Pierre SC et al. |
PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate. |
2004 |
EMBO J. |
pmid:15257286
|
Roviezzo F et al. |
Human eosinophil chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15254297
|
Sauer B et al. |
Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes. |
2004 |
J. Biol. Chem. |
pmid:15247277
|
Sutphen R et al. |
Lysophospholipids are potential biomarkers of ovarian cancer. |
2004 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:15247129
|
Takeya H |
['Vegetable wasps and plant worms' and G-protein-coupled receptors]. |
2004 |
J. UOEH |
pmid:15244075
|
Li Y et al. |
Interaction of cortactin and Arp2/3 complex is required for sphingosine-1-phosphate-induced endothelial cell remodeling. |
2004 |
Exp. Cell Res. |
pmid:15242766
|
Misasi R et al. |
Prosaposin: a new player in cell death prevention of U937 monocytic cells. |
2004 |
Exp. Cell Res. |
pmid:15242760
|
Ikeda H et al. |
Sphingosine 1-phosphate enhances portal pressure in isolated perfused liver via S1P2 with Rho activation. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15240112
|
Maupas-Schwalm F et al. |
The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. |
2004 |
FASEB J. |
pmid:15231724
|
Barber SC et al. |
S1P and LPA trigger Schwann cell actin changes and migration. |
2004 |
Eur. J. Neurosci. |
pmid:15217370
|
Im DS et al. |
Enhancement of sphingosine 1-phosphate-induced phospholipase C activation during G(0)-G(1) transition in rat hepatocytes. |
2004 |
J. Pharmacol. Sci. |
pmid:15215654
|
Yokoo E et al. |
Sphingosine 1-phosphate inhibits migration of RBL-2H3 cells via S1P2: cross-talk between platelets and mast cells. |
2004 |
J. Biochem. |
pmid:15213242
|
Xu CB et al. |
Sphingosine signaling and atherogenesis. |
2004 |
Acta Pharmacol. Sin. |
pmid:15210056
|
Chavakis T et al. |
Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis. |
2004 |
FASEB J. |
pmid:15208269
|
Brinkmann V et al. |
FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. |
2004 |
Am. J. Transplant. |
pmid:15196057
|
Fujita T et al. |
Delta-catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1. |
2004 |
Biochem. J. |
pmid:15193146
|
Xin C et al. |
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses. |
2004 |
J. Biol. Chem. |
pmid:15192102
|
Geoffroy K et al. |
Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids. |
2004 |
J. Biol. Chem. |
pmid:15184394
|
Chae SS et al. |
Constitutive expression of the S1P1 receptor in adult tissues. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15165038
|
Butler J et al. |
Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15165029
|
Duong CQ et al. |
Expression of the lysophospholipid receptor family and investigation of lysophospholipid-mediated responses in human macrophages. |
2004 |
Biochim. Biophys. Acta |
pmid:15158762
|
Taha TA et al. |
Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. |
2004 |
Biochim. Biophys. Acta |
pmid:15158755
|
vom Dorp F et al. |
Inhibition of phospholipase C-epsilon by Gi-coupled receptors. |
2004 |
Cell. Signal. |
pmid:15157671
|
Pandey S and Assmann SM |
The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. |
2004 |
Plant Cell |
pmid:15155892
|
Hale JJ et al. |
Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15149705
|
Garg SK et al. |
Sphingosine 1-phosphate induces antimicrobial activity both in vitro and in vivo. |
2004 |
J. Infect. Dis. |
pmid:15143482
|
Miura Y et al. |
Independence of tumor necrosis factor-alpha-induced adhesion molecule expression from sphingosine 1-phosphate signaling in vascular endothelial cells. |
2004 |
J. Thromb. Haemost. |
pmid:15140149
|
Cui J et al. |
Role of ceramide in ischemic preconditioning. |
2004 |
J. Am. Coll. Surg. |
pmid:15110811
|
Lim HS et al. |
Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15109640
|
Meacci E et al. |
Sphingosine kinase activity is required for sphingosine-mediated phospholipase D activation in C2C12 myoblasts. |
2004 |
Biochem. J. |
pmid:15109308
|
Oshima Y et al. |
Intraocular gutless adenoviral-vectored VEGF stimulates anterior segment but not retinal neovascularization. |
2004 |
J. Cell. Physiol. |
pmid:15095287
|
Wang W et al. |
Physiological sphingosine 1-phosphate requirement for optimal activity of mouse CD4+ regulatory T Cells. |
2004 |
FASEB J. |
pmid:15084513
|
Hung RJ et al. |
Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15075215
|
Zhou H and Murthy KS |
Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15075212
|
Langlois S et al. |
Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation. |
2004 |
