Jiang LI et al. |
Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway. |
2013 |
Mol. Pharmacol. |
pmid:23229509
|
Kager LM et al. |
Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis). |
2013 |
J. Thromb. Haemost. |
pmid:23216621
|
Nagahashi M et al. |
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network. |
2013 |
FASEB J. |
pmid:23180825
|
Lidington D et al. |
Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness. |
2013 |
Cardiovasc. Res. |
pmid:23180720
|
Takahashi K et al. |
Novel therapy for liver regeneration by increasing the number of platelets. |
2013 |
Surg. Today |
pmid:23180116
|
Kurek K et al. |
[Role of sphingolipids in digestive system]. |
2012 |
Postepy Hig Med Dosw (Online) |
pmid:23175343
|
Cuvillier O |
[Sphingosine 1-phosphate receptors: from biology to physiopathology]. |
2012 |
Med Sci (Paris) |
pmid:23171898
|
Cartwright TA et al. |
Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers. |
2013 |
J. Cereb. Blood Flow Metab. |
pmid:23168528
|
Hla T et al. |
S1P and the birth of platelets. |
2012 |
J. Exp. Med. |
pmid:23166370
|
Pantoja M et al. |
Genetic elevation of sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila. |
2013 |
Development |
pmid:23154413
|
Qiao Y et al. |
Sphingosine 1-phosphate elicits proinflammatory responses in ARPE-19 cells. |
2012 |
Invest. Ophthalmol. Vis. Sci. |
pmid:23150617
|
Zhang L et al. |
A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis. |
2012 |
J. Exp. Med. |
pmid:23148237
|
Japtok L et al. |
Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtype. |
2012 |
PLoS ONE |
pmid:23145172
|
Tar L and Vécsei L |
[Fingolimod therapy in multiple sclerosis--the issue of the pathomechanism]. |
2012 |
Ideggyogy Sz |
pmid:23136726
|
Wilkerson BA et al. |
Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: high density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1. |
2012 |
J. Biol. Chem. |
pmid:23135269
|
Huang J et al. |
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway. |
2013 |
Mol. Cell. Endocrinol. |
pmid:23127801
|
Gandy KA et al. |
Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins. |
2013 |
Biochem. J. |
pmid:23106337
|
Mendoza A et al. |
The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. |
2012 |
Cell Rep |
pmid:23103166
|
Ma Y et al. |
Sphingosine-1-phosphate (S1P) mediates darkness-induced stomatal closure through raising cytosol pH and hydrogen peroxide (Hâ‚‚Oâ‚‚) levels in guard cells in Vicia faba. |
2012 |
Sci China Life Sci |
pmid:23090064
|
Fernández-Pisonero I et al. |
Lipopolysaccharide and sphingosine-1-phosphate cooperate to induce inflammatory molecules and leukocyte adhesion in endothelial cells. |
2012 |
J. Immunol. |
pmid:23089395
|
Véret J et al. |
Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival. |
2013 |
Biochim. Biophys. Acta |
pmid:23085009
|
Sorci-Thomas MG and Thomas MJ |
High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. |
2012 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:23077142
|
Di Menna L et al. |
Fingolimod protects cultured cortical neurons against excitotoxic death. |
2013 |
Pharmacol. Res. |
pmid:23073075
|
Brewer JW |
Phospholipids: "greasing the wheels" of humoral immunity. |
2013 |
Biochim. Biophys. Acta |
pmid:23051607
|
Kawashima T et al. |
Contrary effects of sphingosine-1-phosphate on expression of α-smooth muscle actin in transforming growth factor β1-stimulated lung fibroblasts. |
2012 |
Eur. J. Pharmacol. |
pmid:23041148
|
Taniguchi M et al. |
Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway. |
2012 |
J. Biol. Chem. |
pmid:23035115
|
Park TS and Goldberg IJ |
Sphingolipids, lipotoxic cardiomyopathy, and cardiac failure. |
2012 |
Heart Fail Clin |
pmid:22999245
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes. |
2012 |
Int. J. Mol. Med. |
pmid:22992945
|
Patel SA et al. |
Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity. |
2012 |
Endocrinology |
pmid:22989629
|
Xiang SY et al. |
Lysophospholipid receptor activation of RhoA and lipid signaling pathways. |
2013 |
Biochim. Biophys. Acta |
pmid:22986288
|
Aoyagi T et al. |
The role of sphingosine-1-phosphate in breast cancer tumor-induced lymphangiogenesis. |
2012 |
Lymphat Res Biol |
pmid:22984905
|
Ratajczak MZ et al. |
An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1-phosphate. |
2013 Jul-Aug |
Prostaglandins Other Lipid Mediat. |
pmid:22981511
|
Taub DD et al. |
Distinct energy requirements for human memory CD4 T-cell homeostatic functions. |
2013 |
FASEB J. |
pmid:22972918
|
Knapp M et al. |
