Pyne NJ et al. |
Sphingosine 1-phosphate signalling in cancer. |
2012 |
Biochem. Soc. Trans. |
pmid:22260672
|
Jin YX et al. |
A strategy for enrichment of the bioactive sphingoid base-1-phosphates produced by Hypericum perforatum L. in a balloon type airlift reactor. |
2012 |
Bioresour. Technol. |
pmid:22940331
|
Yu FX et al. |
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. |
2012 |
Cell |
pmid:22863277
|
Snider AJ et al. |
Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. |
2012 |
Prostaglandins Other Lipid Mediat. |
pmid:22940715
|
Moon MH et al. |
Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes. |
2012 |
Int. J. Mol. Med. |
pmid:22992945
|
Park TS and Goldberg IJ |
Sphingolipids, lipotoxic cardiomyopathy, and cardiac failure. |
2012 |
Heart Fail Clin |
pmid:22999245
|
Miller E et al. |
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. |
2012 |
Chem. Biol. |
pmid:22884261
|
Armstrong SM et al. |
Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac. |
2012 |
Am. J. Pathol. |
pmid:22203054
|
Bode C and Gräler MH |
Immune regulation by sphingosine 1-phosphate and its receptors. |
2012 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:22159476
|
Cyster JG and Schwab SR |
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. |
2012 |
Annu. Rev. Immunol. |
pmid:22149932
|
Kurata H et al. |
Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22153936
|
Calise S et al. |
Sphingosine 1-phosphate stimulates proliferation and migration of satellite cells: role of S1P receptors. |
2012 |
Biochim. Biophys. Acta |
pmid:22178384
|
Balczerski B et al. |
Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. |
2012 |
Dev. Biol. |
pmid:22185793
|
Witt W et al. |
Sphingosine-1-phosphate induces contraction of valvular interstitial cells from porcine aortic valves. |
2012 |
Cardiovasc. Res. |
pmid:22232739
|
Madhunapantula SV et al. |
Targeting sphingosine kinase-1 to inhibit melanoma. |
2012 |
Pigment Cell Melanoma Res |
pmid:22236408
|
Che W et al. |
Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells. |
2012 |
Biochim. Biophys. Acta |
pmid:22743041
|
Testai FD et al. |
Changes in the cerebrospinal fluid ceramide profile after subarachnoid hemorrhage. |
2012 |
Stroke |
pmid:22713492
|
GarcÃa-Merino JA and Sánchez AJ |
[Basic mechanisms of action of fingolimod in relation to multiple sclerosis]. |
2012 |
Rev Neurol |
pmid:22718407
|
Hisano Y et al. |
Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. |
2012 |
PLoS ONE |
pmid:22723910
|
Chiba K and Yoshii N |
[Pharmacological properties and clinical efficacy of fingolimod hydrochloride (Imusera®/Gilenya®) for the treatment of multiple sclerosis]. |
2012 |
Nippon Yakurigaku Zasshi |
pmid:22728990
|
Linke B et al. |
Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation. |
2012 |
Prostaglandins Other Lipid Mediat. |
pmid:22732087
|
Yokoyama K et al. |
Decrease of serum sphingosine-1-phosphate levels in hemodialysis patients with secondary hyperparathyroidism treated with cinacalcet. |
2012 |
Clin. Nephrol. |
pmid:22732343
|
Upadhyaya P et al. |
The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22727907
|
Sun DF et al. |
Sphingosine 1-phosphate antagonizes the effect of all-trans retinoic acid (ATRA) in a human colon cancer cell line by modulation of RARβ expression. |
2012 |
Cancer Lett. |
pmid:22261335
|
Park SW et al. |
Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury. |
2012 |
J. Am. Soc. Nephrol. |
pmid:22095950
|
Moberly JB et al. |
Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: results from a 12-week, open-label pilot study in multiple sclerosis patients. |
2012 |
J. Neuroimmunol. |
pmid:22465063
|
Li Q et al. |
The reduction of allograft arteriosclerosis in intestinal transplant is associated with sphingosine kinase 1/sphingosine-1-phosphate signaling after fish oil treatment. |
2012 |
Transplantation |
pmid:22466786
|
von Bismarck P et al. |
IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model. |
2012 |
Pulm Pharmacol Ther |
pmid:22469869
|
El-Shewy HM et al. |
Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells. |
2012 |
Mol. Endocrinol. |
pmid:22422617
|
Eisenhoffer GT et al. |
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. |
2012 |
Nature |
pmid:22504183
|
Peng P et al. |
[Effect of sphingosine-1-phosphate on chemotherapy-induced ovarian damage and on the efficacy of chemotherapy in mice bearing S180 tumor]. |
2012 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:22445989
|
Podbielska M et al. |
Signaling and regulatory functions of bioactive sphingolipids as therapeutic targets in multiple sclerosis. |
2012 |
Neurochem. Res. |
pmid:22451227
|
Altay O et al. |
Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. |
2012 |
Crit. Care Med. |
pmid:22488000
|
Tian YL et al. |
