| MeSH term | MeSH ID | Detail |
|---|---|---|
| Peripheral Arterial Disease | D058729 | 7 associated lipids |
Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kimizuka K et al. | Sphingosine 1-phosphate (S1P) induces S1P2 receptor-dependent tonic contraction in murine iliac lymph vessels. | 2013 | Microcirculation | pmid:22913344 |
| Donati C et al. | New insights into the role of sphingosine 1-phosphate and lysophosphatidic acid in the regulation of skeletal muscle cell biology. | 2013 | Biochim. Biophys. Acta | pmid:22877992 |
| Taub DD et al. | Distinct energy requirements for human memory CD4 T-cell homeostatic functions. | 2013 | FASEB J. | pmid:22972918 |
| Gaveglio VL et al. | Phosphatidic acid metabolism in rat liver cell nuclei. | 2013 | FEBS Lett. | pmid:23439070 |
| Kurek K et al. | [The role of sphingolipids in selected cardiovascular diseases]. | 2013 | Postepy Hig Med Dosw (Online) | pmid:24088546 |
| Kowalski GM et al. | Plasma sphingosine-1-phosphate is elevated in obesity. | 2013 | PLoS ONE | pmid:24039766 |
| Ota K et al. | TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. | 2013 | Endocrinology | pmid:23861379 |
| Ohotski J et al. | Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. | 2013 | Int. J. Cancer | pmid:22733311 |
| Chan H and Pitson SM | Post-translational regulation of sphingosine kinases. | 2013 | Biochim. Biophys. Acta | pmid:22801036 |
| Orr Gandy KA and Obeid LM | Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors. | 2013 | Biochim. Biophys. Acta | pmid:22801037 |
| Saba JD and de la Garza-Rodea AS | S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase. | 2013 | Biochim. Biophys. Acta | pmid:22750505 |
| Selhub J et al. | Dietary vitamin B6 intake modulates colonic inflammation in the IL10-/- model of inflammatory bowel disease. | 2013 | J. Nutr. Biochem. | pmid:24183308 |
| Watson DG et al. | The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. | 2013 | Cell. Signal. | pmid:23314175 |
| Ohkawa R et al. | [Sphingolipids, possible biomarkers for atherosclerotic disorders]. | 2013 | Rinsho Byori | pmid:24369591 |
| Yu H et al. | Insulin protects apoptotic cardiomyocytes from hypoxia/reoxygenation injury through the sphingosine kinase/sphingosine 1-phosphate axis. | 2013 | PLoS ONE | pmid:24349009 |
| Walls SM et al. | Identification of sphingolipid metabolites that induce obesity via misregulation of appetite, caloric intake and fat storage in Drosophila. | 2013 | PLoS Genet. | pmid:24339790 |
| Brewer JW | Phospholipids: "greasing the wheels" of humoral immunity. | 2013 | Biochim. Biophys. Acta | pmid:23051607 |
| Schwalm S et al. | Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. | 2013 | Biochim. Biophys. Acta | pmid:22889995 |
| Tran-Dinh A et al. | HDL and endothelial protection. | 2013 | Br. J. Pharmacol. | pmid:23488589 |
| Mudd JC et al. | Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes. | 2013 | Blood | pmid:23422746 |
| Camacho L et al. | Acid ceramidase as a therapeutic target in metastatic prostate cancer. | 2013 | J. Lipid Res. | pmid:23423838 |
| Kawahara S et al. | Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells. | 2013 | Anticancer Drugs | pmid:23426175 |
| Yang L et al. | Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis. | 2013 | J. Hepatol. | pmid:23466305 |
| Reichardt P et al. | A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes. | 2013 | EMBO J. | pmid:23443048 |
| Natarajan V et al. | Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23449739 |
| Kusch A et al. | Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury. | 2013 | Acta Physiol (Oxf) | pmid:23432924 |
| Hardin C et al. | Glassy dynamics, cell mechanics, and endothelial permeability. | 2013 | J Phys Chem B | pmid:23638866 |
| Xiang SY et al. | PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart. | 2013 | Sci Signal | pmid:24345679 |
| Kendig DM et al. | Sphingosine-1-phosphate induced contraction of bladder smooth muscle. | 2013 | Eur. J. Pharmacol. | pmid:24120660 |
| Goyal P et al. | Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways. | 2013 | Mol. Hum. Reprod. | pmid:23538947 |
| Allende ML et al. | Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis. | 2013 | J. Biol. Chem. | pmid:23637227 |
| Schaper K et al. | Sphingosine-1-phosphate exhibits anti-proliferative and anti-inflammatory effects in mouse models of psoriasis. | 2013 | J. Dermatol. Sci. | pmid:23643308 |
| Böhm A et al. | Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells. | 2013 | Cardiovasc. Res. | pmid:23658376 |
| Kurano M et al. | Liver involvement in sphingosine 1-phosphate dynamism revealed by adenoviral hepatic overexpression of apolipoprotein M. | 2013 | Atherosclerosis | pmid:23664237 |