Myocardial infarction differentially alters sphingolipid levels in plasma, erythrocytes and platelets of the rat. |
2012 |
Basic Res. Cardiol. |
pmid:22961594
|
Richerioux N et al. |
Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. |
2012 |
PLoS ONE |
pmid:22952878
|
Cannon RE et al. |
Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22949658
|
Snider AJ et al. |
Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. |
2012 |
Prostaglandins Other Lipid Mediat. |
pmid:22940715
|
Jin YX et al. |
A strategy for enrichment of the bioactive sphingoid base-1-phosphates produced by Hypericum perforatum L. in a balloon type airlift reactor. |
2012 |
Bioresour. Technol. |
pmid:22940331
|
Price MM et al. |
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma. |
2013 |
J. Allergy Clin. Immunol. |
pmid:22939756
|
Wang ZY et al. |
[Effect of sphingosine 1-phosphate/sphingosine 1-phosphate receptor signal pathway on function of neutrophils]. |
2012 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:22931670
|
Hisano Y et al. |
The functional roles of S1P in immunity. |
2012 |
J. Biochem. |
pmid:22923732
|
He S et al. |
Self-amplification mechanisms of mast cell activation: a new look in allergy. |
2012 |
Curr. Mol. Med. |
pmid:22920722
|
Kimizuka K et al. |
Sphingosine 1-phosphate (S1P) induces S1P2 receptor-dependent tonic contraction in murine iliac lymph vessels. |
2013 |
Microcirculation |
pmid:22913344
|
Ihlefeld K et al. |
Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts. |
2012 |
Biochem. J. |
pmid:22908849
|
Egom EE |
A therapeutic approach to hyperglycaemia in the setting of acute myocardial infarction: spotlight on glucagon-like peptide 1. |
2012 |
Ther Adv Cardiovasc Dis |
pmid:22902834
|
Schmitz EI et al. |
Sphingosine 1-phosphate protects primary human keratinocytes from apoptosis via nitric oxide formation through the receptor subtype S1P₃. |
2012 |
Mol. Cell. Biochem. |
pmid:22899173
|
Masuko K et al. |
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. |
2012 |
Int J Rheum Dis |
pmid:22898216
|
Schwalm S et al. |
Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. |
2013 |
Biochim. Biophys. Acta |
pmid:22889995
|
Asghar MY et al. |
Sphingosine 1-phosphate and human ether-a'-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells. |
2012 |
Endocr. Relat. Cancer |
pmid:22889737
|
Miller E et al. |
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. |
2012 |
Chem. Biol. |
pmid:22884261
|
Kim BJ et al. |
Plasma sphingosine 1-phosphate levels and the risk of vertebral fracture in postmenopausal women. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22879631
|
Donati C et al. |
New insights into the role of sphingosine 1-phosphate and lysophosphatidic acid in the regulation of skeletal muscle cell biology. |
2013 |
Biochim. Biophys. Acta |
pmid:22877992
|
Curry FE et al. |
Erythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels. |
2012 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:22865384
|
Yu FX et al. |
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. |
2012 |
Cell |
pmid:22863277
|
Liu Q et al. |
Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. |
2012 |
PLoS ONE |
pmid:22848628
|
Pitman MR et al. |
Molecular targets of FTY720 (fingolimod). |
2012 |
Curr. Mol. Med. |
pmid:22834825
|
Knapp M et al. |
Myocardial infarction changes sphingolipid metabolism in the uninfarcted ventricular wall of the rat. |
2012 |
Lipids |
pmid:22833182
|
Iwaki S et al. |
Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells. |
2012 Nov-Dec |
Biochim. Biophys. Acta |
pmid:22819712
|
Boussommier-Calleja A et al. |
Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyes. |
2012 |
Invest. Ophthalmol. Vis. Sci. |
pmid:22807298
|
Shea BS and Tager AM |
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis. |
2012 |
Proc Am Thorac Soc |
pmid:22802282
|
Pyne NJ et al. |
Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis. |
2013 |
Biochim. Biophys. Acta |
pmid:22801038
|
Orr Gandy KA and Obeid LM |
Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors. |
2013 |
Biochim. Biophys. Acta |
pmid:22801037
|
Chan H and Pitson SM |
Post-translational regulation of sphingosine kinases. |
2013 |
Biochim. Biophys. Acta |
pmid:22801036
|
Brizuela L et al. |
First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer. |
2012 |
Mol. Cancer Ther. |
pmid:22784711
|
Czarnota GJ et al. |
Tumor radiation response enhancement by acoustical stimulation of the vasculature. |
2012 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22778441
|
Nakahara T et al. |
Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway. |
