Sphingosine 1-phosphate
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis.
Cross Reference
Introduction
To understand associated biological information of Sphingosine 1-phosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Sphingosine 1-phosphate?
Sphingosine 1-phosphate is suspected in Lymphopenia, Ischemia, Infection, Atherosclerosis, Multiple Sclerosis, Asthma and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Sphingosine 1-phosphate
PubChem Associated disorders and diseases
What pathways are associated with Sphingosine 1-phosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Sphingosine 1-phosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Sphingosine 1-phosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Sphingosine 1-phosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Sphingosine 1-phosphate?
Knock-out
Knock-out are used in the study 'Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkappaB-inducing kinase in stromal cells.' (Kunisawa J et al., 2008), Knock-out are used in the study 'Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.' (Markiewicz M et al., 2011), Knock-out are used in the study 'Chasing sphingosine-1-phosphate, a lipid mediator for cardiomyocyte survival.' (Yang Q, 2007), Knock-out are used in the study 'Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function.' (Idzko M et al., 2006) and Knock-out are used in the study 'Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho.' (Gratzinger D et al., 2003).
Mouse Model
Mouse Model are used in the study 'Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin.' (Arce FT et al., 2008), Mouse Model are used in the study 'Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis.' (Tengood JE et al., 2010), Mouse Model are used in the study 'S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells.' (Chang CL et al., 2009), Mouse Model are used in the study 'Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.' (Hughes JE et al., 2008) and Mouse Model are used in the study 'The alliance of sphingosine-1-phosphate and its receptors in immunity.' (Rivera J et al., 2008).
Transgenic Model
Transgenic Model are used in the study 'Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.' (Augé N et al., 2004), Transgenic Model are used in the study 'Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration.' (Sabbadini RA, 2011) and Transgenic Model are used in the study 'Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy.' (Gault CR and Obeid LM, 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Sphingosine 1-phosphate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kulinski JM et al. | Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. | 2016 | Eur. J. Pharmacol. | pmid:25941085 |
| Lei YC et al. | C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure. | 2016 | World J. Gastroenterol. | pmid:28028363 |
| Al Fadel F et al. | Involvement of Sphingosine 1-Phosphate in Palmitate-Induced Non-Alcoholic Fatty Liver Disease. | 2016 | Cell. Physiol. Biochem. | pmid:28006772 |
| Bigaud M et al. | Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism. | 2016 | PLoS ONE | pmid:28005953 |
| Kasbi-Chadli F et al. | Direct and maternal n-3 long-chain polyunsaturated fatty acid supplementation improved triglyceridemia and glycemia through the regulation of hepatic and muscle sphingolipid synthesis in offspring hamsters fed a high-fat diet. | 2016 | Eur J Nutr | pmid:25787885 |
| Gharbaran R | Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma. | 2016 | Tumour Biol. | pmid:27317256 |
| Higashi K et al. | Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts. | 2016 | Bone | pmid:27612439 |
| Sasset L et al. | Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. | 2016 | Trends Endocrinol. Metab. | pmid:27562337 |
| Roviezzo F et al. | Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate. | 2016 | Pharmacol. Res. | pmid:27713021 |
| Hemdan NY et al. | Modulating sphingosine 1-phosphate signaling with DOP or FTY720 alleviates vascular and immune defects in mouse sepsis. | 2016 | Eur. J. Immunol. | pmid:27683081 |
| Kemppainen K et al. | Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. | 2016 | Cell. Signal. | pmid:27634386 |
| Custódio R et al. | Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei. | 2016 | Mol. Microbiol. | pmid:27632710 |
| Ebenezer DL et al. | Targeting sphingosine-1-phosphate signaling in lung diseases. | 2016 | Pharmacol. Ther. | pmid:27621206 |
| Tsuchida J et al. | Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis. | 2016 | J. Surg. Res. | pmid:27621003 |
| Chen W et al. | Sphingosine 1-phosphate in metabolic syndrome (Review). | 2016 | Int. J. Mol. Med. | pmid:27600830 |
| Chen C et al. | Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. | 2016 | Mol. Cell. Endocrinol. | pmid:26948947 |
| Rodvold JJ and Zanetti M | Tumor microenvironment on the move and the Aselli connection. | 2016 | Sci Signal | pmid:27353363 |
| Harijith A et al. | Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27343196 |
| Hernández-Coronado CG et al. | Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. | 2016 | Gen. Comp. Endocrinol. | pmid:27342378 |