| Stradner MH et al. | Sphingosine 1-phosphate counteracts the effects of interleukin-1β in human chondrocytes. | 2013 | Arthritis Rheum. | pmid:23666803 |
| Usatyuk PV et al. | Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction. | 2013 | PLoS ONE | pmid:23667561 |
| Starzyńska T et al. | An intensified systemic trafficking of bone marrow-derived stem/progenitor cells in patients with pancreatic cancer. | 2013 | J. Cell. Mol. Med. | pmid:23672538 |
| Osawa Y et al. | Liver acid sphingomyelinase inhibits growth of metastatic colon cancer. | 2013 | J. Clin. Invest. | pmid:23298833 |
| Xu Y et al. | Low sphingosine-1-phosphate impairs lung dendritic cells in cystic fibrosis. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23239501 |
| Evindar G et al. | Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23245510 |
| Billich A et al. | Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors. | 2013 | Anal. Biochem. | pmid:23246729 |
| Dusaban SS et al. | Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23401561 |
| Gandy KA et al. | Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins. | 2013 | Biochem. J. | pmid:23106337 |
| Pantoja M et al. | Genetic elevation of sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila. | 2013 | Development | pmid:23154413 |
| Takahashi K et al. | Novel therapy for liver regeneration by increasing the number of platelets. | 2013 | Surg. Today | pmid:23180116 |
| Lidington D et al. | Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness. | 2013 | Cardiovasc. Res. | pmid:23180720 |
| Nagahashi M et al. | Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network. | 2013 | FASEB J. | pmid:23180825 |
| Huang J et al. | Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway. | 2013 | Mol. Cell. Endocrinol. | pmid:23127801 |
| Carr JM et al. | Sphingosine kinase 1 in viral infections. | 2013 | Rev. Med. Virol. | pmid:22639116 |
| Lotinun S et al. | Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation. | 2013 | J. Clin. Invest. | pmid:23321671 |
| Selvam SP and Ogretmen B | Sphingosine kinase/sphingosine 1-phosphate signaling in cancer therapeutics and drug resistance. | 2013 | Handb Exp Pharmacol | pmid:23563649 |
| Pyne S and Pyne NJ | New perspectives on the role of sphingosine 1-phosphate in cancer. | 2013 | Handb Exp Pharmacol | pmid:23563651 |
| Jiang XC and Liu J | Sphingolipid metabolism and atherosclerosis. | 2013 | Handb Exp Pharmacol | pmid:23563655 |
| Levkau B | Cardiovascular effects of sphingosine-1-phosphate (S1P). | 2013 | Handb Exp Pharmacol | pmid:23563656 |
| Abbasi T and Garcia JG | Sphingolipids in lung endothelial biology and regulation of vascular integrity. | 2013 | Handb Exp Pharmacol | pmid:23563658 |
| Gandy KA and Obeid LM | Regulation of the sphingosine kinase/sphingosine 1-phosphate pathway. | 2013 | Handb Exp Pharmacol | pmid:23563662 |
| Bruni P and Donati C | Role of sphingosine 1-phosphate in skeletal muscle cell biology. | 2013 | Handb Exp Pharmacol | pmid:23563671 |
| Vessey DA et al. | FTY720 postconditions isolated perfused heart by a mechanism independent of sphingosine kinase 2 and different from S1P or ischemic postconditioning. | 2013 | Med Sci Monit Basic Res | pmid:23567658 |
| Wallington-Beddoe CT et al. | Oncogenic properties of sphingosine kinases in haematological malignancies. | 2013 | Br. J. Haematol. | pmid:23521541 |
| Bendall LJ and Basnett J | Role of sphingosine 1-phosphate in trafficking and mobilization of hematopoietic stem cells. | 2013 | Curr. Opin. Hematol. | pmid:23507960 |
| Erkhembaatar LO et al. | Increased expression of sphingosine kinase in the amnion during labor. | 2013 | Placenta | pmid:23462226 |
| Kikuta J et al. | Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23569273 |
| Pyne NJ et al. | Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis. | 2013 | Biochim. Biophys. Acta | pmid:22801038 |
| Huang LS et al. | Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis. | 2013 | FASEB J. | pmid:23315259 |
| Lukowski ZL et al. | Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model. | 2013 | J. Glaucoma | pmid:21946553 |
| Rokka J et al. | 19F/18F exchange synthesis for a novel [18F]S1P3-radiopharmaceutical. | 2013 | J Labelled Comp Radiopharm | pmid:24285478 |
| Kajimoto T et al. | Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes. | 2013 | Nat Commun | pmid:24231649 |
| Ito S et al. | Increased plasma sphingosine-1-phosphate in obese individuals and its capacity to increase the expression of plasminogen activator inhibitor-1 in adipocytes. | 2013 | Coron. Artery Dis. | pmid:24212262 |