[Research progress of the selective sphingosine-1-phosphate receptor 1 agonists]. |
2012 |
Yao Xue Xue Bao |
pmid:22493799
|
Makino Y et al. |
Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle. |
2012 |
Allergol Int |
pmid:22441633
|
Shi Y et al. |
Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. |
2012 |
J. Hepatol. |
pmid:21756852
|
Spiegel S et al. |
Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. |
2012 |
Oncogene |
pmid:21725353
|
Krishna SM et al. |
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model. |
2012 |
Am. J. Pathol. |
pmid:22698985
|
Lee SH et al. |
Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22679064
|
Kim CH et al. |
Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors. |
2012 |
Leukemia |
pmid:21769103
|
Obinata H and Hla T |
Sphingosine 1-phosphate in coagulation and inflammation. |
2012 |
Semin Immunopathol |
pmid:21805322
|
Tencé M et al. |
Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists. |
2012 |
Cell. Signal. |
pmid:21872657
|
Beech DJ |
Integration of transient receptor potential canonical channels with lipids. |
2012 |
Acta Physiol (Oxf) |
pmid:21624095
|
Fujii Y et al. |
Blocking S1P interaction with S1Pâ‚ receptor by a novel competitive S1Pâ‚-selective antagonist inhibits angiogenesis. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22387544
|
Cantrell Stanford J et al. |
Sphingosine 1-phosphate (S1P) regulates glucose-stimulated insulin secretion in pancreatic beta cells. |
2012 |
J. Biol. Chem. |
pmid:22389505
|
Liu W et al. |
S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition. |
2012 |
Exp. Cell Res. |
pmid:22406263
|
Fukuhara S et al. |
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. |
2012 |
J. Clin. Invest. |
pmid:22406534
|
Yang F et al. |
Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis. |
2012 |
Cancer Biol. Ther. |
pmid:22406995
|
Kwak HI et al. |
Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation. |
2012 |
Angiogenesis |
pmid:22407449
|
Singh AT et al. |
Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization. |
2012 |
Reprod. Biomed. Online |
pmid:22197131
|
Pitman MR et al. |
Molecular targets of FTY720 (fingolimod). |
2012 |
Curr. Mol. Med. |
pmid:22834825
|
Karmouty-Quintana H et al. |
Treatment with a sphingosine-1-phosphate analog inhibits airway remodeling following repeated allergen exposure. |
2012 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:22287614
|
Curry FE et al. |
Erythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels. |
2012 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:22865384
|
Masuko K et al. |
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. |
2012 |
Int J Rheum Dis |
pmid:22898216
|
Schmitz EI et al. |
Sphingosine 1-phosphate protects primary human keratinocytes from apoptosis via nitric oxide formation through the receptor subtype S1P₃. |
2012 |
Mol. Cell. Biochem. |
pmid:22899173
|
Egom EE |
A therapeutic approach to hyperglycaemia in the setting of acute myocardial infarction: spotlight on glucagon-like peptide 1. |
2012 |
Ther Adv Cardiovasc Dis |
pmid:22902834
|
Liu Q et al. |
Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. |
2012 |
PLoS ONE |
pmid:22848628
|
Bassoy EY and Baran Y |
Bioactive sphingolipids in docetaxel-induced apoptosis in human prostate cancer cells. |
2012 |
Biomed. Pharmacother. |
pmid:22326625
|
Asghar MY et al. |
Sphingosine 1-phosphate and human ether-a'-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells. |
2012 |
Endocr. Relat. Cancer |
pmid:22889737
|
Kim BJ et al. |
Plasma sphingosine 1-phosphate levels and the risk of vertebral fracture in postmenopausal women. |
2012 |
J. Clin. Endocrinol. Metab. |
pmid:22879631
|
Beckham TH et al. |
Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. |
2012 |
Int. J. Cancer |
pmid:22322590
|
Törnquist K |
Sphingosine 1-phosphate, sphingosine kinase and autocrine calcium signalling in thyroid cells. |
2012 |
Acta Physiol (Oxf) |
pmid:21338471
|
Adamson RH et al. |
Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible. |
2012 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:22427519
|
Babahosseini H et al. |
Roles of bioactive sphingolipid metabolites in ovarian cancer cell biomechanics. |
2012 |
Conf Proc IEEE Eng Med Biol Soc |
pmid:23366417
|
Salata D et al. |
[Sphingosine-1-phosphate--molecular maestro]. |
2012 |
Postepy Biochem. |
pmid:23373414
|
Japtok L et al. |
Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtype. |
2012 |
PLoS ONE |
pmid:23145172
|
Zhang L et al. |
A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis. |
2012 |
J. Exp. Med. |
pmid:23148237
|
Korbelik M et al. |
Monitoring ceramide and sphingosine-1-phosphate levels in cancer cells and macrophages from tumours treated by photodynamic therapy. |
2012 |
Photochem. Photobiol. Sci. |