| Chakrabarti SS et al. | Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease. | 2016 | Curr Alzheimer Res | pmid:27335046 |
| Tsai HC and Han MH | Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation. | 2016 | Drugs | pmid:27318702 |
| Yang Z et al. | TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells. | 2016 | Pharmacol. Res. | pmid:27317945 |
| Cantalupo A and Di Lorenzo A | S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis. | 2016 | J. Pharmacol. Exp. Ther. | pmid:27317800 |
| Frej C et al. | Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. | 2016 | J. Cell. Mol. Med. | pmid:26990127 |
| Pyne S et al. | Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances. | 2016 | Prog. Lipid Res. | pmid:26970273 |
| Aoki M et al. | Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential. | 2016 | Mediators Inflamm. | pmid:26966342 |
| Brinck JW et al. | Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection. | 2016 | Arterioscler. Thromb. Vasc. Biol. | pmid:26966278 |
| Chawla S et al. | S1P prophylaxis mitigates acute hypobaric hypoxia-induced molecular, biochemical, and metabolic disturbances: A preclinical report. | 2016 | IUBMB Life | pmid:26959531 |
| Vito CD et al. | Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications. | 2016 | Platelets | pmid:26950429 |
| Chapurlat RD and Confavreux CB | Novel biological markers of bone: from bone metabolism to bone physiology. | 2016 | Rheumatology (Oxford) | pmid:26790456 |
| Zhang Y et al. | Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. | 2016 | PLoS ONE | pmid:26788916 |
| Dillmann C et al. | S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. | 2016 | J. Immunol. | pmid:26783340 |
| Ghasemi R et al. | Integrated sphingosine-1 phosphate signaling in the central nervous system: From physiological equilibrium to pathological damage. | 2016 | Pharmacol. Res. | pmid:26772814 |
| Morel S et al. | Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43. | 2016 | Cardiovasc. Res. | pmid:26762268 |
| Sundaram K et al. | Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death. | 2016 | Biochem. J. | pmid:26747710 |
| Abu Khweek A et al. | The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. | 2016 | PLoS ONE | pmid:26741365 |
| Realini N et al. | Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION. | 2016 | J. Biol. Chem. | pmid:26553872 |
| Campos LS et al. | Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling. | 2016 | Mol. Cell. Biol. | pmid:26552704 |
| Cheng JC et al. | Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. | 2016 | Cell. Signal. | pmid:26994820 |
| Liu X et al. | Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. | 2016 | Exp. Biol. Med. (Maywood) | pmid:26376826 |
| Filipenko I et al. | Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. | 2016 | Biochim. Biophys. Acta | pmid:27616330 |
| Powell JA et al. | Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. | 2017 | Blood | pmid:27956387 |
| Miyabe C et al. | A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. | 2017 | Inflamm. Res. | pmid:27942751 |
| Williams PA et al. | Alginate-Chitosan Hydrogels Provide a Sustained Gradient of Sphingosine-1-Phosphate for Therapeutic Angiogenesis. | 2017 | Ann Biomed Eng | pmid:27904998 |
| Mao-Draayer Y et al. | The sphingosine-1-phosphate receptor: A novel therapeutic target for multiple sclerosis and other autoimmune diseases. | 2017 | Clin. Immunol. | pmid:27890706 |
| Lee MH et al. | S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. | 2017 | J. Lipid Res. | pmid:27881715 |
| Ruiz M et al. | High-Density Lipoprotein-Associated Apolipoprotein M Limits Endothelial Inflammation by Delivering Sphingosine-1-Phosphate to the Sphingosine-1-Phosphate Receptor 1. | 2017 | Arterioscler. Thromb. Vasc. Biol. | pmid:27879252 |
| Barnawi J et al. | Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. | 2017 | Respirology | pmid:27868302 |
| Frias MA et al. | High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. | 2017 | Eur. J. Clin. Invest. | pmid:27861771 |
| Fang V et al. | Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. | 2017 | Nat. Immunol. | pmid:27841869 |
| Wang R et al. | Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. | 2017 | Am. J. Pathol. | pmid:27840081 |
| Vogt D and Stark H | Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. | 2017 | Med Res Rev | pmid:27480072 |
| Olesch C et al. | Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell Activation. | 2017 | Mediators Inflamm. | pmid:28848247 |
| Egom EE et al. | Determination of Sphingosine-1-Phosphate in Human Plasma Using Liquid Chromatography Coupled with Q-Tof Mass Spectrometry. | 2017 | Int J Mol Sci | pmid:28820460 |
| Swendeman SL et al. | An engineered S1P chaperone attenuates hypertension and ischemic injury. | 2017 | Sci Signal | pmid:28811382 |
| Syed SN et al. | S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1 or Lipocalin-2. | 2017 | Mediators Inflamm. | pmid:28804221 |
| Doan NB et al. | Acid ceramidase confers radioresistance to glioblastoma cells. | 2017 | Oncol. Rep. | pmid:28765947 |
| Arish M et al. | Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies. | 2017 | J. Recept. Signal Transduct. Res. | pmid:28758826 |