| Lim SH et al. | Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting. | 2013 | Integr Biol (Camb) | pmid:24190477 |
| Lamichhane A et al. | Nutritional components regulate the gut immune system and its association with intestinal immune disease development. | 2013 | J. Gastroenterol. Hepatol. | pmid:24251698 |
| Morozov VI et al. | Sphingosine-1-phosphate: distribution, metabolism and role in the regulation of cellular functions. | 2013 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:23534286 |
| Ratajczak MZ et al. | An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1-phosphate. | 2013 Jul-Aug | Prostaglandins Other Lipid Mediat. | pmid:22981511 |
| Lee H et al. | 4-Deoxypyridoxine improves the viability of isolated pancreatic islets ex vivo. | 2013 May-Jun | Islets | pmid:23756681 |
| Egom EE et al. | Activation of sphingosine-1-phosphate signalling as a potential underlying mechanism of the pleiotropic effects of statin therapy. | 2013 May-Jun | Crit Rev Clin Lab Sci | pmid:23885725 |
| Che W et al. | Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1. | 2014 | Am. J. Respir. Cell Mol. Biol. | pmid:24032470 |
| Chang N et al. | Sphingosine 1-phosphate receptors negatively regulate collagen type I/III expression in human bone marrow-derived mesenchymal stem cell. | 2014 | J. Cell. Biochem. | pmid:24038457 |
| Moxon JV et al. | Comparison of the serum lipidome in patients with abdominal aortic aneurysm and peripheral artery disease. | 2014 | Circ Cardiovasc Genet | pmid:24448739 |
| Gorlino CV et al. | Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes. | 2014 | J. Immunol. | pmid:25015824 |
| Langeslag M et al. | Sphingosine 1-phosphate to p38 signaling via S1P1 receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons. | 2014 | Mol Pain | pmid:25431213 |
| Callihan P et al. | Convergent regulation of neuronal differentiation and Erk and Akt kinases in human neural progenitor cells by lysophosphatidic acid, sphingosine 1-phosphate, and LIF: specific roles for the LPA1 receptor. | 2014 | ASN Neuro | pmid:25424429 |
| Huang K et al. | AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose. | 2014 | Cell. Signal. | pmid:24342046 |
| Slattum G et al. | Autophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1P. | 2014 | Curr. Biol. | pmid:24361067 |
| Miller DS | Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule. | 2014 | J. Pharmacol. Exp. Ther. | pmid:24385389 |
| Dai L et al. | Sphingosine 1-phosphate: a potential molecular target for ovarian cancer therapy? | 2014 | Cancer Invest. | pmid:24499107 |
| Park K et al. | The dietary ingredient, genistein, stimulates cathelicidin antimicrobial peptide expression through a novel S1P-dependent mechanism. | 2014 | J. Nutr. Biochem. | pmid:24768661 |
| Iino J et al. | Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells. | 2014 | Lipids Health Dis | pmid:25253303 |
| Xiong Y et al. | Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development. | 2014 | J. Clin. Invest. | pmid:25250575 |
| Shayegi N et al. | CXCR4 blockade and sphingosine-1-phosphate activation facilitate engraftment of haematopoietic stem and progenitor cells in a non-myeloablative transplant model. | 2014 | Br. J. Haematol. | pmid:24180707 |
| Kim ES et al. | Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. | 2014 | Oncogene | pmid:23955082 |
| Moon MH et al. | Sphingosine-1-phosphate inhibits the adipogenic differentiation of 3T3-L1 preadipocytes. | 2014 | Int. J. Mol. Med. | pmid:25050633 |
| Wakashima T et al. | Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation. | 2014 | J. Biol. Chem. | pmid:25049234 |
| Marfia G et al. | Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells. | 2014 | Glia | pmid:25042636 |
| Schwalm S et al. | Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:23789924 |
| Tsai YC et al. | Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. | 2014 | Reprod Sci | pmid:23793475 |
| Ceglarek U et al. | Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. | 2014 | Clin. Chim. Acta | pmid:24768784 |
| Brizuela L et al. | Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells. | 2014 | Mol Oncol | pmid:24768038 |
| Gil-Ortega M et al. | Ex vivo microperfusion system of the adipose organ: a new approach to studying the mobilization of adipose cell populations. | 2014 | Int J Obes (Lond) | pmid:24357852 |
| Maeda Y et al. | S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1. | 2014 | Int. Immunol. | pmid:24343820 |
| Guo L et al. | Roles of sphingosine-1-phosphate in reproduction. | 2014 | Reprod Sci | pmid:24336672 |
| Shen Z et al. | Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α). | 2014 | Cell Stress Chaperones | pmid:24293320 |