Pandey S and Assmann SM |
The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling. |
2004 |
Plant Cell |
pmid:15155892
|
Taha TA et al. |
Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. |
2004 |
Biochim. Biophys. Acta |
pmid:15158755
|
Duong CQ et al. |
Expression of the lysophospholipid receptor family and investigation of lysophospholipid-mediated responses in human macrophages. |
2004 |
Biochim. Biophys. Acta |
pmid:15158762
|
Zhou H and Murthy KS |
Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15075212
|
Hung RJ et al. |
Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts. |
2004 |
Am. J. Physiol., Cell Physiol. |
pmid:15075215
|
Wang W et al. |
Physiological sphingosine 1-phosphate requirement for optimal activity of mouse CD4+ regulatory T Cells. |
2004 |
FASEB J. |
pmid:15084513
|
Dudek SM et al. |
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. |
2004 |
J. Biol. Chem. |
pmid:15056655
|
Saba JD and Hla T |
Point-counterpoint of sphingosine 1-phosphate metabolism. |
2004 |
Circ. Res. |
pmid:15059942
|
Miura Y et al. |
Independence of tumor necrosis factor-alpha-induced adhesion molecule expression from sphingosine 1-phosphate signaling in vascular endothelial cells. |
2004 |
J. Thromb. Haemost. |
pmid:15140149
|
Garg SK et al. |
Sphingosine 1-phosphate induces antimicrobial activity both in vitro and in vivo. |
2004 |
J. Infect. Dis. |
pmid:15143482
|
Hale JJ et al. |
Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15149705
|
Oshima Y et al. |
Intraocular gutless adenoviral-vectored VEGF stimulates anterior segment but not retinal neovascularization. |
2004 |
J. Cell. Physiol. |
pmid:15095287
|
Peng X et al. |
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:15020292
|
Panetti TS et al. |
Extracellular matrix molecules regulate endothelial cell migration stimulated by lysophosphatidic acid. |
2004 |
J. Thromb. Haemost. |
pmid:15333043
|
Renkl A et al. |
Distinct effects of sphingosine-1-phosphate, lysophosphatidic acid and histamine in human and mouse dendritic cells. |
2004 |
Int. J. Mol. Med. |
pmid:14719124
|
Jin ZQ et al. |
Sphingosine kinase activation mediates ischemic preconditioning in murine heart. |
2004 |
Circulation |
pmid:15451787
|
Galaria II et al. |
Differential regulation of ERK1/2 and p38(MAPK) by components of the Rho signaling pathway during sphingosine-1-phosphate-induced smooth muscle cell migration. |
2004 |
J. Surg. Res. |
pmid:15555614
|
Shida D et al. |
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells. |
2004 |
FEBS Lett. |
pmid:15556605
|
Allende ML et al. |
Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. |
2004 |
J. Biol. Chem. |
pmid:15459201
|
Yamanaka M et al. |
Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation. |
2004 |
J. Biol. Chem. |
pmid:15485866
|
Alewijnse AE et al. |
Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites. |
2004 |
Br. J. Pharmacol. |
pmid:15504747
|
Bhattacharya J |
Lung injury: sphingosine-1-phosphate to the rescue. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:15504814
|
Hedemann J et al. |
Comparison of noradrenaline and lysosphingolipid-induced vasoconstriction in mouse and rat small mesenteric arteries. |
2004 |
Auton Autacoid Pharmacol |
pmid:15541015
|
Kumar A et al. |
Sphingosine-1-phosphate plays a role in the suppression of lateral pseudopod formation during Dictyostelium discoideum cell migration and chemotaxis. |
2004 |
Cell Motil. Cytoskeleton |
pmid:15476260
|
Liu S et al. |
Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. |
2004 |
J. Biol. Chem. |
pmid:15466414
|
Birukov KG et al. |
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. |
2004 |
Circ. Res. |
pmid:15472119
|
Xin C et al. |
Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells. |
2004 |
Br. J. Pharmacol. |
pmid:15466446
|
Butler J et al. |
Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15165029
|
Chae SS et al. |
Constitutive expression of the S1P1 receptor in adult tissues. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15165038
|
Geoffroy K et al. |
Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids. |
2004 |
J. Biol. Chem. |
pmid:15184394
|
Xin C et al. |
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses. |
2004 |
J. Biol. Chem. |
pmid:15192102
|
Baudhuin LM et al. |
S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR). |
2004 |
FASEB J. |
pmid:14657000
|
Roth Z and Hansen PJ |
Sphingosine 1-phosphate protects bovine oocytes from heat shock during maturation. |
2004 |
Biol. Reprod. |
pmid:15317688
|
Hemmings DG et al. |
Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats. |
2004 |
Br. J. Pharmacol. |
pmid:15326035
|
McVerry BJ et al. |
Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:15282202
|
Ogretmen B and Hannun YA |
Biologically active sphingolipids in cancer pathogenesis and treatment. |
2004 |
Nat. Rev. Cancer |
pmid:15286740
|
Sutphen R et al. |
Lysophospholipids are potential biomarkers of ovarian cancer. |
2004 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:15247129
|
Sauer B et al. |
Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes. |
2004 |
J. Biol. Chem. |
pmid:15247277
|
Roviezzo F et al. |
Human eosinophil chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate. |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15254297
|
Hla T |
Physiological and pathological actions of sphingosine 1-phosphate. |
2004 |
Semin. Cell Dev. Biol. |
pmid:15271296
|
Payne SG et al. |
Modulation of adaptive immune responses by sphingosine-1-phosphate. |
2004 |
Semin. Cell Dev. Biol. |
pmid:15271297
|
Oskouian B and Saba JD |
Death and taxis: what non-mammalian models tell us about sphingosine-1-phosphate. |
2004 |
Semin. Cell Dev. Biol. |
pmid:15271298
|
Bolz SS and Pohl U |
Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction. |
2003 Jul-Aug |
J. Vasc. Res. |
pmid:12913332
|
Dantas AP et al. |
Sphingosine 1-phosphate and control of vascular tone. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12742827
|
Itagaki K and Hauser CJ |
Sphingosine 1-phosphate, a diffusible calcium influx factor mediating store-operated calcium entry. |
2003 |
J. Biol. Chem. |
pmid:12746430
|
Kim DS et al. |
Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation. |
2003 |
J. Cell. Sci. |
pmid:12665551
|
Ohmori T et al. |
Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. |
2003 |
Cardiovasc. Res. |
pmid:12667959
|
Muraki K |
[Analyses of Ca-related ion channel currents and their involvement in Ca mobilization in smooth muscle and endothelial cells]. |
2003 |
Nippon Yakurigaku Zasshi |
pmid:12673948
|
Spiegel S and Milstien S |
Sphingosine-1-phosphate: an enigmatic signalling lipid. |
2003 |
Nat. Rev. Mol. Cell Biol. |
pmid:12728273
|
Takeya H et al. |
Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells. |
2003 |
Blood |
pmid:12730100
|
Mendel J et al. |
Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans. |
2003 |
J. Biol. Chem. |
pmid:12682045
|
Ignatov A et al. |
Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development. |
2003 |
J. Neurosci. |
pmid:12574419
|
Ikeda H et al. |
Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5. |
2003 |
Gastroenterology |
pmid:12557151
|
Rábano M et al. |
Sphingosine-1-phosphate stimulates cortisol secretion. |
2003 |
FEBS Lett. |
pmid:12560086
|
Johnson KR et al. |
Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability. |
2003 |
J. Biol. Chem. |
pmid:12815058
|
Meyer zu Heringdorf D et al. |
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. |
2003 |
FEBS Lett. |
pmid:14623109
|
Pacheco YM et al. |
Sphingosine 1-phosphate signal survival and mitogenesis are mediated by lipid-stereospecific binding of triacylglycerol-rich lipoproteins. |
2003 |
Cell. Mol. Life Sci. |
pmid:14685698
|
Kohno T and Igarashi Y |
Truncation of the N-terminal ectodomain has implications in the N-glycosylation and transport to the cell surface of Edg-1/S1P1 receptor. |
2003 |
J. Biochem. |
pmid:14688232
|
Jeng YJ et al. |
Regulation of oxytocin receptor expression in cultured human myometrial cells by fetal bovine serum and lysophospholipids. |
2003 |
Endocrinology |
pmid:12488330
|
Malchinkhuu E et al. |
Assessment of the role of sphingosine 1-phosphate and its receptors in high-density lipoprotein-induced stimulation of astroglial cell function. |
2003 |
Biochem. J. |
pmid:12470300
|
Suomalainen L et al. |
Sphingosine-1-phosphate in inhibition of male germ cell apoptosis in the human testis. |
2003 |
J. Clin. Endocrinol. Metab. |
pmid:14602806
|
Yamagata K et al. |
Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes. |
2003 |
Glia |
pmid:12509810
|
Einicker-Lamas M et al. |
Sphingosine-1-phosphate formation activates phosphatidylinositol-4 kinase in basolateral membranes from kidney cells: crosstalk in cell signaling through sphingolipids and phospholipids. |
2003 |
J. Biochem. |
pmid:14607979
|
Cho H et al. |
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. |
2003 |
FASEB J. |
pmid:12514120
|
Waters C et al. |
Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells. |
2003 |
J. Biol. Chem. |
pmid:12480944
|
Lim HS et al. |
Syntheses of sphingosine-1-phosphate stereoisomers and analogues and their interaction with EDG receptors. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12482430
|
Shikata Y et al. |
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin. |
