Radi ZA and Vogel MW |
Gastric parietal cell atrophy and depletion after administration of a sphingosine-1-phosphate 1 inhibitor. |
2014 |
Toxicol Pathol |
pmid:24178572
|
Yu Y et al. |
Phospholipid transfer protein deficiency decreases the content of S1P in HDL via the loss of its transfer capability. |
2014 |
Lipids |
pmid:24158769
|
Giannouli CC et al. |
Visualizing S1P-directed cellular egress by intravital imaging. |
2014 |
Biochim. Biophys. Acta |
pmid:24090699
|
Zhang Y et al. |
Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression. |
2014 |
J. Clin. Invest. |
pmid:24837436
|
Kurano M et al. |
Induction of insulin secretion by apolipoprotein M, a carrier for sphingosine 1-phosphate. |
2014 |
Biochim. Biophys. Acta |
pmid:24814049
|
Arya D et al. |
Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. |
2014 |
J. Biomed. Sci. |
pmid:24898615
|
Maceyka M and Spiegel S |
Sphingolipid metabolites in inflammatory disease. |
2014 |
Nature |
pmid:24899305
|
Nagata Y et al. |
Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation. |
2014 |
Exp. Cell Res. |
pmid:24960577
|
Ceccom J et al. |
[Sphingosine 1-phosphate as a biomarker for Alzheimer's disease?]. |
2014 |
Med Sci (Paris) |
pmid:24939530
|
Kang JW and Lee SM |
Impaired expression of caveolin-1 contributes to hepatic ischemia and reperfusion injury. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24997335
|
Ohotski J et al. |
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor-4. |
2014 |
Cell. Signal. |
pmid:24486401
|
Snider AJ et al. |
Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. |
2014 |
PLoS ONE |
pmid:25460165
|
Takeo T et al. |
Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. |
2014 |
Cryobiology |
pmid:24201107
|
de Assuncao TM et al. |
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. |
2014 |
J. Biol. Chem. |
pmid:24759103
|
Nakanaga K et al. |
Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. |
2014 |
J. Biochem. |
pmid:24451492
|
Tibboel J et al. |
Sphingolipids in lung growth and repair. |
2014 |
Chest |
pmid:24394822
|
Kim YI et al. |
An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production. |
2014 |
Mol. Cell. Biol. |
pmid:25312644
|
Keller J et al. |
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. |
2014 |
Nat Commun |
pmid:25333900
|
Lepletier A et al. |
Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease. |
2014 |
PLoS Negl Trop Dis |
pmid:25330249
|
Bradley E et al. |
Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
2014 |
PLoS ONE |
pmid:25330231
|
Xu H et al. |
Sphingosine-1-phosphate receptor agonist, FTY720, restores coronary flow reserve in diabetic rats. |
2014 |
Circ. J. |
pmid:25319164
|
Fukui H et al. |
S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish. |
2014 |
Dev. Cell |
pmid:25313964
|
Obinata H et al. |
Individual variation of human S1Pâ‚ coding sequence leads to heterogeneity in receptor function and drug interactions. |
2014 |
J. Lipid Res. |
pmid:25293589
|
Fernández-Pisonero I et al. |
Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells. |
2014 |
PLoS ONE |
pmid:25275309
|
Sassoli C et al. |
Mesenchymal stromal cell secreted sphingosine 1-phosphate (S1P) exerts a stimulatory effect on skeletal myoblast proliferation. |
2014 |
PLoS ONE |
pmid:25264785
|
Silva VR et al. |
Hypothalamic S1P/S1PR1 axis controls energy homeostasis. |
2014 |
Nat Commun |
pmid:25255053
|
Hirata N et al. |
Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation. |
2014 |
Nat Commun |
pmid:25254944
|
Bigaud M et al. |
Second generation S1P pathway modulators: research strategies and clinical developments. |
2014 |
Biochim. Biophys. Acta |
pmid:24239768
|
Huang YL et al. |
Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. |
2014 |
Cell. Signal. |
pmid:24333325
|
Emery SM et al. |
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:24259678
|
Adamson RH et al. |
Albumin modulates S1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect. |
2014 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:24531813
|
Rosen H et al. |
The organization of the sphingosine 1-phosphate signaling system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728591
|
Hanson MA and Peach R |
Structural biology of the S1P1 receptor. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728592
|
Cahalan SM |
Chemical and genetic tools to explore S1P biology. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728593