pmid:22354109
|
Bieberich E |
It's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation. |
2012 |
Neurochem. Res. |
pmid:22246226
|
Bhattacharya M et al. |
IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia. |
2012 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:22561460
|
Spohr TC et al. |
Sphingosine 1-phosphate-primed astrocytes enhance differentiation of neuronal progenitor cells. |
2012 |
J. Neurosci. Res. |
pmid:22588662
|
Parrill AL et al. |
Structure of the first sphingosine 1-phosphate receptor. |
2012 |
Sci Signal |
pmid:22623751
|
Giacomini MM et al. |
Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force. |
2012 |
Exp. Cell Res. |
pmid:22309779
|
Fernández-Pisonero I et al. |
Lipopolysaccharide and sphingosine-1-phosphate cooperate to induce inflammatory molecules and leukocyte adhesion in endothelial cells. |
2012 |
J. Immunol. |
pmid:23089395
|
Ma Y et al. |
Sphingosine-1-phosphate (S1P) mediates darkness-induced stomatal closure through raising cytosol pH and hydrogen peroxide (Hâ‚‚Oâ‚‚) levels in guard cells in Vicia faba. |
2012 |
Sci China Life Sci |
pmid:23090064
|
Taniguchi M et al. |
Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway. |
2012 |
J. Biol. Chem. |
pmid:23035115
|
Kawashima T et al. |
Contrary effects of sphingosine-1-phosphate on expression of α-smooth muscle actin in transforming growth factor β1-stimulated lung fibroblasts. |
2012 |
Eur. J. Pharmacol. |
pmid:23041148
|
Sorci-Thomas MG and Thomas MJ |
High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. |
2012 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:23077142
|
Yonesu K and Nara F |
[Anti-angiogenic effect of bioactive lipid antagonists]. |
2012 |
Nippon Rinsho |
pmid:23513926
|
Callihan P and Hooks SB |
Sphingosine-1-phosphate signaling in neural progenitors. |
2012 |
Methods Mol. Biol. |
pmid:22528449
|
Su SC and Bayless KJ |
Utilizing sphingosine-1-phosphate to stimulate sprouting angiogenesis. |
2012 |
Methods Mol. Biol. |
pmid:22528450
|
Lim M et al. |
The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries. |
2012 |
PLoS ONE |
pmid:22532844
|
Lynch KR |
Building a better sphingosine kinase-1 inhibitor. |
2012 |
Biochem. J. |
pmid:22533672
|
Mann DL |
Sphingosine 1-phosphate as a therapeutic target in heart failure: more questions than answers. |
2012 |
Circulation |
pmid:22534620
|
Reina E et al. |
Determination of sphingosine-1-phosphate lyase activity by gas chromatography coupled to electron impact mass spectrometry. |
2012 |
Chem. Phys. Lipids |
pmid:22265672
|
Meissner A et al. |
Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure. |
2012 |
Circulation |
pmid:22534621
|
Callihan P et al. |
Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells. |
2012 |
Neuropharmacology |
pmid:22016110
|
Maceyka M et al. |
Sphingosine-1-phosphate signaling and its role in disease. |
2012 |
Trends Cell Biol. |
pmid:22001186
|
Knapp M et al. |
Myocardial infarction differentially alters sphingolipid levels in plasma, erythrocytes and platelets of the rat. |
2012 |
Basic Res. Cardiol. |
pmid:22961594
|
Gupta VK et al. |
Focus on molecules: Sphingosine 1 Phosphate (S1P). |
2012 |
Exp. Eye Res. |
pmid:22001715
|
Shea BS and Tager AM |
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis. |
2012 |
Proc Am Thorac Soc |
pmid:22802282
|
Nakahara K et al. |
The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. |
2012 |
Mol. Cell |
pmid:22633490
|
Lim KG et al. |
Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival. |
2012 |
Br. J. Pharmacol. |
pmid:22251058
|
Shimizu T et al. |
Sphingosine-1-phosphate receptor 3 promotes neointimal hyperplasia in mouse iliac-femoral arteries. |
2012 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:22308044
|
Canals D et al. |
Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase. |
2012 |
J. Biol. Chem. |
pmid:22311981
|
Knapp M et al. |
Decreased free sphingoid base concentration in the plasma of patients with chronic systolic heart failure. |
2012 |
Adv Med Sci |
pmid:22296975
|
Nagahashi M et al. |
Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis. |
2012 |
Cancer Res. |
pmid:22298596
|
Ratajczak J et al. |
A novel view of paroxysmal nocturnal hemoglobinuria pathogenesis: more motile PNH hematopoietic stem/progenitor cells displace normal HSPCs from their niches in bone marrow due to defective adhesion, enhanced migration and mobilization in response to erythrocyte-released sphingosine-1 phosphate gradient. |
2012 |
Leukemia |
pmid:22343521
|
Mascall KS et al. |
Sphingosine-1-phosphate-induced release of TIMP-2 from vascular smooth muscle cells inhibits angiogenesis. |
2012 |
J. Cell. Sci. |
pmid:22344262
|
Hsu A et al. |
Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. |
2012 |
Int. J. Oncol. |
pmid:22344462
|