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Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. |
2014 |
Dis Model Mech |
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Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model. |
2014 |
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Anderson G and Maes M |
Reconceptualizing adult neurogenesis: role for sphingosine-1-phosphate and fibroblast growth factor-1 in co-ordinating astrocyte-neuronal precursor interactions. |
2014 |
CNS Neurol Disord Drug Targets |
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2014 |
Circ. J. |
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Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells. |
2014 |
Mol. Hum. Reprod. |
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Sphingosine 1-phosphate in acute dengue infection. |
2014 |
PLoS ONE |
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FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway. |
2014 |
Acta Pharmacol. Sin. |
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Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. |
2014 |
J. Med. Chem. |
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2014 |
J. Pharmacol. Sci. |
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2014 |
Mol. Endocrinol. |
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Sphingosine-1-phosphate promotes extravillous trophoblast cell invasion by activating MEK/ERK/MMP-2 signaling pathways via S1P/S1PR1 axis activation. |
2014 |
PLoS ONE |
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2014 |
Immunity |
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2014 |
FASEB J. |
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Vitamin D therapy in experimental allergic encephalomyelitis could be limited by opposing effects of sphingosine 1-phosphate and gelsolin dysregulation. |
2014 |
Mol. Neurobiol. |
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2014 |
PLoS ONE |
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Tissue Eng Part C Methods |
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Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. |
2014 |
Mol. Neurobiol. |
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4-Deoxypyridoxine improves the viability of isolated pancreatic islets ex vivo. |
2013 May-Jun |
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Activation of sphingosine-1-phosphate signalling as a potential underlying mechanism of the pleiotropic effects of statin therapy. |
2013 May-Jun |
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An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1-phosphate. |
2013 Jul-Aug |
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2013 Jan-Feb |
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PPARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. |
2013 |
Biochim. Biophys. Acta |
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2013 |
Nature |
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2013 |
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Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development. |
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J. Biol. Chem. |
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Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK). |
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The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages. |
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Oncogene |
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The role of sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) in regulation of osteoclastic and osteoblastic cells. |
2013 |
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ETS-1-mediated transcriptional up-regulation of CD44 is required for sphingosine-1-phosphate receptor subtype 3-stimulated chemotaxis. |
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Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics. |
2013 |
Integr Biol (Camb) |
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Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence. |
2013 |
Mol. Microbiol. |
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Epidermal growth factor receptor signaling-dependent calcium elevation in cumulus cells is required for NPR2 inhibition and meiotic resumption in mouse oocytes. |
2013 |
Endocrinology |
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Molecular basis of sphingosine kinase 1 substrate recognition and catalysis. |
2013 |
Structure |
pmid:23602659
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Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model. |
2013 |
Integr Biol (Camb) |
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Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation. |
2013 |
FASEB J. |
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Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain. |
2013 |
Trends Pharmacol. Sci. |
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Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis. |
2013 |
PLoS ONE |
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Sphingosine-1-phosphate protects against bisphosphonate‑induced HUVEC cell death via regulation of c-Jun‑N‑terminal kinase signaling. |
2013 |
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2013 |
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Fingolimod protects cultured cortical neurons against excitotoxic death. |
2013 |
Pharmacol. Res. |
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2013 |
Handb Exp Pharmacol |
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2013 |
Adv. Cancer Res. |
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2013 |
Adv. Cancer Res. |
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2013 |
Adv. Cancer Res. |
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Dose-dependent effect of aspirin on the level of sphingolipids in human blood. |
2013 |
Adv Med Sci |
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