|
Arnon TI and Cyster JG |
Blood, sphingosine-1-phosphate and lymphocyte migration dynamics in the spleen. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728595
|
Oldstone MB and Rosen H |
Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728596
|
Martin R and Sospedra M |
Sphingosine-1 phosphate and central nervous system. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728597
|
Ogle ME et al. |
Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. |
2014 |
Acta Biomater |
pmid:25128750
|
Bi Y et al. |
Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. |
2014 |
Am. J. Pathol. |
pmid:25111230
|
Ishitsuka A et al. |
FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression. |
2014 |
Int. J. Mol. Med. |
pmid:25109763
|
Xiong H et al. |
SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling. |
2014 |
Oncol. Rep. |
pmid:25109605
|
Rolin J and Maghazachi AA |
Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. |
2014 |
J. Leukoc. Biol. |
pmid:24493826
|
Zhao X et al. |
Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:25106095
|
Li MH et al. |
Induction of chemokine (C-C motif) ligand 2 by sphingosine-1-phosphate signaling in neuroblastoma. |
2014 |
J. Pediatr. Surg. |
pmid:25092091
|
Awojoodu AO et al. |
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. |
2014 |
Blood |
pmid:25075126
|
Belvitch P et al. |
Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics. |
2014 |
Microvasc. Res. |
pmid:25072537
|
Mendes-da-Cruz DA et al. |
Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors. |
2014 |
PLoS ONE |
pmid:25068647
|
Xiong Y and Hla T |
S1P control of endothelial integrity. |
2014 |
Curr. Top. Microbiol. Immunol. |
pmid:24728594
|
Mendelson K et al. |
Sphingosine 1-phosphate signalling. |
2014 |
Development |
pmid:24346695
|
Hait NC et al. |
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. |
2014 |
Nat. Neurosci. |
pmid:24859201
|
Rahman MM et al. |
Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. |
2014 |
PLoS ONE |
pmid:24647471
|
Park SM et al. |
Sphingosine-1-phosphate lyase is expressed by CD68+ cells on the parenchymal side of marginal reticular cells in human lymph nodes. |
2014 |
Eur. J. Immunol. |
pmid:24825162
|
Simmons S and Ishii M |
Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity. |
2014 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:24276789
|
Snelder N et al. |
Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation. |
2014 |
Drug Metab. Dispos. |
pmid:24965813
|
Tarbell JM et al. |
Mechanosensing at the vascular interface. |
2014 |
Annu Rev Biomed Eng |
pmid:24905872
|
Potì F et al. |
Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). |
2014 |
Cardiovasc. Res. |
pmid:24891400
|
Chawla S et al. |
Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. |
2014 |
PLoS ONE |
pmid:24887065
|
Janes K et al. |
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. |
2014 |
J. Biol. Chem. |
pmid:24876379
|
Yan W et al. |
Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. |
2014 |
J. Mol. Cell. Cardiol. |
pmid:24852843
|
Sheridan GK and Dev KK |
Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations. |
2014 |
Sci Rep |
pmid:24851861
|
Ni X et al. |
Interaction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancement. |
2014 |
J. Cell. Biochem. |
pmid:24851274
|
Vanoli E et al. |
Vagomimetic effects of fingolimod: physiology and clinical implications. |
2014 |
CNS Neurosci Ther |
pmid:24836740
|
Zhang GQ et al. |
Sphingosine-1-phosphate receptors respond differently to early myocardial ischemia and ischemia-reperfusion in vivo. |
2014 |
Sheng Li Xue Bao |
pmid:24777407
|
Smyth SS et al. |
Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. |
2014 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:24482375
|
Takabe K and Spiegel S |
Export of sphingosine-1-phosphate and cancer progression. |
2014 |
J. Lipid Res. |
pmid:24474820
|
Ishizawa S et al. |
Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor. |
2014 |
Clin. Exp. Nephrol. |
pmid:24463961
|
Couttas TA et al. |
Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease pathogenesis. |
2014 |
Acta Neuropathol Commun |
pmid:24456642
|
Gassowska M et al. |
Sphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells. |
2014 |
Neurochem. Res. |
pmid:24452756
|
Borge M et al. |
The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406. |
2014 |
J. Immunol. |
pmid:25127862
|
Fujii K et al. |
