Hornuss C et al. |
Human and rat alveolar macrophages express multiple EDG receptors. |
2001 |
Eur. J. Pharmacol. |
pmid:11698050
|
Yoshida A and Ueda H |
Neurobiology of the Edg2 lysophosphatidic acid receptor. |
2001 |
Jpn. J. Pharmacol. |
pmid:11700008
|
Im DS et al. |
Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. |
2001 |
Biochemistry |
pmid:11705398
|
Rosenfeldt HM et al. |
The sphingosine-1-phosphate receptor EDG-1 is essential for platelet-derived growth factor-induced cell motility. |
2001 |
Biochem. Soc. Trans. |
pmid:11709084
|
Manggau M et al. |
1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate. |
2001 |
J. Invest. Dermatol. |
pmid:11710939
|
Rosenfeldt HM et al. |
EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. |
2001 |
FASEB J. |
pmid:11726541
|
Lampasso JD et al. |
Sphingosine-1-phosphate effects on PKC isoform expression in human osteoblastic cells. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728164
|
Hla T et al. |
Lysophospholipids--receptor revelations. |
2001 |
Science |
pmid:11729304
|
Muraki K and Imaizumi Y |
A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells. |
2001 |
J. Physiol. (Lond.) |
pmid:11731576
|
Lee MJ et al. |
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. |
2001 |
Mol. Cell |
pmid:11583630
|
Li G et al. |
Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum. |
2001 |
Development |
pmid:11566853
|
Bischoff A et al. |
Nifedipine inhibits sphinogosine-1-phosphate-induced renovascular contraction in vitro and in vivo. |
2001 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:11534858
|
Sullards MC and Merrill AH |
Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. |
2001 |
Sci. STKE |
pmid:11752637
|
Okajima F |
[Establishment of the method for the measurement of sphingosine-1-phosphate in biological samples and its application for S1P research]. |
2001 |
Nippon Yakurigaku Zasshi |
pmid:11778456
|
Goetzl EJ |
Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324701
|
Olivera A and Spiegel S |
Sphingosine kinase: a mediator of vital cellular functions. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324702
|
Hla T |
Sphingosine 1-phosphate receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324703
|
Mandala SM |
Sphingosine-1-phosphate phosphatases. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324704
|
Lynch KR and Macdonald TL |
Structure activity relationships of lysophospholipid mediators. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324706
|
Panetti TS et al. |
Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11324710
|
Alderton F et al. |
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells. |
2001 |
J. Biol. Chem. |
pmid:11278307
|
Igarashi J et al. |
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278407
|
Morales-Ruiz M et al. |
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. |
2001 |
J. Biol. Chem. |
pmid:11278592
|
Birchwood CJ et al. |
Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. |
2001 |
J. Biol. Chem. |
pmid:11278643
|
Ng CK et al. |
Drought-induced guard cell signal transduction involves sphingosine-1-phosphate. |
2001 |
Nature |
pmid:11279499
|
Kranenburg O and Moolenaar WH |
Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists. |
2001 |
Oncogene |
pmid:11313900
|
Takuwa Y et al. |
Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11377814
|
Nanjundan M and Possmayer F |
Characterization of the pulmonary N-ethylmaleimide-insensitive phosphatidate phosphohydrolase. |
2000 Jul-Aug |
Exp. Lung Res. |
pmid:10914334
|
Pyne S and Pyne NJ |
Sphingosine 1-phosphate signalling in mammalian cells. |
2000 |
Biochem. J. |
pmid:10880336
|
Sharma C et al. |
Inhibition of Ca2+ release channel (ryanodine receptor) activity by sphingolipid bases: mechanism of action. |
2000 |
Chem. Phys. Lipids |
pmid:10660207
|
Vasta V et al. |
Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells. |
2000 |
Biochim. Biophys. Acta |
pmid:10601704
|
An S et al. |
Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. |
2000 |
J. Biol. Chem. |
pmid:10617617
|
Pyne S and Pyne N |
Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors. |
2000 |
Pharmacol. Ther. |
pmid:11150592
|
Conway A et al. |
Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells. |
2000 |
Cell. Signal. |
pmid:11152959
|
Olivera A et al. |
Assaying sphingosine kinase activity. |
2000 |
Meth. Enzymol. |
pmid:10563328
|
Brindley DN et al. |
Analysis of ceramide 1-phosphate and sphingosine-1-phosphate phosphatase activities. |
2000 |
Meth. Enzymol. |
pmid:10563330
|
Rümenapp U et al. |