Blood |
pmid:15070679
|
Jolly PS et al. |
Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis. |
2004 |
J. Exp. Med. |
pmid:15067032
|
Mo FM et al. |
Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go-coupled receptor distinct from CB1, CB2 or EDG-1. |
2004 |
Eur. J. Pharmacol. |
pmid:15063151
|
Saba JD and Hla T |
Point-counterpoint of sphingosine 1-phosphate metabolism. |
2004 |
Circ. Res. |
pmid:15059942
|
Dudek SM et al. |
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. |
2004 |
J. Biol. Chem. |
pmid:15056655
|
Tanimoto T et al. |
Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells. |
2004 |
Circ. Res. |
pmid:15044318
|
Tokuda H et al. |
Interleukin (IL)-17 enhances tumor necrosis factor-alpha-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts. |
2004 |
J. Cell. Biochem. |
pmid:15034939
|
Peng X et al. |
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:15020292
|
Hammer S et al. |
Glucocorticoids mediate differential anti-apoptotic effects in human fibroblasts and keratinocytes via sphingosine-1-phosphate formation. |
2004 |
J. Cell. Biochem. |
pmid:14991774
|
Fukuda Y et al. |
Identification of PECAM-1 association with sphingosine kinase 1 and its regulation by agonist-induced phosphorylation. |
2004 |
Biochim. Biophys. Acta |
pmid:14984734
|
Goetzl EJ and Gräler MH |
Sphingosine 1-phosphate and its type 1 G protein-coupled receptor: trophic support and functional regulation of T lymphocytes. |
2004 |
J. Leukoc. Biol. |
pmid:14982946
|
Shimamura K et al. |
Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. |
2004 |
Eur. J. Pharmacol. |
pmid:14975703
|
Bencini C et al. |
Effects of sphingosine 1-phosphate on excitation-contraction coupling in mammalian skeletal muscle. |
2003 |
J. Muscle Res. Cell. Motil. |
pmid:14870969
|
Billich A and Ettmayer P |
Fluorescence-based assay of sphingosine kinases. |
2004 |
Anal. Biochem. |
pmid:14769343
|
Barnes PJ |
Ceramide lances the lungs. |
2004 |
Nat. Med. |
pmid:14760419
|
Harada J et al. |
Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells. |
2004 |
J. Neurochem. |
pmid:14756825
|
Forrest M et al. |
Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:14747617
|
Monick MM et al. |
Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus. |
2004 |
Am. J. Respir. Cell Mol. Biol. |
pmid:14742298
|
Matloubian M et al. |
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. |
2004 |
Nature |
pmid:14737169
|
Sanna MG et al. |
Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate. |
2004 |
J. Biol. Chem. |
pmid:14732717
|
Segura BJ et al. |
Sphingosine-1-phosphate mediates calcium signaling in guinea pig enteroglial cells. |
2004 |
J. Surg. Res. |
pmid:14732348
|
Renkl A et al. |
Distinct effects of sphingosine-1-phosphate, lysophosphatidic acid and histamine in human and mouse dendritic cells. |
2004 |
Int. J. Mol. Med. |
pmid:14719124
|
Ohmori T et al. |
Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. |
2004 |
J. Thromb. Haemost. |
pmid:14717991
|
Gräler MH and Goetzl EJ |
The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. |
2004 |
FASEB J. |
pmid:14715694
|
Usui S et al. |
Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5. |
2004 |
J. Biol. Chem. |
pmid:14711826
|
Berg C et al. |
Platelets induce reactive oxygen species-dependent growth of human skin fibroblasts. |
2003 |
Eur. J. Cell Biol. |
pmid:14703013
|
Ochi S et al. |
Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes. |
2004 |
J. Biol. Chem. |
pmid:14702348
|
Kohno T and Igarashi Y |
Truncation of the N-terminal ectodomain has implications in the N-glycosylation and transport to the cell surface of Edg-1/S1P1 receptor. |
2003 |
J. Biochem. |
pmid:14688232
|
Yue J et al. |
Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level. |
2004 |
Cell. Signal. |
pmid:14687668
|
Pacheco YM et al. |
Sphingosine 1-phosphate signal survival and mitogenesis are mediated by lipid-stereospecific binding of triacylglycerol-rich lipoproteins. |
2003 |
Cell. Mol. Life Sci. |
pmid:14685698
|
Baudhuin LM et al. |
S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR). |
2004 |
FASEB J. |
pmid:14657000
|
Shikata Y et al. |
Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. |
2003 |
FASEB J. |
pmid:14656986
|
Bayless KJ and Davis GE |
Sphingosine-1-phosphate markedly induces matrix metalloproteinase and integrin-dependent human endothelial cell invasion and lumen formation in three-dimensional collagen and fibrin matrices. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14651957
|
Yu N et al. |
Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes. |
