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Respirology |
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Neuropharmacology |
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A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. |
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Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. |
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Med Res Rev |
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Mol Oncol |
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Neuropharmacology |
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The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. |
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A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
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The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
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Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. |
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Immunology |
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Gastroenterology |
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The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. |
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Aging Cell |
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Hepatology |
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Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts. |
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Bone |
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Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. |
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Cell Calcium |
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Targeting sphingosine-1-phosphate signaling in lung diseases. |
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Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α. |
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Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection. |
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Pathog Dis |
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Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis. |
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Sci Signal |
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Tumor microenvironment on the move and the Aselli connection. |
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Sci Signal |
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Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. |
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Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation. |
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Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human TÂ cells from the thymus to the periphery. |
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Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). |
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Potential serum biomarkers from a metabolomics study of autism. |
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J Psychiatry Neurosci |
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Sphingosine 1-phosphate signaling in astrocytes: Implications for progressive multiple sclerosis. |
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The influence of metal-based biomaterials functionalized with sphingosine-1-phosphate on the cellular response and osteogenic differentaion potenial of human adipose derived mesenchymal stem cells in vitro. |
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J Biomater Appl |
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Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. |
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Novel biological markers of bone: from bone metabolism to bone physiology. |
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Rheumatology (Oxford) |
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Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. |
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PLoS ONE |
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S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. |
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Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling. |
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Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. |
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Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells. |
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Stem Cell Rev |
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FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. |
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Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells. |
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IL-15 boosts the function and migration of human terminally differentiated CD8+ T cells by inducing a unique gene signature. |
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