Sphingolipid receptor signaling and function in human bladder carcinoma cells: inhibition of LPA- but enhancement of thrombin-stimulated cell motility. |
2000 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:10651140
|
Lee OH et al. |
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10652210
|
Sato K et al. |
Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells. |
2000 |
Brain Res. Mol. Brain Res. |
pmid:11146117
|
Hla T et al. |
Sphingosine-1-phosphate signaling via the EDG-1 family of G-protein-coupled receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818438
|
Spiegel S |
Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818441
|
Ancellin N and Hla T |
Switching intracellular signaling pathways to study sphingosine 1-phosphate receptors. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818459
|
Yamamura S et al. |
Sphingosine-1-phosphate inhibits haptotactic motility by overproduction of focal adhesion sites in B16 melanoma cells through EDG-induced activation of Rho. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818470
|
Gallois C et al. |
Endothelin-1 stimulates sphingosine kinase in human hepatic stellate cells. A novel role for sphingosine-1-P as a mediator of growth inhibition. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818472
|
Gennero I et al. |
Effect of sphingosine-1-phosphate and analogues of lysophosphatidic acid on mesangial cell proliferation. |
2000 |
Ann. N. Y. Acad. Sci. |
pmid:10818478
|
Alessenko AV |
The role of sphingomyelin cycle metabolites in transduction of signals of cell proliferation, differentiation and death. |
2000 |
Membr Cell Biol |
pmid:10779176
|
Miura Y et al. |
Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets. |
2000 |
J. Biochem. |
pmid:10788802
|
Im DS et al. |
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. |
2000 |
J. Biol. Chem. |
pmid:10799507
|
Boguslawski G et al. |
Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10833459
|
Kimura T et al. |
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. |
2000 |
Biochem. J. |
pmid:10794715
|
Van Brocklyn JR et al. |
Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6. |
2000 |
Blood |
pmid:10753843
|
English D et al. |
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. |
2000 |
FASEB J. |
pmid:11053247
|
Edsall L et al. |
Enzymatic method for measurement of sphingosine 1-phosphate. |
2000 |
Meth. Enzymol. |
pmid:11070858
|
Sullards MC |
Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry. |
2000 |
Meth. Enzymol. |
pmid:11070861
|
Van Brocklyn JR and Spiegel S |
Binding of sphingosine 1-phosphate to cell surface receptors. |
2000 |
Meth. Enzymol. |
pmid:11070888
|
Yatomi Y et al. |
Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells. |
2000 |
Blood |
pmid:11071638
|
Fukushima N |
[A family of lysophospholipid receptors]. |
2000 |
Seikagaku |
pmid:11076202
|
Meacci E et al. |
Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts. |
2000 |
FEBS Lett. |
pmid:11018530
|
Kozawa O et al. |
Enhancement by sphingosine 1-phosphate in vasopressin-induced phosphoinositide hydrolysis in aortic smooth-muscle cells: involvement of p38 MAP kinase. |
2000 |
J. Cell. Biochem. |
pmid:11029753
|
Sato TN |
A new role of lipid receptors in vascular and cardiac morphogenesis. |
2000 |
J. Clin. Invest. |
pmid:11032853
|
Liu Y et al. |
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. |
2000 |
J. Clin. Invest. |
pmid:11032855
|
Xia P et al. |
An oncogenic role of sphingosine kinase. |
2000 |
Curr. Biol. |
pmid:11114522
|
Okamoto H et al. |
Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. |
2000 |
Mol. Cell. Biol. |
pmid:11094076
|
Murata N et al. |
Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. |
2000 |
Biochem. J. |
pmid:11104690
|
Shimizu H et al. |
Sphingosine 1-phosphate stimulates insulin secretion in HIT-T 15 cells and mouse islets. |
2000 |
Endocr. J. |
pmid:11036869
|
MacLennan AJ et al. |
Antisense studies in PC12 cells suggest a role for H218, a sphingosine 1-phosphate receptor, in growth-factor-induced cell-cell interaction and neurite outgrowth. |
2000 |
Dev. Neurosci. |
pmid:10965150
|
Nakajima N et al. |
Expression and characterization of Edg-1 receptors in rat cardiomyocytes: calcium deregulation in response to sphingosine 1-phosphate. |
2000 |
Eur. J. Biochem. |
pmid:10971577
|
Parrill AL et al. |
Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate. |
2000 |
J. Biol. Chem. |
pmid:10982820
|
Davaille J et al. |
Antiproliferative properties of sphingosine 1-phosphate in human hepatic myofibroblasts. A cyclooxygenase-2 mediated pathway. |