Sphingosine 1-phosphate increases an intracellular Ca(2+) concentration via S1P3 receptor in cultured vascular smooth muscle cells. |
2014 |
J. Pharm. Pharmacol. |
pmid:24450400
|
Ito S et al. |
TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. |
2014 |
Coron. Artery Dis. |
pmid:24448174
|
Czubowicz K and Strosznajder R |
Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate. |
2014 |
Mol. Neurobiol. |
pmid:24420784
|
Kerage D et al. |
Review: novel insights into the regulation of vascular tone by sphingosine 1-phosphate. |
2014 |
Placenta |
pmid:24411702
|
Abu El-Asrar AM et al. |
Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy. |
2014 |
Lipids Health Dis |
pmid:25496321
|
Zeng Y et al. |
Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. |
2014 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:24285115
|
Speak AO et al. |
Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1. |
2014 |
Blood |
pmid:24235134
|
Nagahashi M et al. |
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. |
2014 |
Adv Biol Regul |
pmid:24210073
|
Ratajczak MZ et al. |
The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cells. |
2014 |
Expert Opin. Ther. Targets |
pmid:24188167
|
Chawla S et al. |
Exogenous sphingosine 1-phosphate protects murine splenocytes against hypoxia-induced injury. |
2014 |
Lipids |
pmid:24190514
|
Rao PV |
Bioactive lysophospholipids: role in regulation of aqueous humor outflow and intraocular pressure in the context of pathobiology and therapy of glaucoma. |
2014 Mar-Apr |
J Ocul Pharmacol Ther |
pmid:24283588
|
Williams PA et al. |
Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). |
2015 |
PLoS ONE |
pmid:25875493
|
Wang Z et al. |
The Effect of Sphingosine 1-Phosphate/Sphingosine 1-Phosphate Receptor on Neutrophil Function and the Relevant Signaling Pathway. |
2015 |
Acta Haematol. |
pmid:25872153
|
Park ES et al. |
Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. |
2015 |
J. Biol. Chem. |
pmid:25716317
|
Rhee SH et al. |
Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall. |
2015 |
J Obstet Gynaecol |
pmid:25692679
|
Ji F et al. |
K6PC-5, a novel sphingosine kinase 1 (SphK1) activator, alleviates dexamethasone-induced damages to osteoblasts through activating SphK1-Akt signaling. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:25680461
|
Xiu L et al. |
Intracellular sphingosine 1-phosphate contributes to collagen expression of hepatic myofibroblasts in human liver fibrosis independent of its receptors. |
2015 |
Am. J. Pathol. |
pmid:25432063
|
Khavandgar Z and Murshed M |
Sphingolipid metabolism and its role in the skeletal tissues. |
2015 |
Cell. Mol. Life Sci. |
pmid:25424644
|
Prüfer N et al. |
The role of serum amyloid A and sphingosine-1-phosphate on high-density lipoprotein functionality. |
2015 |
Biol. Chem. |
pmid:25252751
|
Sorrentino R et al. |
B cell depletion increases sphingosine-1-phosphate-dependent airway inflammation in mice. |
2015 |
Am. J. Respir. Cell Mol. Biol. |
pmid:25250941
|
Abdel-Latif A et al. |
Lysophospholipids in coronary artery and chronic ischemic heart disease. |
2015 |
Curr. Opin. Lipidol. |
pmid:26270808
|
Iwabuchi K et al. |
Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. |
2015 |
Mediators Inflamm. |
pmid:26609196
|
Liu R et al. |
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. |
2015 |
J. Biol. Chem. |
pmid:26518876
|
Kassmer SH et al. |
Migration of germline progenitor cells is directed by sphingosine-1-phosphate signalling in a basal chordate. |
2015 |
Nat Commun |
pmid:26456232
|
Li C et al. |
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. |
2015 |
J Neuroinflammation |
pmid:25880547
|
Mori H et al. |
Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. |
2015 |
Am. J. Pathol. |
pmid:26272361
|
Camp SM et al. |
Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720. |
2015 |
Chem. Phys. Lipids |
pmid:26272033
|
Malik FA et al. |
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. |
2015 |
PLoS ONE |
pmid:26079370
|
Mooren OL et al. |
Role of N-WASP in Endothelial Monolayer Formation and Integrity. |
2015 |
J. Biol. Chem. |
pmid:26070569
|
Blaho VA et al. |
HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation. |
2015 |
Nature |
pmid:26053123
|
Tian H and Yu Z |
Resveratrol induces apoptosis of leukemia cell line K562 by modulation of sphingosine kinase-1 pathway. |
2015 |
Int J Clin Exp Pathol |
pmid:26045781
|