2012 |
Fertil. Steril. |
pmid:22763095
|
Kotelevets N et al. |
Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. |
2012 |
PLoS ONE |
pmid:22761740
|
Zhang BL et al. |
Sphingosine 1-phosphate acts as an activator for the porcine Gpr3 of constitutively active G protein-coupled receptors. |
2012 |
J Zhejiang Univ Sci B |
pmid:22761247
|
Saba JD and de la Garza-Rodea AS |
S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase. |
2013 |
Biochim. Biophys. Acta |
pmid:22750505
|
Kharel Y et al. |
Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate. |
2012 |
Biochem. J. |
pmid:22747486
|
Che W et al. |
Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells. |
2012 |
Biochim. Biophys. Acta |
pmid:22743041
|
Karliner JS |
Sphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progress. |
2013 |
Biochim. Biophys. Acta |
pmid:22735359
|
Olivera A et al. |
Shaping the landscape: metabolic regulation of S1P gradients. |
2013 |
Biochim. Biophys. Acta |
pmid:22735358
|
Takuwa Y et al. |
Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases. |
2013 |
Biochim. Biophys. Acta |
pmid:22735357
|
Ohotski J et al. |
Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. |
2013 |
Int. J. Cancer |
pmid:22733311
|
Yokoyama K et al. |
Decrease of serum sphingosine-1-phosphate levels in hemodialysis patients with secondary hyperparathyroidism treated with cinacalcet. |
2012 |
Clin. Nephrol. |
pmid:22732343
|
Linke B et al. |
Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation. |
2012 |
Prostaglandins Other Lipid Mediat. |
pmid:22732087
|
Chiba K and Yoshii N |
[Pharmacological properties and clinical efficacy of fingolimod hydrochloride (Imusera®/Gilenya®) for the treatment of multiple sclerosis]. |
2012 |
Nippon Yakurigaku Zasshi |
pmid:22728990
|
Upadhyaya P et al. |
The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22727907
|
Hisano Y et al. |
Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. |
2012 |
PLoS ONE |
pmid:22723910
|
GarcÃa-Merino JA and Sánchez AJ |
[Basic mechanisms of action of fingolimod in relation to multiple sclerosis]. |
2012 |
Rev Neurol |
pmid:22718407
|
Testai FD et al. |
Changes in the cerebrospinal fluid ceramide profile after subarachnoid hemorrhage. |
2012 |
Stroke |
pmid:22713492
|
GarcÃa-Bernal D et al. |
Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function. |
2013 |
J. Pathol. |
pmid:22711564
|
Ponnusamy S et al. |
Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. |
2012 |
EMBO Mol Med |
pmid:22707406
|
Krishna SM et al. |
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model. |
2012 |
Am. J. Pathol. |
pmid:22698985
|
Ishii M and Kikuta J |
Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis. |
2013 |
Biochim. Biophys. Acta |
pmid:22691949
|
Lee SH et al. |
Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22679064
|
Shmyrev VI et al. |
[Sphingosine-1-phosphate signaling system and the innovative mechanism of action of fingolimod in treatment of multiple sclerosis: review of foreign literature]. |
2012 |
Zh Nevrol Psikhiatr Im S S Korsakova |
pmid:22677684
|
Takuwa Y et al. |
Sphingosine-1-phosphate signaling in physiology and diseases. |
2012 Sep-Oct |
Biofactors |
pmid:22674845
|
Li C et al. |
Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor. |
2012 |
J. Neurophysiol. |
pmid:22673325
|
Yang J et al. |
Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling. |
2012 |
Circulation |
pmid:22668972
|
Kunisawa J and Kiyono H |
Immunological function of sphingosine 1-phosphate in the intestine. |
2012 |
Nutrients |
pmid:22666543
|
Nijnik A et al. |
The role of sphingosine-1-phosphate transporter Spns2 in immune system function. |
2012 |
J. Immunol. |
pmid:22664872
|
Farahat WA et al. |
Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures. |
2012 |
PLoS ONE |
pmid:22662145
|
Sato C et al. |
Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22659743
|
Watson L et al. |
Increased serum concentration of sphingosine-1-phosphate in juvenile-onset systemic lupus erythematosus. |
2012 |
J. Clin. Immunol. |
pmid:22648459
|
Carr JM et al. |
Sphingosine kinase 1 in viral infections. |
2013 |
Rev. Med. Virol. |
pmid:22639116
|
Nakahara K et al. |
The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. |
2012 |
Mol. Cell |
pmid:22633490
|
Parrill AL et al. |
Structure of the first sphingosine 1-phosphate receptor. |
2012 |
Sci Signal |
pmid:22623751
|
Van Brocklyn JR and Williams JB |
The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death. |
2012 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:22613819
|