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K6PC-5, a novel sphingosine kinase 1 (SphK1) activator, alleviates dexamethasone-induced damages to osteoblasts through activating SphK1-Akt signaling. |
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Modulation of the expression of sphingosine 1-phosphate 2 receptors regulates the differentiation of pre-adipocytes. |
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Migration of germline progenitor cells is directed by sphingosine-1-phosphate signalling in a basal chordate. |
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J Neuroinflammation |
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J Neuroinflammation |
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Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720. |
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HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation. |
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Sci Signal |
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Evidence for fumonisin inhibition of ceramide synthase in humans consuming maize-based foods and living in high exposure communities in Guatemala. |
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Mol Nutr Food Res |
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GluN2B-containing NMDA receptors are upregulated in plasma membranes by the sphingosine-1-phosphate analog FTY720P. |
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Brain Res. |
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Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. |
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Oncotarget |
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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. |
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Sci Signal |
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Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. |
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PLoS ONE |
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Role of N-WASP in Endothelial Monolayer Formation and Integrity. |
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HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation. |
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Nature |
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Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis. |
2015 |
Biomaterials |
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Pericyte chemomechanics and the angiogenic switch: insights into the pathogenesis of proliferative diabetic retinopathy? |
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