Knapp M |
Cardioprotective role of sphingosine-1-phosphate. |
2011 |
J. Physiol. Pharmacol. |
pmid:22314562
|
Berdyshev EV et al. |
Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. |
2011 |
Anal. Biochem. |
pmid:20804717
|
Mair N et al. |
Genetic evidence for involvement of neuronally expressed S1Pâ‚ receptor in nociceptor sensitization and inflammatory pain. |
2011 |
PLoS ONE |
pmid:21359147
|
Ishii T et al. |
The role of sphingosine 1-phosphate in migration of osteoclast precursors; an application of intravital two-photon microscopy. |
2011 |
Mol. Cells |
pmid:21360199
|
Antel J and Hohlfeld R |
Modulation of sphingosine 1-phosphate signaling in neurologic disease. |
2011 |
Neurology |
pmid:21360856
|
Hagen N et al. |
Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism. |
2011 |
Cell Death Differ. |
pmid:21331079
|
Meng H et al. |
Loss of sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia. |
2011 |
PLoS ONE |
pmid:22096531
|
Yuan L et al. |
[The study on protective effect of sphingosine-1-phosphate in cardiomyocytes]. |
2011 |
Zhongguo Ying Yong Sheng Li Xue Za Zhi |
pmid:22097726
|
Ling B et al. |
Sphingosine-1-phosphate: a potential therapeutic agent against human breast cancer. |
2011 |
Invest New Drugs |
pmid:20041340
|
Lépine S et al. |
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage. |
2011 |
J. Biol. Chem. |
pmid:22052905
|
Kotani M et al. |
[Bone and calcium update; bone research update. Trafficking of osteoclast precursors visualized by intravital imaging technology]. |
2011 |
Clin Calcium |
pmid:22133828
|
Jiang Z et al. |
Metabonomic study on women of reproductive age treated with nutritional intervention: screening potential biomarkers related to neural tube defects occurrence. |
2011 |
Biomed. Chromatogr. |
pmid:20812204
|
Durafourt BA et al. |
Differential responses of human microglia and blood-derived myeloid cells to FTY720. |
2011 |
J. Neuroimmunol. |
pmid:20826007
|
Fox TE et al. |
Circulating sphingolipid biomarkers in models of type 1 diabetes. |
2011 |
J. Lipid Res. |
pmid:21068007
|
Wang L et al. |
FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl. |
2011 |
Eur. Respir. J. |
pmid:21071472
|
Siow DL et al. |
Sphingosine kinase localization in the control of sphingolipid metabolism. |
2011 |
Adv. Enzyme Regul. |
pmid:21075134
|
Bieberich E |
There is more to a lipid than just being a fat: sphingolipid-guided differentiation of oligodendroglial lineage from embryonic stem cells. |
2011 |
Neurochem. Res. |
pmid:21136155
|
Kikuta J et al. |
S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis. |
2011 |
Rheumatol. Int. |
pmid:21113810
|
Hu PF et al. |
Sphingosine-1-phosphate: a potential therapeutic target for rheumatoid arthritis. |
2011 |
Mol. Biol. Rep. |
pmid:21116853
|
Xia P and Wadham C |
Sphingosine 1-phosphate, a key mediator of the cytokine network: juxtacrine signaling. |
2011 |
Cytokine Growth Factor Rev. |
pmid:21051273
|
Yu Y and Qin SC |
[An active lipid signaling molecule: sphingosine-1-phosphate and its biological characteristics]. |
2011 |
Sheng Li Ke Xue Jin Zhan |
pmid:21770269
|
Tanfin Z et al. |
ATP-binding cassette ABCC1 is involved in the release of sphingosine 1-phosphate from rat uterine leiomyoma ELT3 cells and late pregnant rat myometrium. |
2011 |
Cell. Signal. |
pmid:21803151
|
Gault CR and Obeid LM |
Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy. |
2011 |
Crit. Rev. Biochem. Mol. Biol. |
pmid:21787121
|
Qadri SM et al. |
Sphingosine but not sphingosine-1-phosphate stimulates suicidal erythrocyte death. |
2011 |
Cell. Physiol. Biochem. |
pmid:21865742
|
Kharel Y et al. |
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate. |
2011 |
Biochem. J. |
