Buehrer BM and Bell RM |
Sphingosine kinase: properties and cellular functions. |
1993 |
Adv. Lipid Res. |
pmid:8397478
|
Olivera A and Spiegel S |
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. |
1993 |
Nature |
pmid:8413613
|
Fatatis A and Miller RJ |
Sphingosine and sphingosine 1-phosphate differentially modulate platelet-derived growth factor-BB-induced Ca2+ signaling in transformed oligodendrocytes. |
1996 |
J. Biol. Chem. |
pmid:8550576
|
Yatomi Y et al. |
N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets. |
1996 |
Biochemistry |
pmid:8555236
|
van Koppen C et al. |
Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate. |
1996 |
J. Biol. Chem. |
pmid:8567663
|
Spiegel S and Milstien S |
Sphingolipid metabolites: members of a new class of lipid second messengers. |
1995 |
J. Membr. Biol. |
pmid:8568838
|
Choi OH et al. |
Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor. |
1996 |
Nature |
pmid:8602265
|
Okajima F et al. |
Involvement of pertussis toxin-sensitive GTP-binding proteins in sphingosine 1-phosphate-induced activation of phospholipase C-Ca2+ system in HL60 leukemia cells. |
1996 |
FEBS Lett. |
pmid:8603702
|
Yamamura S et al. |
Sphingosine-1-phosphate inhibits actin nucleation and pseudopodium formation to control cell motility of mouse melanoma cells. |
1996 |
FEBS Lett. |
pmid:8612751
|
Pyne S et al. |
Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle. |
1996 |
Eur. J. Biochem. |
pmid:8647130
|
Van Koppen CJ et al. |
A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils. |
1996 |
Mol. Pharmacol. |
pmid:8649355
|
Cuvillier O et al. |
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. |
1996 |
Nature |
pmid:8657285
|
Waggoner DW et al. |
Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate. |
1996 |
J. Biol. Chem. |
pmid:8663293
|
Postma FR et al. |
Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. |
1996 |
EMBO J. |
pmid:8665846
|
Bünemann M et al. |
Activation of muscarinic K+ current in guinea-pig atrial myocytes by sphingosine-1-phosphate. |
1995 |
J. Physiol. (Lond.) |
pmid:8788935
|
Berger A et al. |
Structural requirements of sphingosylphosphocholine and sphingosine-1-phosphate for stimulation of activator protein-1 activity. |
1996 |
Mol. Pharmacol. |
pmid:8794881
|
Hashizume T et al. |
Sphingosine enhances phosphatidylinositol 4-kinase activity in rabbit platelets. |
1996 |
J. Biochem. |
pmid:8864845
|
Bünemann M et al. |
A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1-phosphate in atrial myocytes. |
1996 |
EMBO J. |
pmid:8896446
|
Meyer zu Heringdrof D et al. |
Calcium signalling by G protein-coupled sphingolipid receptors in bovine aortic endothelial cells. |
1996 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:8897440
|
Spiegel S and Merrill AH |
Sphingolipid metabolism and cell growth regulation. |
1996 |
FASEB J. |
pmid:8903509
|
Hung WC and Chuang LY |
Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8954076
|
Yang L et al. |
Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8954916
|
Okajima F et al. |
Sphingosine 1-phosphate stimulates hydrogen peroxide generation through activation of phospholipase C-Ca2+ system in FRTL-5 thyroid cells: possible involvement of guanosine triphosphate-binding proteins in the lipid signaling. |
1997 |
Endocrinology |
pmid:8977407
|
Chung T et al. |
ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate. |
1997 |
J. Biol. Chem. |
pmid:9006957
|
Mano N et al. |
Simultaneous quantitative determination method for sphingolipid metabolites by liquid chromatography/ionspray ionization tandem mass spectrometry. |
1997 |
Anal. Biochem. |
pmid:9025946
|
Yatomi Y et al. |
Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. |
1997 |
J. Biol. Chem. |
pmid:9030602
|
Rani CS et al. |
Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling. |
1997 |
J. Biol. Chem. |
pmid:9099730
|
Yatomi Y et al. |
Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues. |
1997 |
FEBS Lett. |
pmid:9119058
|
Törnquist K |
Sphingosine 1-phosphate stimulates Na+/H+ exchange in thyroid FRTL-5 cells. |
1997 |
Am. J. Physiol. |
pmid:9124507
|
Shirahama T et al. |
Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression. |
1997 |
FEBS Lett. |
pmid:9141489
|
Shatrov VA et al. |
Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9168973
|
Im DS et al. |
Characterization of sphingosine 1-phosphate-induced actions and its signaling pathways in rat hepatocytes. |
1997 |
Am. J. Physiol. |
pmid:9176218
|
Yamada T et al. |
Growth inhibition of human pancreatic cancer cells by sphingosylphosphorylcholine and influence of culture conditions. |
1997 |
Cell. Mol. Life Sci. |
pmid:9176562
|
Wang F et al. |
Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts. |
1997 |
Biochem. J. |
pmid:9182707
|
Yatomi Y et al. |
Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. |
1997 |
J. Biochem. |
pmid:9192741
|
Blakesley VA et al. |
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of Crk. |
1997 |
J. Biol. Chem. |
pmid:9195921
|
Kiss Z and Mukherjee JJ |
Phosphocholine and sphingosine-1-phosphate synergistically stimulate DNA synthesis by a MAP kinase-dependent mechanism. |
1997 |
FEBS Lett. |
pmid:9257719
|
Yamamura S et al. |
Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin-insensitive manner. |
1997 |
Biochemistry |
pmid:9271506
|
Edsall LC et al. |
Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. |
1997 |
J. Neurosci. |
pmid:9278531
|
Orlati S et al. |
Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism. |
1997 |
Biochim. Biophys. Acta |
pmid:9296526
|
Kozawa O et al. |
Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C. |
1997 |
J. Biol. Chem. |
pmid:9312119
|
Törnquist K et al. |
Sphingosine 1-phosphate mobilizes sequestered calcium, activates calcium entry, and stimulates deoxyribonucleic acid synthesis in thyroid FRTL-5 cells. |
1997 |
Endocrinology |
pmid:9322911
|
Saba JD et al. |
The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. |
1997 |
J. Biol. Chem. |
pmid:9334171
|
Kiss Z et al. |
Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine. |
1997 |
Biochem. J. |
pmid:9371692
|
Sato K et al. |
Exogenous sphingosine 1-phosphate induces neurite retraction possibly through a cell surface receptor in PC12 cells. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9388477
|
Kozawa O et al. |
Activation of mitogen-activated protein kinase is involved in sphingosine 1-phosphate-stimulated interleukin-6 synthesis in osteoblasts. |
1997 |
FEBS Lett. |
pmid:9414115
|
Mandala SM et al. |
Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9419344
|
Cuvillier O et al. |
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. |
1998 |
J. Biol. Chem. |
pmid:9446602
|
Conway AM et al. |
Sphingosine 1-phosphate activation of MAP kinase--involvement of PI 3-kinase and protein kinase C. |
1997 |
Biochem. Soc. Trans. |
pmid:9450013
|
Kawa S et al. |
Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate. |
1997 |
FEBS Lett. |
pmid:9459309
|
Zondag GC et al. |
Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. |
1998 |
Biochem. J. |
pmid:9480864
|
Lee MJ et al. |
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. |
1998 |
Science |
pmid:9488656
|
Takeda H et al. |
Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. |
1998 |
FEBS Lett. |
pmid:9490019
|
Igarashi Y |
Functional roles of sphingosine, sphingosine 1-phosphate, and methylsphingosines: in regard to membrane sphingolipid signaling pathways. |
1997 |
J. Biochem. |
pmid:9498549
|
Crilly KS et al. |
The choline kinase inhibitor hemicholinium-3 can inhibit mitogen-induced DNA synthesis independent of its effect on phosphocholine formation. |
1998 |
Arch. Biochem. Biophys. |
pmid:9521826
|
Spiegel S et al. |
Roles of sphingosine-1-phosphate in cell growth, differentiation, and death. |
1998 |
Biochemistry Mosc. |
pmid:9526097
|
Hamada K et al. |
Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9535736
|
Hisano N et al. |
Quantification of sphingosine derivatives in human platelets: inducible formation of free sphingosine. |
1998 |
J. Biochem. |
pmid:9538201
|
Melendez A et al. |
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. |
1998 |
J. Biol. Chem. |
pmid:9545263
|
Igarashi Y et al. |
Inhibition of mouse B16 melanoma cell motility by sphingosine-1-phosphate. |
1997 |
Adv. Exp. Med. Biol. |
pmid:9547620
|
Kleuser B et al. |
1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. |
1998 |
Cancer Res. |
pmid:9581819
|
Meyer zu Heringdorf D et al. |
Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors. |
1998 |
EMBO J. |
pmid:9582276
|
Himmel HM et al. |
Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells. |
1998 |
Mol. Pharmacol. |
pmid:9584212
|
Tas PW and Koschel K |
Sphingosine-1-phosphate induces a Ca2+ signal in primary rat astrocytes and a Ca2+ signal and shape changes in C6 rat glioma cells. |
1998 |
J. Neurosci. Res. |
pmid:9589387
|
Lanterman MM and Saba JD |
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. |
1998 |
Biochem. J. |
pmid:9601083
|
Nakamura H et al. |
Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells. |
1998 |
J. Biol. Chem. |
pmid:9624115
|
Noh SJ et al. |
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes. |
1998 |
J. Cell. Physiol. |
pmid:9648929
|
Van Brocklyn JR et al. |
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. |
1998 |
J. Cell Biol. |
pmid:9660876
|
Spiegel S et al. |
Sphingosine-1-phosphate in cell growth and cell death. |
1998 |
Ann. N. Y. Acad. Sci. |
pmid:9668339
|
Igarashi Y |
Sphingosine-1-phosphate as an intercellular signaling molecule. |
1998 |
Ann. N. Y. Acad. Sci. |
pmid:9668340
|
Stam JC et al. |
Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. |
1998 |
EMBO J. |
pmid:9670021
|
Nagiec MM et al. |
The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. |
1998 |
J. Biol. Chem. |
pmid:9677363
|
van Echten-Deckert G et al. |
Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts. |
1998 |
J. Biol. Chem. |
pmid:9722598
|
Edsall LC et al. |
N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide. |
1998 |
Biochemistry |
pmid:9737868
|
Kovács P et al. |
The effects of ceramide and its analogues on the secretion of the mucocyst content of Tetrahymena. |
1998 |
Cell. Mol. Biol. (Noisy-le-grand) |
pmid:9763202
|
Okamoto H et al. |
EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. |
1998 |
J. Biol. Chem. |
pmid:9765227
|
Vasta V et al. |
Effects of sphingosine 1-phosphate and bradykinin on phospholipid signalling in human epithelial A549 cells. |
1998 |
Biochem. Soc. Trans. |
pmid:9765948
|
Hida H et al. |
Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes. |
1998 |
J. Neurosci. |
pmid:9786978
|
Igarashi Y and Yatomi Y |
Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. |
1998 |
Acta Biochim. Pol. |
pmid:9821862
|
Guo C et al. |
Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. |
1998 |
Eur. J. Biochem. |
pmid:9826186
|
Xia P et al. |
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9826677
|
Goetzl EJ and An S |
Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. |
1998 |
FASEB J. |
pmid:9837849
|
MacDonell KL et al. |
Depression of excitability by sphingosine 1-phosphate in rat ventricular myocytes. |
1998 |
Am. J. Physiol. |
pmid:9843831
|
Chen PF et al. |
Ca2+ signaling induced by sphingosylphosphorylcholine and sphingosine 1-phosphate via distinct mechanisms in rat glomerular mesangial cells. |
1998 |
Kidney Int. |
pmid:9844123
|
Li S et al. |
Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes. |
1999 |
J. Lipid Res. |
pmid:9869657
|
Qiao L et al. |
Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP. |
1998 |
Bioorg. Med. Chem. Lett. |
pmid:9871527
|
Sato K et al. |
Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9878524
|
Sato K et al. |
Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. |
1999 |
Mol. Pharmacol. |
pmid:9882706
|
Yatomi Y et al. |
[Signal transduction related to sphingosine 1-phosphate]. |
1998 |
Tanpakushitsu Kakusan Koso |
pmid:9883680
|
Orlati S et al. |
Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. |
1998 |
Cell Calcium |
pmid:9924630
|
Sato K et al. |
Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor. |
1999 |
FEBS Lett. |
pmid:9928946
|
Hung WC et al. |
Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. |
1999 |
Biochem. J. |
pmid:9931312
|
Zhang G et al. |
Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. |
1999 |
Gene |
pmid:9931453
|
Alemany R et al. |
Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. |
1999 |
J. Biol. Chem. |
pmid:9933590
|
Goetzl EJ et al. |
Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. |
1999 |
J. Immunol. |
pmid:9973477
|
Van Brocklyn JR et al. |
Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. |
1999 |
J. Biol. Chem. |
pmid:9988698
|