2000 |
J. Biol. Chem. |
pmid:10942778
|
Pitson SM et al. |
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase. |
2000 |
J. Biol. Chem. |
pmid:10944534
|
Nugent D and Xu Y |
Sphingosine-1-phosphate: characterization of its inhibition of platelet aggregation. |
2000 |
Platelets |
pmid:10938902
|
Young KW et al. |
Effect of dimethylsphingosine on muscarinic M(3) receptor signalling in SH-SY5Y cells. |
2000 |
Eur. J. Pharmacol. |
pmid:10940357
|
Shin Y et al. |
Diverse effects of sphingosine on calcium mobilization and influx in differentiated HL-60 cells. |
2000 |
Cell Calcium |
pmid:10859593
|
Casper RF and Jurisicova A |
Protecting the female germ line from cancer therapy. |
2000 |
Nat. Med. |
pmid:11017136
|
Morita Y et al. |
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. |
2000 |
Nat. Med. |
pmid:11017141
|
Himmel HM et al. |
Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes. |
2000 |
Mol. Pharmacol. |
pmid:10908314
|
Driever W |
Developmental biology. Bringing two hearts together. |
2000 |
Nature |
pmid:10910341
|
Kupperman E et al. |
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. |
2000 |
Nature |
pmid:10910360
|
Mandala SM et al. |
Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10859351
|
Meacci E et al. |
Receptor-activated phospholipase D is present in caveolin-3-enriched light membranes of C2C12 myotubes. |
2000 |
FEBS Lett. |
pmid:10802049
|
Murata N et al. |
Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay. |
2000 |
Anal. Biochem. |
pmid:10860507
|
Siess W et al. |
Lysophosphatidic acid and sphingosine 1-phosphate: two lipid villains provoking cardiovascular diseases? |
2000 |
IUBMB Life |
pmid:10868905
|
Caligan TB et al. |
A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples. |
2000 |
Anal. Biochem. |
pmid:10847608
|
Igarashi J and Michel T |
Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction. |
2000 |
J. Biol. Chem. |
pmid:10921915
|
Racké K et al. |
Potential role of EDG receptors and lysophospholipids as their endogenous ligands in the respiratory tract. |
2000 |
Pulm Pharmacol Ther |
pmid:10873548
|
Sugiyama A et al. |
Effects of sphingosine 1-phosphate, a naturally occurring biologically active lysophospholipid, on the rat cardiovascular system. |
2000 |
Jpn. J. Pharmacol. |
pmid:10875754
|
Spiegel S and Milstien S |
Sphingosine-1-phosphate: signaling inside and out. |
2000 |
FEBS Lett. |
pmid:10878250
|
Cooke ME et al. |
Contraction of collagen matrices mediated by alpha2beta1A and alpha(v)beta3 integrins. |
2000 |
J. Cell. Sci. |
pmid:10852817
|
Yanai N et al. |
Sphingosine-1-phosphate and lysophosphatidic acid trigger invasion of primitive hematopoietic cells into stromal cell layers. |
2000 |
Blood |
pmid:10891442
|
Prieschl EE and Baumruker T |
Beyond a structural component: sphingolipids in immunology. |
2000 |
Arch. Immunol. Ther. Exp. (Warsz.) |
pmid:10912620
|
Ikeda H et al. |
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells. |
2000 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:10915638
|
Yamazaki Y et al. |
Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10679247
|
Lee H et al. |
Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. |
2000 |
Am. J. Physiol., Cell Physiol. |
pmid:10712250
|
Kim JH et al. |
Sphingosine 1-phosphate activates Erk-1/-2 by transactivating epidermal growth factor receptor in rat-2 cells. |
2000 |
IUBMB Life |
pmid:11185956
|
Motohashi K et al. |
Identification of lysophospholipid receptors in human platelets: the relation of two agonists, lysophosphatidic acid and sphingosine 1-phosphate. |
2000 |
FEBS Lett. |
pmid:10692584
|
Sugiyama A et al. |
Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart. |
2000 |
Cardiovasc. Res. |
pmid:10727660
|
Kozawa O et al. |
Sphingosine 1-phosphate amplifies phosphoinositide hydrolysis stimulated by prostaglandin f2 alpha in osteoblasts: involvement of p38MAP kinase. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10913228
|
Orlati S et al. |
Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor. |
2000 |
Arch. Biochem. Biophys. |
pmid:10683250
|
Okamoto H et al. |
Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. |
2000 |
Thromb. Res. |
pmid:10942792
|
Takeshita A et al. |
Selective stimulation by ceramide of the expression of the alpha isoform of retinoic acid and retinoid X receptors in osteoblastic cells. A role of sphingosine 1-phosphate-mediated AP-1 in the ligand-dependent transcriptional activity of these receptors. |
2000 |
J. Biol. Chem. |
pmid:10915783
|