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Cardiovasc. Res. |
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Am. J. Physiol. Heart Circ. Physiol. |
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Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3. |
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The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. |
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FASEB J. |
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The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis. |
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Immunity |
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Sphingosine 1-phosphate stimulation of NADPH oxidase activity: relationship with platelet-derived growth factor receptor and c-Src kinase. |
2007 |
Biochim. Biophys. Acta |
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S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells. |
2007 |
Biochem. Biophys. Res. Commun. |
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Differential effects of G protein coupled receptors on hematopoietic progenitor cell growth depend on their signaling capacities. |
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Ann. N. Y. Acad. Sci. |
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Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again. |
2007 |
Cell Cycle |
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Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. |
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Science |
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Biochemistry Mosc. |
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Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E2 from human articular chondrocytes. |
2007 |
BMC Musculoskelet Disord |
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Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness. |
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Exp. Cell Res. |
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Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. |
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Life Sci. |
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Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and tumor cell migration. |
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Sphingosine 1-phosphate inhibits ischemia reperfusion injury following experimental lung transplantation. |
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Am. J. Transplant. |
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Sphingosine 1-phosphate in neural signalling and function. |
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Acta Paediatr Suppl |
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2007 |
Acta Paediatr Suppl |
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Sphingosine 1-phosphate as an intracellular messenger and extracellular mediator in immunity. |
2007 |
Acta Paediatr Suppl |
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The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3). |
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J. Thromb. Haemost. |
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Modulation of human arterial tone during pregnancy: the effect of the bioactive metabolite sphingosine-1-phosphate. |
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Biol. Reprod. |
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Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes. |
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Biochem. Biophys. Res. Commun. |
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Letter by Xia regarding article, "High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor". |
2007 |
Circulation |
pmid:17420358
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Jacobson JR and Garcia JG |
Novel therapies for microvascular permeability in sepsis. |
2007 |
Curr Drug Targets |
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Immunology. The sources of a lipid conundrum. |
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Science |
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Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. |
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Arterioscler. Thromb. Vasc. Biol. |
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PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. |
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Cutting edge: Alternative signaling of Th17 cell development by sphingosine 1-phosphate. |
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J. Immunol. |
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Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate. |
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Prog. Lipid Res. |
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Sphingosine-1-phosphate and the immunosuppressant, FTY720-phosphate, regulate detrusor muscle tone. |
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FASEB J. |
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Sphingosine 1-phosphate triggers apoptotic signal for B16 melanoma cells via ERK and caspase activation. |
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J. Korean Med. Sci. |
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Sphingosine 1-phosphate mediates proliferation and survival of mesoangioblasts. |
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Stem Cells |
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Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences. |
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J. Mol. Graph. Model. |
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Development of a simple and robust assay to screen for inhibitors of sphingosine kinases. |
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Assay Drug Dev Technol |
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Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. |
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Arch. Pharm. Res. |
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Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors. |
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Naunyn Schmiedebergs Arch. Pharmacol. |
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Partial hepatectomy activates production of the pro-mitotic intermediates of the sphingomyelin signal transduction pathway in the rat liver. |
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Prostaglandins Other Lipid Mediat. |
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[Measurement of sphingosine 1-phosphate as a biomarker of atherosclerosis]. |
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Rinsho Byori |
pmid:17511266
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Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cells. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17512899
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Th17 augmentation in OTII TCR plus T cell-selective type 1 sphingosine 1-phosphate receptor double transgenic mice. |
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J. Immunol. |
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Does sphingosine-1-phosphate have a protective effect on cyclophosphamide- and irradiation-induced ovarian damage in the rat model? |
2008 |
Fertil. Steril. |
pmid:17517398
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Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. |
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J. Biol. Chem. |
pmid:17519230
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Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. |
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Mol. Cancer Res. |
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HDL-like lipoproteins in cerebrospinal fluid affect neural cell activity through lipoprotein-associated sphingosine 1-phosphate. |
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Biochem. Biophys. Res. Commun. |
pmid:17544365
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The immunomodulator FTY720 is phosphorylated and released from platelets. |
2007 |
Eur. J. Pharmacol. |
pmid:17553484
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Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury. |
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Kidney Int. |
pmid:17554348
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Keul P et al. |
HDL and its sphingosine-1-phosphate content in cardioprotection. |
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Heart Fail Rev |
pmid:17554629
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