Harvey K et al. |
Serum factors involved in human microvascular endothelial cell morphogenesis. |
2002 |
J. Lab. Clin. Med. |
pmid:12271276
|
Katsuma S et al. |
Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation. |
2002 |
Genes Cells |
pmid:12485162
|
Yun JK and Kester M |
Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation. |
2002 |
Arch. Biochem. Biophys. |
pmid:12485605
|
Hirafuji M et al. |
[Modulation of sphingosine 1-phosphate, a new lipid mediator, on nitric oxide production by vascular smooth muscle cells]. |
2002 |
Nippon Yakurigaku Zasshi |
pmid:12491784
|
Muraki K et al. |
[Effects of sphingosine-1-phosphate, a lipid mediator, in cardiovascular tissues]. |
2002 |
Nippon Yakurigaku Zasshi |
pmid:12491795
|
Graeler M and Goetzl EJ |
Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells. |
2002 |
FASEB J. |
pmid:12468451
|
Tanski W et al. |
Sphingosine-1-phosphate induces G(alphai)-coupled, PI3K/ras-dependent smooth muscle cell migration. |
2002 |
J. Surg. Res. |
pmid:12443721
|
Osada M et al. |
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12445827
|
Grey A et al. |
The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving G(i) proteins and phosphatidylinositol-3 kinase. |
2002 |
Endocrinology |
pmid:12446603
|
Ghelli A et al. |
Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta. |
2002 |
Biochem. J. |
pmid:12014986
|
Benaud CM et al. |
Deregulated activation of matriptase in breast cancer cells. |
2002 |
Clin. Exp. Metastasis |
pmid:12498394
|
Maceyka M et al. |
Sphingosine kinase, sphingosine-1-phosphate, and apoptosis. |
2002 |
Biochim. Biophys. Acta |
pmid:12531554
|
Chin TY et al. |
Distinct effects of different calcium-mobilizing agents on cell death in NG108-15 neuroblastoma X glioma cells. |
2002 |
Mol. Pharmacol. |
pmid:11854428
|
Meacci E et al. |
Sphingosine 1-phosphate evokes calcium signals in C2C12 myoblasts via Edg3 and Edg5 receptors. |
2002 |
Biochem. J. |
pmid:11853542
|
Lee M and Han SS |
Choline phosphate potentiates sphingosine-1-phosphate-induced Raf-1 kinase activation dependent of Ras--phosphatidylinositol-3-kinase pathway. |
2002 |
Cell. Signal. |
pmid:11858945
|
English D |
Do platelet-released phospholipids play a role in cardiovascular malformations and heritable coangulopathies? |
2002 |
Teratology |
pmid:11877771
|
Boguslawski G et al. |
Migration of vascular smooth muscle cells induced by sphingosine 1-phosphate and related lipids: potential role in the angiogenic response. |
2002 |
Exp. Cell Res. |
pmid:11900487
|
Hanafusa N et al. |
Sphingosine 1-phosphate stimulates rat mesangial cell proliferation from outside the cells. |
2002 |
Nephrol. Dial. Transplant. |
pmid:11917049
|
Idzko M et al. |
Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses. |
2002 |
FASEB J. |
pmid:11919175
|
Mandala S et al. |
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. |
2002 |
Science |
pmid:11923495
|
Wang J et al. |
Receptor-mediated activation of a Cl(-) current by LPA and S1P in cultured corneal keratocytes. |
2002 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12356825
|
Spiegel S and Milstien S |
Sphingosine 1-phosphate, a key cell signaling molecule. |
2002 |
J. Biol. Chem. |
pmid:12011102
|
Jin ZQ et al. |
Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts. |
2002 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12003800
|
Black JL and Johnson PR |
Factors controlling smooth muscle proliferation and airway remodelling. |
2002 |
Curr Opin Allergy Clin Immunol |
pmid:11964750
|
Brinkmann V et al. |
The immune modulator FTY720 targets sphingosine 1-phosphate receptors. |
2002 |
J. Biol. Chem. |
pmid:11967257
|
Liu H et al. |
Sphingosine kinases: a novel family of lipid kinases. |
2002 |
Prog. Nucleic Acid Res. Mol. Biol. |
pmid:12102559
|
Takuwa Y |
[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915348
|
Morales M |
[Participation of the phosphatidylinositol-3-kinase/Akt/endothelial-nitric-oxide synthase signaling in the processes of angiogenesis and vascular remodeling]. |
2002 |
Nefrologia |
pmid:12107910
|
Tsukahara T et al. |
[Molecular diversity of sphingosine kinase]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:11915350
|
Kim DS et al. |
Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes. |
2002 |
Cell. Signal. |
pmid:12034359
|
Rikitake Y et al. |
Involvement of endothelial nitric oxide in sphingosine-1-phosphate-induced angiogenesis. |
2002 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:11788469
|
Pyne S |