pmid:21848514
|
GarcÃa-Sáinz JA et al. |
Mechanisms involved in α1B-adrenoceptor desensitization. |
2011 |
IUBMB Life |
pmid:21815242
|
Yang Y and Uhlig S |
The role of sphingolipids in respiratory disease. |
2011 |
Ther Adv Respir Dis |
pmid:21900155
|
Edmonds Y et al. |
Development of small-molecule inhibitors of sphingosine-1-phosphate signaling. |
2011 |
Pharmacol. Ther. |
pmid:21906625
|
Baranowski M and Górski J |
Heart sphingolipids in health and disease. |
2011 |
Adv. Exp. Med. Biol. |
pmid:21910081
|
Hammad SM |
Blood sphingolipids in homeostasis and pathobiology. |
2011 |
Adv. Exp. Med. Biol. |
pmid:21910082
|
Serafimidis I et al. |
G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis. |
2011 |
Mol. Cell. Biol. |
pmid:21911471
|
Kim BS et al. |
The sphingosine-1-phosphate derivative NHOBTD inhibits angiogenesis both in vitro and in vivo. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21888894
|
Bedia C et al. |
Regulation of autophagy by sphingolipids. |
2011 |
Anticancer Agents Med Chem |
pmid:21707487
|
Weigert A et al. |
S1P regulation of macrophage functions in the context of cancer. |
2011 |
Anticancer Agents Med Chem |
pmid:21707489
|
Watters RJ et al. |
Targeting sphingosine-1-phosphate receptors in cancer. |
2011 |
Anticancer Agents Med Chem |
pmid:21707490
|
Stevenson CE et al. |
Targeting sphingosine-1-phosphate in hematologic malignancies. |
2011 |
Anticancer Agents Med Chem |
pmid:21707492
|
Bourquin F et al. |
PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism. |
2011 |
Protein Sci. |
pmid:21710479
|
Mathew B et al. |
Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. |
2011 |
FASEB J. |
pmid:21712494
|
Olivera A and Rivera J |
An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease. |
2011 |
Adv. Exp. Med. Biol. |
pmid:21713655
|
Vessey DA et al. |
P2X7 receptor agonists pre- and postcondition the heart against ischemia-reperfusion injury by opening pannexin-1/P2X₇ channels. |
2011 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:21685263
|
Varo-Sánchez GM et al. |
[Pharmacological targets in multiple sclerosis]. |
2011 |
Rev Neurol |
pmid:21678322
|
Alden KP et al. |
Sphingolipid long chain base phosphates can regulate apoptotic-like programmed cell death in plants. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21683064
|
Walzer T and Vivier E |
G-protein-coupled receptors in control of natural killer cell migration. |
2011 |
Trends Immunol. |
pmid:21664184
|
Poulsen RR et al. |
The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development. |
2011 |
BMC Dev. Biol. |
pmid:21668976
|
Goetzl EJ et al. |
Defective T cell chemotaxis to sphingosine 1-phosphate and chemokine CCL21 in idiopathic T lymphocytopenia. |
2011 |
J. Clin. Immunol. |
pmid:21671128
|
Donati C et al. |
Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6. |
2011 |
PLoS ONE |
pmid:21629665
|
Sánchez BA et al. |
Targeted analysis of sphingoid precursors in human biofluids by solid-phase extraction with in situ derivatization prior to μ-LC-LIF determination. |
2011 |
Anal Bioanal Chem |
pmid:21394454
|
Liu X et al. |
Essential roles of sphingosine 1-phosphate receptor types 1 and 3 in human hepatic stellate cells motility and activation. |
2011 |
J. Cell. Physiol. |
pmid:21660960
|
Li MH et al. |
Sphingolipid modulation of angiogenic factor expression in neuroblastoma. |
2011 |
Cancer Prev Res (Phila) |
pmid:21576349
|
Dickson MA et al. |
A phase I clinical trial of safingol in combination with cisplatin in advanced solid tumors. |
2011 |
Clin. Cancer Res. |
pmid:21257722
|
Kennedy AJ et al. |
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells. |
2011 |
J. Med. Chem. |
pmid:21495716
|
Samadi N et al. |