2004 |
Glia |
pmid:14648542
|
Spiegel S and Milstien S |
Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. |
2003 |
Biochem. Soc. Trans. |
pmid:14641029
|
Wang J et al. |
[Sphingolipid and apoptosis]. |
2003 |
Sheng Li Ke Xue Jin Zhan |
pmid:14628466
|
Meyer zu Heringdorf D et al. |
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. |
2003 |
FEBS Lett. |
pmid:14623109
|
Otala M et al. |
Protection from radiation-induced male germ cell loss by sphingosine-1-phosphate. |
2004 |
Biol. Reprod. |
pmid:14613902
|
Castillo SS and Teegarden D |
Sphingosine-1-phosphate inhibition of apoptosis requires mitogen-activated protein kinase phosphatase-1 in mouse fibroblast C3H10T 1/2 cells. |
2003 |
J. Nutr. |
pmid:14608042
|
Einicker-Lamas M et al. |
Sphingosine-1-phosphate formation activates phosphatidylinositol-4 kinase in basolateral membranes from kidney cells: crosstalk in cell signaling through sphingolipids and phospholipids. |
2003 |
J. Biochem. |
pmid:14607979
|
Kim DS et al. |
Sphingosine-1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation. |
2004 |
Cell. Signal. |
pmid:14607279
|
Suomalainen L et al. |
Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. |
2003 |
J. Clin. Endocrinol. Metab. |
pmid:14602806
|
Ignatov A et al. |
Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14592418
|
Bernatchez PN et al. |
Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: role in cellular migration. |
2003 |
J. Cell. Biochem. |
pmid:14587028
|
Formigli L et al. |
Sphingosine 1-phosphate induces cell contraction via calcium-independent/Rho-dependent pathways in undifferentiated skeletal muscle cells. |
2004 |
J. Cell. Physiol. |
pmid:14584038
|
Sorensen SD et al. |
Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes. |
2003 |
Mol. Pharmacol. |
pmid:14573770
|
Rao TS et al. |
Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes. |
2003 |
Brain Res. |
pmid:14568343
|
Niedernberg A et al. |
Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors. |
2003 |
J Biomol Screen |
pmid:14567777
|
Kelley GG et al. |
Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins. |
2004 |
Biochem. J. |
pmid:14567755
|
Ozaki H et al. |
Sphingosine-1-phosphate signaling in endothelial activation. |
2003 |
J. Atheroscler. Thromb. |
pmid:14564080
|
Coussin F et al. |
Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels. |
2003 |
Biochem. Pharmacol. |
pmid:14563496
|
Kim DS et al. |
Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis. |
2003 |
Arch. Pharm. Res. |
pmid:14560924
|
Morii T and Weissbach L |
Sphingosine 1-phosphate and cell migration: resistance to angiogenesis inhibitors. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14550287
|
Esch SW et al. |
Sphingolipid profile in the CNS of the twitcher (globoid cell leukodystrophy) mouse: a lipidomics approach. |
2003 |
Cell. Mol. Biol. (Noisy-le-grand) |
pmid:14528915
|
Rosenfeldt HM et al. |
Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. |
2003 |
FASEB J. |
pmid:14519658
|
Clemens JJ et al. |
Synthesis of para-alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:14505636
|
Facchinetti MM et al. |
Differential branching of the sphingolipid metabolic pathways with the stage of development. Involvement of sphingosine kinase. |
2003 |
Biol. Neonate |
pmid:14504448
|
Dorsam G et al. |
Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. |
2003 |
J. Immunol. |
pmid:14500646
|
Clair T et al. |
Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate. |
2003 |
Cancer Res. |
pmid:14500380
|
Meacci E et al. |
Down-regulation of EDG5/S1P2 during myogenic differentiation results in the specific uncoupling of sphingosine 1-phosphate signalling to phospholipase D. |
2003 |
Biochim. Biophys. Acta |
pmid:14499732
|
Desai NN et al. |
Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation. |
1992 |
J. Biol. Chem. |
pmid:1429659
|
Sadahira Y et al. |
Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1409683
|
Deretic D et al. |
Phosphoinositides, ezrin/moesin, and rac1 regulate fusion of rhodopsin transport carriers in retinal photoreceptors. |
2004 |
Mol. Biol. Cell |
pmid:13679519
|
Djanani A et al. |
Agonist function of the neurokinin receptor antagonist, [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, in monocytes. |
2003 |
Regul. Pept. |
pmid:12972327
|
Olivera A et al. |
Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. |
2003 |
J. Biol. Chem. |
pmid:12963721
|
Van Brocklyn JR et al. |
Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells. |
2003 |
Cancer Lett. |
pmid:12963123
|