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Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. |
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Serum-Sphingosine-1-Phosphate Concentrations Are Inversely Associated with Atherosclerotic Diseases in Humans. |
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α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization. |
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Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. |
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Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells. |
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Kowalski GM et al. |
Plasma sphingosine-1-phosphate is elevated in obesity. |
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Zhao S and Li J |
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
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Sphingosine-1-phosphate mediates ICAM-1-dependent monocyte adhesion through p38 MAPK and p42/p44 MAPK-dependent Akt activation. |
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Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice. |
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Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. |
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Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. |
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Insulin protects apoptotic cardiomyocytes from hypoxia/reoxygenation injury through the sphingosine kinase/sphingosine 1-phosphate axis. |
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Sphingosine 1-phosphate in acute dengue infection. |
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Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. |
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PLoS ONE |
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Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures. |
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Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells. |
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PLoS ONE |
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Bachmaier K et al. |
Sphingosine kinase 1 mediation of expression of the anaphylatoxin receptor C5L2 dampens the inflammatory response to endotoxin. |
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Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. |
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A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. |
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Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation. |
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PLoS ONE |
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Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6. |
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Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. |
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Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids. |
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Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival. |
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Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects. |
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The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. |
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Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction. |
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Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development. |
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Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate. |
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Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate. |
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Sphingosine-1-Phosphate as a Regulator of Hypoxia-Induced Factor-1α in Thyroid Follicular Carcinoma Cells. |
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Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. |
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Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. |
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Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication. |
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A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung. |
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Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. |
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Reduction in serum sphingosine 1-phosphate concentration in malaria. |
2017 |
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The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries. |
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LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor. |
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Enhancement of neoangiogenesis and follicle survival by sphingosine-1-phosphate in human ovarian tissue xenotransplants. |
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Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli? |
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PLoS ONE |
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Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. |
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Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophages. |
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GPR3 receptor, a novel actor in the emotional-like responses. |
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