Regulation of lysophosphatidate signaling by autotaxin and lipid phosphate phosphatases with respect to tumor progression, angiogenesis, metastasis and chemo-resistance. |
2011 |
Biochimie |
pmid:20709140
|
Brecht K et al. |
Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2. |
2011 |
FASEB J. |
pmid:21450910
|
Benamer N et al. |
Electrophysiological and functional effects of sphingosine-1-phosphate in mouse ventricular fibroblasts. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21420933
|
Ocaña-Morgner C et al. |
Sphingosine 1-phosphate-induced motility and endocytosis of dendritic cells is regulated by SWAP-70 through RhoA. |
2011 |
J. Immunol. |
pmid:21421853
|
Kato K et al. |
Regulation by heat shock protein 27 of osteocalcin synthesis in osteoblasts. |
2011 |
Endocrinology |
pmid:21427224
|
López-Juárez A et al. |
Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. |
2011 |
Glia |
pmid:21319224
|
Yonamine I et al. |
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. |
2011 |
J. Cell Biol. |
pmid:21321100
|
Lamana A et al. |
CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells. |
2011 |
J. Invest. Dermatol. |
pmid:21412255
|
Yogi A et al. |
Sphingosine-1-phosphate-induced inflammation involves receptor tyrosine kinase transactivation in vascular cells: upregulation in hypertension. |
2011 |
Hypertension |
pmid:21383307
|
Zhu Q et al. |
A novel lipid natriuretic factor in the renal medulla: sphingosine-1-phosphate. |
2011 |
Am. J. Physiol. Renal Physiol. |
pmid:21478479
|
Takasugi N et al. |
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. |
2011 |
J. Neurosci. |
pmid:21543615
|
Jackson EK |
Role of sphingosine-1-phosphate in the renal medulla. |
2011 |
Am. J. Physiol. Renal Physiol. |
pmid:21511695
|
Salas A et al. |
Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. |
2011 |
Blood |
pmid:21527515
|
Cohen JA and Chun J |
Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. |
2011 |
Ann. Neurol. |
pmid:21520239
|
Lim KG et al. |
FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells. |
2011 |
J. Biol. Chem. |
pmid:21464128
|
Jung M et al. |
Anti-ageing effects of a new synthetic sphingolipid (K6EAA-L12) on aged murine skin. |
2011 |
Exp. Dermatol. |
pmid:21366697
|
Greenspon J et al. |
Sphingosine-1-phosphate regulates the expression of adherens junction protein E-cadherin and enhances intestinal epithelial cell barrier function. |
2011 |
Dig. Dis. Sci. |
pmid:20936358
|
Lan T et al. |
Simultaneous determination of sphingosine and sphingosine 1-phosphate in biological samples by liquid chromatography-tandem mass spectrometry. |
2011 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21292568
|
McQuiston T et al. |
Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages. |
2011 |
Microbiology (Reading, Engl.) |
pmid:21292747
|
Highkin MK et al. |
High-throughput screening assay for sphingosine kinase inhibitors in whole blood using RapidFire® mass spectrometry. |
2011 |
J Biomol Screen |
pmid:21297110
|
Bolli MH et al. |
Synthetic sphingosine 1-phosphate receptor modulators--opportunities and potential pitfalls. |
2011 |
Curr Top Med Chem |
pmid:21261590
|
Hopson KP et al. |
S1P activates store-operated calcium entry via receptor- and non-receptor-mediated pathways in vascular smooth muscle cells. |
2011 |
Am. J. Physiol., Cell Physiol. |
pmid:21270296
|
Ulrych T et al. |
Release of sphingosine-1-phosphate from human platelets is dependent on thromboxane formation. |
2011 |
J. Thromb. Haemost. |
pmid:21251196
|
Catarzi S et al. |
Redox regulation of ERK1/2 activation induced by sphingosine 1-phosphate in fibroblasts: involvement of NADPH oxidase and platelet-derived growth factor receptor. |
