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Biochim. Biophys. Acta |
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Assessment of the role of sphingosine 1-phosphate and its receptors in high-density lipoprotein-induced stimulation of astroglial cell function. |
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Diabetes |
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Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm. |
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Biol. Neonate |
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Synthesis of para-alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists. |
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J Biomol Screen |
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Brain Res. |
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Mol. Pharmacol. |
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Exogenous and intracellularly generated sphingosine 1-phosphate can regulate cellular processes by divergent pathways. |
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Biochem. Soc. Trans. |
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Sphingosine-1-phosphate is a high-affinity ligand for the G protein-coupled receptor GPR6 from mouse and induces intracellular Ca2+ release by activating the sphingosine-kinase pathway. |
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Biochem. Biophys. Res. Commun. |
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Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis. |
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Arch. Pharm. Res. |
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Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels. |
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Biochem. Pharmacol. |
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Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells. |
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Biochem. J. |
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Ceramide 1-phosphate increases intracellular free calcium concentrations in thyroid FRTL-5 cells: evidence for an effect mediated by inositol 1,4,5-trisphosphate and intracellular sphingosine 1-phosphate. |
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Biochem. J. |
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Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve. |
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J. Neuropathol. Exp. Neurol. |
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Synthesis of fluorescence-labeled sphingosine and sphingosine 1-phosphate; effective tools for sphingosine and sphingosine 1-phosphate behavior. |
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Bioorg. Med. Chem. Lett. |
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Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells. |
2003 |
Cell. Physiol. Biochem. |
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Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages. |
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FEBS Lett. |
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Arterioscler. Thromb. Vasc. Biol. |
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S1P3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate. |
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Eur. J. Pharmacol. |
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Protein kinase C epsilon dependence of the recovery from down-regulation of S1P1 G protein-coupled receptors of T lymphocytes. |
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Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells. |
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Cancer Lett. |
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Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. |
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Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm. |
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Curr Opin Chem Biol |
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Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation. |
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Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: differential interaction with protein targets. |
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