Sabbadini RA |
Targeting sphingosine-1-phosphate for cancer therapy. |
2006 |
Br. J. Cancer |
pmid:17024123
|
Rieken S et al. |
Lysophospholipids control integrin-dependent adhesion in splenic B cells through G(i) and G(12)/G(13) family G-proteins but not through G(q)/G(11). |
2006 |
J. Biol. Chem. |
pmid:17023430
|
Dragusin M et al. |
Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus. |
2006 |
FASEB J. |
pmid:16877527
|
Garg SK et al. |
Does sphingosine 1-phosphate play a protective role in the course of pulmonary tuberculosis? |
2006 |
Clin. Immunol. |
pmid:17049310
|
Kihara A |
[Multifunctional sphingolipid, sphingosine (long-chain base) 1-phosphate: physiological role, metabolism, and intracellular dynamics]. |
2006 |
Seikagaku |
pmid:16986722
|
Murph M et al. |
Of spiders and crabs: the emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer. |
2006 |
Clin. Cancer Res. |
pmid:17121877
|
Birgbauer E and Chun J |
New developments in the biological functions of lysophospholipids. |
2006 |
Cell. Mol. Life Sci. |
pmid:16988788
|
Ryu J et al. |
Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling. |
2006 |
EMBO J. |
pmid:17124500
|
Jin YX et al. |
Sphingosine kinase assay system with fluorescent detection in high performance liquid chromatography. |
2006 |
Arch. Pharm. Res. |
pmid:17146975
|
Taha TA et al. |
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death. |
2006 |
Biochim. Biophys. Acta |
pmid:17161984
|
Fisher KE et al. |
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. |
2006 |
Mol. Cancer |
pmid:17156449
|
Huwiler A and Pfeilschifter J |
Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. |
2006 |
Curr. Pharm. Des. |
pmid:17168766
|
Pan S et al. |
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. |
2006 |
Chem. Biol. |
pmid:17114004
|
Lee JF et al. |
Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity. |
2006 |
J. Biol. Chem. |
pmid:16891661
|
Zheng DM et al. |
Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide. |
2006 |
Hepatology |
pmid:17058266
|
Kabashima K et al. |
Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. |
2006 |
J. Exp. Med. |
pmid:17101733
|
Keller M et al. |
Sphingosine kinase functionally links elevated transmural pressure and increased reactive oxygen species formation in resistance arteries. |
2006 |
FASEB J. |
pmid:16476702
|
Wendler CC and Rivkees SA |
Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. |
2006 |
Dev. Biol. |
pmid:16434032
|
Wattenberg BW et al. |
The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function. |
2006 |
J. Lipid Res. |
pmid:16520486
|
Czyborra C et al. |
Indomethacin differentiates the renal effects of sphingosine-1-phosphate and sphingosylphosphorylcholine. |
2006 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:16521006
|
Sutherland CM et al. |
The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane. |
2006 |
J. Biol. Chem. |
pmid:16522638
|
Fieber CB et al. |
Modulation of total Akt kinase by increased expression of a single isoform: requirement of the sphingosine-1-phosphate receptor, Edg3/S1P3, for the VEGF-dependent expression of Akt3 in primary endothelial cells. |
2006 |
Exp. Cell Res. |
pmid:16527273
|
Berdyshev EV et al. |
De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells. |
2006 |
Cell. Signal. |
pmid:16529909
|
Malaplate-Armand C et al. |
Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway. |
2006 |
Neurobiol. Dis. |
pmid:16626961
|
Lin CI et al. |
Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism. |
2006 |
J. Cell. Biochem. |
pmid:16795034
|
Hiraga Y et al. |
Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16631609
|
French KJ et al. |
Antitumor activity of sphingosine kinase inhibitors. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16632640
|
Milstien S and Spiegel S |
Targeting sphingosine-1-phosphate: a novel avenue for cancer therapeutics. |
2006 |
Cancer Cell |
pmid:16530698
|
Visentin B et al. |
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. |
2006 |
Cancer Cell |
pmid:16530706
|
Scherer EQ et al. |
Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies? |
2006 |
Cardiovasc. Res. |
pmid:16533504
|
Rouach N et al. |
S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK. |
2006 |
Eur. J. Neurosci. |
pmid:16553609
|
Brizuela L et al. |
Sphingosine 1-phosphate: a novel stimulator of aldosterone secretion. |
2006 |
J. Lipid Res. |
pmid:16554657
|
Chatterjee S et al. |
The role of the phospholipid sphingomyelin in heart disease. |
2006 |
Curr Opin Investig Drugs |
pmid:16555682
|
