000 |
J. Biol. Chem. |
pmid:10617617
|
Pyne S and Pyne N |
Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors. |
2000 |
Pharmacol. Ther. |
pmid:11150592
|
Conway A et al. |
Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells. |
2000 |
Cell. Signal. |
pmid:11152959
|
Sato K et al. |
Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells. |
2000 |
Brain Res. Mol. Brain Res. |
pmid:11146117
|
Spiegel S and Milstien S |
Functions of a new family of sphingosine-1-phosphate receptors. |
2000 |
Biochim. Biophys. Acta |
pmid:10760461
|
Panetti TS et al. |
Sphingosine-1-phosphate and lysophosphatidic acid stimulate endothelial cell migration. |
2000 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:10764666
|
Boguslawski G et al. |
Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10833459
|
Kimura T et al. |
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. |
2000 |
Biochem. J. |
pmid:10794715
|
Van Brocklyn JR et al. |
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. |
2000 |
Blood |
pmid:10753843
|
English D et al. |
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. |
2000 |
FASEB J. |
pmid:11053247
|
Edsall L et al. |
Enzymatic method for measurement of sphingosine 1-phosphate. |
2000 |
Meth. Enzymol. |
pmid:11070858
|
Sullards MC |
Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry. |
2000 |
Meth. Enzymol. |
pmid:11070861
|
Young KW et al. |
Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production. Potential involvement of endogenous EDG-4 receptors. |
2000 |
J. Biol. Chem. |
pmid:10954727
|
Peyruchaud O and Mosher DF |
Differential stimulation of signaling pathways initiated by Edg-2 in response to lysophosphatidic acid or sphingosine-1-phosphate. |
2000 |
Cell. Mol. Life Sci. |
pmid:10961347
|
Casper RF and Jurisicova A |
Protecting the female germ line from cancer therapy. |
2000 |
Nat. Med. |
pmid:11017136
|
Morita Y et al. |
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. |
2000 |
Nat. Med. |
pmid:11017141
|
Himmel HM et al. |
Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes. |
2000 |
Mol. Pharmacol. |
pmid:10908314
|
Driever W |
Developmental biology. Bringing two hearts together. |
2000 |
Nature |
pmid:10910341
|
Kupperman E et al. |
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. |
2000 |
Nature |
pmid:10910360
|
Mandala SM et al. |
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10859351
|
Murata N et al. |
Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay. |
2000 |
Anal. Biochem. |
pmid:10860507
|