| Polzin A et al. | Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease. | 2017 | J. Mol. Cell. Cardiol. | pmid:28709768 |
| Innamorati G et al. | Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. | 2017 | Cell Death Dis | pmid:28703804 |
| Bougault C et al. | Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. | 2017 | Bone | pmid:28684192 |
| Tsai CH et al. | Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. | 2017 | Mol Oncol | pmid:28672103 |
| Schmidt KG et al. | Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study. | 2017 | Front Immunol | pmid:29033951 |
| Xie Z et al. | Targeting sphingosine-1-phosphate signaling for cancer therapy. | 2017 | Sci China Life Sci | pmid:28623546 |
| Yanagida K et al. | Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:28396408 |
| Takahashi C et al. | Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. | 2017 | J. Atheroscler. Thromb. | pmid:28321011 |
| Vu TM et al. | Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. | 2017 | Nature | pmid:29045386 |
| Kurano M et al. | Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. | 2017 | PLoS ONE | pmid:28494002 |
| Zeng Y | Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling. | 2017 | J. Cell. Mol. Med. | pmid:28211170 |
| Sun XJ et al. | Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis. | 2017 | Nephrol. Dial. Transplant. | pmid:28206609 |
| Janecke AR et al. | Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. | 2017 | Hum. Mutat. | pmid:28181337 |
| Moritz E et al. | Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. | 2017 | Clin. Chim. Acta | pmid:28159438 |
| Winkler MS et al. | Sphingosine-1-Phosphate: A Potential Biomarker and Therapeutic Target for Endothelial Dysfunction and Sepsis? | 2017 | Shock | pmid:27922551 |
| Al-Jarallah A and Oriowo M | The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. | 2017 | PLoS ONE | pmid:28493876 |
| Chen T et al. | Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. | 2017 | Front Biosci (Landmark Ed) | pmid:27814635 |
| Beider K et al. | The Sphingosine-1-Phosphate Modulator FTY720 Targets Multiple Myeloma via the CXCR4/CXCL12 Pathway. | 2017 | Clin. Cancer Res. | pmid:27697999 |
| Thieme M et al. | Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. | 2017 | Exp. Dermatol. | pmid:27574180 |
| Chang CH and Randolph GJ | Sphingosine-1-Phosphate as the Lymphocyte's Ticket to Ride and Survive. | 2017 | Dev. Cell | pmid:28633013 |
| Fang R et al. | Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3β Phosphorylation. | 2017 | Arch. Med. Res. | pmid:28625317 |
| Rohrbach T et al. | Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology. | 2017 | Crit. Rev. Biochem. Mol. Biol. | pmid:28618839 |
| Vijayan M et al. | Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. | 2017 | J. Immunol. | pmid:28600291 |
| White CR et al. | High-Density Lipoprotein Regulation of Mitochondrial Function. | 2017 | Adv. Exp. Med. Biol. | pmid:28551800 |
| Dany M and Elston D | Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. | 2017 | J. Am. Acad. Dermatol. | pmid:28551069 |
| Mendoza A et al. | Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. | 2017 | Nature | pmid:28538737 |
| Ma S et al. | A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. | 2017 | Dev. Cell | pmid:28535372 |
| Meshcheryakova A et al. | Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. | 2017 | Expert Opin. Ther. Targets | pmid:28524744 |
| Ko J et al. | Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. | 2017 | Invest. Ophthalmol. Vis. Sci. | pmid:28492873 |
| Tafelmeier M et al. | Mildly oxidized HDL decrease agonist-induced platelet aggregation and release of pro-coagulant platelet extracellular vesicles. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27163393 |
| Serafimidis I et al. | Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. | 2017 | PLoS Biol. | pmid:28248965 |
| Lee HM et al. | Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. | 2017 | J. Pathol. | pmid:28240350 |
| Rieck M et al. | Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. | 2017 | Eur. J. Immunol. | pmid:28198542 |
| Bruno M et al. | Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. | 2017 | Biochim. Biophys. Acta | pmid:28188805 |
| Qi H et al. | Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. | 2017 | J. Lipid Res. | pmid:28188148 |
| Ren K et al. | ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. | 2017 | J. Physiol. Biochem. | pmid:28181168 |
| Ruiz M et al. | HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. | 2017 | Lipids Health Dis | pmid:28179022 |
| Moruno-Manchon JF et al. | Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. | 2017 | Hum. Mol. Genet. | pmid:28175299 |
| Rojas-Canales D et al. | Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. | 2017 | Diabetes | pmid:28174291 |
| Dela Paz NG et al. | Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. | 2017 | Am. J. Physiol., Cell Physiol. | pmid:28148497 |
| Green CL et al. | The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. | 2017 | Aging Cell | pmid:28139067 |
| Vishwakarma S et al. | Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. | 2017 | Cancer Invest. | pmid:28135860 |