Zeidan YH et al. |
Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production. |
2006 |
J. Biol. Chem. |
pmid:16803890
|
Dindo D et al. |
Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells. |
2006 |
Mol. Cancer Ther. |
pmid:16818511
|
Durand CA et al. |
The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes. |
2006 |
Eur. J. Immunol. |
pmid:16821235
|
Giussani P et al. |
Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. |
2006 |
Mol. Cell. Biol. |
pmid:16782891
|
Sanna MG et al. |
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. |
2006 |
Nat. Chem. Biol. |
pmid:16829954
|
Veracini L et al. |
Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles. |
2006 |
J. Cell. Sci. |
pmid:16787943
|
Laychock SG et al. |
Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells. |
2006 |
Endocrinology |
pmid:16794003
|
Oz-Arslan D et al. |
IL-6 and IL-8 release is mediated via multiple signaling pathways after stimulating dendritic cells with lysophospholipids. |
2006 |
J. Leukoc. Biol. |
pmid:16769764
|
Garbers DL et al. |
Membrane guanylyl cyclase receptors: an update. |
2006 |
Trends Endocrinol. Metab. |
pmid:16815030
|
Yan L et al. |
2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16621543
|
Venkataraman K et al. |
Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient. |
2006 |
Biochem. J. |
pmid:16623665
|
Weigert A et al. |
Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. |
2006 |
Blood |
pmid:16690965
|
Kim MK et al. |
Sphingosine-1-phosphate stimulates rat primary chondrocyte proliferation. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16674917
|
Xu SZ et al. |
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. |
2006 |
Circ. Res. |
pmid:16675717
|
Hemmings DG et al. |
Sphingosine-1-phosphate acts via rho-associated kinase and nitric oxide to regulate human placental vascular tone. |
2006 |
Biol. Reprod. |
pmid:16162874
|
Yamashita H et al. |
Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation. |
2006 |
J. Surg. Res. |
pmid:16183075
|
Sparkman L et al. |
Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. |
2006 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:16183668
|
Ozbay T et al. |
Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1. |
2006 |
Endocrinology |
pmid:16306078
|
Kobayashi N et al. |
Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner. |
2006 |
J. Lipid Res. |
pmid:16371645
|
Kono M et al. |
Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. |
2006 |
J. Biol. Chem. |
pmid:16380386
|
von Otte S et al. |
Follicular fluid high density lipoprotein-associated sphingosine 1-phosphate is a novel mediator of ovarian angiogenesis. |
2006 |
J. Biol. Chem. |
pmid:16365044
|
Alewijnse AE and Michel MC |
Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind? |
2006 |
Br. J. Pharmacol. |
pmid:16402045
|
Mathieson FA and Nixon GF |
Sphingolipids differentially regulate mitogen-activated protein kinases and intracellular Ca2+ in vascular smooth muscle: effects on CREB activation. |
2006 |
Br. J. Pharmacol. |
pmid:16402047
|
Chantrain CF et al. |
Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases. |
2006 |
Eur. J. Cancer |
pmid:16406506
|
Olivera A et al. |
IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses. |
2006 |
J. Biol. Chem. |
pmid:16316995
|
Ramasamy R et al. |
Sphingosine-1-phosphate: waging a battle in the diabetic blood vessel. |
2006 |
Circ. Res. |
pmid:17008596
|
Park KS et al. |
Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins. |
2006 |
Mol. Pharmacol. |
pmid:16368894
|
Dahm F et al. |
Distribution and dynamic changes of sphingolipids in blood in response to platelet activation. |
2006 |
J. Thromb. Haemost. |
pmid:17010150
|
Gardell SE et al. |
Emerging medicinal roles for lysophospholipid signaling. |
2006 |
Trends Mol Med |
pmid:16406843
|
Kim MY et al. |
Sphingosine-1-phosphate activates BKCa channels independently of G protein-coupled receptor in human endothelial cells. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16267108
|
di Villa Bianca Rd et al. |
Sphingosine 1-phosphate induces endothelial nitric-oxide synthase activation through phosphorylation in human corpus cavernosum. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16234413
|
Bu S et al. |
Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. |
2006 |
FASEB J. |
pmid:16278291
|
Inniss K and Moore H |
Mediation of apoptosis and proliferation of human embryonic stem cells by sphingosine-1-phosphate. |
2006 |
Stem Cells Dev. |
pmid:17253942
|
Matsuyuki H et al. |
Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P. |
2006 |
Cell. Mol. Immunol. |
pmid:17257496
|
Rahaman M et al. |
Neutrophil sphingosine 1-phosphate and lysophosphatidic acid receptors in pneumonia. |
2006 |
Am. J. Respir. Cell Mol. Biol. |
pmid:16224106
|
Kang JS et al. |
Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways. |
2006 |
Mol. Pharmacol. |
pmid:16354764
|
Schmidt H et al. |
LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:17085324
|
Tardieu D et al. |
Effects of fumonisins on liver and kidney sphinganine and the sphinganine to sphingosine ratio during chronic exposure in ducks. |
2006 |
Chem. Biol. Interact. |
pmid:16412405
|
Eigenbrod S et al. |
Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells. |
2006 |
Immunol. Invest. |
pmid:16698674
|
Massberg S and von Andrian UH |
Fingolimod and sphingosine-1-phosphate--modifiers of lymphocyte migration. |
2006 |
N. Engl. J. Med. |
pmid:16971715
|
Jun DJ et al. |
Sphingosine-1-phosphate modulates both lipolysis and leptin production in differentiated rat white adipocytes. |
2006 |
Endocrinology |
pmid:16973728
|
Natarajan J et al. |
Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line. |
2006 |
BMC Bioinformatics |
pmid:16901352
|
Young N and Van Brocklyn JR |
Signal transduction of sphingosine-1-phosphate G protein-coupled receptors. |
2006 |
ScientificWorldJournal |
pmid:16906327
|
Hait NC et al. |
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases. |
2006 |
Biochim. Biophys. Acta |
pmid:16996023
|
Minshall RD and Malik AB |
Transport across the endothelium: regulation of endothelial permeability. |
2006 |
Handb Exp Pharmacol |
pmid:16999218
|
Smicun Y et al. |
S1P regulation of ovarian carcinoma invasiveness. |
2006 |
Gynecol. Oncol. |
pmid:16956652
|
Squecco R et al. |
Sphingosine 1-phosphate induces myoblast differentiation through Cx43 protein expression: a role for a gap junction-dependent and -independent function. |
2006 |
Mol. Biol. Cell |
pmid:16957055
|
Donati C and Bruni P |
Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. |
2006 |
Biochim. Biophys. Acta |
pmid:16890187
|
Thompson B et al. |
Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846783
|
Long JS et al. |
The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16846788
|
Nagata Y et al. |
Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling. |
2006 |
J. Cell Biol. |
pmid:16847102
|
Xu R et al. |
Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. |
2006 |
FASEB J. |
pmid:16940153
|
Schultz C |
Lipid-induced phenotypes. |
2006 |
Nat. Chem. Biol. |
pmid:16850012
|
Brinkmann V and Baumruker T |
Pulmonary and vascular pharmacology of sphingosine 1-phosphate. |
2006 |
Curr Opin Pharmacol |
pmid:16563863
|
Hemmings DG |
Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine. |
2006 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:16570136
|
Choueiri TK et al. |
Phenoxodiol: isoflavone analog with antineoplastic activity. |
2006 |
Curr Oncol Rep |
pmid:16507219
|
Naetzker S et al. |
Activation of p38 mitogen-activated protein kinase and partial reactivation of the cell cycle by cis-4-methylsphingosine direct postmitotic neurons towards apoptosis. |
2006 |
Genes Cells |
pmid:16483315
|
Jurisicova A et al. |
Molecular requirements for doxorubicin-mediated death in murine oocytes. |
2006 |
Cell Death Differ. |
pmid:16439991
|
Bassi R et al. |
Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. |
2006 |
Glia |
pmid:16470810
|
Yatomi Y |
Sphingosine 1-phosphate in vascular biology: possible therapeutic strategies to control vascular diseases. |
2006 |
Curr. Pharm. Des. |
pmid:16472149
|
Kurobe H et al. |
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. |
2006 |
Immunity |
pmid:16473829
|
Kitano M et al. |
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression. |
2006 |
Arthritis Rheum. |
pmid:16508938
|
Hsieh HL et al. |
Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells. |
2006 |
J. Cell. Physiol. |
pmid:16508949
|
Becciolini L et al. |
Sphingosine 1-phosphate inhibits cell migration in C2C12 myoblasts. |
2006 |
Biochim. Biophys. Acta |
pmid:16510307
|
Song HJ et al. |
Sphingosine 1-phosphate-induced signal transduction in cat esophagus smooth muscle cells. |
2006 |
Mol. Cells |
pmid:16511346
|
Takai S et al. |
Phosphatidylinositol 3-kinase/Akt plays a role in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. |
2006 |
J. Cell. Biochem. |
pmid:16514645
|
Idzko M et al. |
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. |
2006 |
J. Clin. Invest. |
pmid:17080194
|