Cellular signaling by sphingosine and sphingosine 1-phosphate. Their opposing roles in apoptosis. |
2002 |
Subcell. Biochem. |
pmid:12037985
|
Graeler M et al. |
Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate. |
2002 |
J. Immunol. |
pmid:12370333
|
Takuwa Y et al. |
The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities. |
2002 |
J. Biochem. |
pmid:12038970
|
Meacci E et al. |
A role for calcium in sphingosine 1-phosphate-induced phospholipase D activity in C2C12 myoblasts. |
2002 |
FEBS Lett. |
pmid:12067705
|
Le Stunff H et al. |
Sphingosine-1-phosphate and lipid phosphohydrolases. |
2002 |
Biochim. Biophys. Acta |
pmid:12069805
|
Niedernberg A et al. |
Comparative analysis of human and rat S1P(5) (edg8): differential expression profiles and sensitivities to antagonists. |
2002 |
Biochem. Pharmacol. |
pmid:12234605
|
Payne SG et al. |
Sphingosine-1-phosphate: dual messenger functions. |
2002 |
FEBS Lett. |
pmid:12401202
|
Lampasso JD et al. |
Role of protein kinase C alpha in primary human osteoblast proliferation. |
2002 |
J. Bone Miner. Res. |
pmid:12412804
|
Napier JA et al. |
A new class of lipid desaturase central to sphingolipid biosynthesis and signalling. |
2002 |
Trends Plant Sci. |
pmid:12417141
|
Uhlenbrock K et al. |
Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors. |
2002 |
Cell. Signal. |
pmid:12220620
|
Tanimoto T et al. |
Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). |
2002 |
J. Biol. Chem. |
pmid:12226078
|
Porcelli AM et al. |
Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells. |
2002 |
Cell. Signal. |
pmid:11747992
|
Baudhuin LM et al. |
Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. |
2002 |
Mol. Pharmacol. |
pmid:12181443
|
Wang S et al. |
Two forms of membrane-bound sphingosine kinase in Tetrahymena and activity changes during growth and the cell cycle. |
2002 Jul-Aug |
J. Eukaryot. Microbiol. |
pmid:12188220
|
Young KW and Nahorski SR |
Sphingosine 1-phosphate: a Ca2+ release mediator in the balance. |
2002 Nov-Dec |
Cell Calcium |
pmid:12543093
|
Spiegel S and Milstien S |
Sphingosine-1-phosphate: an enigmatic signalling lipid. |
2003 |
Nat. Rev. Mol. Cell Biol. |
pmid:12728273
|
Takeya H et al. |
Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells. |
2003 |
Blood |
pmid:12730100
|
Mendel J et al. |
Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans. |
2003 |
J. Biol. Chem. |
pmid:12682045
|
Ignatov A et al. |
Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development. |
2003 |
J. Neurosci. |
pmid:12574419
|
Ikeda H et al. |
Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5. |
2003 |
Gastroenterology |
pmid:12557151
|
Rábano M et al. |
Sphingosine-1-phosphate stimulates cortisol secretion. |
2003 |
FEBS Lett. |
pmid:12560086
|
Florio T et al. |
Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis. |
2003 |
Mol. Pharmacol. |
pmid:12527801
|
Cho H et al. |
The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signalling. |
2003 |
Biochem. J. |
pmid:12564955
|
Jin Y et al. |
Sphingosine 1-phosphate is a novel inhibitor of T-cell proliferation. |
2003 |
Blood |
pmid:12586615
|
Dziak R et al. |
Effects of sphingosine-1-phosphate and lysophosphatidic acid on human osteoblastic cells. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12591009
|
Perry DK and Kolesnick RN |
Ceramide and sphingosine 1-phosphate in anti-cancer therapies. |
2003 |
Cancer Treat. Res. |
pmid:12613204
|
Johnson KR et al. |
Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability. |
2003 |
J. Biol. Chem. |
pmid:12815058
|
Deroanne C et al. |
EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway. |
2003 |
J. Cell. Sci. |
pmid:12615978
|
Pacheco YM et al. |
Sphingosine 1-phosphate signal survival and mitogenesis are mediated by lipid-stereospecific binding of triacylglycerol-rich lipoproteins. |
2003 |
Cell. Mol. Life Sci. |
pmid:14685698
|
Kohno T and Igarashi Y |
Truncation of the N-terminal ectodomain has implications in the N-glycosylation and transport to the cell surface of Edg-1/S1P1 receptor. |
2003 |
J. Biochem. |
pmid:14688232
|
Cho H et al. |
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. |
2003 |
FASEB J. |
pmid:12514120
|
Rosenfeldt HM et al. |
Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. |
2003 |
FASEB J. |
pmid:14519658
|
Waters C et al. |
Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells. |
2003 |
J. Biol. Chem. |
pmid:12480944
|
Lim HS et al. |
Syntheses of sphingosine-1-phosphate stereoisomers and analogues and their interaction with EDG receptors. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12482430