2011 |
Biochim. Biophys. Acta |
pmid:21256191
|
Beljanski V et al. |
Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts. |
2011 |
Cancer Biol. Ther. |
pmid:21258214
|
Doyle T et al. |
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats. |
2011 |
Pain |
pmid:21239112
|
Bouma HR et al. |
Low body temperature governs the decline of circulating lymphocytes during hibernation through sphingosine-1-phosphate. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21245336
|
Aarthi JJ et al. |
Dissecting the role of the S1P/S1PR axis in health and disease. |
2011 |
J. Dent. Res. |
pmid:21248363
|
Cahalan SM et al. |
Actions of a picomolar short-acting S1Pâ‚ agonist in S1Pâ‚-eGFP knock-in mice. |
2011 |
Nat. Chem. Biol. |
pmid:21445057
|
Sassoli C et al. |
Effects of S1P on skeletal muscle repair/regeneration during eccentric contraction. |
2011 |
J. Cell. Mol. Med. |
pmid:21199328
|
Jang S et al. |
Modulation of sphingosine 1-phosphate and tyrosine hydroxylase in the stress-induced anxiety. |
2011 |
Neurochem. Res. |
pmid:21076868
|
Hisano Y et al. |
The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720. |
2011 |
J. Biol. Chem. |
pmid:21084291
|
Bäumer W et al. |
Decreased concentration and enhanced metabolism of sphingosine-1-phosphate in lesional skin of dogs with atopic dermatitis: disturbed sphingosine-1-phosphate homeostasis in atopic dermatitis. |
2011 |
J. Invest. Dermatol. |
pmid:20811395
|
Majeed Y et al. |
Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids. |
2011 |
Br. J. Pharmacol. |
pmid:21108630
|
Chiba Y et al. |
Sphingosine-1-phosphate augments agonist-mediated contraction in the bronchial smooth muscles of mice. |
2011 |
Pharmacol Rep |
pmid:21602610
|
Doyle T et al. |
Sphingosine-1-phosphate acting via the S1Pâ‚ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia. |
2011 |
Neurosci. Lett. |
pmid:21605625
|
Christoffersen C et al. |
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21606363
|
Fenger M et al. |
Genetics of the ceramide/sphingosine-1-phosphate rheostat in blood pressure regulation and hypertension. |
2011 |
BMC Genet. |
pmid:21569466
|
Lan T et al. |
Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells. |
2011 |
Mol. Endocrinol. |
pmid:21998146
|
Kang H et al. |
Fluid shear stress and sphingosine 1-phosphate activate calpain to promote membrane type 1 matrix metalloproteinase (MT1-MMP) membrane translocation and endothelial invasion into three-dimensional collagen matrices. |
2011 |
J. Biol. Chem. |
pmid:22002053
|
Gomez L et al. |
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection. |
2011 |
Basic Res. Cardiol. |
pmid:22002221
|
Yester JW et al. |
Extracellular and intracellular sphingosine-1-phosphate in cancer. |
2011 |
Cancer Metastasis Rev. |
pmid:22002715
|
Pyne S et al. |
Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules. |
2011 |
Cancer Res. |
pmid:21940750
|
McGuire PG et al. |
Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier. |
2011 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:21940944
|
Karuna R et al. |
Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism. |
2011 |
Atherosclerosis |
pmid:21944699
|
Arnon TI et al. |
GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. |
2011 |
Science |
pmid:21960637
|
El-Shewy HM et al. |
Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. |
2011 |
Mol. Endocrinol. |
pmid:22016563
|
Sola A et al. |
Sphingosine-1-phosphate signalling induces the production of Lcn-2 by macrophages to promote kidney regeneration. |
2011 |
J. Pathol. |
pmid:22025214
|
Wirrig C et al. |
Sphingosylphosphorylcholine is a proinflammatory mediator in cerebral arteries. |
2011 |
J. Cereb. Blood Flow Metab. |
pmid:20551970
|