Al Alam N and Kreydiyyeh SI |
FTY720P inhibits hepatic Na(+)-K(+) ATPase via S1PR2 and PGE2. |
2016 |
Biochem. Cell Biol. |
pmid:27501354
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Fu P et al. |
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. |
2016 |
J. Biol. Chem. |
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Terashita T et al. |
Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. |
2016 |
Respir. Res. |
pmid:27829417
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Dong T et al. |
Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury. |
2016 |
J Neuroinflammation |
pmid:27561600
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Nojima H et al. |
Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. |
2016 |
PLoS ONE |
pmid:27551720
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Harris CM et al. |
Sphingosine-1-Phosphate (S1P) Lyase Inhibition Causes Increased Cardiac S1P Levels and Bradycardia in Rats. |
2016 |
J. Pharmacol. Exp. Ther. |
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Gstalder C et al. |
FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model. |
2016 |
Mol. Cancer Ther. |
pmid:27507852
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Hashimoto Y et al. |
Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. |
2016 |
Cell Biol. Int. |
pmid:27486054
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Viswanathan P et al. |
Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. |
2016 |
Biochem. Biophys. Res. Commun. |
pmid:27473658
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Moruno Manchon JF et al. |
SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. |
2016 |
Autophagy |
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Nagahashi M et al. |
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. |
2016 |
J. Lipid Res. |
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Rumzhum NN et al. |
Effect of Sphingosine 1-Phosphate on Cyclo-Oxygenase-2 Expression, Prostaglandin E2 Secretion, and β2-Adrenergic Receptor Desensitization. |
2016 |
Am. J. Respir. Cell Mol. Biol. |
pmid:26098693
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Marfia G et al. |
The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling. |
2016 |
Stem Cells Dev. |
pmid:27217090
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Versmissen J et al. |
Familial hypercholesterolaemia: cholesterol efflux and coronary disease. |
2016 |
Eur. J. Clin. Invest. |
pmid:27208892
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Sauvé M et al. |
Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes. |
2016 |
Diabetes |
pmid:27207546
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Zhang XE et al. |
Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. |
2016 |
PLoS ONE |
pmid:27187066
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Ohtoyo M et al. |
Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate. |
2016 |
Cell Chem Biol |
pmid:27185637
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Barnawi J et al. |
Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. |
2016 |
COPD |
pmid:27144721
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Jin L et al. |
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined. |
2016 |
World J Surg Oncol |
pmid:27129720
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Sanchez T |
Sphingosine-1-Phosphate Signaling in Endothelial Disorders. |
2016 |
Curr Atheroscler Rep |
pmid:27115142
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Tang X et al. |
Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate. |
2016 |
J. Lipid Res. |
pmid:26884614
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Yang Y et al. |
Sphingosine kinase inhibition ameliorates chronic hypoperfusion-induced white matter lesions. |
2016 |
Neurochem. Int. |
pmid:26921668
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Park K et al. |
ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex. |
2016 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:26903652
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Bien-Möller S et al. |
Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. |
2016 |
Oncotarget |
pmid:26887055
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Uranbileg B et al. |
Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. |
2016 |
PLoS ONE |
pmid:26886371
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Chumanevich A et al. |
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. |
2016 |
Mediators Inflamm. |
pmid:26884643
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Ko P et al. |
Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. |
2016 |
Sci Rep |
pmid:26877098
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Luo B et al. |
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
2016 |
Immunity |
pmid:26872696
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Gomez-Muñoz A et al. |
Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate. |
2016 |
Prog. Lipid Res. |
pmid:26703189
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Ottenlinger F et al. |
Fingolimod targeting protein phosphatase 2A differently affects IL-33 induced IL-2 and IFN-γ production in CD8(+) lymphocytes. |
2016 |
Eur. J. Immunol. |
pmid:26683421
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Fan A et al. |
Liver X receptor-α and miR-130a-3p regulate expression of sphingosine 1-phosphate receptor 2 in human umbilical vein endothelial cells. |
2016 |
Am. J. Physiol., Cell Physiol. |
pmid:26669941
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Petrache I and Berdyshev EV |
Ceramide Signaling and Metabolism in Pathophysiological States of the Lung. |
2016 |
Annu. Rev. Physiol. |
pmid:26667073
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Delgado A and MartÃnez-Cartro M |
Therapeutic Potential of the Modulation of Sphingosine-1-Phosphate Receptors. |
2016 |
Curr. Med. Chem. |
pmid:26639095
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Yamamoto S et al. |
A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). |
2016 |
Mol. Biol. Cell |
pmid:26631556
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Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. |
2016 |
J. Lipid Res. |
pmid:26621917
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Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. |
2016 |
Biochim. Biophys. Acta |
pmid:26615875
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Gao D et al. |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26859520
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Nigro E et al. |
Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation. |
2016 |
Pharmacol. Res. |
pmid:26462929
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Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. |
2016 |
Brain Behav. Immun. |
pmid:26456693
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Arish M et al. |
Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. |
2016 |
Drug Discov. Today |
pmid:26456576
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Melnik BC |
Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research. |
2016 |
Acta Derm. Venereol. |
pmid:26304030
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Hsia K et al. |
Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. |
2017 |
Acta Biomater |
pmid:28110073
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O'Sullivan S and Dev KK |
Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. |
2017 |
Neuropharmacology |
pmid:27825807
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Swendeman SL et al. |
An engineered S1P chaperone attenuates hypertension and ischemic injury. |
2017 |
Sci Signal |
pmid:28811382
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Syed SN et al. |
S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1 or Lipocalin-2. |
2017 |
Mediators Inflamm. |
pmid:28804221
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Janecke AR et al. |
Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. |
2017 |
Hum. Mutat. |
pmid:28181337
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Moritz E et al. |
Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. |
2017 |
Clin. Chim. Acta |
pmid:28159438
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Nakajima M et al. |
The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. |
2017 |
Tumour Biol. |
pmid:28381169
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Garbowska M et al. |
Sphingolipids metabolism in the salivary glands of rats with obesity and streptozotocin induced diabetes. |
2017 |
J. Cell. Physiol. |
pmid:28369933
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Wang Y et al. |
The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice. |
2017 |
Hepatology |
pmid:28120434
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