|
Shikata Y et al. |
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin. |
2003 |
J. Appl. Physiol. |
pmid:12482769
|
Laychock SG et al. |
Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells. |
2003 |
Diabetes |
pmid:12882914
|
Sauer B et al. |
Antiapoptotic action of 1alpha,25-dihydroxyvitamin D3 in primary human melanocytes. |
2003 |
Melanoma Res. |
pmid:12883359
|
Pettus BJ et al. |
The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. |
2003 |
FASEB J. |
pmid:12890694
|
Gratzinger D et al. |
Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho. |
2003 |
FASEB J. |
pmid:12890700
|
Muraki K and Imaizumi Y |
A novel action of palmitoyl-L-carnitine in human vascular endothelial cells. |
2003 |
J. Pharmacol. Sci. |
pmid:12890891
|
Annabi B et al. |
Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells. |
2003 |
Exp. Hematol. |
pmid:12842709
|
Djanani A et al. |
Agonist function of the neurokinin receptor antagonist, [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, in monocytes. |
2003 |
Regul. Pept. |
pmid:12972327
|
Bencini C et al. |
Effects of sphingosine 1-phosphate on excitation-contraction coupling in mammalian skeletal muscle. |
2003 |
J. Muscle Res. Cell. Motil. |
pmid:14870969
|
Shikata Y et al. |
Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. |
2003 |
FASEB J. |
pmid:14656986
|
Niedernberg A et al. |
Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors. |
2003 |
J Biomol Screen |
pmid:14567777
|
Rao TS et al. |
Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes. |
2003 |
Brain Res. |
pmid:14568343
|
Sorensen SD et al. |
Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes. |
2003 |
Mol. Pharmacol. |
pmid:14573770
|
Spiegel S and Milstien S |
Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. |
2003 |
Biochem. Soc. Trans. |
pmid:14641029
|
Ignatov A et al. |
Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14592418
|
Kim DS et al. |
Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis. |
2003 |
Arch. Pharm. Res. |
pmid:14560924
|
Coussin F et al. |
Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels. |
2003 |
Biochem. Pharmacol. |
pmid:14563496
|
Ozaki H et al. |
Sphingosine-1-phosphate signaling in endothelial activation. |
2003 |
J. Atheroscler. Thromb. |
pmid:14564080
|
Villullas IR et al. |
Characterisation of a sphingosine 1-phosphate-activated Ca2+ signalling pathway in human neuroblastoma cells. |
2003 |
J. Neurosci. Res. |
pmid:12836164
|
Schaphorst KL et al. |
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12626332
|
Malik ZA et al. |
Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. |
2003 |
J. Immunol. |
pmid:12626530
|
Mao C et al. |
Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides. |
2003 |
J. Biol. Chem. |
pmid:12783875
|
Chihab R et al. |
Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase. |
2003 |
Cell. Mol. Life Sci. |
pmid:12785724
|
Coursol S et al. |
Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins. |
2003 |
Nature |
pmid:12789341
|
Watterson K et al. |
Pleiotropic actions of sphingosine-1-phosphate. |
2003 |
Prog. Lipid Res. |
pmid:12790117
|
Bolz SS et al. |
Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway. |
2003 |
Circulation |
pmid:12796138
|
Kim JI et al. |
Sphingosine 1-phosphate in amniotic fluid modulates cyclooxygenase-2 expression in human amnion-derived WISH cells. |
2003 |
J. Biol. Chem. |
pmid:12796504
|
Thors B et al. |
Inhibition of Akt phosphorylation by thrombin, histamine and lysophosphatidylcholine in endothelial cells. Differential role of protein kinase C. |
2003 |
Atherosclerosis |
pmid:12801607
|
Yamaguchi H et al. |
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells. |
2003 |
Biochem. J. |
pmid:12803545
|
Miura S et al. |
Ras/Raf1-dependent signal in sphingosine-1-phosphate-induced tube formation in human coronary artery endothelial cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12821130
|
Vogler R et al. |
Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing. |
2003 |
J. Invest. Dermatol. |
pmid:12648236
|
Bollag WB |
Paradoxical effects of sphingosine-1-phosphate. |
2003 |
J. Invest. Dermatol. |
pmid:12648243
|
Uhlenbrock K et al. |
Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells. |
2003 |
Cell. Physiol. Biochem. |
pmid:12649592
|
Gómez-Muñoz A et al. |
Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages. |
2003 |
FEBS Lett. |
pmid:12650926
|
Kimura T et al. |
High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12775579
|