2003 |
J. Appl. Physiol. |
pmid:12482769
|
Annabi B et al. |
Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells. |
2003 |
Exp. Hematol. |
pmid:12842709
|
Berg C et al. |
Platelets induce reactive oxygen species-dependent growth of human skin fibroblasts. |
2003 |
Eur. J. Cell Biol. |
pmid:14703013
|
Wang J et al. |
[Sphingolipid and apoptosis]. |
2003 |
Sheng Li Ke Xue Jin Zhan |
pmid:14628466
|
Esch SW et al. |
Sphingolipid profile in the CNS of the twitcher (globoid cell leukodystrophy) mouse: a lipidomics approach. |
2003 |
Cell. Mol. Biol. (Noisy-le-grand) |
pmid:14528915
|
Djanani A et al. |
Agonist function of the neurokinin receptor antagonist, [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, in monocytes. |
2003 |
Regul. Pept. |
pmid:12972327
|
Brailoiu E et al. |
Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP). |
2003 |
Biochem. J. |
pmid:12749764
|
Bernatchez PN et al. |
Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: role in cellular migration. |
2003 |
J. Cell. Biochem. |
pmid:14587028
|
Niedernberg A et al. |
Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors. |
2003 |
J Biomol Screen |
pmid:14567777
|
Rao TS et al. |
Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes. |
2003 |
Brain Res. |
pmid:14568343
|
Sorensen SD et al. |
Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes. |
2003 |
Mol. Pharmacol. |
pmid:14573770
|
Spiegel S and Milstien S |
Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. |
2003 |
Biochem. Soc. Trans. |
pmid:14641029
|
Ignatov A et al. |
Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14592418
|
Kim DS et al. |
Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis. |
2003 |
Arch. Pharm. Res. |
pmid:14560924
|
Coussin F et al. |
Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels. |
2003 |
Biochem. Pharmacol. |
pmid:14563496
|
Ozaki H et al. |
Sphingosine-1-phosphate signaling in endothelial activation. |
2003 |
J. Atheroscler. Thromb. |
pmid:14564080
|
Bayless KJ and Davis GE |
Sphingosine-1-phosphate markedly induces matrix metalloproteinase and integrin-dependent human endothelial cell invasion and lumen formation in three-dimensional collagen and fibrin matrices. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14651957
|
Morii T and Weissbach L |
Sphingosine 1-phosphate and cell migration: resistance to angiogenesis inhibitors. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14550287
|
Högback S et al. |
Ceramide 1-phosphate increases intracellular free calcium concentrations in thyroid FRTL-5 cells: evidence for an effect mediated by inositol 1,4,5-trisphosphate and intracellular sphingosine 1-phosphate. |
2003 |
Biochem. J. |
pmid:12416995
|
Frohnert PW et al. |
Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve. |
2003 |
J. Neuropathol. Exp. Neurol. |
pmid:12769191
|
Hakogi T et al. |
Synthesis of fluorescence-labeled sphingosine and sphingosine 1-phosphate; effective tools for sphingosine and sphingosine 1-phosphate behavior. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12639553
|
Arikawa K et al. |
Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity. |
2003 |
J. Biol. Chem. |
pmid:12810709
|
Meacci E et al. |
Sphingosine 1-phosphate signal transduction in muscle cells. |
2003 |
Ital. J. Biochem. |
pmid:12833634
|
Villullas IR et al. |
Characterisation of a sphingosine 1-phosphate-activated Ca2+ signalling pathway in human neuroblastoma cells. |
2003 |
J. Neurosci. Res. |
pmid:12836164
|
Schaphorst KL et al. |
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12626332
|
Malik ZA et al. |
Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. |
2003 |
J. Immunol. |
pmid:12626530
|
Mao C et al. |
Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides. |
2003 |
J. Biol. Chem. |
pmid:12783875
|
Chihab R et al. |
Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase. |
2003 |
Cell. Mol. Life Sci. |
pmid:12785724
|
Coursol S et al. |
Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins. |
2003 |
Nature |
pmid:12789341
|
Watterson K et al. |
Pleiotropic actions of sphingosine-1-phosphate. |
2003 |
Prog. Lipid Res. |
pmid:12790117
|
Rosen H and Liao J |
Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm. |
2003 |
Curr Opin Chem Biol |
pmid:12941420
|
Fegley AJ et al. |
Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation. |
2003 |
J. Surg. Res. |
pmid:12943808
|
Lu X et al. |
Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: differential interaction with protein targets. |
2003 |
J. Org. Chem. |
pmid:12946147
|
zu Heringdorf DM et al. |
Inhibition of Ca(2+) signalling by the sphingosine 1-phosphate receptor S1P(1). |
2003 |
Cell. Signal. |
pmid:12742228
|