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Cell Death Dis |
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Bone |
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Mol Oncol |
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Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study. |
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Front Immunol |
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Cell Commun. Signal |
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Oncotarget |
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In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome. |
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The Utility of Biomarkers in Osteoporosis Management. |
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Mol Diagn Ther |
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Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling. |
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Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. |
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The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
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PLoS ONE |
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Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. |
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PLoS ONE |
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Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. |
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Diabetes |
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Fas/S1P crosstalk via NF-κB activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis. |
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β-Blockade Prevents Post-Ischemic Myocardial Decompensation Via βAR-Dependent Protective Sphingosine-1 Phosphate Signaling. |
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PLoS ONE |
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The effects of berberine on a murine model of multiple sclerosis and the SPHK1/S1P signaling pathway. |
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Sphingosine-1-Phosphate as the Lymphocyte's Ticket to Ride and Survive. |
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Dev. Cell |
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Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3β Phosphorylation. |
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Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. |
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High-Density Lipoprotein Regulation of Mitochondrial Function. |
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Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. |
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J. Am. Acad. Dermatol. |
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Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. |
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Nature |
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A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. |
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Dev. Cell |
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Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. |
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Expert Opin. Ther. Targets |
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Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
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Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
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Sphingosine 1-phosphate - A double edged sword in the brain. |
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Biochim. Biophys. Acta |
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A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. |
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J Pharm Biomed Anal |
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Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. |
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Glia |
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Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P) Agonists and Future Perspectives. |
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Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease. |
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Trends Mol Med |
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Modulation of sphingosine-1-phosphate in inflammatory bowel disease. |
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Autoimmun Rev |
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Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. |
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Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. |
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FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines. |
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Mediators Inflamm. |
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Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. |
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PLoS Biol. |
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Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. |
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Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. |
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Biochim. Biophys. Acta |
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HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. |
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Lipids Health Dis |
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Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. |
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Hum. Mol. Genet. |
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Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. |
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Diabetes |
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Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. |
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Am. J. Physiol., Cell Physiol. |
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The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. |
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Aging Cell |
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Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. |
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Cancer Invest. |
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Involvement of CETP (Cholesteryl Ester Transfer Protein) in the Shift of Sphingosine-1-Phosphate Among Lipoproteins and in the Modulation of its Functions. |
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Arterioscler. Thromb. Vasc. Biol. |
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